Lifecare Centre Public Awareness Dr.Jyoti Bhaskar Anaemia Anaemia in Pregnancy Anaemia Treatment Iron Liberation Injectable IRON Therapy Facts about Anaemia Anaemia Management Anaemia Investigation Parental IRON Therapy

1. ANAEMIA FREE INIDIA

2. • Group photo
Our Team
PRESENTED At GYNAECON 10/10/2015
Our MISSION: SAY No TO ANAEMIA

3. DR. JYOTI BHASKAR
DR. SHARDA JAIN
Dr.Jyoti Aggarwal
SOARING HIGH !! THROUGH
IRON LIBERATION

4. Embarrassing !!

5. Indian Scenario

6. MAGNITUDE
• 49.7% of Indian pregnant women suffer
from anemia (WHO Global database, 2006)
20 % maternal deaths contributed by anemia
• Iron deficiency anemia (IDA) commonest cause of
anemia in pregnancy
Most Common deficiency state in the world
Preventable and correctable cause of anemia.
Dr. Sharda Jain – An activist and protagonist of Anaemia Free India –
80% pregnant women are Anaemic

7. Every Parent Aspires
That There Child will
Become another
APJ ABDUL KALAM

8. HARD FACT
HAEMOGLOBIN LEVELS AFFECTS
• INTELLIGENCE
• PERFORMACE
• Diminished
concentration
• Disturbance in
perception
• Poor learning
ability

9. Reduced Performance and Productivity
Decreased Work Output
Decreased Work Capacity

10. Anaemic Mother gives birth
to an Anaemic Baby
• Irregular Heavy menstruation
• Low pre-pregnancy iron stores
• LBW babies and preterm delivery

11. Hemorrhage
30%
Anemia
19%
Sepsis
16%
Abortion
9%
Obst. Lab
10%
Toxemia
8%
Others
8%
CAUSES OF MATERNAL MORTALITY
SRS-1998
- Direct cause of 20%of maternal deaths
Indirect cause for another 20% of maternal deaths
Nothing is more expensive than a missed opportunity!
UNCHANGED FOR 5 DECADES

12. Anaemia
Death
In India, over 300
maternal deaths
EVERYDAY,
about 200 due to anemia:
FOGSI
Beyond numbers!
For every maternal death, there are 30 more who ‘almost died’.

13. Definition
WHO defines Anemia as
•Hb< 12 gm/dl in women
•Hb< 13gm/dl in Men
•Anemia in pregnancy refer
Hb < 11gm/dl.

14. MANAGEMENT

15. DIET --- IRON AND PROTEINS

16. WHO
• Anthelminthic medication in pregnant women with
anaemia after 12 weeks of pregnancy
• Drug of choice is Mebendazole 100mg BD for 3 days
OR Albendazole 400mg

17. FERROUS SULPHATE
FERROUS GLUCOMATE
FERROUS FUMARATE
Ferrous Succinate

18. PARENTERAL IRON THERAPY
INDICATIONS
• Non compliance with, or intolerance to, oral iron therapy
• Proven malabsorption
• No Hemoglobinopathy
• Advanced gestation/post partum with moderate to severe
anemia

19. FORMULATIONS
• Low molecular weight Iron Dextran
• Iron Sucrose
• Ferric Carboxymaltose

20. Problems With Existing
Parenteral Iron Preparations
• The main disadvantage of Iron sucrose is the need for
multiple infusions as the maximum weekly dose should not
exceed 600 mg (200 mg IV, 1-3 times/week)
• Risk of anaphylaxis and allergic reactions
• Requirement of test dose administration
Cancado RD et al. Rev Bras Hematol Hemoter. 2011; 33(6): 461–469.

21. NEWER PREPARATIONS
Iron III carboxymaltose
(ferric hydroxide carbohydrate complex)
• Controlled delivery of iron within cells of reticuloendothelial
system (primarily bone marrow)
• Subsequent delivery to iron binding proteins ferritin and
transferrin.
• Rapid incorporation into RBCS

22. Dosage
• Single intravenous dose of 1000 mg over 15 minutes
(maximum 15 mg/kg by injection or 20 mg/kg by
infusion)
• Dilution:
• 500mg ferric carboxymaltose in 100mL sodium
chloride 0.9%.
• 1000mg ferric carboxymaltose in 250mL sodium
chloride 0.9%

23. • Flush with 50mL sodium chloride 0.9% before and
after iron infusion to minimise risk of extravasation.
• Maximum of 1000mg that can be given in one sitting.
• No test dose required

24. Indications
Were Parenteral iron is Indicated:
• Adolescents and All Women
• Pregnant women in 2nd – 3rd trimester
• Post-Partum Women
• Before Surgeries

25. Take Home Message
• We Need to Build an Anaemia free India
• Be Obsessed – Detection and Treatment
• Switch Over Early – to Parenteral Iron
• FCM – is Safe, Patient Friendly and
Effective

26. Iron strengthens!
Gold glittersSilver shines
But…

27. ISO 14001:2004 (EMS)
ISO 9001:2008
PLINE-9650588339/22414049
HELPLINE-9599044257
HELPLINE-9910081484
ISO 9001:2008
HELPLINE
9599044357
…..Caring hearts, healing hands