2. Illustration of kinetic competition between protein aggregation
and folding
Illustration of the molecular environment inside a cell
3. A basic representation of aggregate formation and the factors
responsible for it
Cytochrome C
4. ThT fluorescence emission spectra of native cyt c and
cyt c in the presence of different crowding agents (P4
and P6) incubated for 16 h at room temperature
Turbidity increase from native cyt c to cyt c in
presence of P4 and P6 along with different time
intervals
5. Kinetics of the cyt c aggregation monitored
by using relative ThT spectra
Soret absorption spectra of native cyt c and spectra of cyt c
supplemented with 200 mg/ml P4 and P6
6. Fluorescence microscopy study shows native cyt c (A), (B) represents the cyt c
incubated with P4 and (C) showing incubation of cyt c with P6 at 16 h