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Presented by-
B.Pharm(3rd year)
Roland Institute Of Pharmaceutical Sciences
Berhampur, Odisha 1
2
Contents
I. Introduction
II. Materials & Method
III. AI in Field of Pharmacy
IV.Why AI in Pharma is a Good Idea ?
V. Imagine a Future where
VI.Investments in AI
VII.Results & Discussion
VIII.Top 10 AI Application that Could Change
Healthcare
IX.Steps of Usage of AI
X. Application of AI
XI.Scope for Further Research
XII.Recent AI Adoptions
XIII.Risks & Advantages Associated with AI
XIV.Conclusion And Future Perspectives 2
3
What is AI ?
3
4
Introduction
• According to Father of Artificial Intelligence(AI),John
McCarthy, it is ,“The science and engineering of
making intelligent machines“
• Artificial intelligence refers to the ability of a computer or
a computer enabled robotics system to process
information and produce outcomes in a manner similar
to the thought process of human in learning ,
decision making and solving problems.
• The goals of AI system is to develop system capable of
taking complex problems in ways similar to human
logic and reasoning.
5
Materials
and
Method
6
AI in field of Pharmacy
• It is one of the top technologies shaping the
future of pharmacy.
• Pharma industries has been developing cure &
treatment for centuries. Traditionally the design &
manufacturing of drug requires several years,
lengthy clinical trials & huge costs.
• With the rise of 21st century technologies, this has
been changing.
• In future we will see completely different drug
designs, manufacture & clinical trials.
7
Why AI in Pharma
is a good idea ?
• Pharmaceutical industry can accelerate innovation by using
technological advancements.
• The recent technological advancement that comes to mind would
be artificial advancement such as visual perception, speech
recognition, decision-making & translation between languages.
• An estimate by IBM shows that entire healthcare domain has
approx. 161 billion GB of data as of 2011.
• With humongous data available in this domain, AI can be of real
help in analysing the data & presenting results that would help out
in decision making, saving human effort,time,money & thus help
save lives
8
Imagine a Future where,
• AI is able to design new drugs
• Find new drug combination
• Deliver clinical trials within minutes
• Drugs are not tested on real humans or animals ,but on virtual
model that are engineered to mimic the physiology of organs.
• Robots help in the manufacturing of medication as well as
their distribution
• Counterfeiting drugs become almost impossible.
• Block-chain technology secures the entire distribution channel.
• Local pharmacists 3D prints personalised drugs in any shape &
desired dosage
9
Investments in AI
Last year, Verdict AI asked businesses how vital artificial
intelligence will be in their respective industries and over 70% of
them thought it would be very important. From the same
group, only 11% of businesses have not considered investing in AI
technology.
Furthermore, according to Narrative Science, 61% of companies
investing in innovative strategies are using AI to identify
opportunities that they would have otherwise missed. For
pharmaceutical businesses that thrive on innovation, this is an
important statistic to understand.
10
Results
and
Discussion
11
11
12
Stepsofusage
ofAI
13
Applications
of AI
13
14
• Disease Identification
• Radiology And Radiotherapy
• Clinical Trial Research
• Drug Discovery
• Personalized Medicine & Rare Disease
Identification
15
Disease Identification
Berg, an innovative US biopharma company, is
using AI to research and develop diagnostics
and therapeutics in the fields of oncology,
endocrinology, and neurology.
Their unique AI-based Interrogative Biology
platform combines patient biology and AI-based
analytics to identify differences between healthy
and disease environments.
16
Radiology & Radiotherapy
This is an area in which AI has been speculated to
play a major role in the future.
Presently, Google’s DeepMind Health is working
on machine learning algorithms to detect
differences between healthy and cancerous tissues.
The goal is to improve the accuracy of
radiotherapy planning while minimizing damage to
healthy organs at risk.
17
Clinical Trial Research
Advanced predictive analytics can analyze
genetic information to identify the appropriate
patient population for a trial.
Artificial Intelligence can also determine the
optimal sample sizes for increased efficiency
and reduce data errors such as duplicate
entries.
18
Drug Discovery
A study published by the Massachusetts Institute of
Technology (MIT) has found that only 13.8% of drugs
successfully pass clinical trials. Furthermore, a company
can expect to pay between $161 million to $2 billion for any
drug to complete the entire clinical trials process and get FDA
approval.
With this in mind, pharma businesses are using AI to increase
the success rates of new drugs while decreasing
operational costs at the same time.
Ideally, this would also translate to lower drug costs for
patients, all while offering them more treatment choices.
19
Personalized Medicine & Rare
Disease Identification
Using AI, body scans can detect cancer and other diseases early,
as well as predict health issues people might face based on their
genetics.
Although far from perfect, IBM Watson for Oncology is currently the
leader in AI for personalized treatment decisions in the oncology
space.It uses each patient’s medical information and history to
optimize the treatment decision-making. Recently, Watson correctly
diagnosed a rare form of leukemia in a patient originally thought to
have acute myeloid leukemia. It reportedly examined millions of
oncology research papers in 10 minutes after which it successfully
diagnosed the patient and recommended a personalized treatment
plan.
2020
21
Recent AI Adoptions
1. Novartis uses AI to predict untested components
researchers should explore to find new cures
2. IBM Watson helps match patients with the right
drug trials
3. Verge Genomics uses AI to predict the effect of
new treatments for patients suffering from ALS &
Alzheimer’s
4. Bayer and Merck & Co uses AI algorithms to
identify pulmonary hypertension 21
22
5. Tencent Holdings leverages AI to remotely monitor
patients with Parkinson’s
6. Mission Therapeutics uses AI to develop treatments
for Alzheimer’s
7. Healx uses AI to help biotech companies find
treatments for rare diseases
8. AiCure & AbbVie use image recognition to improve
drug adherence
9. Santen and twoXAR are using AI to develop drugs for
glaucoma 22
23
10.AstraZeneca and Alibaba build AI to help patients
with automated cancer diagnostics
11.Apple uses AI to screen children for autism
12.GNS Healthcare and Genentech use AI to develop
new cancer therapies
13.Deep 6 uses AI to proactively find drug trial
candidates
23
24
Risks & Disadvantage
Associated with AI
• As theoretical physicist Prof.Stephen Hawking had said that human
efforts to create machines that can think are a huge threat to the
existence of human race & the race to develop a complete human AI
could mean that the human race would come to an end in the future.
• High cost - creation of AI requires huge costs as they are very
complex machines
• Unemployment - AI can cause unemployment as things would be
automated in this system as there is need of less human labour
• No Match For Human Brain Intelligence
• No Improvement With Experience
• No Original Creativity
24
25
Conclusion
AI is doubtless the next big thing for pharma.
Companies that are more flexible and adopt AI faster
will likely gain a strategic advantage. In fact, experts
anticipate that implementing AI will soon be necessary
to compete in the industry.
However, the transformation will not happen overnight.
Instead, it will gradually occur over the next 10 or 20
years.
By then, AI is expected to be integrated into most, if
not all, pharma R&D operations. In turn, this should
theoretically improve the drug development success
rate and streamline R&D efforts.
26
REFERENCES
• https://becominghuman.ai/artificial-intelligence-in-pharma-4608b076a503
• https://www.ncbi.nlm.nih.gov/m/pubmed/10183640/
• https://www.digitalauthority.me/resources/artificial-intelligence-pharma/
• https://www.slideshare.net/SwastikJyoti/artificial-intelligence-ppt-
147888606?from_m_app=android
• https://www.youtube.com/themedicalfuturist
26
27
ACKNOWLEDGEMENT
I would like to express my special thanks of gratitude to
my teacher, my guide, my mentor
Mr. Deepak Sarangi
M.Pharm(Pharmaceutics)
Assistant Professor
Rips, Berhampur
who gave me the golden opportunity to do this wonderful
project on the topic "ARTIFICIAL INTELLIGENCE” which
also helped me in doing a lot of research.
I am really thankful to him.
27
28
Thank You

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Artificial intelligence in field of pharmacy

  • 1. 1 Presented by- B.Pharm(3rd year) Roland Institute Of Pharmaceutical Sciences Berhampur, Odisha 1
  • 2. 2 Contents I. Introduction II. Materials & Method III. AI in Field of Pharmacy IV.Why AI in Pharma is a Good Idea ? V. Imagine a Future where VI.Investments in AI VII.Results & Discussion VIII.Top 10 AI Application that Could Change Healthcare IX.Steps of Usage of AI X. Application of AI XI.Scope for Further Research XII.Recent AI Adoptions XIII.Risks & Advantages Associated with AI XIV.Conclusion And Future Perspectives 2
  • 4. 4 Introduction • According to Father of Artificial Intelligence(AI),John McCarthy, it is ,“The science and engineering of making intelligent machines“ • Artificial intelligence refers to the ability of a computer or a computer enabled robotics system to process information and produce outcomes in a manner similar to the thought process of human in learning , decision making and solving problems. • The goals of AI system is to develop system capable of taking complex problems in ways similar to human logic and reasoning.
  • 6. 6 AI in field of Pharmacy • It is one of the top technologies shaping the future of pharmacy. • Pharma industries has been developing cure & treatment for centuries. Traditionally the design & manufacturing of drug requires several years, lengthy clinical trials & huge costs. • With the rise of 21st century technologies, this has been changing. • In future we will see completely different drug designs, manufacture & clinical trials.
  • 7. 7 Why AI in Pharma is a good idea ? • Pharmaceutical industry can accelerate innovation by using technological advancements. • The recent technological advancement that comes to mind would be artificial advancement such as visual perception, speech recognition, decision-making & translation between languages. • An estimate by IBM shows that entire healthcare domain has approx. 161 billion GB of data as of 2011. • With humongous data available in this domain, AI can be of real help in analysing the data & presenting results that would help out in decision making, saving human effort,time,money & thus help save lives
  • 8. 8 Imagine a Future where, • AI is able to design new drugs • Find new drug combination • Deliver clinical trials within minutes • Drugs are not tested on real humans or animals ,but on virtual model that are engineered to mimic the physiology of organs. • Robots help in the manufacturing of medication as well as their distribution • Counterfeiting drugs become almost impossible. • Block-chain technology secures the entire distribution channel. • Local pharmacists 3D prints personalised drugs in any shape & desired dosage
  • 9. 9 Investments in AI Last year, Verdict AI asked businesses how vital artificial intelligence will be in their respective industries and over 70% of them thought it would be very important. From the same group, only 11% of businesses have not considered investing in AI technology. Furthermore, according to Narrative Science, 61% of companies investing in innovative strategies are using AI to identify opportunities that they would have otherwise missed. For pharmaceutical businesses that thrive on innovation, this is an important statistic to understand.
  • 11. 11 11
  • 14. 14 • Disease Identification • Radiology And Radiotherapy • Clinical Trial Research • Drug Discovery • Personalized Medicine & Rare Disease Identification
  • 15. 15 Disease Identification Berg, an innovative US biopharma company, is using AI to research and develop diagnostics and therapeutics in the fields of oncology, endocrinology, and neurology. Their unique AI-based Interrogative Biology platform combines patient biology and AI-based analytics to identify differences between healthy and disease environments.
  • 16. 16 Radiology & Radiotherapy This is an area in which AI has been speculated to play a major role in the future. Presently, Google’s DeepMind Health is working on machine learning algorithms to detect differences between healthy and cancerous tissues. The goal is to improve the accuracy of radiotherapy planning while minimizing damage to healthy organs at risk.
  • 17. 17 Clinical Trial Research Advanced predictive analytics can analyze genetic information to identify the appropriate patient population for a trial. Artificial Intelligence can also determine the optimal sample sizes for increased efficiency and reduce data errors such as duplicate entries.
  • 18. 18 Drug Discovery A study published by the Massachusetts Institute of Technology (MIT) has found that only 13.8% of drugs successfully pass clinical trials. Furthermore, a company can expect to pay between $161 million to $2 billion for any drug to complete the entire clinical trials process and get FDA approval. With this in mind, pharma businesses are using AI to increase the success rates of new drugs while decreasing operational costs at the same time. Ideally, this would also translate to lower drug costs for patients, all while offering them more treatment choices.
  • 19. 19 Personalized Medicine & Rare Disease Identification Using AI, body scans can detect cancer and other diseases early, as well as predict health issues people might face based on their genetics. Although far from perfect, IBM Watson for Oncology is currently the leader in AI for personalized treatment decisions in the oncology space.It uses each patient’s medical information and history to optimize the treatment decision-making. Recently, Watson correctly diagnosed a rare form of leukemia in a patient originally thought to have acute myeloid leukemia. It reportedly examined millions of oncology research papers in 10 minutes after which it successfully diagnosed the patient and recommended a personalized treatment plan.
  • 20. 2020
  • 21. 21 Recent AI Adoptions 1. Novartis uses AI to predict untested components researchers should explore to find new cures 2. IBM Watson helps match patients with the right drug trials 3. Verge Genomics uses AI to predict the effect of new treatments for patients suffering from ALS & Alzheimer’s 4. Bayer and Merck & Co uses AI algorithms to identify pulmonary hypertension 21
  • 22. 22 5. Tencent Holdings leverages AI to remotely monitor patients with Parkinson’s 6. Mission Therapeutics uses AI to develop treatments for Alzheimer’s 7. Healx uses AI to help biotech companies find treatments for rare diseases 8. AiCure & AbbVie use image recognition to improve drug adherence 9. Santen and twoXAR are using AI to develop drugs for glaucoma 22
  • 23. 23 10.AstraZeneca and Alibaba build AI to help patients with automated cancer diagnostics 11.Apple uses AI to screen children for autism 12.GNS Healthcare and Genentech use AI to develop new cancer therapies 13.Deep 6 uses AI to proactively find drug trial candidates 23
  • 24. 24 Risks & Disadvantage Associated with AI • As theoretical physicist Prof.Stephen Hawking had said that human efforts to create machines that can think are a huge threat to the existence of human race & the race to develop a complete human AI could mean that the human race would come to an end in the future. • High cost - creation of AI requires huge costs as they are very complex machines • Unemployment - AI can cause unemployment as things would be automated in this system as there is need of less human labour • No Match For Human Brain Intelligence • No Improvement With Experience • No Original Creativity 24
  • 25. 25 Conclusion AI is doubtless the next big thing for pharma. Companies that are more flexible and adopt AI faster will likely gain a strategic advantage. In fact, experts anticipate that implementing AI will soon be necessary to compete in the industry. However, the transformation will not happen overnight. Instead, it will gradually occur over the next 10 or 20 years. By then, AI is expected to be integrated into most, if not all, pharma R&D operations. In turn, this should theoretically improve the drug development success rate and streamline R&D efforts.
  • 26. 26 REFERENCES • https://becominghuman.ai/artificial-intelligence-in-pharma-4608b076a503 • https://www.ncbi.nlm.nih.gov/m/pubmed/10183640/ • https://www.digitalauthority.me/resources/artificial-intelligence-pharma/ • https://www.slideshare.net/SwastikJyoti/artificial-intelligence-ppt- 147888606?from_m_app=android • https://www.youtube.com/themedicalfuturist 26
  • 27. 27 ACKNOWLEDGEMENT I would like to express my special thanks of gratitude to my teacher, my guide, my mentor Mr. Deepak Sarangi M.Pharm(Pharmaceutics) Assistant Professor Rips, Berhampur who gave me the golden opportunity to do this wonderful project on the topic "ARTIFICIAL INTELLIGENCE” which also helped me in doing a lot of research. I am really thankful to him. 27