This research provides evidence that cravings are associated with individual patterns of arousal and are expressed differently in smokers and non-smokers. Patterns of physiologic arousal were identified for craving and tobacco use. This research supports the development of individual algorithms to predict tobacco use for tobacco cessation treatment.

1. The Psychophysiology of Tobacco Use and Craving Leigh W. Jerome, Ph.D. The Institute for Triple Helix Innovation Becky Rodericks, M.Sc. Pacific Telehealth & Technology Hui Funding provided by the USAMRMC (TATRC) (W81XWH-07-2-0086)

9. ● Current smokers, non-smokers, and former smokers ● Smokers : minimum of 10 cigarettes a day on average ● Former smokers : quit at least 6 months ago ● Self-described “good” health – no major medical conditions ● Not undergoing any form of nicotine replacement therapy ● Fluent in English ● 18 years + Eligibility

17. TIMESTAMP Sleep Cycles

19. In the last 10 years, Hawaii has gone from being ranked the number 1 healthiest state in the nation to the 9th healthiest state (Morgan Quitno, 2007). You will have 60 seconds to prepare a 3-minute speech explaining why you think this decline has taken place. “ 50% of the participants will be randomly selected to deliver their speech in front of a video camera (webcam). Your speech will be evaluated by the research team at a later date.” Elicited Stress Activity

21. Laboratory Setting Phase 3

23. Film clips: smoking scenes

28. Films eliciting fear

29. Films eliciting amusement

30. Neutral film clip images

37. BLOOD VOLUME PRESSURE (HRV)

38. SKIN TEMPERATURE

39. HEAT FLUX

41. RESPIRATION RATE

42. GALVANIC SKIN RESPONSE

44. Both deprived and non-deprived smokers reported similar levels of intensity after watching smoking clips; however deprived smokers were more likely to rate it an unpleasant experience (lower valence).

45. Following each of the four smoking clips, deprived smokers reported craving a cigarette more often than non-deprived smokers.

52. For information contact: [email_address]