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BALSAMS
Balsams
• Are resinous mixtures that have large
proportions of Benzoic acid, cinnamic acid or
both; can also be esters of these acids.
• Medicinal balsams include:
– Peru Balsam
– Tolu Balsam
– Storax Balsam
– Sumatra Benzoin
Peru Balsam (Myroxylon pereirae)
Tolu Balsam (Myroxylon balsamum)
Storax (Liquidambar orientalis)
Sumatra Benzoin (Styrax benzoin)
Peruvian Balsam
• Synonyms: China oil, black balsam, Peru
balsam
• Source: Obtained from the trunk ofMyroxylon
pereirae (trunk is beaten and
scorched)
» Myroxylon – From myron (Greek word meaning
ointment)
» Pereirae – from Jonathan Pereira, an English
pharmacognosist.
Peruvian Balsam
• Family: Leguminosae
• Habitat: Central America
Peruvian Balsam (Collection)
• The balsam is collected from trees that are
around 10 years old in the months of
November to December
• Can be collected via injury (Beating and
scorching)
Peruvian Balsam
• Color: Dark brown
• Odor: Aromatic, vanilla-like
• Soluble in chloroform and chloral hydrate
• Sparingly soluble in petroleum ether and
insoluble in water
• Specific gravity: 1.14-1.17
• Not less than 45% and Not more than 70% of
esters.
Peruvian Balsam (Constituents)
Cinnamein (Benzyl cinnamate) (60%)
Peruvian Balsam (Constituents)
Styracin (Cinnamyl Cinnamate)
Peruvian Balsam (Constituents)
• Other constituents include:
–28% of resin (peruresinotannol)
–Benzoic acids
–Alcohol (nerolidol, farnesol, benzyl
alcohol)
–Small quantities of vanillin and free
cinnamic acid.
Peruvian Balsam (Uses)
• Protectant and rubefacient
• Parasiticide for skin diseases such as scabies
• Antiseptic and vulnerary
• Can be applied externally alone or in alcoholic
solution
• Can also be in an ointment form
Peruvian Balsam (Products)
Anusol suppositories
Peruvian Balsam (Products)
Wyanoid suppositories
Tolu Balsam
• Synonyms: Tolu resin, Thomas balsam,
Opobalsam
• Source: Obtained by incision from the trunk of
Myroxylon balsamum
• Family: Leguminosae
• Habitat: West Indies, Cuba, Venezuela,
Colombia
Tolu Balsam (Collection)
• The collection of balsam involves V-shaped
incisions in the bark.
• Calabash Cups receive the flow of balsam
from the incision.
• The yield per tree is 8-10 kg.
Tolu Balsam (Collection)
Tolu Balsam
• Color: Yellow; turns brown when standing
• Occurrence: A plastic solid that gradually
hardens; becoming brown.
• Odor: Aromatic; vanilla-like
• Taste: Aromatic; slightly pungent
Tolu Balsam (Constituents)
Cinnamic acid
Tolu Balsam (Constituents)
Toluresinotannol cinnamate (primary resin ester)
Tolu Balsam (Constituents)
Benzyl benzoate (primary volatile oil)
Tolu Balsam (Constituents)
• Other constituents include:
–Other resin esters (75-80%)
–Benzoate
–Other volatile oils (7-8%)
–Free benzoic acid (12-15%)
–Vanillin (2-8%)
Tolu Balsam (Uses)
• Pharmaceutic aid for compound benzoin
tincture.
• Sometimes used as an expectorant.
• Extensively used as a pleasant flavoring in
syrups.
• Used in chewing gums, perfumes, and
confectionaries.
Tolu Balsam (Products)
Baldwin’s Tolu Balsam (30 mL)
Tolu Balsam (Products)
Friar’s Balsam (Herbal Supplement; Expectorant)(29.6 mL)
Storax Balsam
• Synonym: Levant Storax, American Storax
• Source: Obtained by bruising and puncturing
the trunk of Liquidambar orientalis
• Family: Hammamelidaceae
• Habitat: Asia Minor (Turkey)
Storax Balsam(Collection)
• The collection of Storax primarily takes place
during early summer.
• Involves bruising and puncturing the bark.
• Can also be collected during autumn by
peeling and pressing.
Storax Balsam(Collection)
Storax Balsam
• Color: Grayish to Grayish Brown
• Occurrence: Less opaque semiliquid mass.
• Odor: Agreeable; balsamic
Storax Balsam (Constituents)
Cinnamic acid
Storax Balsam (Constituents)
• Other constituents include:
–Alpha and beta storesin (30% each)
–Cinnamate (10-20%)
–Styracin (5-10%)
–Free cinnamic acid
–Traces of vanillin
Storax Balsam (Uses)
• Pharmaceutic aid for compound benzoin
tincture.
• Used as a stimulant and expectorant
• Also used as an antiseptic
• Has a dose of 1g when used internally.
Storax Balsam (Products)
Baldwin’s Storax Resinoid (30 mL)
Storax Balsam (Products)
PDI Benzoin Compound Tincture U.S.P.
Siam Benzoin
• Synonym: Thailand Benzoin
• Source: Obtained by incision from the trunk of
Styrax tonkinesis
• Family: Styracaceae
• Habitat: East Indies and Southeastern Asia
(Thailand, Northern Laos, Northern
Vietnam)
Siam Benzoin (Collection)
• The collection of benzoin involves incisions in
the bark of Styrax tonkinesis.
• After 2 months, the exuding resin becomes
less sticky and firm enough to collect.
• Separate tears are scraped from trees.
• New incisions are made until the trees die.
• Resins are only produced after the incision.
Siam Benzoin (Collection)
Siam Benzoin
• Color: Yellowish white to red; turns to brown
due to oxidation.
• Occurrence: A plastic solid that gradually
hardens; becoming brown.
• Odor: Agreeable; vanilla-like
• Size: A few mm to 3cm.
Siam Benzoin (Constituents)
Coniferyl benzoate (primary constituent) (60-70%)
Siam Benzoin (Constituents)
• Other constituents include:
–Free benzoic acid(10%)
–Triterpene; siaresinol (6%)
–A trace of vanillin
Siam Benzoin (Use)
• Siam benzoin is mainly used in perfumes.
Siam Benzoin(Products)
Glamorous (Ralph Lauren)
Siam Benzoin(Products)
Eau Claire des Merveilles (Hermès)
Sumatra Benzoin
• Synonym: Indonesia Benzoin, Gum Benjamin
• Source: Obtained from the incised stem of
Styrax benzoin
• Family: Styracaceae
• Habitat: Sumatra (Western Indonesia), Java,
Borneo
Sumatra Benzoin (Collection)
• Triangular incisions are made on the stem in a
vertical row.
• The first secretion is very sticky and is rejected
• After making further incisions, a harder
secretion is obtained. (almond tears).
• Further incision, after 3 months yields a more
fluid secretion.
Sumatra Benzoin (Collection)
Sumatra Benzoin
• Color: Whitish-reddish tears
• Occurrence: Brittle mass
• Odor: Agreeable; balsamic
• Taste: Slightly arcid.
Sumatra Benzoin (Constituents)
Cinnamic acid (primary constituent)(10%)
Sumatra Benzoin (Constituents)
Benzoic acid (primary constituent)(6%)
Sumatra Benzoin (Constituents)
• Other constituents include:
–Esters of balsamic acids (Cinnamic acid
+ Benzoic acid)
–Triterpene acids
–Traces of vanillin
–Phenylpropyl cinnamate
–Cinnamyl cinnamate
–Phenylethylene
Sumatra Benzoin (Use)
• Internally: Expectorant, antiseptic
• Externally: Cosmetic, Lotion, Food, Drink,
Perfumes
• Component of incense
Sumatra Benzoin(Products)
Friar’s Balsam (Antiseptic)
Sumatra Benzoin(Products)
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