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MEDICATION ABUSE: Over-the-Counter & Prescription  Drug Abuse & Dependence Rand L. Kannenberg, M.A., LAC, CCM, CCS
Statistics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Marion Jones sentenced to 6 months for lying about steroids   Her attorney quoted the bard in asking a judge to be merciful, but the former Olympic track gold medalist was sentenced Friday to six months in prison for lying to investigators about using performance-enhancing drugs and about her role in a check-fraud scam.  Federal Judge Kenneth Karas imposed the maximum sentence suggested in Jones' plea deal, despite entreaties for a probation-only sentence from her and her lawyers.  http://sports.espn.go.com/espn/wire?id=3192894&section=oly Adam Butler/Associated Press
Ledger's Death: Sleeping Pills, Anti-Anxiety Drugs Found at Scene  Actor Heath Ledger, 28, was found dead at a Manhattan residence Tuesday. Police told ABC News' Richard Esposito that prescription drugs including sleeping pills and two anti-anxiety medications likely played a part, and the death appeared to be accidental.  http://abcnews.go.com/Nightline/Story?id=4173792&page=1 Djamilla Rosa Cochran/ WireImage
Teens and Prescription Drugs Advertisement: “Drug Dealer” Transcript 2.3.08  TRT 00:30  (Scene opens with a drug dealer outside of a convenience store walking on a sidewalk and approaches the camera.) Drug dealer:  “What’s this? What’s this? Documentary?  Man, right here, this is my business.”  (The drug dealer wanders up and down the sidewalk looking for potential customers and checks a pay phone for coins.) Drug dealer:  “Buying, selling, whatever, you know?  Slow!  Business is off, man.  Sales are down.  Seems like half my customers, they don’t even need me anymore, you know? I mean they’re getting high for free…Out of their medicine cabinets.”  (He throws up his arms and shakes his head in annoyance.) Drug dealer:  “How am I supposed to compete with that!?  You got kids?”   (Drug dealer points at the cameraman.) Cameraman:   “Yeah.” Drug dealer:  “Well, next time something goes south with your kids don’t look at me, man.  Ain’t my problem.  I didn’t do it.   (Laughs.)   I wish I did!” Narrator:  “Teens don’t need a drug dealer to get high.”   Text:  PARENTS.  THE ANTI-DRUG.  TheAntidrug.com 1-800-788-2800 Sponsored by Office of National Drug Control Policy/Partnership for a Drug-Free America® Narrator:  “Safeguard your prescriptions.  Safeguard your teens.”   Material provided by the Office of National Drug Control Policy
Teens and Prescription Drugs Advertisement: “All My Pills” Transcript 2.3.08  TRT 00:30 (Scene opens with a teenage boy sitting in a school cafeteria with a small tin box full of pills.) (The teenage boy holds up a yellow pill.) TEENAGE BOY:" This  yellow one is for my postpartum depression” (The teenage boy smirks, puts the yellow pill on the table then pulls a white pill out of the tin and holds it up.)  TEENAGE BOY:   “This one, sciatica, whatever that is” (The teenage boy puts the white pill on the table then pulls two blue pills out of the tin and holds them up.)  TEENAGE BOY:   “I got these after my hysterectomy, or my prostectomy or some ectomy” (The teenage boy puts the blue pills on the table then pulls a red pill out of the tin and holds it up.)  TEENAGE BOY:   “And this guy is for the pain from my last hip replacement.” (The teenage boy puts the red pill on the table then pulls an orange pill out of the tin and holds it up.)  TEENAGE BOY:   “And this orange one is…” (The lunch bell rings and the teenage boy scoops his pills off the table and back into the tin)  TEENAGE BOY:   “Gotta go” NARRATOR:   “For teens, getting drugs can be as easy as opening your medicine cabinet.” (The screen goes black.) Text:  PARENTS.  THE ANTI-DRUG.  TheAntidrug.com 1-800-788-2800 Sponsored by Office of National Drug Control Policy/Partnership for a Drug-Free America® Material provided by the Office of National Drug Control Policy
Objectives ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],At the end of this seminar the participant will be able to:
Agenda & Outline ,[object Object],[object Object],[object Object],[object Object]
Schedule II. (A) The drug or other substance has a  high potential for abuse .  (B) The drug or other substance has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions.  (C) Abuse of the drug or other substances may lead to  severe psychological or physical dependence . Schedule III. (A) The drug or other substance has a potential for abuse less than the drugs or other substances in schedules I and II.  (B) The drug or other substance has a currently accepted medical use in treatment in the United States.  (C) Abuse of the drug or other substance may lead to moderate or low physical dependence or high psychological dependence. Schedule IV. (A) The drug or other substance has a low potential for abuse relative to the drugs or other substances in schedule III.  (B) The drug or other substance has a currently accepted medical use in treatment in the United States.  (C) Abuse of the drug or other substance may lead to limited physical dependence or psychological dependence relative to the drugs or other substances in schedule III. Schedule V. (A) The drug or other substance has a  low potential for abuse  relative to the drugs or other substances in schedule IV.  (B) The drug or other substance has a currently accepted medical use in treatment in the United States.  (C) Abuse of the drug or other substance may lead to  limited physical dependence or psychological dependence  relative to the drugs or other substances in schedule IV. Schedules of controlled substances
Opioids  & morphine derivatives       hydrocodone (Schedules II, III, V)   Examples  Hydrocodone with Acetaminophen,  Vicodin ® , Vicoprofen®, Tussionex®, Lortab®, Tussend®, Hycodan®, Anexsia® Nicknames vike, Watson-387  Route of Administration swallowed Desired Outcomes pain relief, euphoria Adverse Reactions drowsiness, nausea, constipation, confusion, sedation, respiratory arrest,  unconsciousness, coma, constricted pupils, slow and shallow breathing, clammy skin, convulsions, possible death  OPI “ Opiates” “ Narcotic Analgesics” “ Pain Killers” Schedule of Substance Schedule of Products Oral (swallow) Intranasal (snort) Injection (IV,IM,SUB Q) Inhalation (smoke)
Opioids  & morphine derivatives       oxycodone (Schedule II)   Examples Roxicet®, Oxycodone with Acetaminophen,  OxyContin ® , Endocet®,  Percocet ® , Percodan®, Tylox®, Roxicodone® Nicknames Oxy, O.C., killer  Route of Administration swallowed, snorted, injected  Desired Outcomes pain relief, euphoria Adverse Reactions drowsiness, nausea, constipation, confusion, sedation, respiratory arrest, unconsciousness, coma, constricted pupils, slow and shallow breathing, clammy skin, convulsions, possible death   (Time Release Tablet)
Opioids  & morphine derivatives     ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Barbiturate/Opioid
Opioids  & morphine derivatives       morphine (Schedules II, III) Examples Duramorph®,  MS-Contin ® , Roxanol®, Oramorph SR®, RMS®  Nicknames M, Miss Emma, monkey, white stuff  Route of Administration injected, swallowed, smoked  Desired Outcomes pain relief, euphoria  Adverse Reactions drowsiness, nausea, constipation, confusion, sedation, respiratory arrest, unconsciousness, coma, constricted pupils,  slow and shallow breathing, clammy skin, convulsions, possible death
Opioids  & morphine derivatives       hydro-morphone (Schedule II)   Examples Dilaudid ® , dihydromorphinone  Nicknames Dust, Juice, Smack, D, Footballs  Route of Administration swallowed, injected Desired Outcomes pain relief, euphoria  Adverse Reactions drowsiness, nausea, constipation, confusion, sedation, respiratory arrest, unconsciousness, coma, constricted pupils,  slow and shallow breathing, clammy skin, convulsions, possible death
Opioids  & morphine derivatives       opium (Schedules II, III, V) Examples laudanum, paregoric, papaver somniferum, extracts/fluid/poppy/tincture/granulated/powdered/raw, Parepectolin®, Kapectolin PG®, Kaolin®, Pectin P.G.® Nicknames big O, black stuff, block, gum, hop  Route of Administration swallowed, smoked  Desired Outcomes pain relief, euphoria  Adverse Reactions drowsiness, nausea, constipation, confusion, sedation, respiratory arrest, unconsciousness, coma, constricted pupils,  slow and shallow breathing, clammy skin, convulsions, possible death   Also used for diarrhea & cough.
Opioids  & morphine derivatives       other narcotics (Schedules II, III, IV) Examples Actiq ® ,  Duragesic ® , Sublimaze®,  Fentanyl ® , Demerol®, methadone, Darvon®, Darvocet®, Stadol®, Talwin®, Paregoric®, Buprenex®, propoxyphene, Propacet®, Innovar®, Mepergan®, pethidine Nicknames Apache, China girl, China white, dance fever, friend, goodfella, jackpot, murder 8, TNT, Tango and Cash  Route of Administration swallowed, injected, smoked, snorted  Desired Outcomes pain relief, euphoria  Adverse Reactions drowsiness, nausea, constipation, confusion, sedation, respiratory arrest, unconsciousness, coma, constricted pupils,  slow and shallow breathing, clammy skin, convulsions, possible death  Lollipop Patch Not  detected in immunoassays. Lozenge   on plastic stick between cheeks and gums in mouth. Suck on it, twirl it. Only for breakthrough cancer pain if 16 or older. 80 x stronger than morphine! In its own class.   IV/IM
Video #1 “Opioids” (3 minutes & 8 seconds)
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],May require sleep study for continuous  positive airway pressure (CPAP) device at bedtime with fan, tubes and mask.
CNS depressants     barbiturates (Schedules II, III, IV) Examples (methohexital) Brevital®, (thiamyl) Surital®, (thiopental) Pentothal®, (amobarbital) Amyta®, (pentobarbital) Nembutal®, (secobarbital)  Seconal ® , (amobarbital/secobarbital) Tuinal®, (butalbital) Fiorina®, (butabarbital) Butisol®, (talbutal) Lotusate®, (aprobarbital) Alurate®, ( phenobarbital ) Luminal®, (mephobarbital) Mebaral® Nicknames barbs, reds, red birds, phennies, tooies, yellows, yellow jackets  Route of Administration injected, swallowed  Desired Outcomes reduced pain and anxiety; feeling of well-being; lowered inhibitions  Adverse Reactions slowed pulse and breathing, lowered blood pressure, poor concentration/fatigue, confusion, impaired coordination/memory/judgment,  respiratory depression and arrest, death, sedation, drowsiness/depression, unusual excitement, fever, irritability, poor judgment, slurred speech, dizziness, life-threatening withdrawal BAR “ Sedatives” “ Hypnotics” “ Anxiolytics” Used for mild sedation to surgical anesthesia. Also used for pain (e.g.,  tension headaches) or  as anticonvulsants. Used less often for sleep/anxiety because more lethal if OD. Used in euthanasia with most animals, as well as human executions  and assisted suicides (usually with muscle relaxant and potassium). Fiorecet ®  has Tylenol ®/ caffeine.
CNS depressants   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BZO or BZD Sleep Antianxiety  Alcohol withdrawal NOT Ambien ® or Lunesta®.
CNS depressants   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],“ Date Rape Drug” Schedule IV, but illegal in the U.S. since 1996 because “Drug Induced Rape Prevention and Punishment Act.”  Schedule III by WHO 1995. GHB is Schedule I.
Video #2 “Benzos”   (2 minutes & 46 seconds)
Dissociative anesthetics   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Also known as a date rape drug. Used primarily by veterinarians.
Stimulants ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],AMP
Stimulants cocaine (Schedule  II ) Examples Cocaine hydrochloride  Nicknames blow, bump, C, candy, Charlie, coke,  crack , flake, rock, snow, toot  Route of Administration swallowed, snorted, injected,  smoked Desired Outcomes awake, alert, active, aware, appetite suppression, energy, euphoria, excitement, enthusiasm, enhancement of the senses Adverse Reactions dysphoric crash, death from respiratory failure, strokes, heart failure, increased heart rate, high blood pressure, increased metabolism, irregular heart beat, weight loss, nervousness, insomnia, increased temperature, chest pain, nausea, abdominal pain, seizures, headaches, malnutrition, panic attacks COC Used in eye, ear, nose and throat surgeries.
methamphetamine (Schedule  II ) Example Desoxyn® Nicknames chalk, crank, crystal, fire, glass, go fast,  ice , meth, speed  Route of Administration swallowed, snorted, injected,  smoked Desired Outcomes awake, alert, active, aware, appetite suppression, energy, euphoria, excitement, enthusiasm,  enhancement of the senses Adverse Reactions inability to sleep, loss of appetite and weight, thin/gaunt, increased sensitivity to noise, agitation, restlessness, irritability, aggressiveness, dizziness, confusion, impaired judgment, diarrhea and gastrointestinal complaints, difficulty breathing, headaches, tremors or seizures, nausea and vomiting, numbness, profuse sweating, chills, muscle cramping, pain and tenderness, dehydration, low magnesium level, low potassium level, grossly dilated pupils, chest pain, increased or decreased heart rate, increased blood pressure, fever or hyperthermia, impaired speech and language, mania, psychosis with hallucinations and delusions, anxiety, panic, fear of impending doom, depression and suicidal ideation, poor hygiene and body malodor, missing teeth, bleeding gums, infected gums, dental caries/decay/cavities, dry mouth, removed enamel, teeth grinding, skin aging and damage, dryness, roughness, wrinkles, broken veins, dermatitis around the mouth, skin ulceration and infection, acne or sores, hair loss from repetitious pulling MA Dextro-Levo-Methamphetamine,  aka, D-Methamphetamine. Vicks ®  Vapor Inhaler is Levo-Methamphetamine. All these symptoms increased if made illegally in U.S., Mexico or Asia.
Stimulants methylphenidate (Schedule II) Examples Ritalin ® , Methylin®,  Concerta ® Nicknames JIF, MPH, R-ball, Skippy, the smart drug, vitamin R  Route of Administration swallowed, snorted, injected Desired Outcomes awake, alert, active, aware, appetite suppression, energy, euphoria, excitement, enthusiasm, enhancement of the senses Adverse Reactions increased heart rate, high blood pressure, increased metabolism, irregular heart beat, weight loss, heart failure, nervousness, insomnia   Cylert ® (pemoline) discontinued by Abbott Laboratories in 2005 (liver studies). Strattera ® (atomexetine HCI) is a non stimulant.
Anabolic steroids (Schedule III) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Taking multiple doses over time. Combining different types at once. Slowly escalating dose/reaching a peak/then tapering dose. (Male sex hormone) NOT Corticosteroids (e.g.,  Cortisone/Prednisone). For allergy, breathing, pain, skin problems.
Dextromethorphan  ( DXM ) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],More than 125 OTC cold, cough, allergy, sinus, and hay fever medications. Anyone with debit/ credit card can buy online at all major  U.S. pharmacies. Kids/teens/adults may take entire box/bottle or more!
Video #3 “DXM”   (1minute & 50 seconds)
Weight loss pills Examples bitter orange, chitosan, chromium, conjugated linoleic acid (CLA), county mallow (heartleaf),  ephedra ,  green tea extract , guar gum,  hoodia Nicknames same as above Route of Administration swallowed Desired Outcomes decrease appetite, block absorption of dietary fat, reduce fat, build muscle, increase calorie and fat metabolism, increase the feeling of fullness Adverse Reactions constipation, bloating, diarrhea, indigestion, high blood pressure, heart rate irregularities, sleeplessness, seizures, heart attacks, strokes, death, vomiting, flatulence
Sleeping aids ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Also Tylenol ®  PM. Motion sickness. Antihistamines.
Online or e-pharmacies  fax broadcasting/blasting ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],All require a prescription.  Only  Fioricet ®  is controlled.  Ultram ®  (tramadol) (opioid-like) and Soma  (muscle relaxant) are abused.
Minors ordering on the Internet ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
“ Pill mills” ,[object Object],[object Object],[object Object]
Street use ,[object Object],[object Object]
  Identifying Drug-Seeking  Patients ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Case Study 1 ,[object Object],[object Object],[object Object]
Case Study 2 ,[object Object],[object Object],[object Object],[object Object],[object Object]
“ Opiophobia”   ,[object Object]
Characteristics of overprescribing physicians ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
How to approach physicians with concerns ,[object Object],[object Object],[object Object],[object Object],[object Object]
Types of drug testing ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],NOT reliable unless unannounced, unscheduled and observed.
Detection periods ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],(i.e., NOT street MA or street COC)
Alternatives to controlled drugs for anxiety ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],(e.g., Toprol ®  XL,  Lopressor ® ).
Alternatives to controlled drugs for insomnia ,[object Object]
Alternatives to controlled drugs for ADHD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],(aka, “SSRI”) (e.g., Paxil ® , Zoloft ® , Prozac ® , Lexapro ® , etc.) Strattera® (atomexetine HCI) is a non stimulant.
Alternatives to controlled drugs for pain ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],(i.e., aspirin, ibuprofen) (corticosteroids) (e.g., Soma ® , Flexeril ®)
Suboxone® versus Methadone or LAAM ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Guidelines for Writing Prescriptions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
“ Clinical Sobriety Checklist” (CSC)™ for medications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
_____legal, illegal, prescription and over-the-counter substance(s) used;  _____amount/route of administration/frequency/duration of use;  _____when started using; _____why using/used;  _____last use; _____blood alcohol level and time;  _____breath test result and time;  _____urine drug screen results and time;  _____CIWA score and time;  _____COWS score and time;  _____CAGE score; Prescription drug interview questions
_____history of blackouts;  _____history of intoxication or withdrawal delirium;  _____history of intoxication or withdrawal seizures;  _____history of substance induced psychosis, mania, anxiety or depression;  _____longest time clean/sober,  _____history of addiction treatment;  _____history of addiction support;  _____history of addiction education;  _____history of substance related legal problems;  _____history of physical problems as a result of using; and _____problems at home, work or school as a result of using.
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Drug addiction test ,[object Object],[object Object],[object Object]
Substance dependence screening ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Substance abuse screening ,[object Object],[object Object],[object Object],[object Object],[object Object],No such thing as Polysubstance Abuse.
Benzodiazepine withdrawal symptom questionnaire ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Each moderate score is given a rating of 1 and each severe score a rating of 2. The maximum score possible is 40, unless of course additional symptoms are included.  Note also whether the symptoms occurred when the tablets were reduced or stopped, or if the symptoms occurred when the tablets were the same.  If the individual attains an overall score above 20 seek specialist medical help.  If the individual endorses a number of severe symptoms seek specialist medical help.  If the individual reports a number of new symptoms seek specialist medical help. May result in death!
  For each item, write in the number that best describes the patient’s signs or symptom.  Rate on just the apparent relationship to opiate withdrawal.  For example, if heart rate is increased because the patient was jogging just prior to assessment, the increase pulse rate would not add to the score.   Clinical Opiate  Withdrawal Scale  (COWS) .   Patient’s Name:___________________________                          Date: ______________
Resting Pulse Rate:  (record beats per minute)                     Measured after patient is sitting or lying for one minute. 0 pulse rate 80 or below 1 pulse rate 81-100 2 pulse rate 101-120 4 pulse rate greater than 120 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
      Score:  5-12 = mild;  13-24 = moderate;  25-36 = moderately severe; more than 36 = severe withdrawal                                   Total scores   with observer’s initials
Adult Inpatient Medical Detoxification   Admission Criteria Checklist ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],e.g., psychotic, manic,  depressed, anxious, etc.
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Adult Inpatient Medical  Detoxification   Admission Criteria Checklist
Adult Inpatient Medical Detoxification   Admission Criteria Checklist ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
TECHNIQUES USING (CLONIDINE) CATAPRES® FOR OPIATES ,[object Object],[object Object],[object Object],[object Object],[object Object]
TECHNIQUES USING (DIAZEPAM) VALIUM® OR (CLONAZEPAM) KLONOPIN® FOR ANXIOLYTICS, SEDATIVES, HYPNOTICS ,[object Object],[object Object],[object Object]
Rapid detoxification ,[object Object],[object Object]
The “4 Ds” of  quitting medications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 

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Medication Abuse by Rand L. Kannenberg

  • 1. MEDICATION ABUSE: Over-the-Counter & Prescription Drug Abuse & Dependence Rand L. Kannenberg, M.A., LAC, CCM, CCS
  • 2.
  • 3. Marion Jones sentenced to 6 months for lying about steroids Her attorney quoted the bard in asking a judge to be merciful, but the former Olympic track gold medalist was sentenced Friday to six months in prison for lying to investigators about using performance-enhancing drugs and about her role in a check-fraud scam. Federal Judge Kenneth Karas imposed the maximum sentence suggested in Jones' plea deal, despite entreaties for a probation-only sentence from her and her lawyers. http://sports.espn.go.com/espn/wire?id=3192894&section=oly Adam Butler/Associated Press
  • 4. Ledger's Death: Sleeping Pills, Anti-Anxiety Drugs Found at Scene Actor Heath Ledger, 28, was found dead at a Manhattan residence Tuesday. Police told ABC News' Richard Esposito that prescription drugs including sleeping pills and two anti-anxiety medications likely played a part, and the death appeared to be accidental. http://abcnews.go.com/Nightline/Story?id=4173792&page=1 Djamilla Rosa Cochran/ WireImage
  • 5. Teens and Prescription Drugs Advertisement: “Drug Dealer” Transcript 2.3.08  TRT 00:30 (Scene opens with a drug dealer outside of a convenience store walking on a sidewalk and approaches the camera.) Drug dealer: “What’s this? What’s this? Documentary?  Man, right here, this is my business.” (The drug dealer wanders up and down the sidewalk looking for potential customers and checks a pay phone for coins.) Drug dealer: “Buying, selling, whatever, you know?  Slow!  Business is off, man.  Sales are down.  Seems like half my customers, they don’t even need me anymore, you know? I mean they’re getting high for free…Out of their medicine cabinets.” (He throws up his arms and shakes his head in annoyance.) Drug dealer: “How am I supposed to compete with that!?  You got kids?”  (Drug dealer points at the cameraman.) Cameraman:   “Yeah.” Drug dealer: “Well, next time something goes south with your kids don’t look at me, man.  Ain’t my problem.  I didn’t do it.  (Laughs.)   I wish I did!” Narrator: “Teens don’t need a drug dealer to get high.”  Text: PARENTS.  THE ANTI-DRUG.  TheAntidrug.com 1-800-788-2800 Sponsored by Office of National Drug Control Policy/Partnership for a Drug-Free America® Narrator: “Safeguard your prescriptions.  Safeguard your teens.”   Material provided by the Office of National Drug Control Policy
  • 6. Teens and Prescription Drugs Advertisement: “All My Pills” Transcript 2.3.08  TRT 00:30 (Scene opens with a teenage boy sitting in a school cafeteria with a small tin box full of pills.) (The teenage boy holds up a yellow pill.) TEENAGE BOY:" This yellow one is for my postpartum depression” (The teenage boy smirks, puts the yellow pill on the table then pulls a white pill out of the tin and holds it up.) TEENAGE BOY: “This one, sciatica, whatever that is” (The teenage boy puts the white pill on the table then pulls two blue pills out of the tin and holds them up.) TEENAGE BOY: “I got these after my hysterectomy, or my prostectomy or some ectomy” (The teenage boy puts the blue pills on the table then pulls a red pill out of the tin and holds it up.) TEENAGE BOY: “And this guy is for the pain from my last hip replacement.” (The teenage boy puts the red pill on the table then pulls an orange pill out of the tin and holds it up.) TEENAGE BOY: “And this orange one is…” (The lunch bell rings and the teenage boy scoops his pills off the table and back into the tin) TEENAGE BOY: “Gotta go” NARRATOR: “For teens, getting drugs can be as easy as opening your medicine cabinet.” (The screen goes black.) Text: PARENTS.  THE ANTI-DRUG.  TheAntidrug.com 1-800-788-2800 Sponsored by Office of National Drug Control Policy/Partnership for a Drug-Free America® Material provided by the Office of National Drug Control Policy
  • 7.
  • 8.
  • 9. Schedule II. (A) The drug or other substance has a high potential for abuse . (B) The drug or other substance has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. (C) Abuse of the drug or other substances may lead to severe psychological or physical dependence . Schedule III. (A) The drug or other substance has a potential for abuse less than the drugs or other substances in schedules I and II. (B) The drug or other substance has a currently accepted medical use in treatment in the United States. (C) Abuse of the drug or other substance may lead to moderate or low physical dependence or high psychological dependence. Schedule IV. (A) The drug or other substance has a low potential for abuse relative to the drugs or other substances in schedule III. (B) The drug or other substance has a currently accepted medical use in treatment in the United States. (C) Abuse of the drug or other substance may lead to limited physical dependence or psychological dependence relative to the drugs or other substances in schedule III. Schedule V. (A) The drug or other substance has a low potential for abuse relative to the drugs or other substances in schedule IV. (B) The drug or other substance has a currently accepted medical use in treatment in the United States. (C) Abuse of the drug or other substance may lead to limited physical dependence or psychological dependence relative to the drugs or other substances in schedule IV. Schedules of controlled substances
  • 10. Opioids & morphine derivatives hydrocodone (Schedules II, III, V) Examples Hydrocodone with Acetaminophen, Vicodin ® , Vicoprofen®, Tussionex®, Lortab®, Tussend®, Hycodan®, Anexsia® Nicknames vike, Watson-387 Route of Administration swallowed Desired Outcomes pain relief, euphoria Adverse Reactions drowsiness, nausea, constipation, confusion, sedation, respiratory arrest, unconsciousness, coma, constricted pupils, slow and shallow breathing, clammy skin, convulsions, possible death OPI “ Opiates” “ Narcotic Analgesics” “ Pain Killers” Schedule of Substance Schedule of Products Oral (swallow) Intranasal (snort) Injection (IV,IM,SUB Q) Inhalation (smoke)
  • 11. Opioids & morphine derivatives oxycodone (Schedule II) Examples Roxicet®, Oxycodone with Acetaminophen, OxyContin ® , Endocet®, Percocet ® , Percodan®, Tylox®, Roxicodone® Nicknames Oxy, O.C., killer Route of Administration swallowed, snorted, injected Desired Outcomes pain relief, euphoria Adverse Reactions drowsiness, nausea, constipation, confusion, sedation, respiratory arrest, unconsciousness, coma, constricted pupils, slow and shallow breathing, clammy skin, convulsions, possible death (Time Release Tablet)
  • 12.
  • 13. Opioids & morphine derivatives morphine (Schedules II, III) Examples Duramorph®, MS-Contin ® , Roxanol®, Oramorph SR®, RMS® Nicknames M, Miss Emma, monkey, white stuff Route of Administration injected, swallowed, smoked Desired Outcomes pain relief, euphoria Adverse Reactions drowsiness, nausea, constipation, confusion, sedation, respiratory arrest, unconsciousness, coma, constricted pupils, slow and shallow breathing, clammy skin, convulsions, possible death
  • 14. Opioids & morphine derivatives hydro-morphone (Schedule II) Examples Dilaudid ® , dihydromorphinone Nicknames Dust, Juice, Smack, D, Footballs Route of Administration swallowed, injected Desired Outcomes pain relief, euphoria Adverse Reactions drowsiness, nausea, constipation, confusion, sedation, respiratory arrest, unconsciousness, coma, constricted pupils, slow and shallow breathing, clammy skin, convulsions, possible death
  • 15. Opioids & morphine derivatives opium (Schedules II, III, V) Examples laudanum, paregoric, papaver somniferum, extracts/fluid/poppy/tincture/granulated/powdered/raw, Parepectolin®, Kapectolin PG®, Kaolin®, Pectin P.G.® Nicknames big O, black stuff, block, gum, hop Route of Administration swallowed, smoked Desired Outcomes pain relief, euphoria Adverse Reactions drowsiness, nausea, constipation, confusion, sedation, respiratory arrest, unconsciousness, coma, constricted pupils, slow and shallow breathing, clammy skin, convulsions, possible death Also used for diarrhea & cough.
  • 16. Opioids & morphine derivatives other narcotics (Schedules II, III, IV) Examples Actiq ® , Duragesic ® , Sublimaze®, Fentanyl ® , Demerol®, methadone, Darvon®, Darvocet®, Stadol®, Talwin®, Paregoric®, Buprenex®, propoxyphene, Propacet®, Innovar®, Mepergan®, pethidine Nicknames Apache, China girl, China white, dance fever, friend, goodfella, jackpot, murder 8, TNT, Tango and Cash Route of Administration swallowed, injected, smoked, snorted Desired Outcomes pain relief, euphoria Adverse Reactions drowsiness, nausea, constipation, confusion, sedation, respiratory arrest, unconsciousness, coma, constricted pupils, slow and shallow breathing, clammy skin, convulsions, possible death Lollipop Patch Not detected in immunoassays. Lozenge on plastic stick between cheeks and gums in mouth. Suck on it, twirl it. Only for breakthrough cancer pain if 16 or older. 80 x stronger than morphine! In its own class. IV/IM
  • 17. Video #1 “Opioids” (3 minutes & 8 seconds)
  • 18.
  • 19. CNS depressants barbiturates (Schedules II, III, IV) Examples (methohexital) Brevital®, (thiamyl) Surital®, (thiopental) Pentothal®, (amobarbital) Amyta®, (pentobarbital) Nembutal®, (secobarbital) Seconal ® , (amobarbital/secobarbital) Tuinal®, (butalbital) Fiorina®, (butabarbital) Butisol®, (talbutal) Lotusate®, (aprobarbital) Alurate®, ( phenobarbital ) Luminal®, (mephobarbital) Mebaral® Nicknames barbs, reds, red birds, phennies, tooies, yellows, yellow jackets Route of Administration injected, swallowed Desired Outcomes reduced pain and anxiety; feeling of well-being; lowered inhibitions Adverse Reactions slowed pulse and breathing, lowered blood pressure, poor concentration/fatigue, confusion, impaired coordination/memory/judgment, respiratory depression and arrest, death, sedation, drowsiness/depression, unusual excitement, fever, irritability, poor judgment, slurred speech, dizziness, life-threatening withdrawal BAR “ Sedatives” “ Hypnotics” “ Anxiolytics” Used for mild sedation to surgical anesthesia. Also used for pain (e.g., tension headaches) or as anticonvulsants. Used less often for sleep/anxiety because more lethal if OD. Used in euthanasia with most animals, as well as human executions and assisted suicides (usually with muscle relaxant and potassium). Fiorecet ® has Tylenol ®/ caffeine.
  • 20.
  • 21.
  • 22. Video #2 “Benzos” (2 minutes & 46 seconds)
  • 23.
  • 24.
  • 25. Stimulants cocaine (Schedule II ) Examples Cocaine hydrochloride Nicknames blow, bump, C, candy, Charlie, coke, crack , flake, rock, snow, toot Route of Administration swallowed, snorted, injected, smoked Desired Outcomes awake, alert, active, aware, appetite suppression, energy, euphoria, excitement, enthusiasm, enhancement of the senses Adverse Reactions dysphoric crash, death from respiratory failure, strokes, heart failure, increased heart rate, high blood pressure, increased metabolism, irregular heart beat, weight loss, nervousness, insomnia, increased temperature, chest pain, nausea, abdominal pain, seizures, headaches, malnutrition, panic attacks COC Used in eye, ear, nose and throat surgeries.
  • 26. methamphetamine (Schedule II ) Example Desoxyn® Nicknames chalk, crank, crystal, fire, glass, go fast, ice , meth, speed Route of Administration swallowed, snorted, injected, smoked Desired Outcomes awake, alert, active, aware, appetite suppression, energy, euphoria, excitement, enthusiasm, enhancement of the senses Adverse Reactions inability to sleep, loss of appetite and weight, thin/gaunt, increased sensitivity to noise, agitation, restlessness, irritability, aggressiveness, dizziness, confusion, impaired judgment, diarrhea and gastrointestinal complaints, difficulty breathing, headaches, tremors or seizures, nausea and vomiting, numbness, profuse sweating, chills, muscle cramping, pain and tenderness, dehydration, low magnesium level, low potassium level, grossly dilated pupils, chest pain, increased or decreased heart rate, increased blood pressure, fever or hyperthermia, impaired speech and language, mania, psychosis with hallucinations and delusions, anxiety, panic, fear of impending doom, depression and suicidal ideation, poor hygiene and body malodor, missing teeth, bleeding gums, infected gums, dental caries/decay/cavities, dry mouth, removed enamel, teeth grinding, skin aging and damage, dryness, roughness, wrinkles, broken veins, dermatitis around the mouth, skin ulceration and infection, acne or sores, hair loss from repetitious pulling MA Dextro-Levo-Methamphetamine, aka, D-Methamphetamine. Vicks ® Vapor Inhaler is Levo-Methamphetamine. All these symptoms increased if made illegally in U.S., Mexico or Asia.
  • 27. Stimulants methylphenidate (Schedule II) Examples Ritalin ® , Methylin®, Concerta ® Nicknames JIF, MPH, R-ball, Skippy, the smart drug, vitamin R Route of Administration swallowed, snorted, injected Desired Outcomes awake, alert, active, aware, appetite suppression, energy, euphoria, excitement, enthusiasm, enhancement of the senses Adverse Reactions increased heart rate, high blood pressure, increased metabolism, irregular heart beat, weight loss, heart failure, nervousness, insomnia Cylert ® (pemoline) discontinued by Abbott Laboratories in 2005 (liver studies). Strattera ® (atomexetine HCI) is a non stimulant.
  • 28.
  • 29.
  • 30. Video #3 “DXM” (1minute & 50 seconds)
  • 31. Weight loss pills Examples bitter orange, chitosan, chromium, conjugated linoleic acid (CLA), county mallow (heartleaf), ephedra , green tea extract , guar gum, hoodia Nicknames same as above Route of Administration swallowed Desired Outcomes decrease appetite, block absorption of dietary fat, reduce fat, build muscle, increase calorie and fat metabolism, increase the feeling of fullness Adverse Reactions constipation, bloating, diarrhea, indigestion, high blood pressure, heart rate irregularities, sleeplessness, seizures, heart attacks, strokes, death, vomiting, flatulence
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  • 51.
  • 52. _____legal, illegal, prescription and over-the-counter substance(s) used; _____amount/route of administration/frequency/duration of use; _____when started using; _____why using/used; _____last use; _____blood alcohol level and time; _____breath test result and time; _____urine drug screen results and time; _____CIWA score and time; _____COWS score and time; _____CAGE score; Prescription drug interview questions
  • 53. _____history of blackouts; _____history of intoxication or withdrawal delirium; _____history of intoxication or withdrawal seizures; _____history of substance induced psychosis, mania, anxiety or depression; _____longest time clean/sober, _____history of addiction treatment; _____history of addiction support; _____history of addiction education; _____history of substance related legal problems; _____history of physical problems as a result of using; and _____problems at home, work or school as a result of using.
  • 54.
  • 55.
  • 56.
  • 57.
  • 58.
  • 59.   For each item, write in the number that best describes the patient’s signs or symptom.  Rate on just the apparent relationship to opiate withdrawal.  For example, if heart rate is increased because the patient was jogging just prior to assessment, the increase pulse rate would not add to the score.   Clinical Opiate Withdrawal Scale (COWS) .   Patient’s Name:___________________________                         Date: ______________
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  • 61.
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  • 64.
  • 65.
  • 66.       Score: 5-12 = mild; 13-24 = moderate; 25-36 = moderately severe; more than 36 = severe withdrawal                                   Total scores   with observer’s initials
  • 67.
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