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Infertility
Emerson Hart
Infertility
• 1 year of unprotected sex without getting
pregnant
• 6% of married women between the ages of 15
and 44
• 1.5 million women
• 28% due to male and female
• 22% just male
• 36% just female
Male Infertility
• Healthy sperm?
– Azoospermia: male has sperm, but they do not
move.
– 85% of infertility in men due to defective sperm
development.
Female Infertility
• Ovulatory dysfunction
– 40%
– Anovulation: lack of formation or release of an
egg
• Tubal disease
– Blockages, pelvic inflammatory disease,
endometriosis, scarring
• Utero-cervical factors
Female Infertility
• Obesity
– Affects menstrual cycles, amenorrhea,
anovulation, higher risks of morbidity and
miscarriage
• Amenorrhea: not going through menstruation
Couple Infertility
• Sperm killed by anti-sperm antibodies
produced by woman
• Sperm can’t swim through mucus
• As people are waiting longer to have children,
more and more fertility issues
Psychological Responses to Infertility
• Surprise, anger, denial, guilt, isolation, grief
• Wives more likely to report depression,
anxiety, stress
• Men who are infertile feel more distress and
guilt about the infertility than women who are
infertile
• Research mainly focused on females, but
males also need psychotherapeutic help
4 stages of Infertility Treatment
1. Numbness
2. Yearning
3. Disorganization and Despair
4. Reorganization
• Younger women felt more distress than older
women
• More women blame themselves for the
infertility
• 44% of women without the diagnosis still felt
responsible for the issue
• 30% of women whose partner was the one
with the diagnosis still blamed themselves for
the infertility
Treatment of Infertility
• Psychiatric intervention
– 47.1% of couples got pregnant who received
psychological therapy
– 7.1% of of control group
Treatment of Infertility
• Uterine transplant
– Successful live birth in February 2015
– Has been tried 11 times
– Transplant from 61 year old
– IVF with recipient’s egg and partner’s sperm
Treatment of Infertility
• Intracytoplasmic sperm injection
– Inject one sperm directly into the egg
– Bypasses natural barriers to fertilization
– Can lead to more children with chromosomal
abnormalities, intellectual disabilities, birth
defects, autism
Psychological Effects After Treatment
• GnRH potentially cause depression, mania,
anxiety
– 80% of women who were treated with GnRH for 4
months suffered significant depressive symptoms
Psychological Effects of Treatment
• 1/3 of men who go through infertility
treatments feel a diminished sense of
masculinity
– From reduced sperm quality mainly, not the
infertility itself
Psychological Effects to Infertility
• Less than three years, increased anxiety
• Less than one year or greater than six years
had less depression
• 20% of infertility patients report suicidal
feelings
• 13% of patients report self-harm thoughts

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Infertility Paper Presentation

  • 2. Infertility • 1 year of unprotected sex without getting pregnant • 6% of married women between the ages of 15 and 44 • 1.5 million women
  • 3. • 28% due to male and female • 22% just male • 36% just female
  • 4. Male Infertility • Healthy sperm? – Azoospermia: male has sperm, but they do not move. – 85% of infertility in men due to defective sperm development.
  • 5. Female Infertility • Ovulatory dysfunction – 40% – Anovulation: lack of formation or release of an egg • Tubal disease – Blockages, pelvic inflammatory disease, endometriosis, scarring • Utero-cervical factors
  • 6. Female Infertility • Obesity – Affects menstrual cycles, amenorrhea, anovulation, higher risks of morbidity and miscarriage • Amenorrhea: not going through menstruation
  • 7. Couple Infertility • Sperm killed by anti-sperm antibodies produced by woman • Sperm can’t swim through mucus
  • 8. • As people are waiting longer to have children, more and more fertility issues
  • 9. Psychological Responses to Infertility • Surprise, anger, denial, guilt, isolation, grief • Wives more likely to report depression, anxiety, stress • Men who are infertile feel more distress and guilt about the infertility than women who are infertile • Research mainly focused on females, but males also need psychotherapeutic help
  • 10. 4 stages of Infertility Treatment 1. Numbness 2. Yearning 3. Disorganization and Despair 4. Reorganization
  • 11. • Younger women felt more distress than older women • More women blame themselves for the infertility • 44% of women without the diagnosis still felt responsible for the issue • 30% of women whose partner was the one with the diagnosis still blamed themselves for the infertility
  • 12. Treatment of Infertility • Psychiatric intervention – 47.1% of couples got pregnant who received psychological therapy – 7.1% of of control group
  • 13. Treatment of Infertility • Uterine transplant – Successful live birth in February 2015 – Has been tried 11 times – Transplant from 61 year old – IVF with recipient’s egg and partner’s sperm
  • 14. Treatment of Infertility • Intracytoplasmic sperm injection – Inject one sperm directly into the egg – Bypasses natural barriers to fertilization – Can lead to more children with chromosomal abnormalities, intellectual disabilities, birth defects, autism
  • 15. Psychological Effects After Treatment • GnRH potentially cause depression, mania, anxiety – 80% of women who were treated with GnRH for 4 months suffered significant depressive symptoms
  • 16. Psychological Effects of Treatment • 1/3 of men who go through infertility treatments feel a diminished sense of masculinity – From reduced sperm quality mainly, not the infertility itself
  • 17. Psychological Effects to Infertility • Less than three years, increased anxiety • Less than one year or greater than six years had less depression • 20% of infertility patients report suicidal feelings • 13% of patients report self-harm thoughts