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The first lecture from the Machine Learning course series of lectures. The lecture covers basic principles of machine learning, such as the difference between supervised and unsupervised learning, several classifiers: nearest neighbour (k-NN), decision trees, random forest, major obstacles in machine learning: overfitting and the curse of dimensionality, followed by cross-validation algorithm and general ML pipeline. A link to my github (https://github.com/skyfallen/MachineLearningPracticals) with practicals that I have designed for this course in both R and Python. I can share keynote files, contact me via e-mail: firstname.lastname@example.org.