Parathyroid

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Lara Patricia Catibog

Gesundheit & Medizin Technologie

PARATHYROID GLAND ,[object Object],[object Object],[object Object],[object Object],[object Object]

PARATHYROID GLANDS ,[object Object],[object Object],[object Object],[object Object],[object Object]

TYPE OF CELLS ,[object Object],[object Object]

CHIEF CELLS ,[object Object],[object Object],[object Object],[object Object],[object Object]

OXYPHIL CELLS ,[object Object],[object Object],[object Object],[object Object]

PARATHYROID HORMONE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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HISTOLOGY OF THYROID AND PARATHYROID GLAND Connective tissue component Parenchym atous component Parenchyma is made up of Thyroid follicles Parafollicular cells or C cells INACTIVE THYROID GLAND The follicles are lined by epithelial cell responsible for the synthesis of the glycoprotein component of thyroglobulin Conversion of iodide to iodine Thyroid epithelial cells are simple flat or cuboidal cells ACTIVE THYROID GLAND Active glands have more follicles and their epithelium is tall and columnar PARAFOLLICULAR OR C, CELL Parafollicular cells, derived from neural crest cells larger than follicular cells and Singly or in groups. Cells are polyhedral with oval eccentric nucleus

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The thyroid, or thyroid gland, is an endocrine gland in vertebrates. In humans, it is in the neck and consists of two connected lobes. The lower two thirds of the lobes are connected by a thin band of tissue called the isthmus. The thyroid gland is a butterfly-shaped gland located in the neck below the Adam's apple. Microscopically, the functional unit of the thyroid gland is the spherical thyroid follicle, lined with follicular cells (thyrocytes), and occasional parafollicular cells that surround a lumen containing colloid. The thyroid gland secretes three hormones: the two thyroid hormones – triiodothyronine (T3) and thyroxine (T4) – and a peptide hormone, calcitonin. The thyroid hormones influence the metabolic rate and protein synthesis and growth and development in children. Calcitonin plays a role in calcium homeostasis.[1] Secretion of the two thyroid hormones is regulated by thyroid-stimulating hormone (TSH), which is secreted from the anterior pituitary gland. TSH is regulated by thyrotropin-releasing hormone (TRH), which is produced by the hypothalamus.[2] Thyroid disorders include hyperthyroidism, hypothyroidism, thyroid inflammation (thyroiditis), thyroid enlargement (goitre), thyroid nodules, and thyroid cancer. Hyperthyroidism is characterized by excessive secretion of thyroid hormones: the most common cause is the autoimmune disorder Graves' disease. Hypothyroidism is characterized by a deficient secretion of thyroid hormones: the most common cause is iodine deficiency. In iodine-deficient regions, hypothyroidism secondary to iodine deficiency is the leading cause of preventable intellectual disability in children.[3] In iodine-sufficient regions, the most common cause of hypothyroidism is the autoimmune disorder Hashimoto's thyroiditis.

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