Seeking for opportunities which utilize innovative and technical skills in the biotechnology/medical devices area

1. Junyu Ma, Ph.D
Curriculum Vitae
Columbus, OH 43202
junyuma@gmail.com
(803)-586-2871

2. Objective
Results-oriented and self-motivated biomedical engineering professional
seeking R&D position in Biotech/Medical Device industry
Key Qualifications
•Over
10 years solid professional experience in­­ cell culture, target drug
delivery and cancer diagnosis device development
• In­depth knowledge of using principle of cell biology, molecular biology,
materials science and engineering to solve biotechnology problems
• Excellent hands on skills of cell culture, cell based assay, polymer
synthesis, drug loaded nanoparticle preparation and medical device
fabrication
• Strong analytical, problem solving and multitasking skills coupled with
ability to work both independently and as part of a multidisciplinary team
• Eligible to working for any employers in USA without sponsorship

3. Education
2006~2011
Ph.D. in Chemical Engineering,
University of South Carolina,
Columbia, SC
2003~06
M.S. in Biochemical
Engineering, Dalian Institute of
Chemical Physics. P.R. China
1999~2003
B.S. in Life Sciences,
University of Science and
Technology of China

4. Technical Skills
Cell Biology Techniques:
mammalian and bacteria cell culture, cell-based
toxicity test, bacteria transformation, cell
transfection, flow cytometry, fluorescent
microscopy, confocal microscopy
Immunology Techniques:
immunostaining, ELISA development
Molecular Biology
Techniques:
RNA and DNA Extraction, PCR, DNA Gel Analysis,
Western Blotting
Animal Manipulation:
handling and breeding, primary cells
generation, injection, blood withdrawal,
survival surgery and post-operative care of
rodents
GPC, HPLC, LC-MS, NMR, SEM, spectrophotometry
Analytical Techniques:

5. Professional Experience
Postdoctoral Researcher, The Ohio State University,
Department of Chemical& Biomolecular Engineering
May 2011-present
•• Develop a non-invasive detection method, tethered
Develop a non-invasive detection method, tethered
cationic lipoplex nanoparticles biochip, to simultaneously captures
cationic lipoplex nanoparticles biochip, to simultaneously captures
and characterize tumor biomarkers such as circulating tumors cells
and characterize tumor biomarkers such as circulating tumors cells
and exosomes.
and exosomes.
•• Successfully generated induced neuron from embryonic and adult
Successfully generated induced neuron from embryonic and adult
fibroblast cells with nonviral method, achieving low tumorgenicity
fibroblast cells with nonviral method, achieving low tumorgenicity
and mutation compared with traditional viral method
and mutation compared with traditional viral method
•• Fabricated a multifunctional device by combining release chamber
Fabricated a multifunctional device by combining release chamber
and cell microencapsulation for therapeutic and pharmaceutics
and cell microencapsulation for therapeutic and pharmaceutics
applications, such as treating diabetics and monitoring inflammation
applications, such as treating diabetics and monitoring inflammation

6. Professional Experience
Research Assistant
August
2006-May 2011
University of South Carolina, Department of Chemical
Engineering
“Tissue engineered bone regeneration in a biodegradable osteoinductive scaffold”
“Tissue engineered bone regeneration in a biodegradable osteoinductive scaffold”
•• Studied methods for synthesis of complex organic molecules, such as macromers and peptides
Studied methods for synthesis of complex organic molecules, such as macromers and peptides
•• Implemented chemical variations to polymers to introduce functionality
Implemented chemical variations to polymers to introduce functionality
•• Studied techniques for culture, differentiation, and analysis of bone marrow stromal cells
Studied techniques for culture, differentiation, and analysis of bone marrow stromal cells
•• Characterized the biocompatibility and osteogenic potential of scaffolds in vivo (subcutaneous
Characterized the biocompatibility and osteogenic potential of scaffolds in vivo (subcutaneous
implantation,
implantation,
critical femoral defect of rats, and others ))
critical femoral defect of rats, and others
““

7. Professional Experience
Research Assistant
August
2006-May 2011
University of South Carolina, Department of Chemical
Engineering
“Multi-functional nanoparticles for drug delivery in vitro and in vivo study”
“Multi-functional nanoparticles for drug delivery in vitro and in vivo study”
•• Conjugated and encapsulated rhBMP-2 in NPs for differentiation of bone marrow stromal
Conjugated and encapsulated rhBMP-2 in NPs for differentiation of bone marrow stromal
cells
cells
•• Encapsulated Paclitaxel in biodegradable self-assembled core-shell poly(lactide-coEncapsulated Paclitaxel in biodegradable self-assembled core-shell poly(lactide-coglycolide ethylene oxide fumarate) nanoparticles for targeted anti-tumor drug delivery
glycolide ethylene oxide fumarate) nanoparticles for targeted anti-tumor drug delivery
““

8. Professional Experience
Research Assistant
August 2003May 2006
Dalian Institute of Chemical Physics
• Fabricated artificial pancreas based on cell
• Fabricated artificial pancreas based on cell
microencapsulation technology to treat diabetes
microencapsulation technology to treat diabetes
• Transplanted alginate-chitosan-alginate
• Transplanted alginate-chitosan-alginate
microencapsulated bovine chromaffin cells to mice
microencapsulated bovine chromaffin cells to mice
intraperitoneal cavity, achieving long term analgesic
intraperitoneal cavity, achieving long term analgesic
effect
effect
• Immobilized endostatin secreting CHO cells in
• Immobilized endostatin secreting CHO cells in
microcapsules and optimized production of endostatin
microcapsules and optimized production of endostatin
in bioreactors
in bioreactors

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Publications
1. J. Ma, X. He, E. Jabbari. “Osteogenic Differentiation of Marrow Stromal Cells
on Random and Aligned Electrospun Poly(L-lactide) Nanofibers”. Annals of
Biomedical Engineering. 2011, 39(1): 14-25
2. X. He, J. Ma, E. Jabbari. “Migration of marrow stromal cells in response to
sustained release of stromal-derived factor-1α from poly(lactide ethylene oxide
fumarate) hydrogels”. International Journal of Pharmaceutics. 2010, 390(2):107116
3. W. Xu, J. Ma, X. He, E. Jabbari. “Material properties and osteogenic
differentiation of marrow stromal cells on fiber-reinforced laminated hydrogel
nanocomposites”. Acta Biomaterialia. 2010, 6(6):1992-2002
4. A.E. Mercado, J. Ma, X. He, E. Jabbari. “Release characteristics and osteogenic
activity of recombinant human bone morphogenetic protein-2 grafted to novel selfassembled poly(lactide-co-glycolide fumarate) nanoparticles”. J. Control. Release.
2009, 140: 148-156.
5. X. He, J. Ma, A. E. Mercado, W. Xu, E. Jabbari. “Cytotoxicity of Paclitaxel in
Biodegradable Self-Assembled Core-Shell Poly(Lactide-Co-Glycolide Ethylene Oxide
Fumarate) Nanoparticles”. Pharm. Res. 2008, 25(7):1552-1562.
6. X. He, J. Ma, E. Jabbari. “Effect of grafting RGD and BMP-2 protein-derived
peptides to a hydrogel substrate on osteogenic differentiation of marrow stromal
cells”. Langmuir. 2008, 24 (21): 12508–12516
7. S. Moeinzadeh, S. Khorasani, J. Ma, X. He, E. Jabbar. “Synthesis and gelation
characteristics of photo-crosslinkable star Poly(ethylene oxide-co-lactideglycolide acrylate) macromonomers”. Polymer. 2011,52(18): 3887–3896
8. J. Zhou, Y. Zhang, W. Wang, J. Ma, H. Zhang, X. Guo, X. Ma. “The Effect of

10. •
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Publications
1. J. Ma, X. He, E. Jabbari. “Osteogenic Differentiation of Marrow Stromal Cells
on Random and Aligned Electrospun Poly(L-lactide) Nanofibers”. Annals of
Biomedical Engineering. 2011, 39(1): 14-25
2. X. He, J. Ma, E. Jabbari. “Migration of marrow stromal cells in response to
sustained release of stromal-derived factor-1α from poly(lactide ethylene oxide
fumarate) hydrogels”. International Journal of Pharmaceutics. 2010, 390(2):107116
3. W. Xu, J. Ma, X. He, E. Jabbari. “Material properties and osteogenic
differentiation of marrow stromal cells on fiber-reinforced laminated hydrogel
nanocomposites”. Acta Biomaterialia. 2010, 6(6):1992-2002
4. A.E. Mercado, J. Ma, X. He, E. Jabbari. “Release characteristics and osteogenic
activity of recombinant human bone morphogenetic protein-2 grafted to novel selfassembled poly(lactide-co-glycolide fumarate) nanoparticles”. J. Control. Release.
2009, 140: 148-156.
5. X. He, J. Ma, A. E. Mercado, W. Xu, E. Jabbari. “Cytotoxicity of Paclitaxel in
Biodegradable Self-Assembled Core-Shell Poly(Lactide-Co-Glycolide Ethylene Oxide
Fumarate) Nanoparticles”. Pharm. Res. 2008, 25(7):1552-1562.
6. X. He, J. Ma, E. Jabbari. “Effect of grafting RGD and BMP-2 protein-derived
peptides to a hydrogel substrate on osteogenic differentiation of marrow stromal
cells”. Langmuir. 2008, 24 (21): 12508–12516
7. S. Moeinzadeh, S. Khorasani, J. Ma, X. He, E. Jabbar. “Synthesis and gelation
characteristics of photo-crosslinkable star Poly(ethylene oxide-co-lactideglycolide acrylate) macromonomers”. Polymer. 2011,52(18): 3887–3896
8. J. Zhou, Y. Zhang, W. Wang, J. Ma, H. Zhang, X. Guo, X. Ma. “The Effect of