Health Datapalooza IV: June 3rd-4th, 2013 Illuminating Disease at the Speed of Light: How Big Data Is Accelerating Biomedical Research Convener: Marcia A. Kean, Chairman, Strategic Initiatives, Feinstein Kean Healthcare Moderator: Kevin Davies, Author, “The $1,000 Genome”; Founding Editor, Nature Genetics and Bio-IT World magazine; and Vice President Business Development, American Chemical Society Speakers: Amy P. Abernethy, Director, Center for Learning Healthcare (CLHC), Duke Clinical Research Institute Michael Cantor, Senior Director, Information Strategy and Analytics, World Research Development, Pfizer Dave King, Founder, Exaptive Robert McBurney, Chief Executive Officer, Accelerated Cure Project for Multiple Sclerosis Dietrich Stephan, Founder and Chief Executive Officer, Silicon Valley Biosystems (SV Bio) Until recently, biomedical research was conducted in small silos, separated by huge cultural and technical walls and inability to exchange data facilely. But the field is now exploding: massive amounts of complex, multi-dimensional clinical, imaging, and genomic data are being collected, aggregated, integrated, analyzed, and shared. The pioneers driving this digital transformation are working in novel collaborations among patients, providers, and scientists. In this session, speakers will showcase multimodal, computational, and analytic tools for biomarker discovery, patient stratification, and intelligent clinical decision solutions; high-speed genome profiling, with algorithms of individual and population profiles, for real-time molecular-based diagnoses of ‘mystery’ diseases; a point-of-care quality monitoring program used by clinicians, in which data are used for important research questions and then transitioned into clinical trials; and collection and aggregation of data and samples from patients with a neurological disease, enabling queries into markers of disease origins and discovery of new therapies.