Ayurveda strongly believes in using drugs with particular tastes in treating diseases. This presentation will help you understand the basics of rasa and its applied aspects in planning treatment protocol.
3. 6. ACTIONS
On doshas
On dhatus
On malas
On agni
On srotas
General systemic action
7. ORDER OF ADMINISTRATION
8. SEASONAL PREDOMINANCE
In medicine
In diet
3
4. 9. RASA ROOPANTARA
10. RASA NIVRUTHI AND VISHESHA
11. RASOPALABDHI
12. TARATAMA BHAVA OF RASA wrt GUNA
13. INDICATIONS AND CONTRAINDICATIONS
14. IDEAL DIET
15. SHADRASA IN PRACTICAL USE – IN DINACHARYA,RUTUCHARYA
16. TASTE – MODERN VIEW- RESEARCH CORNER
17. TASTE DETECTION TOOL
18. CONCLUSION
4
5. Rasa comes under the five concepts of a substance (Rasapanchakas) namely,
rasa (taste),
guna (properties),
virya (potency),
vipaka (metabolic after product of rasa) and
prabhava (specific pharmacological effect)
• द्रव्ये रसो गुणं वीयं ववपाकःशक्तिरेव च |
पदाराथःपञ्चतिष्ठक्ति स्वं स्वं क
ु वथक्ति कर्थ च || (भा. प्र)
• दव्यरसगुणवीयथववपाकतिमर्त्ते च क्षयवृद्धि दोषाणार् ्साम्यं च | (सु. सू)
5
6. It determines and explains the pharmacological behaviour of a substance
These five principles are manifestations of five mahābhūtas in specific states of
activation.
Therefore, these ( only rasa ) principles do indicate the structural composition and
consequent activity of any substance.
Therefore the predominant proto elements in a drug can sometimes be predicted from
its taste and thus can infer how the drug will act.
6
7. Though we find scattered references of rasa throughout the samhitas, there are
special chapters dedicated to rasa owing to its significance in the treatment
aspect.
Rasa vimanam adhyaya (Ch./Vi/1)
Rasa vishesha vijnaaneeyam adhyaya (Su/Soo/42)
Rasa bhedeeyam adhyaya (A.H. /Su/ 10)
7
8. रस आस्वादिे ।। (वाचस्पत्यं)
Rasa is something experienced by an individual while
tasting a dravya.
8
9. रसिारो रस: । (च.सु)
रस्यिे आस्वाद्यिे इति रसः। (चक्रपाणण)
रसिेक्तद्रय ग्राह्यो यो अरथ: स रस: । (र.वै)
That which is perceived by rasanendriya (tongue-taste
sense organ).
Rasa is an important quality manifested at the level of
tongue and is one among pharmacologically active
principle or quality which is directly perceivable.
9
10. Enumeration of rasa
Enumeration according to different acharyas – Charaka Sootra
Rasa kalpana
10
11. A seminar was organised by Punarvasu Atreya regarding the determination of
number of rasas. After considering various views expressed by different rishis, it
was concluded by Atreya that the rasas are only six. They are :
Madhura Ksheera,
Draksha
Amla Changeri,
Jambeera
Lavana Saindhava lavana, Samudra
lavana
Katu Pippali,
Maricha
Tikta Kiratatikta,
Chandana
Kashaya Khadira,
Haritaki
11
14. According to Indu,
“Kalasya samvatsarakyasya shat rtukatvat rasasyapi
shatbhedatvam”
According to Chakrapani and Arunadutta - Due to
svabhava
14
15. Eka rasa - 6
Dwi rasa - 15
Tri rasa - 20
Chatushka - 15
Panca rasa - 6
Shad rasa - 1
Total - 63
(CH. SU/26)
15
16. Single rasa virechana aushadha is ahrudya.
So always combination of different rasa aushadha is used.
e.g. In Only Vataja Vikara – Madhuraa rasa is used
In Pittayukta Vata – Madhura potentiated with Tikta
rasa
In Kaphayukta Vata – Amla and Katu rasa in
combination
16
20. Pharmacological basis of drug action revolves around the universal
pharmacological principle that similar structures have similar pharmacological
activity.
Conversely, if the structure of a substance is known, then its pharmacological
behavior can be inferred.
Conventional pharmacology uses chemical structure as the basis for
pharmacological action of the drug.
Ayurveda uses Pañcamahābhūta theory as the fundamental basis of drug action.
20
21. A set of properties and actions is attributed to each of these mahābhūtas, one or some
or all of which can be manifested in a substance when the mahābhūtas are present in
a state of activation.
Mere presence of mahābhūta will not lead to the manifestation of properties and
actions, but the utkarṣa of mahābhūtas is fundamental to the expression of
properties and actions.
For example, if a substance produces heaviness in the body, then it is understood
that pṛthvī mahābhūta is present in an activated state in it.
21
29. RASA CHARACTERSTIC FEATURES
MADHURA PLEASANT, SOFTENING, ANOINTING, ATTRACTS ANTS AND BEES
AMLA • CAUSES SALIVATION, SWEATING, MOUTH CLEANSING
• IS AN APPETISER
LAVANA • EASILY SOLUBLE
• WATER RETAINING, SOFTENING
• IS AN APPETISER
• BURNING SENSATION IN MOUTH AND THROAT
KATU CAUSES SALIVATION, LACRIMATION, TINGLING SENSATION
TIKTA • OVERSHADOWS ALL OTHER TASTES
• APPETISER AND MOUTH CLEANSER
• PRODUCES DRYNESS OF THE MOUTH
KASHAYA • PRODUCES CLARITY OF MOUTH
• CAUSES DRYNESS, STIFFNESS
• CAUSES HEAVINESS AND PAIN IN THE CARDIAC REGION
29
31. These characters of the tastes can be applied in the clinical practice with a wide spectrum
of utility.
For eg.-Taking salivation (aasya samsravana) as an objective indicator, six rasas may be
divided into 3 groups:
Action on Saliva Rasa of therapeutic use (taste)
a. sialogogues ( increasing salivary secretion) - in
xerostomia / caries
• Amla
• Katu
b. anti-sialogogues (decreasing salivary
secretion)- in hypersalivation
• Tikta
• Kashaya
c. altering consistency of saliva • Madhura
• Lavana
31
35. Consideration of 6 gunas in relation to 6 rasas is very important from applied point of view.
they are the active properties applicable in respective six therapeutic measures
(shatkarmas)
KARMA GUNA RASA
Brmhana Guru Madhura
Langhana Laghu Katu
Swedana Ushna
Stambhana Sheeta
Rukshana Ruksha
Snehana Snigdha
35
36. Keeping these gunas in view rasas can be applied in treatment of diseases
Madhura rasa can be used is karshya so as to bring in gurutwa in the body.
Amla rasa is used in conditions of agnimandya, for amapaachana pertaining to its
ushna guna.
Lavana rasa can be utilized in Pakwashaya gata vata due to its ushna guna in taming
vata.
Katu may be useful in udara due to its rooksha ushna guna.
Tikta is beneficial for Amlapitta as it does rookshana of aggravated pitta.
Kashaya is good in Atisara as it brings stambhana.
36
38. दव्यरसगुणवीयथववपाकतिमर्त्ते च क्षयवृद्धि दोषाणार् ्साम्यं च | (सु. सू)
ON DOSHAS ि एिे रसा: स्वयोतिविथिा, अतययोतिप्रशर्िा च । (सु. सू.४२/६)
RASA EFFECT ON VATA EFFECT ON PITTA EFFECT ON
KAPHA
MADHURA
AMLA
LAVANA
KATU
TIKTA
KASHAYA
38
39. 2. ON DHATUS
Madhura – Anabolic activity- increase in dhatus – ojavardhana, stanyajanana, varnya,
keshya
Amla – though stimulates such activities by improving agni, has a decreasing effect on
shukra- henceforth not a tonic.
Lavana- increases water content, causes laxity in the body (sarva shareera avayavaan
mrudu karoti)
Katu - Catabolic activity, scrapes away unwanted muscular structures (mamsa
vilekhana), breaks coagulatory pathways (shonita sanghatam bhinnathi), reduces stanya,
sukra, meda
Tikta - Catabolic activity, scrapes away kleda,meda,vasa,majja,sweda,lasika,mootra and
helps in stanyashodhana.
Kashaya - Catabolic activity, blood purification (asravishodhana), kleda meda
vishoshanam
39
40. Tikta rasa has an absorbing effect and decreases meda, vasa,
majja, lasika which are pathogenic factors of prameha
(saptako..)
Tikta is an important rasa useful in the treatment of
prameha.
40
41. 3. ON MALAS
Rasas predominant of paarthivapya gunas- Madhura, Amla, Lavana are laxative, diuretic
and carminative.
Katu – helps in elimination of waste products (kleda malaan upahanti)
Kashaya- Constipative, anti-diuretic and causes obstruction of flatus
Tikta - Dries up malas (Vinmootra Upashoshana)
41
42. Kashaya rasa is the best for stambhana and can be
utilized in the treatment of diarrhoea, polyuria,
haemorrhages etc.
42
43. 3. ON AGNI
Agneya rasas- Katu, Amla, Lavana – appetisers and digestives
(dipana and paachana)
Tikta – though Soumya- stimulates agni by promoting samana vata
and absorbs kapha responsible for mandagni.
Madhura and Kashaya has an opposite effect to agni (agni sadaka).
43
44. Madhura rasa being agni sadaka, can be utilized in
bulimia.
Amla rasa can be utilized in loss of appetite and taste
disorders
44
45. 4. ON SROTAS
Katu, tikta, lavana are srotoshodhaka (channel- cleaning)
Katu – Vayavyaagneya guna- margaan vivrunothi - absorbs fluid and expels
obstructive materials – pramaathi – as opposed to abhisyandi (channel-
obstructing)
Tikta acts in a similar way by absorbing the fluid due to vata and vacates the
space on account of akasha. Due to sookshma guna it permeates even to
minutest channels.
Lavana – liquifies the solid mass and expels it due to tikshna guna but has no
absorbing property.
Madhura, Amla, Kashaya may precipitate srotorodha , can be called as sroto
upalepaka.
45
46. Lavana- liquifies the solid mass and expels it due to tikshna guna, it can
penetrate even minutest channel.
Example - Lavana abhyanga in swasa rogi, in vasthi karma
Amla- acidic foods enhances iron absorption (ferric to ferrous- stable to unstable) –
increases bioavailability –
Example -Mandooravataka anupana with thakra, lime juice
46
48. IN MEDICINE
In treatment of diseases rasa should be used
in a definite order acc. to dosha as follows:
IN DIET
• In meals one should start with Madhura,
Amla, Lavana and finish with Katu,
Tikta, Kashaya. But if the food is
excessively spicy, the meal should end
with madhura. (B.P)
DOSA 1ST 2ND 3RD
VATA LAVANA AMLA MADHUR
A
PITTA TIKTA MADHUR
A
KASHAYA
KAPHA KATU TIKTA KASHAYA
1ST 2ND 3RD
MADHUR
A
AMLA-
LAVANA
KATU-TIKTA-
KASHAYA
48
52. रसो तिपािे द्रव्याणां । (च.सु)
प्रत्यक्षिो अिुर्ािाि् उपदेशिश्च रसािार्ुपलक्ब्ि॥ (र.वै)
EXAMPLES
Prathyaksha- Sweetness of sugar
Anumana- Sweetness of urine in Diabetes
Upadesa- Sweetness of Suvarna, astringency of Madhu
52
53. RASA DISEASE INDICATIONS
MADHURA General debility, Geriatric conditions, Habitual abortion, Deficiency of
breast milk
AMLA Loss of appetite, Dyspepsia
LAVANA Loss of appetite , Dyspepsia, as Diuretic
KATU Loss of appetite, Indigestion, Obesity, Diabetes, Cough asthma, Skin
diseases
TIKTA Loss of appetite, Dyspepsia, Worms, Gastritis, Jaundice, Skin diseases,
Fever, Obesity, Diabetes, Excessive discharges, pus etc
KASHAYA Diarrhoea, Haemorrhage, Wounds, Polyuria, Respiratory Disorders
53
54. RASA DISEASE INDICATIONS
MADHURA Cough, Asthma, Diabetes, Goitre etc
AMLA Gastritis, Internal haemorrhage, Jaundice
LAVANA Skin diseases, Swelling, Ascites, Hypertension, Haemorrhage, Gastritis etc
KATU Semen disorders, Retension of urine
TIKTA Disorders of vata, Semen deficiency
KASHAYA General debility, Disorders of vata, Loss of appetite
54
55. A diet comprising of all the six rasas is said to be ideal one- indicating that all the
components required for a living system can be incorporated under the 6 rasas.
1st 3 tastes - अभ्यवहरणाय पूक्ििं – madhura, amla, lavana
षड्सु एवं युतिं वर्िं षड्सु युतिं ववरेचिं ।
षड्सु आस्रापिं युतिं षड्सु संशर्िं हहिं ॥ (र.वै)
55
57. Danthadhavana vidhi by Kashaya Katu Tikta
dravya like Nyagrodha, Khadira, Karanja
Udvartana for Medoghna and Twakprasadana
action by Katu Tikta Kashaya drugs
Dhumapana in Kapha – Vata vrudha avastha by
Katu Tikta Kashaya rasa dravya
57
58. Hemanta, sisira – for nourishment- Madhura, Amla,
Lavana
Varsha - for the maintainance of Agni- Amla, Lavana
Vasantha - to pacify the moisture - Tikta, Katu, Kashaya
Greeshma - to counteract the dryness -Madhura
Sarat - to bring pitta in balance - Madhura, Tikta,
Kashaya
58
60. Primary tastes
Sites of perception
Taste buds and Gustatory Papillae
Nervous innervations to tongue
Gustatory pathway
Taste – significance in modern view
60
61. Taste is a form of chemoreception which occurs in the specialized taste receptors in the mouth.
RASA Comprises of Receptor
SWEE
T
Sugars and proteins, aldehydes and
ketones.
G- Protein Coupled Receptor (GPCR)
SOUR Acids (H+ ions conc.) Type III taste receptor cell
SALT Ionised salts (cations like Na+/ K+/
Li+ )
Sodium chloride receptor
BITTE
R
Long chain organic substances
containing nitrogen and alkaloid
Type II taste receptor cell (TAS2R)
UMAM
I
L-Glutamate (amino acid), found in
fermented foods
G- protein Coupled Glutamate
Receptor
61
There are recent researches on a newly invented taste – the Fat taste – with potential
CD36 receptor.
63. Taste buds contain the taste receptor
cells, which are also known as gustatory
cells.
Taste buds exist primarily in the small
bumps on your tongue, called papillae.
They also are present in other parts of the
mouth, like the palate and throat.
Taste buds develop in utero and
scientists believe they are functional by
10 to 13 weeks of gestation. Fetuses are
able to taste foods in the maternal diet
that pass through the amniotic fluid.
Tastes of the maternal diet are also
detected in breast milk.
63
64. Each receptor cell
lives for 1-2
weeks.
Each receptor in a
taste bud
responds best to
one of the tastes.
64
65. There are four types of papillae:
• Filiform: The most common, covering the tough surface of the tongue, and do not
contain taste buds
• Fungiform: Located near the front of the tongue
• Circumvallate: Located near the back of the tongue
• Foliate: Located on the sides of the tongue
65
66. There are mainly 2 cranial nerves that innervate the tongue for taste
o Facial nerve (ant 2/3)
o Glossopharyngeal nerve (post 1/3)
Vagus nerve also contributes to taste perception from very little posteriormost
part of the mouth.
66
68. Patients with Addison's disease, pituitary insufficiency, or cystic fibrosis
sometimes have a hyper-sensitivity to the five primary tastes.
Disorders of taste
Ageusia (complete loss of taste)
Hypogeusia (reduced sense of taste)
Dysgeusia(distortion in sense of taste)
Parageusia (persistent abnormal taste)
Hypergeusia (abnormally heightened sense of taste)
68
69. Prof. P. V. Sharma has attempted to evolve a methodology for Objective
Determination of rasa.
RASA CONSTITUENTS
MADHURA PROTIENS, CARBOHYDRATES, VEGETABLE FATS
AMLA ACIDIC NATURE
LAVANA PRESENCE OF SODIUM CHLORIDE WITH A SALTISH
TASTE
KATU ESSENTIAL OILS, PHENOL
TIKTA ALKALOIDS, GLYCOSIDES
KASHAYA TANNIN, ASTRINGENT NATURE
69
70. TASTE-DETECTION TOOLS
Blind method
Dilution method-Taste threshold-minimum quantity of a substance
required to stimulate the taste buds.
The order of rasas on the basis of maximum intensity is
Tikta – showed very high taste threshold
Madhura
Amla
Kashaya
Katu
Lavana
Prof. C. Dwarakanath suggested one method namely TTT (Taste Threshold
Test) for Quantitative Determination of rasa
Electronic tongue- It is an instrument that measures and compares tastes.
70
71. Rasa is the visesha guna of rasanendriya.
Health or disease is known by certain normal and abnormal functions of
doshas in body. It can be normalised by giving drugs which are of opposite
attributes to that dosha in its panchabhootha constitution.
The easiest and most practical way to infer the predominant mahabhootha
in a subject is rasa.
The action of a drug is decided by rasapanchaka. Being the first rasa gives
instant action.
When particular body constituent decreases, there is a desire for
substances with specific taste to balance it.
During the samprapti of a disease, patient express like/dislike for
particular rasa as per state of dosha.
Rasa plays important role in swasthavrutta and in treatment aspect.
71
72. Rasa in swastavrutta can be understood by its application in dinacharya and
rutucharya.
Rasa in treatmental aspect can be understood by 2 aspects:
o Nidana parivarjana of specific rasas in specific conditions eg: Kashaya rasa in
vibandha
o Treatments in srotodushti are treated specifically by certain rasas eg: Tikta rasa
in asthivaha srotas, Madhura Tikta rasa in Majjavaha srotas.
Dravya vargeekarana can be done on the basis of rasa – e.g. Madhura skandha,
Tikta skandha etc.
Nomenclature of certain dravya are given on the basis of name of rasa itself
e.g. Chitraka- Ushana(katu), Lanka-Katuveera.
72
73. यः स्याद्रसववकल्पज्ञः स्याच्च दोषववकल्पववि्।
ि स र्ुह्येि् ववकाराणां हेिुमलङ्गोपशाक्तिषु॥
च. सू. 26/ 27
A physician, well acquainted with combination of rasas and doshas, seldom commits
blunders in ascertaining the etiology, symptoms and treatment of diseases.
73
Karma of dravya is accomplished by rasapanchaka.
Rasa (taste) - Raso nipaate dravyanam. [2] when a substance is brought into touch with the Rasanendriya (or tongue), then the taste will be known.
Guna (predicament) - Samvayi tu nischesta karanam gunah. [3] i.e, guna as the character or property which will remain in a dravya with inherent relationship and is devoid of action.
Vipaka (post-digestive taste) - Vishistha jarananishtha kale rasa visheshasaya pakah pradurbhavah vipakah. [4] The end product of a dravya which is the outcome of digestion is known as Vipaka. Vipaka is the bio-transformative phase of rasa.
Virya (potency) - Vishishtha samrathya sampanna guna, i.e, Potent and efficient most factor which is called as virya that is bio- energy. [5]
Prabhava –Rasavirya vipakanam samnayam yatra lakshyate. Visheshah karmanam chaiv prabhavastasaya sa smritah.[6] It is called as Achintaya i.e., which is unexplainable on the logic of Bhutas.
D1: Amla rasa dravya, Madhura vipaka – pm constitution how to understand
D2 : ONLY PHARMACOLOGICALLY ACTIVE PRINCIPLE DIRECTLY PERCIEVABLE???
Throughout charaka Samhita, many references of sambhasha parishad. -7
Rasa sankhya vivechana is the 4th refrence in order
Chaitraratha vana
Hiranyaksha – from yester parts of Europe
Bahlika bhishak – yester Persia - Kankayana
P – Prithvi
J- Jala
T – Teja D3 – Nagarjuna’s version
V – Vayu
A - Akasha
Utkarsha happens by the process of digestion
Asthta lavana
दव्यरसगुणवीर्यविपाकनिमित्ते च क्षयवृद्धि दोषाणाम् साम्यं च | (सु. सू)
CD36 was targeted as a possible lipid taste receptor because it binds to fat molecules (more specifically, long-chain fatty acids),[81] and it has been localized to taste bud cells (specifically, the circumvallate and foliate papillae)
Taste Buds Myth
It is a myth that taste buds for sweet, salty, bitter, and sour things exist on different parts of the tongue. Current research has found that no regional taste differences exist on the tongue. In fact, scientists now understand that all taste buds can detect sweet, salty, sour, and bitter tastes no matter their location.
Sarvendriya utpatti by 3rd month according to Charaka