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Breast Cancer
Biomarkers
L earn h ere h o w p ro t ei n s can h el p
i m p ro v e b reas t can cer d et ect i o n
There are several types of
biomarkers
By analyzing biomarkers, diagnostic tests can provide information
about tumor development to detect breast cancer at an early, more
treatable stage.
Biomarkers can be helpful in managing patients in the following
settings…
Risk Assessment
Identify factors to assess disease
susceptibility
1
vThese biomarkers are frequently associated with a
predisposition to cancer.
vThey can inform a woman's future risk of developing breast
cancer.
vHealthcare providers often recommend that individuals with
these gene mutations consider more frequent screenings in an
attempt to detect breast cancer at an early stage.
Risk Assessment
Screening
Indicate the presence of disease
2
vBiomarkers for screening and detection are real-time indicators of
the presence of cancer.
vThe body may respond to the presence of a tumor by creating and
releasing immune factors (such as antibodies) or by shedding
serum proteins, circulating tumor cells and DNA fragments into the
bloodstream.
Screening
Diagnosis
Definitive diagnosis and general typing
3
vWhile the only way to confirm a breast cancer diagnosis is by
biopsy, biomarkers can aid in diagnosis and help determine the
primary origin of the tumor.
Diagnosis
Prognosis
Asses disease aggressiveness and
likelihood of recurrence
4
vPrognostic biomarkers may provide information about a patients
expected outcome.
vSome breast cancers are more aggressive than others and
biomarkers can help determine which cancers may grow rapidly
and/or metastasize.
Prognosis
Prediction
Predict efficacy to different treatments
5
vBiomarkers may be used to predict a patient's response to
treatment.
v Or to determine the optimal drug dose or type used for breast
cancer treatment.
vSince breast cancer is a heterogeneous disease, different cancers
can respond differently to the same treatment methods.
Prediction
Monitoring
Monitor disease recurrence and
therapeutic response
6
vBiomarkers may be used to predict and monitor a patient's breast
cancer recurrence of the disease after treatment.
Monitoring
By using different types of biomarkers in breast cancer
detection, another biological view of current disease state
is available in addition to the anatomical view of breast
imaging.
What else are biomarkers doing for
breast cancer detection?
To	learn	more	about	the	role	different	types	of	biomarkers	play	in	
cancer	detection,	read	our	guide	below:
Click here to learn more!

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Breast Cancer Biomarkers

  • 1. Breast Cancer Biomarkers L earn h ere h o w p ro t ei n s can h el p i m p ro v e b reas t can cer d et ect i o n
  • 2. There are several types of biomarkers By analyzing biomarkers, diagnostic tests can provide information about tumor development to detect breast cancer at an early, more treatable stage. Biomarkers can be helpful in managing patients in the following settings…
  • 3. Risk Assessment Identify factors to assess disease susceptibility 1
  • 4. vThese biomarkers are frequently associated with a predisposition to cancer. vThey can inform a woman's future risk of developing breast cancer. vHealthcare providers often recommend that individuals with these gene mutations consider more frequent screenings in an attempt to detect breast cancer at an early stage. Risk Assessment
  • 6. vBiomarkers for screening and detection are real-time indicators of the presence of cancer. vThe body may respond to the presence of a tumor by creating and releasing immune factors (such as antibodies) or by shedding serum proteins, circulating tumor cells and DNA fragments into the bloodstream. Screening
  • 8. vWhile the only way to confirm a breast cancer diagnosis is by biopsy, biomarkers can aid in diagnosis and help determine the primary origin of the tumor. Diagnosis
  • 9. Prognosis Asses disease aggressiveness and likelihood of recurrence 4
  • 10. vPrognostic biomarkers may provide information about a patients expected outcome. vSome breast cancers are more aggressive than others and biomarkers can help determine which cancers may grow rapidly and/or metastasize. Prognosis
  • 11. Prediction Predict efficacy to different treatments 5
  • 12. vBiomarkers may be used to predict a patient's response to treatment. v Or to determine the optimal drug dose or type used for breast cancer treatment. vSince breast cancer is a heterogeneous disease, different cancers can respond differently to the same treatment methods. Prediction
  • 13. Monitoring Monitor disease recurrence and therapeutic response 6
  • 14. vBiomarkers may be used to predict and monitor a patient's breast cancer recurrence of the disease after treatment. Monitoring
  • 15. By using different types of biomarkers in breast cancer detection, another biological view of current disease state is available in addition to the anatomical view of breast imaging.
  • 16. What else are biomarkers doing for breast cancer detection? To learn more about the role different types of biomarkers play in cancer detection, read our guide below: Click here to learn more!