This article aims to present the great inventions that are contributing to the advancement of knowledge about the Universe throughout history represented by the telescope, the space rocket, the artificial satellite, the space capsule, the space station and the space probe, among which rovers stand out and to point out the scientific and technological advances that need to be developed to provide the conditions for humanity to colonize celestial bodies in the solar system and outside it and overcome the threats to its existence from outer space. The inventions that may occur in the future will be fundamental to enable the increase of knowledge about the Universe in order to contribute towards humanity being able to overcome the threats to its existence represented by the collision on planet Earth of bodies coming from outer space (comets, asteroids, planets of the solar system and orphan planets), by the emission of cosmic rays, especially gamma rays with the explosion of supernova stars, by the continuous distancing of the Moon in relation to the Earth, by the death of the Sun, by the collision of the Andromeda and Milky Way galaxies and by the end of the Universe.