5. 1763 , Ingleses usaron contra los indios norteamericanos mantas impregnadas de viruela
6.
7. 1942, los ingleses utilizaron bombas de ántrax en la isla de Gruinard (Escocia). 1979, Sverdlovsk (Unión Soviética), epidemia de ántrax pulmonar. (accidente).
Greetings/Welcome……..on behalf of CDC, I’d like to welcome you This 1 1/2 hr presentation can be summarized with one word: “ BIOSAFETY” Recommend that audience perform a “RISK ASSESSMENT” of their laboratory to identify those procedures/ methods that have the potential of producing aerosols. With subsequent recommendations to either eliminate or minimize those procedures. Additionally, consider moving any of these procedures into the BSC. The 4th ed of BMBL (Biosafety in Microbiological and Biomedical Laboratories) has a nice section on “how to perform a risk assessment, p76. The last slide has the web-site for this document (www.cdc.gov/od/ohs): od stands for Office of the Director and ohs stands for Office of Health and Safety Now, let’s meet the “real experts”……S2 ( legend for slide (starting @ 9 o’clock, going clockwise): B anthracis; Clostridium sp; EM of smallpox virion; and blood smear with brucella.
Anthrax…..a disease of antiquity Exodus 9:3, the fifth plague is thought by some experts to be a description of anthrax In 1877, anthrax was the first disease PROVEN to be a caused by a specific bacterium (Koch) Speaker’s info: The other plagues: water to blood, frogs, flies, lice…..anthrax, …… boils, hail/fire, locust, darkness, and the Passover
Note: the infective dose may vary from 8,000 to 50,000, depending who you read. In the handout, Table 1, we’ve listed 50,000.
BULLET 1: Sputum will have a low recovery…again, inhalation anthrax is a mediastinitis and not a pneumonia BULLET 2: Vesicles…most likely form to actually seen the bacilli on a gram stain BULLET 3: Stool…..forget recovering B anthracis…. Next to the cutaneous forms, blood will be the most likely source for recovery