11. Survival Rate:
• Alive………………………………………....167 (41%)
• 5-Year Survivors…………..……………….101 (24.8%)
• 10-Year Survivors…………………………...53 (13%)
• Losses………………………………………215 (52.8%)
• General Life Span=1612.6 2070.5 days
• For 5-Year Survivors=4404.4 2543.9 days
• For 10-Year Survivors=6095.9 2468.3 days
• For Losses=691.1 389.5 days
• Cumulative 5-Year Survival………………..40%
• Cumulative 10-Year Survival………………32.7%
12. General Esophageal/Cardioesophageal Cancer Patients Survival
after Complete Esophagogastrectomies (Kaplan-Meier) (n=407)
Surv iv al Function
Ge ne ral Esophage al and Cardioe sophage al Cance r Patie nts Surv iv al afte r
Comple te Esophagogastre ctomie s, n=407
Cumulativ e 5-Ye ar Surv iv al=40%; 10-Ye ar surv iv al=32.7%
Complete Censored
1.2
Cumulative Proportion Surviving
1.1
1.0
0.9
0.8
0.7
0.6
0.5
0.4
0.3
0.2
0.1
0.0
-5 0 5 10 15 20 25 30 35 40
Ye ars afte r Esophagogastre ctomie s
13. Results of Univariate Analysis of Phase Transition Early—Invasive
Cancer in Prediction of Esophageal/Cardioesophageal Cancer
Patients Survival (n=407)
Cumulativ e Proportion Surv iv ing (Kaplan-M e ie r)
Cumulativ e 5-Ye ar Surv iv al of Early Cance r Patie nts=100%
Cumulativ e 5-Ye ar Surv iv al of Inv asiv e Cance r Patie nts=33.2%
P=0.000 by Log-Rank Te st
Complete Censored
1.0
Cumulative Proportion Surviving
0.8
0.6
Invasive Cancer Patients=364
0.4
Early Cancer Patients=43
0.2
0.0
-0.2
0 5 10 15 20 25 30 35 40
Ye ars afte r Esophagogastre ctomie s
14. Results of Univariate Analysis of Phase Transition N0—N1M1A in
Prediction of Esophageal/Cardioesophageal Cancer Patients
Survival (n=407)
Cumulativ e Proportion Surv iv ing (Kaplan-M e ie r)
Cumulativ e 5-Ye ar Surv iv al of Cance r Patie nts with N0=60.3%
Cumulativ e 5-Ye ar Surv iv al of Cance r Patie nts with N1-M 1A=25.1%
P=0.000 by Log-Rank Te st
Complete Censored
1.0
Cumulative Proportion Surviving
0.9
0.8
Cance r Patie nts with N0=167
Cance r Patie nts with N1-M 1A=240
0.7
0.6
0.5
0.4
0.3
0.2
0.1
0.0
0 5 10 15 20 25 30 35 40
Ye ars afte r Esophagogastre ctomie s
15. Results of Univariate Analysis of Adjuvant Therapy in Prediction of
Esophageal/Cardioesophageal Cancer Patients Survival (n=407)
Cumulative Proportion Surviving (Kaplan-Meier)
Complete Censored
5-Year Survival after Adjuvant Treatment=60.8%;
5-Year Survival after Surgery Along=36.4%;
P=0.00018 by Log-Rank Test
1.0
0.9
Cumulative Proportion Surviving
0.8
Adjuvant Treatment, n=83
0.7
Only Surgery, n=324
0.6
0.5
0.4
0.3
0.2
0.1
0.0
0 5 10 15 20 25 30 35 40
Years after Esophagogastrectomies
16. Results of Univariate Analysis of Tumor Localization in Prediction of
Esophageal/Cardioesophageal Cancer Patients Survival (n=407)
Cumulative Proportion Surviving (Kaplan-Meier)
Complete Censored
5-Year Survival of Esophageal Cancer Patients=49.1%;
5-Year Survival of Cardioesophageal Cancer Patients=34.4%;
P=0.003 by Log-Rank Test
1.0
0.9
Cumulative Proportion Surviving
0.8
0.7
Cardioesophageal Cancer Patients, n=272
0.6
Esophageal Cancer Patients, n=135
0.5
0.4
0.3
0.2
0.1
0.0
0 5 10 15 20 25 30 35 40
Years after Esophagogastrectomies
17. Results of Cox Regression Modeling in Prediction of
Esophageal/Cardioesophageal Cancer Patients Survival after Complete
Esophagogastrectomies (n=407)
18. Results of Neural Networks Computing in Prediction of
Esophageal/Cardioesophageal Cancer Patients Survival after Complete
Esophagogastrectomies (n=316)
19. Results of Bootstrap Simulation in Prediction of Esophageal Cancer
Patients Survival after Complete Esophagectomies (n=316)
21. Results of Kohonen Self-Organizing Neural Networks Computing in
Prediction of Esophageal/Cardioesophageal Cancer Patients
Survival after Complete Esophagogastrectomies (n=316)