2. What was known about
DNA?
• It could be found in almost
all cells
• It contained phosphorus in
the form of phosphate.
3. What was known about
DNA?
• It contained a sugar,
deoxyribose.
• It contained 4 forms of nitrogen
containing bases; purines -
adenine and guanine and
pyrimidines - thymine and
cytosine.
9. nucleotide monomer nucleotide
(sugar, phosphate and nitrogen polymer
base A, T, C orG) (chain)
10. Erwin Chargaff
calculated a “rough
equivalent” between
adenine and thymine
molecules and between
cytosine and guanine
molecules.
adenine guanine thymine cytosine
17. DNA Replication or
Synthesis
• enzymes separate or unzip
the two strands (breaks the
H bonds)
• the two unwound strands
each become a template for
the new strands to be built
• the new nucleotides are
paired and inserted
• enzymes “proofread the
new strands and seals the
base pair