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1. Brand Name : Albutrix 100 / 300 / 500
Keto-analogues and essential aminoacids food / dietary supplements in the
management of chronic kidney disease.
Essential aminoacids as food supplements / dietary supplements for the
management of Chronic kidney disease(CKD) is increasingly common, and there is
an increasing awareness thatevery strategy should beused to avoid complications
of CKD. Restriction of dietary protein intake has been a relevant part of the
management of CKD for morethan 100 years, buteven today, the principal goal of
protein-restricted regimens is to decrease the accumulation of nitrogen waste
products, hydrogen ions, phosphates, and inorganic ions while maintaining an
adequate nutritional status to avoid secondary problems such as metabolic
acidosis, bone disease, and insulin resistance, as well as proteinuria and
deterioration of renal function. This supplement focuses on recent experimental
and clinical findings related to an optimized dietary management of predialysis,
dialysis, and transplanted patients as an important aspect of patient care.
Nutritional treatment strategies are linked toward ameliorating metabolic and
endocrine disturbances, improving/maintaining nutritional status, as well as
delaying the renal replacement initiation and improving outcomes in CKD patients.
A final consensus states thatdietary manipulations should be considered as one of
the main approaches in the management program of CKD patients.
The manipulation of dietary protein intake is the mainstay of nutritional treatment
of patients affected by chronic renal insufficiency, with the aim to reduce the

2. burden of uremic toxins in orderto decreaseuremic toxicity and delay the need for
dialysis. Consensus exists regarding the benefit of progressive protein restriction
towardsdelayingthe progressionofrenalfailure andthe need fordialysis,provided
adequate energy supply. Although pivotal, protein restriction is only one aspect of
the dietary management of chronic kidney disease (CKD) patients. Additional
features, though strictly related to proteins, include modifications in sodium,
phosphorus and energy intake, as well as in the source(animal or plant derived) of
protein and lipids. In addition, supplements play an important role as a means to
obtain both beneficial effects and nutritional safety in the renal patient. Essential
amino acid and ketoacid mixtures are the most utilized types of supplementation
in CKD patients on restricted protein regimens. The essential amino acids plus
ketoacid supplementation is mandatoryin conjunction with a verylow-protein diet
in order to assurean adequate essential amino acid supply. It is needed to safely
implement a very low protein (and phosphorus) intake, to obtain the beneficial
effect of a severe protein restriction while preventing malnutrition. Protein-free
products and energy supplements are also crucial for the prevention of protein-
energy wasting in CKD patients.