1. Beyond Calcium: Maintaining Healthy Bones as We Age

2. What do Bones Need? Nutrition? Hormone Regulation? Physical Activity? Medications? Improved Sleep? Dietary Changes?

4. Menopause and Andropause Loss of HPG axis (normal physiology) Compensation through adrenal function Hormonal surges from dysregulation Cytokine production (IL-6) *Inflammation* Cellular cytokine receptors increase Amplitude of response increases Create hormone spikes Decrease glutathione output (antioxidant) Disrupting nitric oxide balance Prostaglandin E-2 increases “Barriers” begin to leak (Brain, Lungs, Gut, Skin)

5. Hormone Imbalance

6. Endocr Rev. 2002 Feb;23(1):90-119.Changes in proinflammatory cytokine activity after menopause. Estrogen-cytokine regulation of bone resorption.

8. Hormone Imbalance

11. Mineral Transport for Hormone and Neurotransmitter Health Minerals from diet/supplements Vitamin D Essential Fatty Acids (Omega’s)