Dominic D'Agostino

Tampa/St. Petersburg, Florida Area United States

Assistant Professor, Univ. South Florida; Research Scholar at IHMC

Education

Our laboratory develops and tests metabolic therapies, including calorie restriction, ketogenic diets and ketogenic agents for CNS oxygen toxicity (seizures), epilepsy, metabolic disorders, Alzheimer's disease, ALS, muscle wasting and cancer. To investigate the mechanism of these pathologies we use a variety of in vivo and in vitro techniques, including radio-telemetry (EEG, EMG), electrophysiology, fluorescence microscopy, confocal microscopy, atomic force microscopy (AFM), biochemical assays, in vivo bioluminescence imaging, behavioral testing and exercise performance. We have adapted many of these techniques for use inside hyperbaric chambers, which allows us to manipulate oxygen conce...