The Role of Health Research Wales in supporting Industry Research in Betsi Cadwaladr University Health Board (BCUHB) International Clinical Trials Day 20th May 2014 Presented by Rebecca Burns, Health Research Wales, Industry Manager

1. The Role of Health Research Wales in supporting
Industry Research in BCUHB
International Clinical Trials Day 20th May 2014
Rebecca Burns - Health Research Wales Industry Manager

2. Changing Environment
Weak Economy
Reduce cost of care
and system
inefficiencies
Aging Population
Higher patient
volumes, more chronic
care, new illness,
health lifecycle
management
In the UK, the NHS faces a projected spending gap of £30bn a
year by 2021, as the number of older people with multiple long-
term conditions such as cancer, diabetes and heart disease rises
inexorably

3. Commercial Research – NHS Drivers
• Full Cost Recovery from Industry
• Capacity Building
• Drug/Device Development privately financed
• Development in Wales/UK good for employment
& economy
• Access to cutting edge treatments & technologies
• Driver to improve Best Practice
• Aids recruitment & retention of specialist staff
• “Together for Health NISCHR 2011- 2016 ” KPIs

4. The Pharmaceutical Industry is the
Leading Investor in R&D in the UK
Since 2000 the UK
has been losing
out to global
competitors

5. Percentage of patient enrolment into studies
Perception of the UK:
 Slow (site selection, study set up and delivery)
 Poor at achieving recruitment to time and target
 Expensive (compared emerging
markets such as India)

6. What is Health Research Wales?
• Recommendation made by Industry to establish separate
brand identity for commercial clinical research in Wales
• Industry facing brand of Wales
 One stop source of information and support for
industry
 Portal for industry to access NHS Wales
 Services to support the set-up and management of
commercial research studies
• Communication vehicle to promote Wales and demonstrate
Wales’ clinical research successes

11. Identifying Collaborators
Partnering Service
 Discuss viability of idea/product
 Determine clinical un-met need
 Contribute to project development

20. Photos of GPs

21. Feasibility
the Industry Perspective
 Global Competition to place a study in the UK
 Two key factors to
the decision:
 How quick it is to
get permissions
granted
 Are there
sufficient willing
patient volunteers to
take part

22. Feasibility
Clinician Perspective
 National Competition to get the study in own
health board
Fast return of EOI (Expressions of Interest)
 Successful site selection visit
 Record of successful recruitment to and
completion of study within the agreed times
 Realistic & accurate estimate of potential recruits
 Be aware of service support available & discuss
protocol requirements with departments
 Assess what research support could be needed &
Involve NISCHR CRC & Health Research Wales

27. Some Stats

28. Why do Commercial research?
• Its much easier to be part of than to start on my own
• Remuneration to the organisation
• Opportunity to treat some difficult cases, particularly in
one trial as I ran out options from the formulary
• It’s a scientific stimulus as NHS work is mainly service
• Opportunity for publication
• Access to and experience of using new or novel
treatments or devices
• Cost savings
• Raises the profile of department or service
• Funding other research Interests

29. Some feedback
I can’t thank you enough for your help and
support in completing the necessary forms for
the * study. I simply couldn’t have done it
without your help as I was on the verge of
giving up. I am sure you know that one of the
main obstacles for research in DGH is the
lack of this specialist support. I sincerely
hope that this new service will develop to
ensure that research will not be exclusive to
large institutions only.

31. Small Business Research Innovation Awards (SBRI )
£3m available to fund innovative solutions to public sector challenges
• Funded by the Welsh Government and the Technology Strategy Board,
£3m available for new projects.
• The programme aims to drive innovation in the four areas including Life
Sciences and Health
• Public sector organisations, looking for new and novel solutions to
challenges they face, can apply for a share of this new fund.
• The identified challenge is then turned into an open competition for new
technologies and ideas from businesses.
• The Programme aims to boost the research and development industry,
increase commercialisation of new technologies and create jobs and
wealth.