3. What Is Estrogen ? (O.o)
• Group of compounds named for their importance in both menstrual and
reproductive cycles.
• Important hormone of the females
• Responsible for the secondary sexual characters in the females.
4. Functions of Estrogen (^_^)
• Stimulate the growth of endometrium in the uterus.
• It suppress the activity of FSH, and stimulate the secretion of LH.
• It is responsible for the youthfullness of females and it controls the action
of parathormone- hormone which intake calcium ions from bones and
teeth.
• After menopause estrogen will caused osteoporosis in some women due
the activity of parathormones
5. Estrogen in Male (^_^)
• In male, estrogen does not play as important a role as it does in women
though men also have a small amount of estradiol normally in their bodies
• The amount of testosterone that men have usually does not allow
estrogen to have any significant physiological effects on the body.
• If the amount of estrogen compared to testosterone increases, it will
cause:
- weight gain especially in the midsection
-development of enlarged breasts (gynecomastia),
- decreased sex drive
6. Secretion of Estrogen (-_- )
• Produced primarily by the ovaries.
• The stimulation for secretion of estrogen comes from the Luteinizing
hormone (LH) from anterior pituitary gland.
7. Secretion of Estrogen ( -_-)
• Some of the estrogens are also produced in smaller amounts by other
tissues :
-liver
- adrenal glands
- breasts.
• Fat cells are also sources of estrogen. This is the reason why underweight
or overweight women are at risk of infertility.
8. Types of Estrogen
• Estrone
- Produce in menopause women
• Estradiol
- Produce during reproductive years
• Estriol
- Produce during pregnancy
9. Synthesis of Estrogen
• Synthesized in the theca interna cells in the ovary.
Aromatase
enzyme
Cholesterol Androstenodione Estrone
Aromatase
enzyme
Cholesterol Androstenodione Testosterone Estrone
14. Estrogen Imbalance
High Level of Estrogen
• Cause:
1. Natural Causes of High Estrogen Levels.
2. Induced Causes of High Estrogen Levels.
3. Other Causes of High Estrogen Levels :
- Obesity
- Cardiovascular disease
- Digestive problems
15. Estrogen Imbalance
High Level of Estrogen
Symptoms
Physical Mental
-Artherosclerosis -Depression
-Headaches -Panic attacks
-Cramps -Low self esteem
-Weight gain -Mood swings
-Uterine fibroids -Memory loss
-Irregular periods
16. Estrogen Imbalance
Low Level of Estrogen
• Causes:
1. Natural Causes of Low Estrogen Levels
2. Other Causes of Low Estrogen Levels:
- Lifestyle
• Diet
• Stress
• Eating disorders
• Extreme exercise
• Pituitary diseases
17. Estrogen Imbalance
Low Level of Estrogen
• Causes:
3. In young women:
- Genetic disease, such as Turner syndrome (which leads to short
stature and lack of ovulation, normal female development and
menstruation)
- Chemotherapy or radiation
- Thyroid disorders
- Insufficient body fat
- Delayed development and lack of menstruation (amenorrhea)
18. Estrogen Imbalance
Low Level of Estrogen
Symptoms
Physical Mental
-Dry Skin -Depression
-Rapid heartbeat -Panic attacks
-Headaches -Low self esteem
-Weight gain -Mood swings
-Low back pain -Memory loss
-Difficulty concentrating
19. Estrogen Imbalance
Treatment
• Same for both high and low levels of estrogen.
1. Lifestyle Changes
- highest amount of self discipline.
2. Alternative Medicine
- extremely effective way to treat estrogen imbalance.
- Phytoestrogenic and non-phytoestrogenic
3. Hormone Replacement Therapy.
- highest risk and often the highest costs.
20. Thank You
The Sky Is NOT Your Limit
You Can Go Further To Achieve The Future.
Hinweis der Redaktion
Secondary sexual characteristic in females:BreastHip wideningincreased amounts fat in the buttock, thigh, and hip region Makes women much more hairless compare to men
Point 2Which transforms the ruptured Graafian follicle to corpus leutem which in turn secretes progesterone another important female hormone to retain pregnancy.Youthfullness = development of female
Point 1- They are released by the follicles on the ovaries and are also secreted by the corpus luteum after the egg has been released from the follicle and from the placenta.
Point 1These secondary sources are important in women who have already had their menopause.Point 2Delicate balance of estrogen is important for fertility. Excess or deficiency of this hormone affects fertility adversely.
The primary molecule that begins the synthesis of estrogen is cholesterol. It forms androstenodione. Androstenedione is a substance of moderate androgenic activity. This compound crosses the basal membrane into the surrounding granulosa cells, where it is converted to estrone or estradiol, either immediately or through testosterone.This conversion of testosterone to estradiol, and of androstenedione to estrone, is catalyzed by the enzyme aromatase. Estradiol levels vary through the menstrual cycle, with levels highest just before ovulation
It originates from the fetal adrenal gland in the form of DHEA Sulfate and then is finally transformed to Estriol in the placenta by the sulfatase enzyme.
Number 1 -High estrogen levels typically indicate a problem in the ovaries or the ovarian area.-Menstrual cycle cause hormone imbalance-Pre-menopause process (supressed progesterone production cause body to release high amount of estrogen)Number 2- Drugs (steroid medications, ampicillin)
Artherosclerosis = narrowing of artery by blood clot
Number 1- Premenstrual. ( because human do not have same metabolism, thus, varying the result of imbalance of hormone)
Lifestyle changes.-more exercise-eat more healthy food (balance diet)Alternative medicine-Herbal remedies2 type of herbs : Phytoestrogenic herbs: Containing estrogenic components produced by plants, these herbs, at first, do treat the hormonal imbalance by introducing these plant-based estrogens into the body. Non-estrogenic herbs: They don't contain any estrogen. These herbs stimulate a woman's hormone production by nourishing the pituitary and endocrine glands, causing them to more efficiently produce natural hormones. This ultimately results in balancing not only estrogen, but also progesterone and testosterone. (Safest way)Hormonal Replacement Therapy-Last choice-In form of pills. -This may be a quick and strong way to combat hormonal imbalance; but, unfortunately, it entails serious side effects and increases the risk of different types of cancer among women
