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Functional Neonatal Echocardiography in
               Haemodynamic Disturbancies



                                Jana Semberova
              Institute for the Care of Mother and Child, Prague,
                                 Czech Republic




The HIP Trial is funded by the European Commission within the 7th Framework Programme
What can we see on echo when something goes
                       wrong




The HIP Trial is funded by the European Commission within the 7th Framework Programme
Bedside neonatal echocardiography

• Targeted neonatal echocardiography
• Point of care echocardiography (POCT echo)
• Functional echocardiography




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
WHY to perform the scan

• Circulatory failure – major cause of neonatal morbidity
  and mortality
• Measures currently used to assess circulatory status
  often inadequate
• Circulation management varies widely
• Lack of standardized approach
• Echo can help to assess haemodynamic status and
  perhaps to guide treatment




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
WHEN to perform the scan?

• Routine (e.g. PDA assesment)
• Clinical status

• Functional assessment – findings may change over
  time, sometimes very quickly




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
The role of functional Echo

•     Structure – exclude CHD
•     PDA
•     PPHN
•     Filling, contractility, flow
•     Other: Pericardial fluid, line position etc.




    The HIP Trial is funded by the European Commission within the 7th Framework Programme
CHD - TOF




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
CHD - VSD




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
PDA – Left to Right




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
PDA - Bidirectional




  The HIP Trial is funded by the European Commission within the 7th Framework Programme
PDA – flow pattern, pressure gradient




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
PDA heart failure




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
Pulmonary Hypertension




  The HIP Trial is funded by the European Commission within the 7th Framework Programme
PPHN - TVI




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
Contractility assessment




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
Good Contractility




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
Poor Contractility




  The HIP Trial is funded by the European Commission within the 7th Framework Programme
Hypertrophy




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
LVOTO




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
Filling (preload assessment – extracardiac IVC filling)




The HIP Trial is funded by the European Commission within the 7th Framework Programme
Pericardial fluid




  The HIP Trial is funded by the European Commission within the 7th Framework Programme
Line position




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
Abdominal Aorta Flow


                                                            Normal Finding




                                                            Significant Left to Right Shunt - PDA




                                                            Coarctation of the Aorta




                                                             Low LV Output – Heart Failure
The HIP Trial is funded by the European Commission within the 7th Framework Programme
Other findings

•     Air embolia
•     Tumor
•     Thrombus
•     Etc….




    The HIP Trial is funded by the European Commission within the 7th Framework Programme
Functional assessment

•     Quantification and normative values
•     LVO, RVO – influenced by shunts
•     SVC flow, SF, EF
•     TDI, strain, strain rate, speckle tracking – not used
      routinely in neonates, more research tools

• Visual assesment (Eyeballing)




    The HIP Trial is funded by the European Commission within the 7th Framework Programme
The HIP Trial is funded by the European Commission within the 7th Framework Programme
Management
according to Echo findings ???

What to do with what we find

• Fluid administration
• Inotrope administration
• Clinical status!

• So far limited evidence of outcome improvement




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
Evolution over the time

     Day 1                                             Day 7                            Day 38




The HIP Trial is funded by the European Commission within the 7th Framework Programme
Evolution over the time




         FS 19%                                                                     FS 36%




  The HIP Trial is funded by the European Commission within the 7th Framework Programme
• CLOSE COOPERATION WITH PEDIATRIC
  CARDIOLOGIST CRUCIAL

• Practice, recognition and availability of functional
  neonatal echo varies among countries/centers




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
TNE Guidelines




The HIP Trial is funded by the European Commission within the 7th Framework Programme
Practice in Czech Republic

• Tertiary units have someone who is able to perform
  neonatal Echo
• Close cooperation with cardiology and cardiac surgery
  (Cardiology center)
• Good prenatal diagnostics (lot of CHD recognized
  prenatally-delivery in the hospital with cardiology and
  cardiac surgery care)
• Self education, courses available




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
Summary

• Functional Echo – useful tool in circulatory status
  assessment
• Management can’t be based on Echo findings only
• Close cooperation with cardiologist necessary




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
Special thanks to Dr. Jachym Kucera




 The HIP Trial is funded by the European Commission within the 7th Framework Programme
Thank you for your attention




The HIP Trial is funded by the European Commission within the 7th Framework Programme

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Functional Neonatal Echocardiography in Haemodynamic Disturbancies

  • 1. Functional Neonatal Echocardiography in Haemodynamic Disturbancies Jana Semberova Institute for the Care of Mother and Child, Prague, Czech Republic The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 2. What can we see on echo when something goes wrong The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 3. Bedside neonatal echocardiography • Targeted neonatal echocardiography • Point of care echocardiography (POCT echo) • Functional echocardiography The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 4. WHY to perform the scan • Circulatory failure – major cause of neonatal morbidity and mortality • Measures currently used to assess circulatory status often inadequate • Circulation management varies widely • Lack of standardized approach • Echo can help to assess haemodynamic status and perhaps to guide treatment The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 5. WHEN to perform the scan? • Routine (e.g. PDA assesment) • Clinical status • Functional assessment – findings may change over time, sometimes very quickly The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 6. The role of functional Echo • Structure – exclude CHD • PDA • PPHN • Filling, contractility, flow • Other: Pericardial fluid, line position etc. The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 7. CHD - TOF The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 8. CHD - VSD The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 9. PDA – Left to Right The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 10. PDA - Bidirectional The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 11. PDA – flow pattern, pressure gradient The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 12. PDA heart failure The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 13. Pulmonary Hypertension The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 14. PPHN - TVI The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 15. Contractility assessment The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 16. Good Contractility The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 17. Poor Contractility The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 18. Hypertrophy The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 19. LVOTO The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 20. Filling (preload assessment – extracardiac IVC filling) The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 21. Pericardial fluid The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 22. Line position The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 23. Abdominal Aorta Flow Normal Finding Significant Left to Right Shunt - PDA Coarctation of the Aorta Low LV Output – Heart Failure The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 24. Other findings • Air embolia • Tumor • Thrombus • Etc…. The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 25. Functional assessment • Quantification and normative values • LVO, RVO – influenced by shunts • SVC flow, SF, EF • TDI, strain, strain rate, speckle tracking – not used routinely in neonates, more research tools • Visual assesment (Eyeballing) The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 26. The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 27. Management according to Echo findings ??? What to do with what we find • Fluid administration • Inotrope administration • Clinical status! • So far limited evidence of outcome improvement The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 28. Evolution over the time Day 1 Day 7 Day 38 The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 29. Evolution over the time FS 19% FS 36% The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 30. • CLOSE COOPERATION WITH PEDIATRIC CARDIOLOGIST CRUCIAL • Practice, recognition and availability of functional neonatal echo varies among countries/centers The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 31. TNE Guidelines The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 32. Practice in Czech Republic • Tertiary units have someone who is able to perform neonatal Echo • Close cooperation with cardiology and cardiac surgery (Cardiology center) • Good prenatal diagnostics (lot of CHD recognized prenatally-delivery in the hospital with cardiology and cardiac surgery care) • Self education, courses available The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 33. Summary • Functional Echo – useful tool in circulatory status assessment • Management can’t be based on Echo findings only • Close cooperation with cardiologist necessary The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 34. Special thanks to Dr. Jachym Kucera The HIP Trial is funded by the European Commission within the 7th Framework Programme
  • 35. Thank you for your attention The HIP Trial is funded by the European Commission within the 7th Framework Programme