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INTERVERTEBRAL DISC
PROLAPSE
PRESENTER : DR. S.H. RANNA
PGT,ORTHOPAEDICS
MODERATOR : DR. P. TAHBILDAR
PROF.&HOD
ORTHOPAEDICS
28.10.2015
HISTORY
Aurelianus (5th century) clearly
described the symptoms of SCIATICA.
 Andreas Vesalius (1543) first described
the intervertebral disc.
 Middleton & Teacher (1911) described
a case of paraplegia following
attempting to lift heavy weight from
floor on postmortem they found
fibrocartilage in extradural space.
CONT..
• Mixter and Barr (1934)
described disc herniation as
the cause of Sciatica.
 Lindblom(1948) first
described DISCOGRAPHY.
 Lyman Smith (1963)
described
CHEMONUCLEOLYSIS.
 Kambin & Gellman (1983)
reported percutaneous
approach for lumbar
discectomy.
ANATOMY OF LUMBAR SPINE
Cont..
INTERVERTEBRAL DISC
NUTRITION TO DISC
EFFECT OF AXIAL LOADING
FUNCTION OF DISC
DISC & NERVE ROOT RELATION
L5 is
TRAVERSING
NERVE ROOT
L5 is EXITING
NERVE ROOT
RELATION OF INTRADISCAL PRESSURE
AND POSTURE
CORRECT SLEEPING POSTURE
IN RELATION TO MANUAL MATERIALS
HANDLING
LUMBAR DISC PROLAPSE
DEFINITION
It is condition in
which there is
outpouching of the disc
Nucleus pulposus along
with few annular fibres
and end plate cartilage
through the tears in
annulus fibrosus into
the extradural space.
EPIDEMIOLOGY
• AGE: 30 – 40 years.
• SEX: Male affected more than female.
• MOST COMMON LEVEL: L4-L5 (next common
level is L5-S1).
• MOST COMMON TYPE: Postero-lateral type.
ETIOLOGY
MICROTROUMA
EFFECT OF SMOKING
Blood vessel get
constricted
Transport of nutrients
& disposal of waste
products decreased
Disc cells get deficient
nutrition or die
Disc degenerates &
results in DISC
INSTABILITY
STAGES OF DISC DEGENERATION
Stage of dysfunction
Stage of instability
Stage of stabilization
STAGE OF DYSFUNCTION
Episode of
rotational or
compressive trauma
(uncoordinated
muscle contraction)
Posterior facet
joint & annular
strain
Small capsular &
annular tear
occurs
Small
subluxation of
posterior joint
Posterior joint
synovium injured
& result in
SYNOVITIS
Posterior segment
muscle protect joint by
sustained hypertonic
contraction
Muscle become
ischemic &
metabolites get
accumulated cause
pain
Muscle splints the
posterior joint
subluxation
&maintained
STAGE OF INSTABILITY
Increased
dysfunction
FACET
JOINT
Degenerati
on of
cartilage
Attenuation
of capsule
Laxity of
capsule
DISC Coalescenc
e of tears
Loss of nucleus
internal
disruption
Bulging of
annulus
INCREASED
ABNORMAL
MOVEMENT
STAGE OF STABILIZATION
FACET
JOINT
Destruction
of cartilage
Fibrosis in
joint
Enlargement
of facets
Locking
facets
Fibrosis
around joint
INCREASED
STIFFNESS
STABILIZ
ATION
Fibrosis in
disc &
osteophytes
Destructio
n of plates
Approximati
on of bodies
Loss of
nucleus
DISC
PATHOPHYSIOLOGY OF PIVD
With aging, vascular channels start to fail and vascular
diffusion of nutrients decrease thus number of viable
chondrocytes in the nucleus pulposus diminishes
Synthesis rate & concentration of proteoglycans
decreases & proportion of collagen increase in
nucleus pulposus
Water binding capacity of the nucleus
decreases
Nucleus becomes more fibrous &
stiffer
CONT..
Nucleus is less able to bear & disburse load,
transferring load to the posterior annulus
ANNULU
S IN TACT
Facet joints
share even more
of the axial load
ANNULU
S FAIL
Facet joints undergo
degenerative changes &
develop osteophytes
FACET JOINT
SYNDROME
CONT…
ANNULUS FAIL
Fissures develop across
annular lamellae may
extend upto disc periphery
Internal disc
disruption cause
AXIAL PAIN
Expression of this degraded
nuclear material through
these radial fissures
DISC
HARNIATION
FATE OF DISC HARNIATION
Extrude disc & degraded nuclear material impinge
on the nerve roots
Nucleus pulposus is an immunogenic which induces
an inflammatory response mediated by TNF alpha, IL,
Phospholipase A2, Nitric oxide.
Produces radicular pain syndrome &
RADICULOPATHY
AXIAL LOCATION
• Central
(R/L)
• Subarticular
(R/L)
• Foraminal
(R/L)
• Extra
foraminal
(R/L)
SAGITAL LOCATION
• DISCAL.
• PEDICULA
—R.
• SUPRAPED
-ICULAR.
• INFRAPEDI
-CULAR.
CLINICAL FEATURE
Level of
prolapsed
T12-L1 L1—L2 L2—L3 L3—L4 L4—L5 L5—S1
Nerve
root
compres
sed
L1 L2 L3 L4 L5 S1
pain Thorac
o
lumbar
junctio
n,
groin,
proxim
al part
of thigh
Thorac
o
lumbar
junctio
n,
groin,
proxim
al part
of thigh
Upper
lumbar
spine,
anterio
r
aspect
of
proxim
al thigh
Lower
back,
hip,
postero
lateral
thigh,
anterio
r leg
Sacroili
ac joint,
hip,
lateral
thigh &
lateral
leg
Sacroiliac
joint, hip,
postero
lateral
thigh &
postero
lateral
leg to
heel
Cont..
Level of
prolapsed
T12-L1 L1-L2 L2-L3 L3-L4 L4-L5 L5-S1
Nerve
root
compress
ed
L1 L2 L3 L4 L5 S1
Paresthesi
a/Sensory
loss
Oblique
band
proximal
3rd of
thigh
anteriorly
just below
inguinal
lig.
Oblique
band mid
3rd of
thigh
anteriorly
Oblique
band
lower part
of thigh
anteriorly
just above
the knee
Medial to
shin of
tibia,
medial
aspect of
the foot
Lateral
leg,
dorsum of
foot, 1st
web space
Posterior
aspect of
thigh,
back of
calf,
lateral
side and
sole of
foot
C0NT…
Level of
prolapsed
T12-
L1
L1-L2 L2-L3 L3-L4 L4-L5 L5-S1
Nerve root
compresse
d
L1 L2 L3 L4 L5 S1
reflexes Knee jerk
slightly
diminishe
d
Knee jerk
slightly
diminishe
d
Knee jerk
diminishe
d or
absent
Changes
uncommo
n
(Posterior
tibial
reflex
diminishe
d or
absent.
Ankle jerk
absent or
diminishe
d
CONT..
STAGE OF
DEGENERATIVE
DISEASE OF DISC
STAGE OF
DYSFUNCTION
STAGE OF
INSTABILITY
STAGE OF
STABILIZATION
SYMPTOMS Low back pain often
localized or referred
to groin/ greater
trochanter/
posterior thigh
- Aggravated on
movement
- Relieved on rest
Catch in back on
movement.
- Pain on coming to
standing position
after flexion.
Low back pain
decrease in severity
SIGNS Local tenderness on
one side & at one
level
-Hypo mobility
- Extension painful
- Neurological
examination normal
Abnormal
movement of spine
- Observation of
catch
Sway or shift when
coming erect after
flexion.
Muscle tenderness
- Stiffness
- Reduced
movements
- Scoliosis
PHYSICAL EXAMINATION
• ATTITUDE: The lumbar
spine is flattened and
slightly flexed, hip
and knee slightly
flexed on the
affected side and hip
rotates forward to
relax Piriformis
GAIT
• Slow and
deliberate walk
holding their
loins with the
hands.
• TIP-TOE WALK
due to not able
to put the heel to
the floor.
SIATIC SCOLIOSIS
• Deviation of spine to one side
to take the nerve away from
the prolapsed disc is called
SCIATIC SCOLIOSIS which
becomes more obvious on
bending forwards.
• Trunk deviated to opposite
side – SHOULDER TYPE
(lateral)
• Trunk deviated to same side –
AXILLARY TYPE (medial)
CONT..
CLINICAL EXAMINATION
• SLRT– positive < 40 degree.
• Cross SLRT – May or may not +ve.
LASEGUE SIGN
BOWSTRING TEST
FEMORAL NERVE STRETCH TEST
FLIP TEST
NEGATIVE POSITIVE
DIFFERENTIAL DIAGNOSIS
INTRASPINAL CAUSES
Proximal to disc: Conus and Cauda equine lesions
(eg. Neurofibroma, ependymoma)
Disc level
• Herniated nucleus pulposus
• Stenosis (Canal or recess)
• Infection: Osteomyelitis or discitis ( with nerve
root pressure)
• Inflammation: Arachnoiditis
• Neoplasm: Benign or malignant with nerve root
pressure
CONT..
EXTRASPINAL CAUSES
Pelvis
• Gynaecological conditions
• Orthopaedic conditions ( osteoarthritis of hip,
Muscle related disease, Facet joint arthropathy)
• Sacroiliac joint disease
• Neoplasm
Peripheral nerve lesions
• Neuropathy (Diabetic, tumour, alcohol)
• Local sciatic nerve conditions (Trauma, tumour)
• Inflammation (herpes zoster)
KEY DIAGNOSTIC POINTS
LUMBAR DISC PROLAPSE
 Leg pain greater than back pain
 Neurological deficit present
ANNULAR TEARS
 Back pain greater than leg pain
 Bilateral SLRT positive
FACET JOINT ARTHROPATHY
 Localized tenderness present unilaterally over joint
 Pain occurs immediately on spinal extension
 Pain exacerbated with ipsilateral side bending
CONT..
SPINAL STENOSIS
Back and/or leg pain develops after walks a
limited distance.
Flexion relieves symptoms
MYOGENIC OR MUSCLE RELATED
Pain localised to affected muscle
Pain increases on prolonged muscle use
Pain reproduced with sustained muscle
contraction against resistance
Contralateral pain with side bending
INVESTIGATIONS
•THE CORNERSTONE OF
DIAGNOSIS OF LUMBAR
DISC DISEASE IS THE
HISTORY AND PHYSICAL
EXAMINATION NOT THE
INVESTIGTION.
PLAIN RADIOGRAPHY
• Narrowing of disc space
• Osteophytes formation
along the peripheries of
the adjacent vertebral
bodies
• Sclerosis or condensation
of subchondral bone of the
adjacent vertebral bodies
above and below the
affected disc
• Loss of lumbar lordosis
• Translation of vertebral
bodies.
MYELOGRAPHY
CT SCAN
• ADVANTAGES
• highly accurate & noninvasive tool.
• superior imaging of cortical and trabecular bone.
• identify root compressive lesions such as disc
herniation.
• differentiate between bony osteophyte from soft
disc.
• to diagnose foraminal encroachment of disc
material
LIMITATION OF CT SCAN
• It cannot differentiate
between scar tissue
and new disc
herniation
• It does not have
sufficient soft tissue
resolution to allow
differentiation
between annulus and
nucleus.
MRI OF SPINE
• It allows direct
visualization of
herniated disc
material and its
relationship to
neural tissue
including
intrathecal
contents.
CONT..
TREATMENT
•CONSERVATIVE
•SURGICAL
CONSERVATIVE
• Majority of disc prolapse
respond well to conservative
therapy. Resolution of first
disc prolapse takes place
approximately 95% of patients
over a period of 3 months.
BED REST
DRUGS
• NSAIDS
• SOME MUSCLE RELAXANTS
• MOOD ELEVATORS & ANTI ANXIETY
DRUGS
• ETC…
PHYSIOTHERAPY
• TENS &IFT THERAPY
CONT..
EXTENSION CONTROL
KNEE ROLLS
Surgical treatment
GOAL-
To relive neural compression .
and hence radiculopathy
while minimizing
complications.
INDICATIONS
ABSOLUTE
• Bladder and bowel involvement: The cauda equine
syndrome
• Increasing neurological deficit
RELATIVE
• Failure of conservative treatment
• Recurrent sciatica
• Significant neurological deficit with significant SLR
reduction
• Disc rupture into a stenotic canal
• Recurrent neurological deficit
CONTRAINDICATIONS FOR SURGERY
• Wrong patient ( poor potency for recovery)
• Wrong diagnosis
• Wrong level
• Painless HNP (do not operate for primary
complaint of weakness or paresthesia, in the
absence of pain)
• Inexperienced surgeon applying poor technical
skills
• Lack of adequate instruments
SOME OPERATIONS..
• HEMI OR PARTIAL LAMINECTOMY
• FENESTRATION
• TOTAL LAMINECTOMY
• LAMINOTOMY & DISCECTOMY
FAILED BACK SYNDROME
It is a condition characterized by persistent
postoperative backache and sciatica.
VERY COMMON CAUSES
• Recurrent/ Persistent disc material at
operated site
• Herniated Nucleus Pulposus at other site
• Epidural scar / Fibrosis
• Facet arthrosis / Spinal stenosis
THANK YOU…

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Intervertebral disc prolapese

  • 1. INTERVERTEBRAL DISC PROLAPSE PRESENTER : DR. S.H. RANNA PGT,ORTHOPAEDICS MODERATOR : DR. P. TAHBILDAR PROF.&HOD ORTHOPAEDICS 28.10.2015
  • 2. HISTORY Aurelianus (5th century) clearly described the symptoms of SCIATICA.  Andreas Vesalius (1543) first described the intervertebral disc.  Middleton & Teacher (1911) described a case of paraplegia following attempting to lift heavy weight from floor on postmortem they found fibrocartilage in extradural space.
  • 3. CONT.. • Mixter and Barr (1934) described disc herniation as the cause of Sciatica.  Lindblom(1948) first described DISCOGRAPHY.  Lyman Smith (1963) described CHEMONUCLEOLYSIS.  Kambin & Gellman (1983) reported percutaneous approach for lumbar discectomy.
  • 8. EFFECT OF AXIAL LOADING
  • 10. DISC & NERVE ROOT RELATION L5 is TRAVERSING NERVE ROOT L5 is EXITING NERVE ROOT
  • 11. RELATION OF INTRADISCAL PRESSURE AND POSTURE
  • 13. IN RELATION TO MANUAL MATERIALS HANDLING
  • 14. LUMBAR DISC PROLAPSE DEFINITION It is condition in which there is outpouching of the disc Nucleus pulposus along with few annular fibres and end plate cartilage through the tears in annulus fibrosus into the extradural space.
  • 15. EPIDEMIOLOGY • AGE: 30 – 40 years. • SEX: Male affected more than female. • MOST COMMON LEVEL: L4-L5 (next common level is L5-S1). • MOST COMMON TYPE: Postero-lateral type.
  • 18. EFFECT OF SMOKING Blood vessel get constricted Transport of nutrients & disposal of waste products decreased Disc cells get deficient nutrition or die Disc degenerates & results in DISC INSTABILITY
  • 19. STAGES OF DISC DEGENERATION Stage of dysfunction Stage of instability Stage of stabilization
  • 20. STAGE OF DYSFUNCTION Episode of rotational or compressive trauma (uncoordinated muscle contraction) Posterior facet joint & annular strain Small capsular & annular tear occurs Small subluxation of posterior joint Posterior joint synovium injured & result in SYNOVITIS Posterior segment muscle protect joint by sustained hypertonic contraction Muscle become ischemic & metabolites get accumulated cause pain Muscle splints the posterior joint subluxation &maintained
  • 21. STAGE OF INSTABILITY Increased dysfunction FACET JOINT Degenerati on of cartilage Attenuation of capsule Laxity of capsule DISC Coalescenc e of tears Loss of nucleus internal disruption Bulging of annulus INCREASED ABNORMAL MOVEMENT
  • 22. STAGE OF STABILIZATION FACET JOINT Destruction of cartilage Fibrosis in joint Enlargement of facets Locking facets Fibrosis around joint INCREASED STIFFNESS STABILIZ ATION Fibrosis in disc & osteophytes Destructio n of plates Approximati on of bodies Loss of nucleus DISC
  • 23. PATHOPHYSIOLOGY OF PIVD With aging, vascular channels start to fail and vascular diffusion of nutrients decrease thus number of viable chondrocytes in the nucleus pulposus diminishes Synthesis rate & concentration of proteoglycans decreases & proportion of collagen increase in nucleus pulposus Water binding capacity of the nucleus decreases Nucleus becomes more fibrous & stiffer
  • 24. CONT.. Nucleus is less able to bear & disburse load, transferring load to the posterior annulus ANNULU S IN TACT Facet joints share even more of the axial load ANNULU S FAIL Facet joints undergo degenerative changes & develop osteophytes FACET JOINT SYNDROME
  • 25. CONT… ANNULUS FAIL Fissures develop across annular lamellae may extend upto disc periphery Internal disc disruption cause AXIAL PAIN Expression of this degraded nuclear material through these radial fissures DISC HARNIATION
  • 26. FATE OF DISC HARNIATION Extrude disc & degraded nuclear material impinge on the nerve roots Nucleus pulposus is an immunogenic which induces an inflammatory response mediated by TNF alpha, IL, Phospholipase A2, Nitric oxide. Produces radicular pain syndrome & RADICULOPATHY
  • 27.
  • 28. AXIAL LOCATION • Central (R/L) • Subarticular (R/L) • Foraminal (R/L) • Extra foraminal (R/L)
  • 29. SAGITAL LOCATION • DISCAL. • PEDICULA —R. • SUPRAPED -ICULAR. • INFRAPEDI -CULAR.
  • 30. CLINICAL FEATURE Level of prolapsed T12-L1 L1—L2 L2—L3 L3—L4 L4—L5 L5—S1 Nerve root compres sed L1 L2 L3 L4 L5 S1 pain Thorac o lumbar junctio n, groin, proxim al part of thigh Thorac o lumbar junctio n, groin, proxim al part of thigh Upper lumbar spine, anterio r aspect of proxim al thigh Lower back, hip, postero lateral thigh, anterio r leg Sacroili ac joint, hip, lateral thigh & lateral leg Sacroiliac joint, hip, postero lateral thigh & postero lateral leg to heel
  • 31. Cont.. Level of prolapsed T12-L1 L1-L2 L2-L3 L3-L4 L4-L5 L5-S1 Nerve root compress ed L1 L2 L3 L4 L5 S1 Paresthesi a/Sensory loss Oblique band proximal 3rd of thigh anteriorly just below inguinal lig. Oblique band mid 3rd of thigh anteriorly Oblique band lower part of thigh anteriorly just above the knee Medial to shin of tibia, medial aspect of the foot Lateral leg, dorsum of foot, 1st web space Posterior aspect of thigh, back of calf, lateral side and sole of foot
  • 32. C0NT… Level of prolapsed T12- L1 L1-L2 L2-L3 L3-L4 L4-L5 L5-S1 Nerve root compresse d L1 L2 L3 L4 L5 S1 reflexes Knee jerk slightly diminishe d Knee jerk slightly diminishe d Knee jerk diminishe d or absent Changes uncommo n (Posterior tibial reflex diminishe d or absent. Ankle jerk absent or diminishe d
  • 33. CONT.. STAGE OF DEGENERATIVE DISEASE OF DISC STAGE OF DYSFUNCTION STAGE OF INSTABILITY STAGE OF STABILIZATION SYMPTOMS Low back pain often localized or referred to groin/ greater trochanter/ posterior thigh - Aggravated on movement - Relieved on rest Catch in back on movement. - Pain on coming to standing position after flexion. Low back pain decrease in severity SIGNS Local tenderness on one side & at one level -Hypo mobility - Extension painful - Neurological examination normal Abnormal movement of spine - Observation of catch Sway or shift when coming erect after flexion. Muscle tenderness - Stiffness - Reduced movements - Scoliosis
  • 34. PHYSICAL EXAMINATION • ATTITUDE: The lumbar spine is flattened and slightly flexed, hip and knee slightly flexed on the affected side and hip rotates forward to relax Piriformis
  • 35. GAIT • Slow and deliberate walk holding their loins with the hands. • TIP-TOE WALK due to not able to put the heel to the floor.
  • 36. SIATIC SCOLIOSIS • Deviation of spine to one side to take the nerve away from the prolapsed disc is called SCIATIC SCOLIOSIS which becomes more obvious on bending forwards. • Trunk deviated to opposite side – SHOULDER TYPE (lateral) • Trunk deviated to same side – AXILLARY TYPE (medial)
  • 38. CLINICAL EXAMINATION • SLRT– positive < 40 degree. • Cross SLRT – May or may not +ve.
  • 43. DIFFERENTIAL DIAGNOSIS INTRASPINAL CAUSES Proximal to disc: Conus and Cauda equine lesions (eg. Neurofibroma, ependymoma) Disc level • Herniated nucleus pulposus • Stenosis (Canal or recess) • Infection: Osteomyelitis or discitis ( with nerve root pressure) • Inflammation: Arachnoiditis • Neoplasm: Benign or malignant with nerve root pressure
  • 44. CONT.. EXTRASPINAL CAUSES Pelvis • Gynaecological conditions • Orthopaedic conditions ( osteoarthritis of hip, Muscle related disease, Facet joint arthropathy) • Sacroiliac joint disease • Neoplasm Peripheral nerve lesions • Neuropathy (Diabetic, tumour, alcohol) • Local sciatic nerve conditions (Trauma, tumour) • Inflammation (herpes zoster)
  • 45. KEY DIAGNOSTIC POINTS LUMBAR DISC PROLAPSE  Leg pain greater than back pain  Neurological deficit present ANNULAR TEARS  Back pain greater than leg pain  Bilateral SLRT positive FACET JOINT ARTHROPATHY  Localized tenderness present unilaterally over joint  Pain occurs immediately on spinal extension  Pain exacerbated with ipsilateral side bending
  • 46. CONT.. SPINAL STENOSIS Back and/or leg pain develops after walks a limited distance. Flexion relieves symptoms MYOGENIC OR MUSCLE RELATED Pain localised to affected muscle Pain increases on prolonged muscle use Pain reproduced with sustained muscle contraction against resistance Contralateral pain with side bending
  • 47. INVESTIGATIONS •THE CORNERSTONE OF DIAGNOSIS OF LUMBAR DISC DISEASE IS THE HISTORY AND PHYSICAL EXAMINATION NOT THE INVESTIGTION.
  • 48. PLAIN RADIOGRAPHY • Narrowing of disc space • Osteophytes formation along the peripheries of the adjacent vertebral bodies • Sclerosis or condensation of subchondral bone of the adjacent vertebral bodies above and below the affected disc • Loss of lumbar lordosis • Translation of vertebral bodies.
  • 50. CT SCAN • ADVANTAGES • highly accurate & noninvasive tool. • superior imaging of cortical and trabecular bone. • identify root compressive lesions such as disc herniation. • differentiate between bony osteophyte from soft disc. • to diagnose foraminal encroachment of disc material
  • 51. LIMITATION OF CT SCAN • It cannot differentiate between scar tissue and new disc herniation • It does not have sufficient soft tissue resolution to allow differentiation between annulus and nucleus.
  • 52. MRI OF SPINE • It allows direct visualization of herniated disc material and its relationship to neural tissue including intrathecal contents.
  • 55. CONSERVATIVE • Majority of disc prolapse respond well to conservative therapy. Resolution of first disc prolapse takes place approximately 95% of patients over a period of 3 months.
  • 57. DRUGS • NSAIDS • SOME MUSCLE RELAXANTS • MOOD ELEVATORS & ANTI ANXIETY DRUGS • ETC…
  • 60. Surgical treatment GOAL- To relive neural compression . and hence radiculopathy while minimizing complications.
  • 61. INDICATIONS ABSOLUTE • Bladder and bowel involvement: The cauda equine syndrome • Increasing neurological deficit RELATIVE • Failure of conservative treatment • Recurrent sciatica • Significant neurological deficit with significant SLR reduction • Disc rupture into a stenotic canal • Recurrent neurological deficit
  • 62. CONTRAINDICATIONS FOR SURGERY • Wrong patient ( poor potency for recovery) • Wrong diagnosis • Wrong level • Painless HNP (do not operate for primary complaint of weakness or paresthesia, in the absence of pain) • Inexperienced surgeon applying poor technical skills • Lack of adequate instruments
  • 63. SOME OPERATIONS.. • HEMI OR PARTIAL LAMINECTOMY • FENESTRATION • TOTAL LAMINECTOMY • LAMINOTOMY & DISCECTOMY
  • 64. FAILED BACK SYNDROME It is a condition characterized by persistent postoperative backache and sciatica. VERY COMMON CAUSES • Recurrent/ Persistent disc material at operated site • Herniated Nucleus Pulposus at other site • Epidural scar / Fibrosis • Facet arthrosis / Spinal stenosis