This document discusses hypertension (high blood pressure) including its causes, classification, pathogenesis, pathology, and complications. It defines hypertension as a sustained increase in blood pressure above 140/90 mmHg. Hypertension is classified as either essential (primary) in 95% of cases where the cause is unknown, or secondary in 5-10% of cases where an underlying cause like renal disease is present. Untreated hypertension can lead to damage of blood vessels and vital organs over time through mechanisms like atherosclerosis, increasing the risks of heart attack, stroke, kidney failure and retinal damage.
5. Hypertension
⢠Silent Killer â painless â complications
⢠dizziness, headache, and visual difficulties,
⢠It is the leading risk factor â MI, Stroke
⢠Responsible for the majority of emergency visits.
⢠Number one reason for drug prescription.
⢠Complications bring to diagnosis but lateâŚ
⢠Chronic, end organ & vascular damage
9. Pathological types of hypertension
The commonest type 95% Rare 5%
Usually above 40 years Younger age (25-53)
Slowly progressive Rabidly progressive
Long term (30 or more) Short fatal
10. Malignant Hypertension
⢠Rapidly progressive end organ damage.
⢠May complicate any type of HTN.
⢠Artery necrosis with thrombosis.
⢠Rapidly developing renal failure.
⢠Hypertensive encephalopathy.
⢠Left ventricular failure.
⢠less time ď No hypertrophy âŚ!
11. Pathogenesis of Renovascular HTN
GF
R
Renin
Angiotensin
II
Vasoconstrictio
n P.
Resistance
Sodium
Retention
Blood
Volume
Aldosteron
e
Hypertensio
n