1. PUBLICATION
1. Samanta, H. K., and S.B.Bhattacharjee. 1977. Thymineless death in Escherichia
coli. Z. Naturforch. 32,sec.C:835-838.
2. Bhattacharjee, S. B., and H. K. Samanta. 1978. Radiation response of thymine
starved bacteria. Radiation Res. 74:144-151.
3. Slattery, E., N. Ghosh, H. Samanta, and P. Lengyel. 1979. Interferon, double
stranded RNA and RNA degradation: Activation of an endonuclease by (2'-5')
(A).Proc. Natl. Acad. Sci. USA 76:4778-4782.
4. Slattery, E., N. Ghosh, H. Samanta, and P. Lengyel. 1979. Mediators of interferon
action: On the activation of an Endonuclease by (2'-5') (A)n. pp. 521-528 in
Interferon: Properties and Clinical Uses (eds. A. Khan and G. L. Dorn) Wadley
Institutes of Molecular Medicine.
5. Dougherty, J. P., H. Samanta, P. J. Farrell, and P. Lengyel. 1980. Interferon, double
stranded RNA and RNA degradation: Isolation of homogeneous pppA(2'p5')n-1
synthetase from Erlich ascites tumor cells. J. Biol. Chem. 255:5813-5816.
6. Lengyel, P., R. Desrosiers, R. Broeze, E. Slattery, H. Taira, J. Dougherty, H.
Samanta, J. Pichon, P. Farrell, L. Ratner, and G. Sen. 1980. Biochemistry of the
interferon system. pp. 219-226 in Microbiology (ed. Schlessinger, D.) ASM
publication.
7. Lengyel, P., H. Samanta, J. Pichon, J. Dougherty, E. Slattery, and P. Farrell. 1980.
Double stranded RNA and the enzymology of interferon action. Ann. N.Y. Acad. Sci.
350:441-447.
8. Mukherjee, A., H. Samanta, and A. Guha. 1980. Construction and characterization
of a recombinant plasmid containing the entire biotin gene of E. coli-K-12. Plasmids
and Transposons: Environmental Effects and Maintenance Mechanism. (ed.
Stuttard) Academic Press, New York. pp. 379-386.
9. Samanta, H., J. Dougherty, and P. Lengyel. 1980. Synthesis of (2'-5')(A)n from ATP:
Characteristics of the reaction catalyzed by (2'-5')(A)n synthetase purified from
mouse Ehrlich ascites tumor cells treated with interferon. J. Biol. Chem. 255: 9807-
9813.
10. Lengyel, P., R. Broeze, B. Jayaram, J. Pichon, E. Slattery, J. Dougherty, H.
Samanta, and G. Floyd-Smith,. 1981. Studies on the biochemistry of the interferon
system. pp. 356-367 in The Role of RNA in Development and Reproduction (eds. M.
C. Niu and H. H. Chauang) Science Press, Beijing.
11. Yang, K., H. Samanta, J. Dougherty, B. Jayaram, R. Broeze, and P. Lengyel. 1981.
Interferons, double stranded RNA and RNA degradation: Isolation and
characterization of homogeneous human (2'-5')(A)n synthetase. J. Biol. Chem.
256:9324-9328.
12. Dougherty, J., H. Samanta, G. Floyd-Smith, R. Broeze, B. M. Jayaram, and P.
Lengyel. 1982. Enzymology of Interferon action: The (2'-5')(A)n synthetase-RNase L
pathway." Tex. Rep. Biol. Med. 41: 443-451.
2. Page 2 of 9
Himadri Samanta
13. Samanta, H., J. P. Dougherty, M. E. Brawner, H. Schmidt, and P. Lengyel. 1982.
Interferon action: Cloning of cDNA segments complementary to messenger RNAs
induced by interferons." pp. 59-72 in Interferons (eds. T. C. Merigan, R. M. Friedman
and C. F. Fox) Academic Press, New York.
14. Jayaram, B. M., H. Schmidt, O. Yoshie, H. Samanta, G. Floyd-Smith, and P.
Lengyel. 1983. Interferon action: (A) Interferons as inducers of mRNA and protein
synthesis, (B) Crosslinking of beta interferon to cell surface receptors" pp. 157-175 in
Humoral Factors in Host Defence (eds. Y. Yamamura et al.) Academic Press, New
York.
15. Samanta, H., O. Yoshie, H. Schmidt, G. St. Laurent, B. Jayaram, E. S. P. Reddy, S.
Weissman, and P. Lengyel. 1983. Interferons as activators of gene expression:
Induction of mRNAs specifying major histocompatibility complex antigens. (2'-5')(A)n
synthetase and proteins of unknown function." in Contribution of Modern Biology to
Medicine (ed. V. Bertazzoni) Academic Press, London.
16. Samanta, H., O. Yoshie, H. Schmidt, G. St. Laurent, G. Floyd-Smith, B. M. Jayaram,
and P. Lengyel. 1983. Interferons as inducers of RNA and protein synthesis. pp. 239-
244 in Biology of the Interferon System (eds. E. DeMaeyer and H. Schellekens)
Elsevier Science Publishers, Amsterdam.
17. St. Laurent, G., O. Yoshie, G. Floyd-Smith, H. Samanta, P. B. Sehgal, and P.
Lengyel. 1983. Interferon action: Two (2'-5')(A)n synthetases specified by distinct
mRNAs in Ehrlich ascites tumor cells treated with interferon.Cell.33:95-102.
18. Samanta, H., D. Pravtcheva, F. H. Ruddle, and P. Lengyel. 1984. Chromosomal
location of the mouse gene 202 which is induced by interferons and specifies a
56,000 dalton protein.J. Interferon Res. 4:295-300.
19. Engel, D. A., H. Samanta, M. E. Brawner, and P. Lengyel. 1985. Interferon action:
Transcriptional control of a gene specifying a 56,000 Da. protein in Ehrlich Ascites
Tumor cell. Virology.142:389-397.
20. Samanta, H., and P. Lengyel. 1986. Enzymatic synthesis of (2'-5') linked
oligoadenylates at the preparative scale.Method. Enzymol.119:516-521.
21. Samanta, H., D. A. Engel, H. M. Chao, A. Thakur, M. A. Garcia-Blanco, and P.
Lengyel. 1986. Interferons as gene activators: Cloning of the 5' terminus and the
control segment of an interferon activated gene.J. Biol. Chem.261:11849-11858.
22. Samanta, H., and D. Engel. 1987. Deionization of Formamide with Biorad AG501-
X(D)." J. Biochem. Biophys. Methods.14:261-266.
23. Samanta, H. K. 1987. The Challenge of Hepatitis B Virus.The Microorganisms and
Industry 13(3):3-11.
24. Choubey, D., J. Snoddy, V. Chaturvedi, E. Toniato, G. Opdenakker, A. Thakur, H.
Samanta, D. Engel, and P. Lengyel. 1989. Interferons as Gene Activator: Indications
of repeated gene duplication during the evolution of a cluster of interferon-activable
genes on murine chromosome 1.J. Biol. Chem.264:17182-17189.
25. Samanta, H., and B. W. Youn. 1989. Expression of Hepatitis B Virus surface antigen
containing pre-S region in mammalian cell culture system.Vaccine.7:69-76.
3. Page 3 of 9
Himadri Samanta
26. Youn, B. W., and H. Samanta. 1989. Purification and characterization of pre-S
containing Hepatitis B surface antigens in recombinant mammalian cell
culture.Vaccine.7:60-68.
27. Park, D. H., T. Wessel, H. Baker, T. H. Joh, and H. Samanta. 1991. Characterization
of recombinant bovine phenylethanolamine N-methyltransferase expressed in a
mouse C127 cell line. Mol. Brain Res. 10:213-218.
28. Samanta, H., and Y. J. Kim. 1991. High level expression of human tissue-type
plasminogen activator gene in mouse C127 cell". J. Biotechnology, 20:1-16.
29. Sen, I., H. Samanta, W. Livingston, and G. C. Sen. 1991. Establishment of
transfected cell lines producing testicular angiotensin-converting enzyme: structural
relationship between its secreted and cell bound forms.J. Biol. Chem.266:21985-
21990.
30. Ghosh, S. K., J. Kusari, S. K. Bandyopadhyay, H. Samanta, R. Kumar, and G. C.
Sen. 1991. Cloning, Sequencing and expression of two murine 2'-5' oligoadenylate
synthetases: structure-function relationships.J. Biol. Chem. 266:15293-15299.
31. Oh, K-O., Z. Zhou, K. Kim, H. Samanta, M. Fraser, Y. J. Kim, H. E. Broxmeyer, and
B. S. Kwon. 1991. Identification of cell surface receptors for murine macrophage
inflammatory protein-1a. J. Immunol.147:2078-2983.
32. Park, D. H., K. T. Kim, M. U. Choi, H. Samanta, and T. H. Joh. 1992.
Characterization of bovine aromatic L-amino acid decarboxylase expressed in a
mouse cell line:comparison with native enzyme.Mol. Brain Res.16:232-238.
33. Samanta, H., R. Rose, A. K. Patick, C. M. Bechtold, J. Trimble, H. Li, A. Lee, R.
Colonno, and P. F. Lin. 1994. Characterization of a mutant HIV-1 reverse
transcriptase resistant to (+)-(5S)-4,5,6,7-tetrahydro-5-methyl-6-(3-methyl-2-butenyl)-
imidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-thione (TIBO R82150). Antiviral
Chemistry and Chemotherapy, 5:278-281.
34. Lin, P. F., H. Samanta, R. E. Rose, A. K. Patick, J. Trimble, C. M. Bechtold, D. R.
Revie, N. C. Khan, M. E. Federici, H. Li, A. Lee, R. Anderson, and R. J. Colonno.
1994. Genotypic and Phenotypic analysis of human immunodeficiency virus type 1
isolates from patients on prolonged stavudine therapy. J. Infect. Dis. 170:1157-1164.
35. Lin, P. F., H. Samanta, C. M. Bechtold, C. A. Deminie, A. K. Patick, M. Alam, K.
Riccardi, R. E. Rose, R. J. White, and R. J. Colonno. 1996. Characterization of
Siamycin I, a human immunodeficiency virus fusion inhibitor. Antimicrob. Agents
Chemother. 40: 133-138.
36. Kervinen, J., N. Thanki, A. Zdanov, J. Tino, J. Barrish, P. F. Lin, R. Colonno, K.
Riccardi, H. Samanta, and A. Wlodawer. 1996. Structural analysis of the native and
drug-resistant HIV-1 proteinases complexed with an aminodiol inhibitor. Prot. Pep.
Lett. 3:399-406.
37. Deminie, C., C. M. Bechtold, K. Riccardi, R. E. Rose, H. Samanta, P. F. Lin, and R.
J. Colonno. 1998. Clinical HIV-1isolates remain sensitive to stavudine following
prolong therapy. AIDS. 12:110-112.
4. Page 4 of 9
Himadri Samanta
38. Walker, M. A., T. Johnson, Z. Ma, J. Banville, R. Remillard, O. Kim, Y. Zhang, A.
Stabb, H. Wong, A. Torri, H. Samanta, Z. Lin, C. Deminie, B. Terry, M. Krystal, and
N. Meanwell. 2006. Triketoacid inhibitors of HIV-integrase: a new chemotype useful
for probing the integrase pharmacophore. Bioorg. Med. Chem. lett. 16:2920-2924.
39. Walker, M. A., T. Johnson, Z. Ma, Y. Zhang, J. Banville, R. Remillard, S. Plamondon,
H. Pendri, H. Wong, D. Smith, A. Torri, H. Samanta, Z. Lin, C. Deminie, B. Terry, M.
Krystal, and N. Meanwell. 2006. Exploration of the diketoacid integrase inhibitor
chemotype leading to the discovery of the anilide-ketoacid chemotype. Bioorg. Med.
Chem. lett. 16:5818-5821.
40. Walker, M. A., T. Johnson, B. N. Naidu, J. Banville, R. Remillard, S. Plamondon, A.
Martel, C. Li, A. Torri, H. Samanta, Z. Lin, I. Dicker, M. Krystal and N. Meanwell.
2007. Benzylamide-ketoacid inhibitors of HIV-integrase. Bioorg. Med. Chem. lett.
17:4886-4890.
41. Dicker, I. B., H. K. Samanta, Z. Li, Y Hong, Y Tian, J. Banville, R. R. Remillard, M. A.
Walker, D. R. Langley and M. Krystal. 2007. Changes to the HIV long terminal repeat
and to HIV integrase differentially impact HIV integrase assembly, activity, and the
binding of strand transfer inhibitors. J. Biol. Chem. 282:31186-31196.
42. Langley, D.R., H. K. Samanta, Z. Lin, M. Walker, M. Krystal, and I. Dicker. 2008.
The terminal (catalytic) adenosine of the HIV LTR controls the kinetics of binding and
dissociation of HIV integrase strand transfer inhibitors. Biochemistry 47: 13481-
13488.
43. Dicker, I. B. Terry, Z. Lin, S. Bollini, H. K. Samanta, V. Gali, M. A. Walker, and M.
Krystal. 2008. Biochemical analysis of HIV-1 integrase variants resistant to starnd
transfer inhibitors. J. Biol. Chem. 283:23599-23609.
ABSTRACTS
1. Samanta, H., and S. B. Bhattacharjee. 1974. Thymineless death in E. coli. Abstr.
Seventh All India Symposium on Biophysics, New Delhi, India.
2. Samanta, H., and S. B. Bhattacharjee. 1976. Thymineless death and recovery in E.
coli. Abstr. Eighth All India Symposium on Biophysics, Santinikatan, W. Bengal,
India.
3. Dasgupta, C. K., H. Samanta, and A.Guha. 1978. Electron microscopic studies of
the isolated DNA fragments containing biotin gene Escherichia coli K-12. Ninth
International Congress of Electron Microscopy. Toronto, Canada. 2:198-199.
4. Lengyel, P., E. Slattery, H. Taira, R. Broeze, M. F. Dubois, P. J. Farrell, N. Ghosh,
and H. Samanta. 1979. Biochemistry of interferons: Structure and action. Fed. Proc.
38:777.
5. Samanta, H., J. P. Dougherty, and P. Lengyel. 1980. Interferon action:
Characteristics of (2'-5')(A)n synthetase from Ehrlich ascites tumor cells treated with
interferon. Second Congress of the FAOB and Golden Jubilee Ann. Meeting of the
SBC (India).
5. Page 5 of 9
Himadri Samanta
6. Samanta, H., J. P. Dougherty, and P. Lengyel. 1980. Synthesis of (2'-5')(A)n from
ATP: Characteristics of the reaction, stoichiometry and equilibrium. First Annual
International Meeting on Interferon. Washington.
7. Lengyel, P., H. Samanta, J. P. Dougherty, M. E. Brawner, and H. Schmidt. 1982.
Interferons and gene activation: Cloning of cDNA segments complementary to
messenger RNAs induced by interferons.J. Cell. Biochem. Supplement 6:81.
8. Schmidt, H., O. Yoshie, H. Samanta, S. Reddy, S. Weissman, and P. Lengyel. 1982.
Effects of interferons on gene expression.Third Ann. Intl. Congress for Interferon
Research, Miami, Florida.
9. Samanta, H., G. St. Laurent, O. Yoshie, and P. Lengyel. 1983. Interferons and
induction of genes. XV Intl. congress of Genetics, New Delhi, India. Abstr. part 1:124.
10.Samanta, H., H. Chao, D. Engel, S. Tominaga, S. Vijaysarathy, and P. Lengyel.
1984. Interferons as activators of gene expression. Sixth Intl. Congress of Virology,
Japan.
11.Samanta, H., K. H. Choi, H. S. Kang, G. Pavlakis, H. H. Hyun, and H. M. Moon.
1986. Expression of Hepatitis B Surface antigen containing pre-S region in
mammalian cell. Abstract Annual meeting. Korean Society for Microbiology. Seoul,
Korea. p.15.
12.Samanta, H., and K. Choi. 1988. Expression of pre-S region of Hepatitis B virus.In
Advances in Gene Technology: Protein Engineering and Production (eds. K. Brew et
al.) IRL press. p 177.
13.Samanta, H., E. Pasnikowski, C. Jue, and Y .J. Kim. 1988. Cloning and expression
of human tissue plasminogen activator in a mammalian cell culture system. Abstract.
31st. Annual meeting of Korean Society for Applied Microbiology Kwang-ju, Korea.
p.15.
14.Samanta, H. 1989. Cloning and expression of human t-PA in a mouse cell line. The
First U.S.-Japan Symposium on Biotechnology, St. Petersburg, Florida. Abstract p.
46.
15.Samanta, H., H. Baker, T. Wessel, T. H. Joh, and D. H. Park. 1989. Expression of
enzymatically active phenylethanolamine N-methyltransferase (PNMT) in a mouse
fibroblast cell line.19th Annual Meeting, Society of Neuroscience. Abstracts, 15,
1312.
16.Joh, T. H., J. M. Carroll, U. J. Kang, A. Towle, and H. Samanta. 1990. Molecular
analysis and regulation of dopamine synthesizing enzymes.Abstract. UCLA
Symposium.
17.Chen, J. W., H. Li, J. Trimble, M. Alam, D. Pauletti, H. Samanta, K. Felsenstein,
and P. F. Lin. 1991. In search of HIV tat inhibitors. Second Annual PRI Research
Scientist Symposium.
6. Page 6 of 9
Himadri Samanta
18.Samanta, H., R. Rose, A. Patick, C. Bechtold, J. Trimble, H. Li, A. Lee, P. F. Lin, and
R. Colonno. 1992. Characterization of a mutant HIV-1 reverse transcriptase resistant
to a non nucleoside inhibitor (R82150). Third Annual PRI Scientific Poster Session.
19.Samanta, H., R. Rose, A. Patick, C. Bechtold, J. Trimble, H. Li, A. Lee, P. F. Lin,
and R. Colonno. 1992. Characterization of a mutant HIV-1 reverse transcriptase
resistant to a non nucleoside inhibitor (R82150).Scilights, 3(4):S4.
20.Li, H., H. Samanta, R. Rose, A. Patick, C. Bechtold, M. Alam, J. Trimble, and P. F.
Lin. 1993. Effect of RNase H domain mutation on the TIBO resistance of an HIV-1
reverse transcriptase mutant. Fourth Annual Research Scientist Symposium.
21.Samanta, H., C. Bechtold, C. Deminie, M. Alam, K. Riccardi, B. Rose, A. Patick, R.
White, R. Colonno, and P. F. Lin. 1995. Characterization of Siamycin I, a fusion
inhibitor. J. Cell Biochem 21B:197.
22.Samanta, H., K. Riccardi, H. Li, B. Rose, R. Dalterio, M. Chatterjee, P. F. Lin, R.
Colonno, and R. Kim. 1996. The coordination Zn(II) is essential for the biochemical
activities of HIV integrase.15th Annual Meeting, ASV, July 13-17, 1996, Canada.
23.Samanta, H., S. H. Day, and M. K. Krystal. 1997. Strand transfer screen for
inhibitors of
HIV integrase. Eighth Annual Scientific Poster Session.
24.Lin, Z., H. Samanta, A. Torri, S. Day, and M. Krystal. 1998. Development of a
specific plate assay of HIV integrase strand transfer activity. Ninth annual
Wallingford scientific symposium.
25.Fang, H., D. S. Dodd, N. Meanwell, A. Staab, K. Yeoung, Z. Zhang, B. Venables, M.
Krystal, A. Torri, C. Deminie, H. Samanta, and M. Deshpande. 1998. Identification of
tissue culture active inhibitors of HIV integrase using combinatorial chemistry
techniques. Ninth Annual Scintific Poster Sessions.
26.Xie, D., S. Scherif, S. Farmer, J. Scheffler, H. Samanta, and N. Yan. 1999. A new
form of HIV integrase core domain protein.Tenth Annual Wallingford Scientific
Symposium.
27.Torri, A., H. Samanta, C. Deminie, K. Riccardi, Z. Lin, and M. Krystal. 1999.
Identification of a novel inhibitor of HIV.Tenth Annual Wallingford Scientific
Symposium.
28.Ma, Z., M. A. Walker, N. Meanwell, A. Torri, H. Samanta, Z. Lin, and M. Krystal.
2000.
Deining the pharmacophore for BMS-301894 related HIV integrase inhibitors.
Eleventh
Wallingford Scientific Symposium.
29.Lin, Z., H. Samanta, A. F. Torri, B. Terry, and M. Krystal. 2000. Development and
optimization of an in vitro assay for HIV integrase strand transfer activity. Eleventh
Wallingford Scientific Symposium.
7. Page 7 of 9
Himadri Samanta
30.Zhang,Y., O. Kim, M. Walker, N. Meanwell, A. Staab, A. Torri, H. Samanta, Z. Lin, B.
Terry, M. Krystal, and Y. Sun. 2000. Synthesis and Biological Activity of BMS-
301894 Analogs.Eleventh Wallingford Scientific Symposium.
31.Torri, A. F., H. Samanta, Z. Lin, C. Deminie, K. Riccardi, B. Terry, and M. Krystal.
2000. Modification of the gel based PINC assay for the evaluation of compounds in
the HIV-IN program. Eleventh Wallingford Scientific Symposium.
32.Samanta, H., A. Torri, B. Terry, Z. Lin, C. Deminie, K. Riccardi, and M. Krystal. 2000.
Mapping of BMS-301894 resistance. Eleventh Wallingford Scientific Symposium.
33.Kim, N., H. Samanta, J. Zewinski, and J. O’Connell. 2001. Adaptation of an HIV
screen to a HTS. Wallingford Scientific symposium.
34.Combrink, K. D. and H. Samanta. 2003. The code of Life. 59th Southwestern
Regional Meeting of the American Chemical Society, Oklahoma City.
35.Samanta, H., I. Dicker, M. Zeng, Z. lin, L. Pajor, J. Zheng, T. Philipp, and M. Krystal.
2004. Development of an in vitro glucuronidation assay for compound evaluation in
the HIV integrase inhibitor program. 2004. Fourteenth Annual R&D scientific
symposium, New Brunswick, NJ.
36.Dicker, I., Z. Li, Z. lin, H. Samanta, B. Terry, S. Bollini, C. Deminie, and M. Krystal.
2004. Detailed biochamical analysis of WT and BMS-538203 resistant HIV-1
integrase. Fourteenth Annual R&D scientific symposium, New Brunswick, NJ.
37.Lin, Z., I. Dicker, H. Samanta, B. Terry, H. Scarnati, S. Bollini, X. Feng, V. Ekhato, L.
Paror, M. Mathew, M. Zeng, J. Zheng, and M. Krystal. 2004. Integrase serum shift
assay(ISSA): A quick and easy method to predict human serum binding of HIV
integrase inhibitors. Fourteenth Annual R&D scientific symposium, New Brunswick,
NJ.
38.Dicker, I., B. Terry, Z. Lin, Z. Li, S. Bolloni, H. Samanta, V. Gali, M. A. Walker, and
M. Krystal. 2008. Biochemical Analysis of HIV-1 integrase variants resistant to
strand transfer inhibitors. Eighteenth Annual R&D scientific symposium, Hopewell,
NJ.
39.Samanta, H., D. Connors, I. Dicker, and M. Krystal. 2008. A novel assay for RAG
activity: Lack of inhibitionof RAG by integrase inhibitor BMS-727740. Eighteenth
Annual R&D scientific symposium, Hopewell, NJ.
40.McAuliffe, B., C. Deminie, L. Discotto, B. Minassian, H. Samanta, M. Krystal, and C.
Cianci. 2008. A novel influenza polymerase inhibitor is discovered. Eighteenth
Annual R&D scientific symposium, Hopewell, NJ.
41.Samanta, H., B. Nowicka-Sans, T. Protack, A. Regueiro-Ren, J. Swidorski, Z. Liu, D.
Calambur, M. Witmer, M. Krystal, N. Meanwell, and I. Dicker. 2009. An in-vitro
cleavage assayfor HIV-1 maturation inhibitors. Nineteenth Annual R&D scientific
symposium, Princeton, NJ.
42.Lin, Z., I. Dicker, B. Terry, T. Protack, H. Samanta, Z. Li, V. Gali, and M.Krystal.
2009. Probing the mechanismof integrase inhibitor pharmacodynamics. Nineteenth
Annual R&D scientific symposium, Princeton, NJ.
8. Page 8 of 9
Himadri Samanta
43.Li, Z., C. Deminie, L. Discotto, B. Minassian, H. Samanta, C. Cianci, and M. Krystal.
2009. Lack of effect of influenza polymerase and surface proteins on the action of
BMS replication inhibitors. Nineteenth Annual R&D scientific symposium, Princeton,
NJ.
44.Lin, Z., H. Samanta, L. Elkin, I. Dicker, B. Terry, T. Protack, Z. Li, L. Discotto, C.
cianci, and M. Krystal. 2010. Development of In Vitro assays for HIV integrase-
LEDGF program. Twentieth Annual R&D scientific symposium, Princeton, NJ.
45.Nowwicka-Sans, B., H. Samanta, Y. Chen, S. Sit, Z. liu, J. Swidorski, A. Regueiro-
Ren, M. Krystal, and I. Dicker. 2010. HIV-1 resistance to the lead BMS maturation
inhibitors. Twentieth Annual R&D scientific symposium, Princeton, NJ.
46.Minassian, B., C. Deminie, H. Samanta, and C. Cianci. 2010. A novel BMS series
inhibits reisitant influenzanviruses generated by reverse genetics. Twentieth Annual
R&D scientific symposium, Princeton, NJ.
47.Li., C., M, Walker, Y. Ueda, J. Matiskella, Z. Lin, I. Dicker, H. Samanta, B. terry, H.
Scarnetti, C. Deminie, S. Bollini, M. Krystal, and N. Meanwell. 2010. Design,
synthesis and SAR study fo novel spiro aza-pyrimidinone HIV integrase inhibitors.
240th ACS national meeting. Boston, MA.
48.Dicker, I., B. Terry, T. Protack, Z. Lin, H. Samanta, V. Gali, N. Meanwell, M. Walker,
and M. Krystal.2011. Longer integrase inhibitor dissociation half-livesinduce
persistent anti-HIV effects in cell culture. 18th
Conference on retroviruses and
opportunistic infections. Boston, MA.
PATENTS
1. Samanta, H., and Y. J. Kim. 1990. The method of synthesis of TPA and
development of a vector for mass production. Korean patent 36122.
INTERNAL REPORTS (Author)
1. Torri, A., H. Samanta, and M. Krystal. Mechanism report on the HIV-1 integrase
inhibitor BMS-xxxxxx.. Mar. 31, 2003.
2. Terry, B., H. Samanta, and M. Krystal. Generation of HIV-1 viruses resistant to BMS-
xxxxxx the active species of BMS-538158. Mar. 31, 2003.
INTERNAL REPORTS (Investigator)
1. Detailed biochemical analyses of wild type and BMS-xxxxxx-resistant HIV-1
integrases.. Aug. 29, 2005.
2. Evaluation of Recombinant HIV clones containing BMS-xxxxxx/BMS-538158
resistance substitutions.. Aug. 31, 2005.
9. Page 9 of 9
Himadri Samanta
3. Generation of HIV-1 viruses resistant to BMS-xxxxxx. Dec. 5, 2005.
4. Phenotypic and genotypic analysis of subjects from the BMS-xxxxxx phase IIa
clinical trial.. Mar. 29, 2006.
5. Non clinical microbiology and mechanism report on the HIV-1 integrase inhibitor
BMS-xxxxxx.. Nov.29, 2007