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MEDIAN NERVE INJURY
Dr CHINMOY MAZUMDER
INDOOR MEDICAL OFFICER
DEPARTMENT OF ORTHOPAEDICS
EMCH
1/7/2019
Outline
• Anatomy
 Course
 Motor distribution
 Sensory distribution
• Common sites affected
• Level of median nerve injury
• Clinical feature with various test performed
•Treatment
• Various syndromes related to median nerve
• Summary
1/7/2019
Anatomy of Median Nerve
• Mixed nerve (contain
motor & sensory
fibers).
• Runs in the median
plane of the forearm ,
so its called median
nerve
 Also called labourer’s
nerve.
Anatomy of a peripheral nerve
1/7/2019
Anatomy of Median Nerve
The median nerve
has contributions
from essentially the
entire brachial
plexus (C5-T1), and
is formed by
portions of the
lateral and medial
cord. 1/7/2019
Anatomy of Median Nerve
After originating from
the brachial plexus in
the axilla, the median
nerve descends down
the arm, initially lateral
to the brachial artery.
Halfway down the
arm, the nerve crosses
over the brachial
artery, and becomes
situated medially.
1/7/2019
Anatomy of Median Nerve
The median nerve does not
provide motor or sensory
innervation until it reaches the
elbow.
The median nerve courses down
the arm within the lateral
intermuscular septum, deep to the
short head of the biceps and
lateral to the brachial artery.
At the midbrachium, it crosses to
the medial side of the brachial
artery and descends to the
antecubital fossa.
1/7/2019
Anatomy of Median Nerve
In the antecubital fossa, the
median nerve lies deep to the
bicipital aponeurosis, medial to the
antecubital vein, and medial to the
brachial artery,
Although the median nerve is
anterior to the trochlea and
superficial to the brachialis, it
occasionally can be found medial to
the trochlea, such that it lies
anterior to the medial epicondyle.
This is of clinical importance in
elbow dislocations. 1/7/2019
Anatomy of Median Nerve
 At the level of the junction
of the two heads of the
pronator teres, the median
nerve gives off the anterior
interosseous nerve
 The anterior interosseous
nerve quickly dives deep to
the flexor and pronator
mass and travels with the
anterior interosseous artery
(a branch of the ulnar artery)
to travel on the volar surface
of the interosseous
membrane
1/7/2019
Anatomy of Median Nerve
 Distal to the elbow, the
median nerve courses down
the forearm deep to the flexor
digitorum superficialis and
superficial to the flexor
digitorum profundus.
 In the distal 1⁄3 of the
forearm, the median nerve
emerges from beneath the
flexor digitorum superficialis
to lie medial to the flexor
carpi radialis and lateral to the
palmaris longus, before
entering the carpal tunnel.
1/7/2019
Anatomy of Median Nerve
 The median nerve gives a palmar
cutaneous branch that provides
sensation to thenar skin of the
palm, and is most commonly
branches 4 to 5 cm proximal to the
wrist, lying on the ulnar side of the
flexor carpi radialis
 Within the carpal tunnel, the
median nerve divides into three
terminal branches.
 The lateral branches : thumb and
radial side of the index finger
 Terminal branches of the medial
division:
middle finger and radial aspect of the
ring finger. 1/7/2019
Anatomy of Median Nerve
 The lateral-most division
gives off the terminal motor
innervation of the median
nerve, the recurrent motor
branch, that innervates the
abductor pollicis brevis,
flexor pollicis brevis,
opponens pollicis, and the
lateral two lumbricals
before to dividing into its
terminal sensory branches.
1/7/2019
Anatomy of Median Nerve
 •Motor
superficial volar forearm group
• Pronator teres
• Flexor carpi radialis
• Palmaris longus intermediate
group
• Flexor digitorum superficialis
Deep group
• Flexor digitorum profundus
(lateral)
• Flexor pollicis longus
• Pronator quadratus
• Hand
• 1st and 2nd lumbricals
• Opponens pollicis
• Abductor pollicis brevis
• Flexor pollicis brevis 1/7/2019
Sensory innervations
The median nerve is
responsible for the
cutaneous innervation
of part of the hand.This
is achieved via two
branches:
 Palmar cutaneous
branch
 Palmar digital
cutaneous branch
1/7/2019
Anatomy of Median Nerve
1/7/2019
Anatomy of Median Nerve
1/7/2019
Injury to median nerve
 Trauma
 Leprosy
 Poliomyelitis
 Carpel tunnel syndrome
 Pronator syndrome
 Anterior interossieous syndrome
1/7/2019
HIGH MEDIAN NERVE LESION
 AXILLA
Crutch compression
Anterior shoulder dislocation
 UPPERARM
Stabs wound
Ligament of struthers : It is seen 5 cm
proximal to the medial epicondyle and is a
fibrous band that interconnects a bony
spur on the distal humerus to the medial
epicondyle
 ELBOW
Fracture humerus supracondylar in
children
Fracture medial epicondyle
Elbow dislocation
1/7/2019
HIGH MEDIAN NERVE LESION
SIGNS
 Wasting of muscles of forearm
 Wasting of thenar eminence
 Weakness of thumb abduction and opposition
Loss of abductor pollicis brevis + flexor pollicis brevis
 The hand is held with ulnar fingers flexed and index
finger straight (pointing sign) Loss of FDP, FDS, FPL
 Lost sensation at radial three and half digits
 Weak Ok sign
 Ape hand deformity
1/7/2019
LOW MEDIAN NERVE LESION
 INJURYTO DISTALTHIRD OFTHE
FOREARM
I. Cuts in front of the wrist
II. Carpal dislocation
1/7/2019
Low Median Nerve Injuries
 Injury in the distal third of the forearm
 Sparing of the forearm muscles
 Muscles of the hand paralysed
 Anaesthesia over the median nerve
distribution in the hand
 Thenar eminence is wasted and thumb
abduction and opposition are weak
 Sensation lost over the radial three and half
digits and trophic changes may seen
1/7/2019
High Lesion vs Low Lesion
1/7/2019
Clinical feature with
various test performed
1/7/2019
Hand of Benediction
 Lesion Location: Proximal (near the elbow)
 Deficiency:When the patient tries to make a fist,
they are unable to flex the index and middle fingers
due to loss of lateral lumbrical action, leading to the
hand of benediction.The fingers are extended due to
unopposed radial nerve action on the finger
extensors.
1/7/2019
Ape Hand Deformity
 (1) hyper-extended thumb .
 (2) adduction .
 (3) flat thenar eminence .
 This lesion is related to ape
hand due to the fact that loss
of opponens pollicis means
one has an unopposable
thumb (like an ape). It seems
some also believe the term
ape hand refers to the thenar
atrophy. 1/7/2019
Wasting of thenar eminence
1/7/2019
Pronator teres (C6, C7) assessment
The patient’s forearm is extended and fully
pronated.The patient is then instructed to resist
supination of the forearm by the examiner.
1/7/2019
Flexor carpi radialis (C6, C7) assessment
The patient flexes the wrist a long the trajectory of
the forearm.
1/7/2019
FDS (C8, T1) assessment
 To test proximal interphalangeal joint flexion, the
supinated forearm and hand are placed straight.
Each finger is tested separately. Placing the fingers
between the single finger to be tested and the
remaining fingers that are immobilized isolates
this movement.This maneuver places the finger to
be tested in mild flexion at the metacarpal–
phalangeal (knuckle) joint, and stabilizes the
remaining fingers in extension, a position that
allows isolation of the flexor digitorum
superficialis.
1/7/2019
FDS (C8, T1) assessment
1/7/2019
FDP (C8, T1) assessment
 To assess the median
innervation of the flexor
digitorum profundus one
should concentrate on the
index finger.To do so, holding
the metacarpal-phalangeal
and proximal interphalangeal
joints immobile, and have the
patient flex the distal phalanx
against resistance.
1/7/2019
Ochsner’s clasping test
flexor digitorum superficialis and
profundus(lateral half)
1/7/2019
FPL (C8, T1) assessment
: Immobilize the thumb,
except the
interphalangeal joint,
and then ask the patient
to flex the distal phalanx
against resistance.
1/7/2019
Okay” or “circle” sign
 with anterior interosseous nerve
weakness.
A quick way to assess the flexor
digitorum profundus and flexor
pollicis longus innervation from
the anterior interosseous nerve is
to ask the patient to make an okay
sign by touching the tips of the
thumb and index finger together.
With weakness in these muscles, the
distal phalanges cannot flex, and
instead of the fingertips touching,
the volar surfaces of each distal
phalanx make contact 1/7/2019
Pronator quadratus (C7, C8) assessment
Have the patient resist
supination of a fully
flexed and pronated
forearm.With full
forearm flexion,
pronation by the usually
dominant pronator teres
is minimized
1/7/2019
Abductor pollicis brevis (C8, T1) assessment
 :Resist movement of
the thumb away from
the plane of the palm
(palmar abduction),
while stabilizing the
metacarpals of the
remaining fingers.
1/7/2019
Flexor pollicis brevis (C8, T1)assessment
 The patient flexes the thumb at
the metacarpalphalangeal joint
against resistance placed over
both the proximal and distal
phalanges.
Make certain the distal
interphalangeal joint does not
flex because in allowing this,
substitution by the flexor pollicis
longus occurs.
Use other hand to immobilize the
first metacarpal to reduce
substitution by the opponens
pollicis. 1/7/2019
Opponens pollicis (C8, T1)assessment
Have the patient forcibly
maintain contact between the
volar pads of the distal thumb
and fifth digit, while try to pull
the distal first metacarpal away
from the fifth digit.Although
thumb opposition is only
innervated by the median
nerve, a combination of thumb
adduction (adductor pollicis,
ulnar nerve) and thumb flexion
(flexor pollicis brevis, deep
head, ulnar nerve) may mimic
thumb opposition even when
there is complete median
nerve palsy present
1/7/2019
Lumbrical of second digit assessment
Stabilize the patient’s
index finger in a hyper-
extended position at the
metacarpal-phalangeal
joint and then provide
resistance as the patient
extends the finger at the
proximal interphalangeal
joint.
1/7/2019
Screening for median nerve
1/7/2019
Sensory system examination
 Modality test – pain , touch , temperature ,
pressure and vibration
 Functional tests –two point discrimination
,seddons coin test ,ridge sensitometer
1/7/2019
Objective test
(a)Tinel’s sign
(b)Skin resistance test
(c)wrinkle test
(d) sweat test (iodine starch test)
1/7/2019
Tinel’s sign
Tested by gentle percussion
along course of nerve from
distal to proximal direction.
–Tingling sensation felt by
patient in distribution of
nerve.
–Tingling should persist for
several seconds
• Importance ofTinel’s sign
–Whether Nerve
interrupted
–Whether in Process of
regeneration
1/7/2019
Electrophysiological study
Electromyography
To determine completeness of a nerve injury
Technique:
I. Very small needle is inserted into various muscle
II. Then, the signal is magnified by high gain amplifier
III. Finally, the reading are monitored via oscilloscope and
recorded on the magnetic tape or paper recording
IV. Should performed 3-7 days after peripheral nerve
Injury
V. It may show low amplitude evoked compound muscle
potential (CMAP)
1/7/2019
Nerve conduction test
– First calculate threshold by
stimulating on sound side
 Measure Median motor and
sensory latencies and conduction
velocities across the wrist
 Sensory latency of greater than
3.5 millisecond or a motor latency
of greater than 4.5 millisecond is
considered an abnormal finding
 Distal compound muscle action
potential (CMAP) and sensory
nerve action potential (SNAP)
amplitudes may be decreased 1/7/2019
CLASSIFICATION OF NERVE
INJURIES
SEDDON’S CLASSIFICATION
 Neuropraxia – temporary paralysis of a nerve
caused by lack of blood flow or by pressure on
the affected nerve with no loss of structural
continuity.
 Axonotmesis – neural tube is intact but axons
are disrupted. Nerves are likely to recover.
 Neurotmesis – neural tube is severed. Injuries
are likely to be permanent without repair.
1/7/2019
SUNDERLAND’S CLASSIFICATION
1/7/2019
Principles of Surgical
Management
1. Direct Injury:
Nerve repair-
2. Long standing cases:
Tendon transfers
Nerve transfers
Nerve graft
3. Compression neuropathies:
Decompression
1/7/2019
General indications of surgery
 In sharp injury exploration for diagnostic as
well as therapeutic purpose .Neurorrhaphy
can be done at time of exploration or delayed
 In avulsion or blast injury –to identify and
suture of nerve ends for delayed repair
 When a nerve deficit follows blunt or closed
trauma and no clinical or electrical evedence
of regeneration has occurred after an
appropriate time
1/7/2019
Time of surgery
 Primary repair within 6-8 hours gives best
results
 Delayed primary repair – between 7- 18 days
 Secondary repair - 3 to 6 weeks later
preferable in crushed ,avulsed , contaminated
wounds where patients life is seriously
endangerd
1/7/2019
Surgical techniques
Coaptation
 Approximating the cut ends of nerve in such a
way that motor fasiculi meets another motor
fasiculi and sensory to sensory
 Conventionally done by 8-0 to 10-0 nylon
suture
 Sutureless methods includes fibrin clots,
adhesive tapes ,collagen tubulization
1/7/2019
Neurorrhaphy
Neurorrhaphy is end to end suturing of nerve
Types
 Partial Neurorrhaphy
 Epineural Neurorrhaphy
 Perineural (fascicular) Neurorrhaphy
 Epiperineural Neurorrhaphy
 Interfascicular nerve grafting
1/7/2019
Epineural neurorrhaphy
1/7/2019
Perineural neurorrhaphy
1/7/2019
Epiperineural neurorrhaphy
1/7/2019
Inter fascicular nerve
grafting
1/7/2019
Nerve grafting
A gap between cut ends more than 2.5-4 cm is
indication of nerve graft
Types of grafts
 Trunk graft
 Cable graft
 Pedicle nerve graft
 Inter fascicular nerve graft
 Pre vascularised nerve graft
A cutaneous nerve for nerve grafting should be selected with great
care .Nerves used for graft
 Most commonly sural nerve
 Latral antebrachial cutaneous nerve
1/7/2019
Critical Limit of Delay of Suture
 Motor recovery in intrinsic muscles of the
hand does not occur if suture is delayed 9
months in high lesions or 12 months in low
ones.
 Useful sensory recovery only rarely occurs
after 9 months in high lesions or 12 months in
low ones but it may occur when suture has
been delayed as long as 2 years.
1/7/2019
Prognosis
Prognosis of nerve regeneration depends upon
several factors
Type of lesion:
Neuropraxia always recovers fully,axonotmesis
may or may not,neurotmesis will not unless the
nerve is repaired
Level of lesion
The higher the lesion the worse the prognosis
Type of nerve
Purely motor or purely sensory nerves recover
better than mixed nerves,because there is less
likelihood of axonal confusion.
1/7/2019
Prognosis
Condition of nerve ends
It is generally agreed that the nerve ends should be
prepared in such a way that satisfactory fascicular pattern
is apparent I both proximal and distal stumps.no scar
,foreign material or necrotic tissue should be allowed to
remain about the ends to interfere with axonal
regeneration.
Size of gap
Above the critical resection length ,suture is not
successful
Age
Children do better than adaults . Old people do poorly
1/7/2019
Prognosis
Delay in suture
The best results are obtained with early nerve repair,
after few months , recovery following suture becomes
progressively less likely.
Associated lesions
Damage to vessels , tendons and other structures
makes it more difficult to obtain recovery of a useful
limb even if the nerve itself recovers.
Surgical techniques
Skill , experience and suitable facilities are needed to
treat nerve injuries
1/7/2019
Results of suture of Median nerve
 Under favorable circumstances about 50% of the
patients with median nerve suture recover
sensitivity to pain touch and some degree of
stereognosis .
 Under the same circumstances about 90% of
these patients recover a useful degree of maotor
function in the long flexors of the forearm
 A much smaller number , perhaps 33% obtain
useful recovery in the thenar muscles as well
when the lesion is in the upper arm
 In more distal lesions about 67% will attain some
useful motor recovery. 1/7/2019
Reconstructive procedure
Tendon transfer
 Motor recovery may not occur if the axons
,regenerating at about 1 mm per day / 2-3 cm per
month , don not reach the muscle within 18-24
months of injury.This is most likely when there is a
proximal injury I a nerve supplying distal muscles.
 In such circumstances , tendon transfers should be
considered
 When neighboring tendons are intact and if all
criteria for tendon transfer met ,then tendon
transfer is treatment of choice 1/7/2019
Tendon transfer
Tendon transfer should be delayed for 6 months
a) Low Median Nerve:
- Re-routing of ring/ middle finger superficial
flexor around FCU to APB to aid thumb
opposition
b) High Median Nerve:
- Suturing of profundus tendons to ring and
small finger tendons for restoration of IP joint
movements
1/7/2019
Criteria for tendon transfer
 Muscle power grade 5 (preferably),if not atleast
grade 4
 Should have its own nerve and blood supply
 Synergistic group are chosen because of easier
rehabilitation
 Age should be more than 5 years
 Disease should not progress and infection to be
controlled
 Prior to transfer joint stiffness,contracture and
malunion are corrected
 Tendon transferred should not be at an acute angle
1/7/2019
Restoring thumb opposition:
 Thumb opposition is a complex movement that
involves palmar abduction, pronation, and flexion of
the thumb metacarpal and proximal phalanx.
 The ideal insertion for an opposition transfer is the
APB insertion. Insertion at this point most reliably
causes the combination of movements that result in
thumb opposition.
 The angle of pull should be from the location of the
pisiform, because this approximates the normal
direction of pull of the APB.
1/7/2019
The superficialis opponensplasty
 Described by Royle in 1938,
involves dividing the ring finger
FDS distally in the finger,
retrieving the FDS proximal to
the carpal tunnel, re-directing
the tendon distally through the
FPL sheath, and inserting it into
the thumb.
 The main disadvantage of the
superficialis opponensplasty is
that it can only be used in cases
of low median nerve palsy,
because the FDS is paralyzed in
high median nerve palsy 1/7/2019
The EIP(extensor indicis
propius)opponensplasty
 In cases of both low and high median nerve injury, and is
the most commonly employed opposition transfer in
high median nerve palsy
 Although the EIP is a weak motor, it is sufficiently
strong to move the thumb into opposition.
 The EIP is tunneled around the ulnar aspect of the wrist,
routed across the palm from the level of the pisiform,
and inserted on the APB.
 It is important to close the extensor hood of the index
MCPJ after EIP harvest to prevent postoperative
extension lag at the index MCPJ.
 Functional loss with the EIP transfer is minimal, and
retraining the EIP to perform thumb opposition is not
difficult. 1/7/2019
EIP Opponensplasty
1/7/2019
The Huber transfer
Employs the ulnar nerve-innervated abductor
digiti minimi (ADM) to restore opposition.
 This transfer is usually used in cases of
congenital absence of the thenar muscles, and in
cases where the FDS and EIP are not available.
 The ADM is released from its insertion, turned
over 180 degrees, and inserted on the APB
insertion.
 Strength and excursion are well matched to the
deficit, and the transfer is synergistic
1/7/2019
HUBER PROCEDURE
1/7/2019
Tendon transfers
Other procedures
 In cases of high median nerve injury, thumb IPJ
flexion and index finger DIPJ flexion can be restored
with transfer of the BR, the ECRL, or ECU.
 The most common transfers are BR to FPL and
ECRL to index FDP. However, it should be
remembered that reinnervation of the FPL and FDP
is common after a high median nerve injury has
been repaired.
 - ECU re-routing and attachment to dorsal
radius/Transfer of biceps insertion from medial to
lateral radius for weak forearm pronation
1/7/2019
Camitz procedure
 PL transfer effectively
restores palmar abduction,
the pronation and flexion
components of opposition
are not re-established.
 The primary indication for
performing a Camitz
transfer is to augment
palmar abduction in
patients who have motor
loss from severe carpal
tunnel syndrome.
1/7/2019
Rehabilitation
First 4 weeks:
 Splint that should take tension off the tendon
transfer(s) performed. For example, if a transfer was
performed to improve clawing, the splint should keep
the MCPJ’s flexed and the IPJ’s extended.
 Maintain mobility in the non-immobilized joints of the
upper extremity. After 4 weeks:
Mobilization should start with gentle active and
assisted range of motion exercises. It is important to
mobilize one joint at a time to prevent placing too
much tension on the transfer. For example, if an ECRB
transfer to treat clawing was performed, the therapist
should mobilize the MCPJ’s while keeping the wrist and
IPJ’s immobile. 1/7/2019
Rehabilitation
 6 weeks: exercises that activate the muscles
used in the tendon transfer, and should begin
muscle retraining. Electrical stimulation and
biofeedback may be used to assist with
retraining.
 8 weeks: At eight weeks postoperatively,
strengthening exercises should be initiated,
and the splint can be weaned off over the
next four weeks.
 Full activity is resumed at twelve weeks.
1/7/2019
Nerve transfers
 To achieve opposition,sensations, flexion &
Pronation
AIN to Median recurrent transfer for lower median
nerve palsy
Thumb
opposition
1/7/2019
Nerve tranfers
 Median recurrent neurotisation for high
median nerve palsy
 Ulner-median nerve transfer (3rd lumbricle
branch to recurrent median nerve branch
transfer)
 Radial-median nerve transfer (PIN branches
to Recurrent median nerve branch transfer)
1/7/2019
Sensory restoration for median nerve
 Essential for fine motor tasks,motor recovery
is dependant on the quality of sensations, some
believe it a prerequisite for motor restoration
1/7/2019
Nerve transfers
 Nerve transfers for restoration of flexion in
high median nerve palsy ECRB branch of
the radial nerve to the AIN transfer without
grafts
1/7/2019
Nerve transfers
 Nerve transfers for restoration of flexion in
high median nerve palsy Isolated AIN
injuries, nerves of FDS, PL & FCR can be
utilized
1/7/2019
Median nerve compression
• Carpel tunnel syndrome
• Pronator syndrome
• Anterior interosseous syndrome
1/7/2019
Carpel tunnel syndrome
Definition
It’s a Clinical Diagnose Of
peripheral neuropathy,
results from compression of
the median nerve at the
wrist
CTS First described by Sir James Paget 1854
• First CTR performed by Sir James Learmonth 1933
• Popularised by Phalen in the 1950s with a series of
articles
• Introduction of endoscopic release 1985-1987
1/7/2019
Anatomy - Carpal Tunnel
 The bony borders are:
radially, the tubercle of
the scaphoid and the
tubercle of the
trapezium; ulnarly the
triquetrum, pisiform and
hook of the hamate.The
lunate lies in the floor of
the tunnel.
• Nine tendons run through
the tunnel: the 4 FDS,
the 4 FDP, and FPL. FCR
runs in a separate fascial
compartment on the
radial side of the tunnel.; 1/7/2019
Causes and contributing factors
in Carpal Tunnel Syndrome
 Idiopathic : Most common
 Aberrant anatomy
-Anomalous flexor tendons
-Congenitally small carpal canal
-Ganglionic cysts
-Lipoma
-Proximal lumbrical muscle insertions
-Thrombosed artery
 Infections
 Lyme disease
 Mycobacterial infection
 Septic arthritis
• Inflammatory conditions
-Connective tissue disease
-gout or pseudogout
-Nonspecific tenosynovitis
•Metabolic Conditions
-Acromegaly
-Amyloidosis
-Diabetes Mellitus
-Hypothyroidism or Hyperthyroidism
•Increased canal volume
-Congestive heart failure
-Oedema
-Obesity
-Pregnancy
•Repetitive wrist movements:Typists &
Computer users
1/7/2019
Symptoms
 Hand and wrist Pain
 Paraesthesia
 Hypoaesthsia
 Sparing of Palmar cutaneous branch
supply
 Patient wakes at night with burning
or aching pain and shakes the hand to
obtain relief and restore sensation
 Aggravated by elevation of hand
 Difficulty in holding on to a glass or
cup securely
 Thenar atrophy and weakness of
thumb opposition and abduction may
develop late 1/7/2019
Carpal Tunnel Syndrome
MNEMONIC
PRAGMATIC
 P-PREGNANCY
 R-RHEUMATOID ARTHRITIS
 A-ATHRITIS DEGENERATIVE
 G-GROWTH HORMONE EXCESS
i.e. ACROMEGALY
 M-METABOLIC i.e. GOUT
 A-ALCOHOLISM
T-TUMORS
 I-IDIOPATHIC
 C-CONNECTIVETISSUE
DISORDER i.e. AMYLOIDOSIS
1/7/2019
Pathophysiology of CTS
Night numbness is caused by a number of
factors:
• Horizontal position results in a redistribution
of fluid to the upper limbs
• Drainage by the action of the muscle pump is
diminished
•There is a tendency towards wrist flexion at
night
•The blood pressure drops during late night and
early morning, resulting in decreased perfusion
pressure
1/7/2019
Diagnosis
 History
 Clinical examination:
-Thenar wasting
- Phalen’s sign
-Tinel’s sign
- Carpal compression test
 Electro Diagnostic Studies:
-Very reliable for evaluation
- Atypical cases may be present
1/7/2019
Signs of CTS
 Thenar muscle wasting due to continued pressure
1/7/2019
Phalen’s test
 Phalen’s test
Patients is asked to
actively place the
wrist in complete
but forced flexion
+ve if tingling and
numbness is
produced in 60 sec.
Sensitive and
specific in 80%
1/7/2019
Median Compression test/ Durkan’s
test
 Median nerve
compression test
Direct pressure is
exerted over both wrist
1st phase –time taken
for symptoms appear(15-
20sec)
2nd phase-time taken
for symptoms to
disappear after release of
pressure
1/7/2019
 Tourniquet test
BP cuff tied proximal to elbow and inflated
higher than patient’s Systolic BP.
+ve if numbness and paraesthesia
1/7/2019
Treatment
 CONSERVATIVETREATMENTS
-General measures
-Oral medications
-Local injection
-Wrist splints
 Surgical decompression:
Division of the transverse carpal ligament
- Open
- Endoscopic
1/7/2019
ORAL MEDICATIONS
• Diuretics
• Nonsteroidal anti-inflammatory drugs
(NSAIDs)
•Thiamime (Vitamin B1)pyridoxine (vitamin
B6)
Cyanocobalamin(Vitamin B12)
• Orally administered corticosteroids
▫ Prednisolone
▫ 20 mg per day for two weeks
▫ followed by 10 mg per day for two weeks
1/7/2019
Steroid Injection
•Transient relief occurs in 80% of patients after
steroid injection
• But only 22% of patients with steroid
injections are pain free at 12 months
 (These patients were also splinted).
– It is most useful early in the disease, when
there has been less than 1yr of symptoms
– there is no weakness or thenar atrophy
•Technique of injection:
– a 22-gauge needle is introduced between FCR
and PL
– angled dorsally and distally at 45 degrees
– It is advanced until it reaches the floor of the
tunnel, and then withdrawn 5mm
– A water soluble preparation is used
• e.g. dexamethasone acetate plus lignocaine
• if any immediate paraesthesias occur the
injection is stopped. 1/7/2019
Orthoses
 The following orthoses help manage the carpal
tunnel syndrome pain:
–Wrist hand orthosis
–Thumb spica splint
– Cock-up wrist splint
1/7/2019
Orthotics goals
 Decrease pain and swelling
 Prevent deformity progression
 Prevent Movement
 By restrict flexion movement of wrist
 Main objective is to position wrist in neutral
but preferably slight extension to get
pressure off of median nerve
1/7/2019
SURGERY
 Should be considered in patients with symptoms
that do not respond to conservative measures and in
patients with severe nerve entrapment as evidenced
by nerve conduction studies,thenar atrophy, or
motor weakness.
• It is important to note that surgery may be effective
even if a patient has normal nerve conduction
studies
Methods of Surgery
 Open CarpalTunnel Release
– Open technique
– Limited incision technique
 Endoscopic CarpalTunnel Release 1/7/2019
Open Carpal Tunnel Release
1/7/2019
Endoscopic Carpal Tunnel Release
1/7/2019
Complications Of Surgery
 Early
–Transection of the
median nerve or the
superficial arch
– Haematoma
– Pain, swelling and
stiffness
– Recurrent Branch injury
– Infection
•Late
– RSD
– Hypertrophic scar
– Median nerve neuritis
– Palmar fasciitis
– Fibrosis of carpal tunnel
– Recurrence
•Revision carpal tunnel
release
– Only 25% of patients have
complete relief of symptoms.
25% have no relief.The rest
have partial relief.1/7/2019
Postoperative course and
results for Open CTR
 Grip strength returns to normal in 3 months.
 Surgery is most successful when done early;
Patients with intermittent numbness do better than
patients with constant numbness.
 Overall excellent results in 80% (Mayo clinic). 5%
have worsened function.
 MRI shows a 20-30% increase in the carpal tunnel
volume after surgery. MRI also shows that Guyon’s
canal enlarges after carpal tunnel release.
 Measurement of pressures within the carpal tunnel
before and after release demonstrate marked
decreases in resting pressures after release of the
ligament.
1/7/2019
Differential Diagnoses of CTS
 Tendonitis
 Tenosynovitis
 Diabetic neuropathy
 Kienbock's disease
 Compression of the Median nerve at the
elbow
1/7/2019
Pronator Syndrome
- Proximal Forearm Compression
- Because Of :-
 ligament of Struthers,
 lacertus fibrosus,
 pronator teres muscle
1/7/2019
Symptoms & signs
 Symptoms are similar to those of carpal tunnel syndrome
 Sensory disturbances
-Thumb & Index > Middle finger
 Night pain is unusual and forearm pain is more common
 Hand numbness on gripping
 Phalen’s test negative
 Symptoms provoked by resisted elbow flexion with
forearm supinated ( tightening of bicipital aponeurosis )
 By resisted forearm pronation with the elbow extended
( pronator tension )
1/7/2019
Same Symptoms As C.T.S But
Could Be
Differentiated By
 include the distribution of the palmar
cutaneous nerve
 TheTinel sign is positive at the forearm level
 The Phalen maneuver does not provoke
symptoms
 Patients may experience pain with resistance
to contraction of the pronator teres or flexor
digitorum superficialis
1/7/2019
Management
 No relief with steroids
 Surgical decompression
1/7/2019
Anterior Interosseous
Syndrome
 Damage to the Anterior Interosseous Nerve
 Causes
•Tentinous origin of flexor digitorum
•Pronater teres
•Tendons from flexor digitorum to flexor policis
longus
•Accessory head of flexor policis longus (gantzer
muscle)
•Aberrant radial artery
•Thrombosis of ulnar colleteral artery
•VIC
1/7/2019
Anterior Interosseous
Syndrome
 Pain in the forearm
 Weakness of the gripping movement of the
thumb and index finger( unable to make ok sign
)
 Clinical Findings
-inability to flex either the thumb
interphalangeal joint or the index-finger distal
interphalangeal joint
-In contrast to those with pronator syndrome,
these patients do not complain of numbness or
pain 1/7/2019
Anterior Interosseous Syndrome
Management
Corticosteroids
Surgery:
- Resection/detachment of deep head of PT
1/7/2019
THANK YOU ALL
1/7/2019

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Median nerve injury

  • 1. MEDIAN NERVE INJURY Dr CHINMOY MAZUMDER INDOOR MEDICAL OFFICER DEPARTMENT OF ORTHOPAEDICS EMCH 1/7/2019
  • 2. Outline • Anatomy  Course  Motor distribution  Sensory distribution • Common sites affected • Level of median nerve injury • Clinical feature with various test performed •Treatment • Various syndromes related to median nerve • Summary 1/7/2019
  • 3. Anatomy of Median Nerve • Mixed nerve (contain motor & sensory fibers). • Runs in the median plane of the forearm , so its called median nerve  Also called labourer’s nerve. Anatomy of a peripheral nerve 1/7/2019
  • 4. Anatomy of Median Nerve The median nerve has contributions from essentially the entire brachial plexus (C5-T1), and is formed by portions of the lateral and medial cord. 1/7/2019
  • 5. Anatomy of Median Nerve After originating from the brachial plexus in the axilla, the median nerve descends down the arm, initially lateral to the brachial artery. Halfway down the arm, the nerve crosses over the brachial artery, and becomes situated medially. 1/7/2019
  • 6. Anatomy of Median Nerve The median nerve does not provide motor or sensory innervation until it reaches the elbow. The median nerve courses down the arm within the lateral intermuscular septum, deep to the short head of the biceps and lateral to the brachial artery. At the midbrachium, it crosses to the medial side of the brachial artery and descends to the antecubital fossa. 1/7/2019
  • 7. Anatomy of Median Nerve In the antecubital fossa, the median nerve lies deep to the bicipital aponeurosis, medial to the antecubital vein, and medial to the brachial artery, Although the median nerve is anterior to the trochlea and superficial to the brachialis, it occasionally can be found medial to the trochlea, such that it lies anterior to the medial epicondyle. This is of clinical importance in elbow dislocations. 1/7/2019
  • 8. Anatomy of Median Nerve  At the level of the junction of the two heads of the pronator teres, the median nerve gives off the anterior interosseous nerve  The anterior interosseous nerve quickly dives deep to the flexor and pronator mass and travels with the anterior interosseous artery (a branch of the ulnar artery) to travel on the volar surface of the interosseous membrane 1/7/2019
  • 9. Anatomy of Median Nerve  Distal to the elbow, the median nerve courses down the forearm deep to the flexor digitorum superficialis and superficial to the flexor digitorum profundus.  In the distal 1⁄3 of the forearm, the median nerve emerges from beneath the flexor digitorum superficialis to lie medial to the flexor carpi radialis and lateral to the palmaris longus, before entering the carpal tunnel. 1/7/2019
  • 10. Anatomy of Median Nerve  The median nerve gives a palmar cutaneous branch that provides sensation to thenar skin of the palm, and is most commonly branches 4 to 5 cm proximal to the wrist, lying on the ulnar side of the flexor carpi radialis  Within the carpal tunnel, the median nerve divides into three terminal branches.  The lateral branches : thumb and radial side of the index finger  Terminal branches of the medial division: middle finger and radial aspect of the ring finger. 1/7/2019
  • 11. Anatomy of Median Nerve  The lateral-most division gives off the terminal motor innervation of the median nerve, the recurrent motor branch, that innervates the abductor pollicis brevis, flexor pollicis brevis, opponens pollicis, and the lateral two lumbricals before to dividing into its terminal sensory branches. 1/7/2019
  • 12. Anatomy of Median Nerve  •Motor superficial volar forearm group • Pronator teres • Flexor carpi radialis • Palmaris longus intermediate group • Flexor digitorum superficialis Deep group • Flexor digitorum profundus (lateral) • Flexor pollicis longus • Pronator quadratus • Hand • 1st and 2nd lumbricals • Opponens pollicis • Abductor pollicis brevis • Flexor pollicis brevis 1/7/2019
  • 13. Sensory innervations The median nerve is responsible for the cutaneous innervation of part of the hand.This is achieved via two branches:  Palmar cutaneous branch  Palmar digital cutaneous branch 1/7/2019
  • 14. Anatomy of Median Nerve 1/7/2019
  • 15. Anatomy of Median Nerve 1/7/2019
  • 16. Injury to median nerve  Trauma  Leprosy  Poliomyelitis  Carpel tunnel syndrome  Pronator syndrome  Anterior interossieous syndrome 1/7/2019
  • 17. HIGH MEDIAN NERVE LESION  AXILLA Crutch compression Anterior shoulder dislocation  UPPERARM Stabs wound Ligament of struthers : It is seen 5 cm proximal to the medial epicondyle and is a fibrous band that interconnects a bony spur on the distal humerus to the medial epicondyle  ELBOW Fracture humerus supracondylar in children Fracture medial epicondyle Elbow dislocation 1/7/2019
  • 18. HIGH MEDIAN NERVE LESION SIGNS  Wasting of muscles of forearm  Wasting of thenar eminence  Weakness of thumb abduction and opposition Loss of abductor pollicis brevis + flexor pollicis brevis  The hand is held with ulnar fingers flexed and index finger straight (pointing sign) Loss of FDP, FDS, FPL  Lost sensation at radial three and half digits  Weak Ok sign  Ape hand deformity 1/7/2019
  • 19. LOW MEDIAN NERVE LESION  INJURYTO DISTALTHIRD OFTHE FOREARM I. Cuts in front of the wrist II. Carpal dislocation 1/7/2019
  • 20. Low Median Nerve Injuries  Injury in the distal third of the forearm  Sparing of the forearm muscles  Muscles of the hand paralysed  Anaesthesia over the median nerve distribution in the hand  Thenar eminence is wasted and thumb abduction and opposition are weak  Sensation lost over the radial three and half digits and trophic changes may seen 1/7/2019
  • 21. High Lesion vs Low Lesion 1/7/2019
  • 22. Clinical feature with various test performed 1/7/2019
  • 23. Hand of Benediction  Lesion Location: Proximal (near the elbow)  Deficiency:When the patient tries to make a fist, they are unable to flex the index and middle fingers due to loss of lateral lumbrical action, leading to the hand of benediction.The fingers are extended due to unopposed radial nerve action on the finger extensors. 1/7/2019
  • 24. Ape Hand Deformity  (1) hyper-extended thumb .  (2) adduction .  (3) flat thenar eminence .  This lesion is related to ape hand due to the fact that loss of opponens pollicis means one has an unopposable thumb (like an ape). It seems some also believe the term ape hand refers to the thenar atrophy. 1/7/2019
  • 25. Wasting of thenar eminence 1/7/2019
  • 26. Pronator teres (C6, C7) assessment The patient’s forearm is extended and fully pronated.The patient is then instructed to resist supination of the forearm by the examiner. 1/7/2019
  • 27. Flexor carpi radialis (C6, C7) assessment The patient flexes the wrist a long the trajectory of the forearm. 1/7/2019
  • 28. FDS (C8, T1) assessment  To test proximal interphalangeal joint flexion, the supinated forearm and hand are placed straight. Each finger is tested separately. Placing the fingers between the single finger to be tested and the remaining fingers that are immobilized isolates this movement.This maneuver places the finger to be tested in mild flexion at the metacarpal– phalangeal (knuckle) joint, and stabilizes the remaining fingers in extension, a position that allows isolation of the flexor digitorum superficialis. 1/7/2019
  • 29. FDS (C8, T1) assessment 1/7/2019
  • 30. FDP (C8, T1) assessment  To assess the median innervation of the flexor digitorum profundus one should concentrate on the index finger.To do so, holding the metacarpal-phalangeal and proximal interphalangeal joints immobile, and have the patient flex the distal phalanx against resistance. 1/7/2019
  • 31. Ochsner’s clasping test flexor digitorum superficialis and profundus(lateral half) 1/7/2019
  • 32. FPL (C8, T1) assessment : Immobilize the thumb, except the interphalangeal joint, and then ask the patient to flex the distal phalanx against resistance. 1/7/2019
  • 33. Okay” or “circle” sign  with anterior interosseous nerve weakness. A quick way to assess the flexor digitorum profundus and flexor pollicis longus innervation from the anterior interosseous nerve is to ask the patient to make an okay sign by touching the tips of the thumb and index finger together. With weakness in these muscles, the distal phalanges cannot flex, and instead of the fingertips touching, the volar surfaces of each distal phalanx make contact 1/7/2019
  • 34. Pronator quadratus (C7, C8) assessment Have the patient resist supination of a fully flexed and pronated forearm.With full forearm flexion, pronation by the usually dominant pronator teres is minimized 1/7/2019
  • 35. Abductor pollicis brevis (C8, T1) assessment  :Resist movement of the thumb away from the plane of the palm (palmar abduction), while stabilizing the metacarpals of the remaining fingers. 1/7/2019
  • 36. Flexor pollicis brevis (C8, T1)assessment  The patient flexes the thumb at the metacarpalphalangeal joint against resistance placed over both the proximal and distal phalanges. Make certain the distal interphalangeal joint does not flex because in allowing this, substitution by the flexor pollicis longus occurs. Use other hand to immobilize the first metacarpal to reduce substitution by the opponens pollicis. 1/7/2019
  • 37. Opponens pollicis (C8, T1)assessment Have the patient forcibly maintain contact between the volar pads of the distal thumb and fifth digit, while try to pull the distal first metacarpal away from the fifth digit.Although thumb opposition is only innervated by the median nerve, a combination of thumb adduction (adductor pollicis, ulnar nerve) and thumb flexion (flexor pollicis brevis, deep head, ulnar nerve) may mimic thumb opposition even when there is complete median nerve palsy present 1/7/2019
  • 38. Lumbrical of second digit assessment Stabilize the patient’s index finger in a hyper- extended position at the metacarpal-phalangeal joint and then provide resistance as the patient extends the finger at the proximal interphalangeal joint. 1/7/2019
  • 39. Screening for median nerve 1/7/2019
  • 40. Sensory system examination  Modality test – pain , touch , temperature , pressure and vibration  Functional tests –two point discrimination ,seddons coin test ,ridge sensitometer 1/7/2019
  • 41. Objective test (a)Tinel’s sign (b)Skin resistance test (c)wrinkle test (d) sweat test (iodine starch test) 1/7/2019
  • 42. Tinel’s sign Tested by gentle percussion along course of nerve from distal to proximal direction. –Tingling sensation felt by patient in distribution of nerve. –Tingling should persist for several seconds • Importance ofTinel’s sign –Whether Nerve interrupted –Whether in Process of regeneration 1/7/2019
  • 43. Electrophysiological study Electromyography To determine completeness of a nerve injury Technique: I. Very small needle is inserted into various muscle II. Then, the signal is magnified by high gain amplifier III. Finally, the reading are monitored via oscilloscope and recorded on the magnetic tape or paper recording IV. Should performed 3-7 days after peripheral nerve Injury V. It may show low amplitude evoked compound muscle potential (CMAP) 1/7/2019
  • 44. Nerve conduction test – First calculate threshold by stimulating on sound side  Measure Median motor and sensory latencies and conduction velocities across the wrist  Sensory latency of greater than 3.5 millisecond or a motor latency of greater than 4.5 millisecond is considered an abnormal finding  Distal compound muscle action potential (CMAP) and sensory nerve action potential (SNAP) amplitudes may be decreased 1/7/2019
  • 45. CLASSIFICATION OF NERVE INJURIES SEDDON’S CLASSIFICATION  Neuropraxia – temporary paralysis of a nerve caused by lack of blood flow or by pressure on the affected nerve with no loss of structural continuity.  Axonotmesis – neural tube is intact but axons are disrupted. Nerves are likely to recover.  Neurotmesis – neural tube is severed. Injuries are likely to be permanent without repair. 1/7/2019
  • 47. Principles of Surgical Management 1. Direct Injury: Nerve repair- 2. Long standing cases: Tendon transfers Nerve transfers Nerve graft 3. Compression neuropathies: Decompression 1/7/2019
  • 48. General indications of surgery  In sharp injury exploration for diagnostic as well as therapeutic purpose .Neurorrhaphy can be done at time of exploration or delayed  In avulsion or blast injury –to identify and suture of nerve ends for delayed repair  When a nerve deficit follows blunt or closed trauma and no clinical or electrical evedence of regeneration has occurred after an appropriate time 1/7/2019
  • 49. Time of surgery  Primary repair within 6-8 hours gives best results  Delayed primary repair – between 7- 18 days  Secondary repair - 3 to 6 weeks later preferable in crushed ,avulsed , contaminated wounds where patients life is seriously endangerd 1/7/2019
  • 50. Surgical techniques Coaptation  Approximating the cut ends of nerve in such a way that motor fasiculi meets another motor fasiculi and sensory to sensory  Conventionally done by 8-0 to 10-0 nylon suture  Sutureless methods includes fibrin clots, adhesive tapes ,collagen tubulization 1/7/2019
  • 51. Neurorrhaphy Neurorrhaphy is end to end suturing of nerve Types  Partial Neurorrhaphy  Epineural Neurorrhaphy  Perineural (fascicular) Neurorrhaphy  Epiperineural Neurorrhaphy  Interfascicular nerve grafting 1/7/2019
  • 56. Nerve grafting A gap between cut ends more than 2.5-4 cm is indication of nerve graft Types of grafts  Trunk graft  Cable graft  Pedicle nerve graft  Inter fascicular nerve graft  Pre vascularised nerve graft A cutaneous nerve for nerve grafting should be selected with great care .Nerves used for graft  Most commonly sural nerve  Latral antebrachial cutaneous nerve 1/7/2019
  • 57. Critical Limit of Delay of Suture  Motor recovery in intrinsic muscles of the hand does not occur if suture is delayed 9 months in high lesions or 12 months in low ones.  Useful sensory recovery only rarely occurs after 9 months in high lesions or 12 months in low ones but it may occur when suture has been delayed as long as 2 years. 1/7/2019
  • 58. Prognosis Prognosis of nerve regeneration depends upon several factors Type of lesion: Neuropraxia always recovers fully,axonotmesis may or may not,neurotmesis will not unless the nerve is repaired Level of lesion The higher the lesion the worse the prognosis Type of nerve Purely motor or purely sensory nerves recover better than mixed nerves,because there is less likelihood of axonal confusion. 1/7/2019
  • 59. Prognosis Condition of nerve ends It is generally agreed that the nerve ends should be prepared in such a way that satisfactory fascicular pattern is apparent I both proximal and distal stumps.no scar ,foreign material or necrotic tissue should be allowed to remain about the ends to interfere with axonal regeneration. Size of gap Above the critical resection length ,suture is not successful Age Children do better than adaults . Old people do poorly 1/7/2019
  • 60. Prognosis Delay in suture The best results are obtained with early nerve repair, after few months , recovery following suture becomes progressively less likely. Associated lesions Damage to vessels , tendons and other structures makes it more difficult to obtain recovery of a useful limb even if the nerve itself recovers. Surgical techniques Skill , experience and suitable facilities are needed to treat nerve injuries 1/7/2019
  • 61. Results of suture of Median nerve  Under favorable circumstances about 50% of the patients with median nerve suture recover sensitivity to pain touch and some degree of stereognosis .  Under the same circumstances about 90% of these patients recover a useful degree of maotor function in the long flexors of the forearm  A much smaller number , perhaps 33% obtain useful recovery in the thenar muscles as well when the lesion is in the upper arm  In more distal lesions about 67% will attain some useful motor recovery. 1/7/2019
  • 62. Reconstructive procedure Tendon transfer  Motor recovery may not occur if the axons ,regenerating at about 1 mm per day / 2-3 cm per month , don not reach the muscle within 18-24 months of injury.This is most likely when there is a proximal injury I a nerve supplying distal muscles.  In such circumstances , tendon transfers should be considered  When neighboring tendons are intact and if all criteria for tendon transfer met ,then tendon transfer is treatment of choice 1/7/2019
  • 63. Tendon transfer Tendon transfer should be delayed for 6 months a) Low Median Nerve: - Re-routing of ring/ middle finger superficial flexor around FCU to APB to aid thumb opposition b) High Median Nerve: - Suturing of profundus tendons to ring and small finger tendons for restoration of IP joint movements 1/7/2019
  • 64. Criteria for tendon transfer  Muscle power grade 5 (preferably),if not atleast grade 4  Should have its own nerve and blood supply  Synergistic group are chosen because of easier rehabilitation  Age should be more than 5 years  Disease should not progress and infection to be controlled  Prior to transfer joint stiffness,contracture and malunion are corrected  Tendon transferred should not be at an acute angle 1/7/2019
  • 65. Restoring thumb opposition:  Thumb opposition is a complex movement that involves palmar abduction, pronation, and flexion of the thumb metacarpal and proximal phalanx.  The ideal insertion for an opposition transfer is the APB insertion. Insertion at this point most reliably causes the combination of movements that result in thumb opposition.  The angle of pull should be from the location of the pisiform, because this approximates the normal direction of pull of the APB. 1/7/2019
  • 66. The superficialis opponensplasty  Described by Royle in 1938, involves dividing the ring finger FDS distally in the finger, retrieving the FDS proximal to the carpal tunnel, re-directing the tendon distally through the FPL sheath, and inserting it into the thumb.  The main disadvantage of the superficialis opponensplasty is that it can only be used in cases of low median nerve palsy, because the FDS is paralyzed in high median nerve palsy 1/7/2019
  • 67. The EIP(extensor indicis propius)opponensplasty  In cases of both low and high median nerve injury, and is the most commonly employed opposition transfer in high median nerve palsy  Although the EIP is a weak motor, it is sufficiently strong to move the thumb into opposition.  The EIP is tunneled around the ulnar aspect of the wrist, routed across the palm from the level of the pisiform, and inserted on the APB.  It is important to close the extensor hood of the index MCPJ after EIP harvest to prevent postoperative extension lag at the index MCPJ.  Functional loss with the EIP transfer is minimal, and retraining the EIP to perform thumb opposition is not difficult. 1/7/2019
  • 69. The Huber transfer Employs the ulnar nerve-innervated abductor digiti minimi (ADM) to restore opposition.  This transfer is usually used in cases of congenital absence of the thenar muscles, and in cases where the FDS and EIP are not available.  The ADM is released from its insertion, turned over 180 degrees, and inserted on the APB insertion.  Strength and excursion are well matched to the deficit, and the transfer is synergistic 1/7/2019
  • 71. Tendon transfers Other procedures  In cases of high median nerve injury, thumb IPJ flexion and index finger DIPJ flexion can be restored with transfer of the BR, the ECRL, or ECU.  The most common transfers are BR to FPL and ECRL to index FDP. However, it should be remembered that reinnervation of the FPL and FDP is common after a high median nerve injury has been repaired.  - ECU re-routing and attachment to dorsal radius/Transfer of biceps insertion from medial to lateral radius for weak forearm pronation 1/7/2019
  • 72. Camitz procedure  PL transfer effectively restores palmar abduction, the pronation and flexion components of opposition are not re-established.  The primary indication for performing a Camitz transfer is to augment palmar abduction in patients who have motor loss from severe carpal tunnel syndrome. 1/7/2019
  • 73. Rehabilitation First 4 weeks:  Splint that should take tension off the tendon transfer(s) performed. For example, if a transfer was performed to improve clawing, the splint should keep the MCPJ’s flexed and the IPJ’s extended.  Maintain mobility in the non-immobilized joints of the upper extremity. After 4 weeks: Mobilization should start with gentle active and assisted range of motion exercises. It is important to mobilize one joint at a time to prevent placing too much tension on the transfer. For example, if an ECRB transfer to treat clawing was performed, the therapist should mobilize the MCPJ’s while keeping the wrist and IPJ’s immobile. 1/7/2019
  • 74. Rehabilitation  6 weeks: exercises that activate the muscles used in the tendon transfer, and should begin muscle retraining. Electrical stimulation and biofeedback may be used to assist with retraining.  8 weeks: At eight weeks postoperatively, strengthening exercises should be initiated, and the splint can be weaned off over the next four weeks.  Full activity is resumed at twelve weeks. 1/7/2019
  • 75. Nerve transfers  To achieve opposition,sensations, flexion & Pronation AIN to Median recurrent transfer for lower median nerve palsy Thumb opposition 1/7/2019
  • 76. Nerve tranfers  Median recurrent neurotisation for high median nerve palsy  Ulner-median nerve transfer (3rd lumbricle branch to recurrent median nerve branch transfer)  Radial-median nerve transfer (PIN branches to Recurrent median nerve branch transfer) 1/7/2019
  • 77. Sensory restoration for median nerve  Essential for fine motor tasks,motor recovery is dependant on the quality of sensations, some believe it a prerequisite for motor restoration 1/7/2019
  • 78. Nerve transfers  Nerve transfers for restoration of flexion in high median nerve palsy ECRB branch of the radial nerve to the AIN transfer without grafts 1/7/2019
  • 79. Nerve transfers  Nerve transfers for restoration of flexion in high median nerve palsy Isolated AIN injuries, nerves of FDS, PL & FCR can be utilized 1/7/2019
  • 80. Median nerve compression • Carpel tunnel syndrome • Pronator syndrome • Anterior interosseous syndrome 1/7/2019
  • 81. Carpel tunnel syndrome Definition It’s a Clinical Diagnose Of peripheral neuropathy, results from compression of the median nerve at the wrist CTS First described by Sir James Paget 1854 • First CTR performed by Sir James Learmonth 1933 • Popularised by Phalen in the 1950s with a series of articles • Introduction of endoscopic release 1985-1987 1/7/2019
  • 82. Anatomy - Carpal Tunnel  The bony borders are: radially, the tubercle of the scaphoid and the tubercle of the trapezium; ulnarly the triquetrum, pisiform and hook of the hamate.The lunate lies in the floor of the tunnel. • Nine tendons run through the tunnel: the 4 FDS, the 4 FDP, and FPL. FCR runs in a separate fascial compartment on the radial side of the tunnel.; 1/7/2019
  • 83. Causes and contributing factors in Carpal Tunnel Syndrome  Idiopathic : Most common  Aberrant anatomy -Anomalous flexor tendons -Congenitally small carpal canal -Ganglionic cysts -Lipoma -Proximal lumbrical muscle insertions -Thrombosed artery  Infections  Lyme disease  Mycobacterial infection  Septic arthritis • Inflammatory conditions -Connective tissue disease -gout or pseudogout -Nonspecific tenosynovitis •Metabolic Conditions -Acromegaly -Amyloidosis -Diabetes Mellitus -Hypothyroidism or Hyperthyroidism •Increased canal volume -Congestive heart failure -Oedema -Obesity -Pregnancy •Repetitive wrist movements:Typists & Computer users 1/7/2019
  • 84. Symptoms  Hand and wrist Pain  Paraesthesia  Hypoaesthsia  Sparing of Palmar cutaneous branch supply  Patient wakes at night with burning or aching pain and shakes the hand to obtain relief and restore sensation  Aggravated by elevation of hand  Difficulty in holding on to a glass or cup securely  Thenar atrophy and weakness of thumb opposition and abduction may develop late 1/7/2019
  • 85. Carpal Tunnel Syndrome MNEMONIC PRAGMATIC  P-PREGNANCY  R-RHEUMATOID ARTHRITIS  A-ATHRITIS DEGENERATIVE  G-GROWTH HORMONE EXCESS i.e. ACROMEGALY  M-METABOLIC i.e. GOUT  A-ALCOHOLISM T-TUMORS  I-IDIOPATHIC  C-CONNECTIVETISSUE DISORDER i.e. AMYLOIDOSIS 1/7/2019
  • 86. Pathophysiology of CTS Night numbness is caused by a number of factors: • Horizontal position results in a redistribution of fluid to the upper limbs • Drainage by the action of the muscle pump is diminished •There is a tendency towards wrist flexion at night •The blood pressure drops during late night and early morning, resulting in decreased perfusion pressure 1/7/2019
  • 87. Diagnosis  History  Clinical examination: -Thenar wasting - Phalen’s sign -Tinel’s sign - Carpal compression test  Electro Diagnostic Studies: -Very reliable for evaluation - Atypical cases may be present 1/7/2019
  • 88. Signs of CTS  Thenar muscle wasting due to continued pressure 1/7/2019
  • 89. Phalen’s test  Phalen’s test Patients is asked to actively place the wrist in complete but forced flexion +ve if tingling and numbness is produced in 60 sec. Sensitive and specific in 80% 1/7/2019
  • 90. Median Compression test/ Durkan’s test  Median nerve compression test Direct pressure is exerted over both wrist 1st phase –time taken for symptoms appear(15- 20sec) 2nd phase-time taken for symptoms to disappear after release of pressure 1/7/2019
  • 91.  Tourniquet test BP cuff tied proximal to elbow and inflated higher than patient’s Systolic BP. +ve if numbness and paraesthesia 1/7/2019
  • 92. Treatment  CONSERVATIVETREATMENTS -General measures -Oral medications -Local injection -Wrist splints  Surgical decompression: Division of the transverse carpal ligament - Open - Endoscopic 1/7/2019
  • 93. ORAL MEDICATIONS • Diuretics • Nonsteroidal anti-inflammatory drugs (NSAIDs) •Thiamime (Vitamin B1)pyridoxine (vitamin B6) Cyanocobalamin(Vitamin B12) • Orally administered corticosteroids ▫ Prednisolone ▫ 20 mg per day for two weeks ▫ followed by 10 mg per day for two weeks 1/7/2019
  • 94. Steroid Injection •Transient relief occurs in 80% of patients after steroid injection • But only 22% of patients with steroid injections are pain free at 12 months  (These patients were also splinted). – It is most useful early in the disease, when there has been less than 1yr of symptoms – there is no weakness or thenar atrophy •Technique of injection: – a 22-gauge needle is introduced between FCR and PL – angled dorsally and distally at 45 degrees – It is advanced until it reaches the floor of the tunnel, and then withdrawn 5mm – A water soluble preparation is used • e.g. dexamethasone acetate plus lignocaine • if any immediate paraesthesias occur the injection is stopped. 1/7/2019
  • 95. Orthoses  The following orthoses help manage the carpal tunnel syndrome pain: –Wrist hand orthosis –Thumb spica splint – Cock-up wrist splint 1/7/2019
  • 96. Orthotics goals  Decrease pain and swelling  Prevent deformity progression  Prevent Movement  By restrict flexion movement of wrist  Main objective is to position wrist in neutral but preferably slight extension to get pressure off of median nerve 1/7/2019
  • 97. SURGERY  Should be considered in patients with symptoms that do not respond to conservative measures and in patients with severe nerve entrapment as evidenced by nerve conduction studies,thenar atrophy, or motor weakness. • It is important to note that surgery may be effective even if a patient has normal nerve conduction studies Methods of Surgery  Open CarpalTunnel Release – Open technique – Limited incision technique  Endoscopic CarpalTunnel Release 1/7/2019
  • 98. Open Carpal Tunnel Release 1/7/2019
  • 99. Endoscopic Carpal Tunnel Release 1/7/2019
  • 100. Complications Of Surgery  Early –Transection of the median nerve or the superficial arch – Haematoma – Pain, swelling and stiffness – Recurrent Branch injury – Infection •Late – RSD – Hypertrophic scar – Median nerve neuritis – Palmar fasciitis – Fibrosis of carpal tunnel – Recurrence •Revision carpal tunnel release – Only 25% of patients have complete relief of symptoms. 25% have no relief.The rest have partial relief.1/7/2019
  • 101. Postoperative course and results for Open CTR  Grip strength returns to normal in 3 months.  Surgery is most successful when done early; Patients with intermittent numbness do better than patients with constant numbness.  Overall excellent results in 80% (Mayo clinic). 5% have worsened function.  MRI shows a 20-30% increase in the carpal tunnel volume after surgery. MRI also shows that Guyon’s canal enlarges after carpal tunnel release.  Measurement of pressures within the carpal tunnel before and after release demonstrate marked decreases in resting pressures after release of the ligament. 1/7/2019
  • 102. Differential Diagnoses of CTS  Tendonitis  Tenosynovitis  Diabetic neuropathy  Kienbock's disease  Compression of the Median nerve at the elbow 1/7/2019
  • 103. Pronator Syndrome - Proximal Forearm Compression - Because Of :-  ligament of Struthers,  lacertus fibrosus,  pronator teres muscle 1/7/2019
  • 104. Symptoms & signs  Symptoms are similar to those of carpal tunnel syndrome  Sensory disturbances -Thumb & Index > Middle finger  Night pain is unusual and forearm pain is more common  Hand numbness on gripping  Phalen’s test negative  Symptoms provoked by resisted elbow flexion with forearm supinated ( tightening of bicipital aponeurosis )  By resisted forearm pronation with the elbow extended ( pronator tension ) 1/7/2019
  • 105. Same Symptoms As C.T.S But Could Be Differentiated By  include the distribution of the palmar cutaneous nerve  TheTinel sign is positive at the forearm level  The Phalen maneuver does not provoke symptoms  Patients may experience pain with resistance to contraction of the pronator teres or flexor digitorum superficialis 1/7/2019
  • 106. Management  No relief with steroids  Surgical decompression 1/7/2019
  • 107. Anterior Interosseous Syndrome  Damage to the Anterior Interosseous Nerve  Causes •Tentinous origin of flexor digitorum •Pronater teres •Tendons from flexor digitorum to flexor policis longus •Accessory head of flexor policis longus (gantzer muscle) •Aberrant radial artery •Thrombosis of ulnar colleteral artery •VIC 1/7/2019
  • 108. Anterior Interosseous Syndrome  Pain in the forearm  Weakness of the gripping movement of the thumb and index finger( unable to make ok sign )  Clinical Findings -inability to flex either the thumb interphalangeal joint or the index-finger distal interphalangeal joint -In contrast to those with pronator syndrome, these patients do not complain of numbness or pain 1/7/2019
  • 109. Anterior Interosseous Syndrome Management Corticosteroids Surgery: - Resection/detachment of deep head of PT 1/7/2019