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Femoral Shaft Fractures
Robert F. Ostrum, MD
Cooper Hospital / University Medical Center
Camden, New Jersey
Femur Fractures
• Common injury due to major violent trauma
• 1 femur fracture/ 10,000 people
• More common in people < 25 yo or >65 yo
• Femur fracture leads to reduced activity for 107
days, the average length of hospital stay is 25 days
• Motor vehicle, motorcycle, auto-pedestrian,
aircraft, and gunshot wound accidents are most
frequent causes
Anatomy
• Long tubular bone, anterior bow, flair at femoral
condyles
• Blood supply
– Metaphyseal vessels
– Single nutrient artery in diaphysis enters through the
linea aspera
– Nutrient artery communicates with medullary arteries
in intramedullary canal
– Medullary arteries supply 2/3 of endosteal blood
supply
Blood Supply
• Reaming destroys intramedullary endosteal blood
supply
• Periosteal blood flow increases
• Medullary blood supply is
re-established over 8-12
weeks if spaces left in
canal by implant
• Unreamed intramedullary nailing decreases blood
flow less; restoration of endosteal blood flow earlier
but equal to reamed canal at 12 weeks
Femur Fracture
Classification
• Type 0 - No comminution
• Type 1 - Insignificant butterfly fragment
with transverse or short oblique fracture
• Type 2 - Large butterfly of less than
50% of the bony width, > 50% of cortex
intact
• Type 3 - Larger butterfly leaving less
than 50% of the cortex in contact
• Type 4 - Segmental comminution
» Winquist and Hansen 66A,
1984
Axial and
rotational
stability
Femur Fracture Management
• Piriformis fossa intact, lesser
trochanter intact
• Can you nail this ?
• Should you nail this ?
Femur Fracture
Management
• Initial traction with portable traction splint
or transosseous pin and balanced
suspension
• Evaluation of knee to determine pin
placement
• Timing of surgery is dependent on:
– Resuscitation of patient
– Other injuries - abdomen, chest, brain
– Isolated femur fracture
Bending moment = F x DF = Force
D
D = distance
from force to
implant
F = Force
D
The bending moment
for the plate is greater
due to the force being
applied over a larger
distance
IM
Nail
Plate
Femur Fracture
Management
• Diaphyseal fractures are managed by
intramedullary nailing through an antegrade
or retrograde insertion site
• Proximal or distal 1/3 fractures MAY be
managed best with a plate or an
intramedullary nail depending on the
location and morphology of the fracture
Femoral IM Nailing
To Ream ?
Hypothesis:
Femoral reaming increases fatty emboli to the
lungs and potentially increases pulmonary
complications
Femur Fracture
Reaming
• Reaming advantages:
– Nail will not get incarcerated
– Higher union rates
– More durable fracture/nail construct
– Earlier weight bearing
• Unreamed nails - still generate fat embolism with
opening of piriformis fossa and probably higher
pressure with unreamed nail insertion
Femur Fracture
Reaming
• Reaming of the femoral shaft fracture
– Multiple studies demonstrate that the thoracic
injury is the major determinant of pulmonary
complications, NOT the use of a reamed IM
nail
• Charash J Trauma 1994
• Van Os J Trauma 1994
• Ziran J Trauma 1997
• Bone Clin Orthop 1998
• Bosse JBJS 79A 1997
Femur Fracture
Reaming
• Reaming of the femoral shaft fracture
– Only Pape (J Trauma 1993) has shown a
deleterious pulmonary effect to immediate
reamed intramedullary nailing in acute femur
fracture patients with pulmonary trauma
– In both a retrospective analysis and multiple
animal studies (Pape , J Trauma 1992)
– However, other animal studies refute these results
• Wolinsky, J Orthop Tr 1998
• Duwelius, JBJS 79A 1997
Comparison of Reamed vs Unreamed IM Nails
224 patients
Risk of nonunion was 5x greater in unreamed group
80% of nonunions could have been prevented by reaming
NO increase in
ARDS with
reaming !!
Powell et al, OTA
1999, 2000
Conclusion:
REAM
Femur Fracture
Management
• Antegrade nailing is still the gold standard
– Highest union rates with reamed nails
– Extraarticular starting point
– Refined technique
• Antegrade nailing problems:
– Varus alignment of proximal fractures
– Trendelenburg gait
– Can be difficult with obese or multiply injured patients
Antegrade Femoral Nailing
starting point
Caution !! anterior
Caution !! Anterior
starting point leads to
increased proximal
femur stresses
Antegrade Femoral Nailing
starting point
Posterior -
loss of
proximal
fixation
Piriformis
fossa- proper
starting point
Anterior - generates
huge forces, can lead
to bursting of
proximal femur
Femur Fractures
Gluteal muscles
Iliopsoas leads to
flexion of the
proximal fragment
Adductor
muscles
shorten the
femur
These muscle forces
must be overcome to
reduce and
intramedullary nail
the femur
Static Locking of All
Femoral IM Nails !!!
• Brumback- 1988
– 98% union with Statically Locked Rod
Immediate Weight Bearing
• Mythical 70 Kg Man
– Axial Load to Failure 300%
• 75% Stiffness in Bending
• 50% Stiffness in torsion
– Withstand 500,000 cycle at
loads of 3X body
– 28 Winquist type 4 fractures
• 27 Healed primarily
• No Locking Bolt or Rod Fatigue
» Brumback JBJS 1999
Femur Fracture
Management
• Retrograde nailing has advantages
– Easier in large patients to find starting point
– Better for combined fracture patterns (ipsilateral
femoral neck, tibia,acetabulum)
– Union approaching antegrade nails when reamed
• Retrograde nailing has its problems:
– Union rates are slightly lower, more dynamizing
with small diameter nails
– Intra-articular starting point
Retrograde Femoral Nailing
Starting Point
Mean Contact Area
0
20
40
60
80
100
120
140
160
180
200
90 degrees 120 degrees
Control
In
Flush
Out
Maximum Pressure
0
1
2
3
4
5
6
7
90 degrees 120 degrees
Contol
In
Flush
Out
* p < 0.05
* p < 0.05
Only with the nail 1 mm prominent were the
patellofemoral pressures increased
Retrograde Femoral Nailing
• A cadaveric study using Fuji film
demonstrated NO deleterious effects on the
patello-femoral joint with a properly
inserted retrograde IM nail
• The orthopaedic literature does NOT
support decreased knee motion or increase
knee pain with a retrograde nail
Retrograde IM Nail
Femur Fractures
• 42 yo male C2 femur, Gr 2 open ipsilateral tibia fx
Retrograde IM Nail Femur Fractures
• Immediate post-op with treatment through a
limited 4cm knee incision
Femur Fracture
Management
• Retrograde Nailing
– Union rates lower with unreamed nails
– Higher dynamization with non canal sized nails
– Better union rates equal to antegrade with reamed canal
sized nails
• Moed JBJS 1995, J Orthop Trauma 1998
• Ostrum J Orthop Trauma 1998, 2000
– Advantages for ipsilateral acetabulum or femoral neck
and shaft fracture, floating knees, obese patients,
supracondylar fractures including those around total
knee replacements
Retrograde Nailing is Beneficial
for Floating Knee Injuries
Retrograde Nail:
Long or Short ?
• 9 human matched cadaver femurs, gap
model
• 36 cm vs 20 cm
• Coronal and sagittal testing
• 75 Newtons applied in 3 point bending
• Locked with 1 or 2 proximal screws
Retrograde Nail:
Long or Short ?
20cm 36cm
2 prox,sagittal 7.2* 1.8*
2 prox,coronal 6.3 4.3
1 prox,sagittal 7.6* 2.2*
1 prox,coronal 13.6* 4.4*
Longer nails provide improved stability !!!
* statistically significant at p<0.05
Femur Fracture
Technique
• Antegrade Intramedullary Nailing
– Supine - better for multiply injured patients
– Lateral - easier piriformis fossa starting point,
difficult set up, rotation concerns
– Without a fracture table
• Retrograde Intramedullary Nailing
– Supine - flex the knee 50° to allow access to
Blumensaat’s line
Antegrade v Retrograde
Comparisons
Equal union rates
Tornetta, JBJS (B), 2000
Ricci, JOT, 2001
Ostrum, JOT, 2000
• ANTEGRADE
– More hip and
proximal thigh pain
– Greater incidence of
Trendelenburg gait
• RETROGRADE
– More symptomatic distal
hardware
– Higher dynamization rates
with small diameter nails
Femur Fracture
Complications
• Hardware failure
• Nonunion - less than 1-2%
• Malunion - shortening, malrotation,
angulation
• Infection
• Neurologic, vascular injury
• Heterotopic ossification
Femur Fracture
Nonunion
Femoral
nonunion
with
broken IM
Nail
Union after
exchange,
reamed
IM nail
Hypertrophic Nonunion
• Problem with smaller diameter nails
• Don’t Dynamize EXCHANGE !!
• Has a blood supply, WANTS MORE
STABILITY
Open Femur Fracture
Antegrade IM Nail is Safe
• Reamed , Antegrade Intramedullary Nailing
has been shown to be effective
• A high union rate, low complications
• Perhaps stage Grade 3B fractures after
debridement and skeletal traction
– Brumback, JBJS 71A, 1989
– Lhowe, Hansen JBJS 70A, 198
Femur Fracture
Subtrochanteric Fracture Management
• Possible to perform intramedullary nail if
the piriformis fossa is intact
• Choice of nail type depends on if the lesser
trochanter is intact
• Varus seen with proximal femur
intramedullary nailing
• Plating is also an option with/without an
intact starting point
Subtrochanteric
fractures are from the
base of the lesser
trochanter to 5 cm distal
Low Subtroch Fx’s
Most low subtrochanteric
fractures with an intact
piriformis fossa can be treated
with a 1st gen IM Nail
When piriformis fossa is not
involved and the lesser
trochanter is fractured, a 2nd
generation nail may be used
Nail or… Plate
Indirect
Reduction:
Technique
Indirect
Reduction
Step 1- Approximate
closed reduction with
fracture table in BOTH
planes
Step 2 - Percutaneous
insertion of guide pins
Step 3 -
Placement of
lag screw and
percutaneous
plate placement
Head
Knee
Indirect
Reduction
Step 4 - Final
reduction with
percutaneous screw
placement
Push up to prevent sag
head
knee
Screw Placement
Final films after percutaneous
Indirect Reduction of a
Subtrochanteric femur fracture
Ipsilateral Femoral Neck & Shaft
Fractures
• Optimum fixation of the femoral neck should be
the goal
• Varus malunion of the femoral neck is not
uncommon, osteotomies can lead to poor results
• Vertical femoral neck fracture seen in 26-59% of
cases (Pauwel’s angle > 70°)
• Rate of avascular necrosis is low, 3%, even when
missed
Ipsilateral Femoral Neck
& Shaft Fractures
• Type 1 - nondisplaced
femoral neck/hip
fractures
• When found prior to
nailing can be treated
with screws or a
sliding hip screw then
retrograde or
antegrade nail
Ipsilateral Femoral
Neck & Shaft Fractures
• Type 2 - missed femoral
neck fracture
• Insertion of screws around
the nail
• Low AVN rate even when
missed
• Vertical fractures not
iatrogenic
Ipsilateral Femoral Neck
& Shaft Fractures
• Type 3 - displaced femoral neck fractures
• Treat with implant appropriate for neck fracture FIRST
• Treat femoral shaft fracture with retrograde nail
Femoral Shaft Fracture with
Vascular Injury
• Quick external fixation with restoration of
length
• Fasciotomies
Femoral Shaft Fracture with
Vascular Injury
• Exchange femoral nail either in same
setting or in a few days
• When found early plating or rodding of
femur is rarely possible first
• Do NOT perform IM nailing after arterial
repair without initial length restoration
IM Nailing of the Femoral Shaft
• Choice TO nail depends on fracture
configuration, especially at proximal and
distal ends
• Choice OF nail depends on fracture
location, associated musculoskeletal
injuries, obesity
• Think before IM Nailing of femur
Return to
Lower Extremity
Index

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L04 femur shaft, st fx

  • 1. Femoral Shaft Fractures Robert F. Ostrum, MD Cooper Hospital / University Medical Center Camden, New Jersey
  • 2. Femur Fractures • Common injury due to major violent trauma • 1 femur fracture/ 10,000 people • More common in people < 25 yo or >65 yo • Femur fracture leads to reduced activity for 107 days, the average length of hospital stay is 25 days • Motor vehicle, motorcycle, auto-pedestrian, aircraft, and gunshot wound accidents are most frequent causes
  • 3. Anatomy • Long tubular bone, anterior bow, flair at femoral condyles • Blood supply – Metaphyseal vessels – Single nutrient artery in diaphysis enters through the linea aspera – Nutrient artery communicates with medullary arteries in intramedullary canal – Medullary arteries supply 2/3 of endosteal blood supply
  • 4. Blood Supply • Reaming destroys intramedullary endosteal blood supply • Periosteal blood flow increases • Medullary blood supply is re-established over 8-12 weeks if spaces left in canal by implant • Unreamed intramedullary nailing decreases blood flow less; restoration of endosteal blood flow earlier but equal to reamed canal at 12 weeks
  • 5. Femur Fracture Classification • Type 0 - No comminution • Type 1 - Insignificant butterfly fragment with transverse or short oblique fracture • Type 2 - Large butterfly of less than 50% of the bony width, > 50% of cortex intact • Type 3 - Larger butterfly leaving less than 50% of the cortex in contact • Type 4 - Segmental comminution » Winquist and Hansen 66A, 1984 Axial and rotational stability
  • 6. Femur Fracture Management • Piriformis fossa intact, lesser trochanter intact • Can you nail this ? • Should you nail this ?
  • 7. Femur Fracture Management • Initial traction with portable traction splint or transosseous pin and balanced suspension • Evaluation of knee to determine pin placement • Timing of surgery is dependent on: – Resuscitation of patient – Other injuries - abdomen, chest, brain – Isolated femur fracture
  • 8. Bending moment = F x DF = Force D D = distance from force to implant F = Force D The bending moment for the plate is greater due to the force being applied over a larger distance IM Nail Plate
  • 9. Femur Fracture Management • Diaphyseal fractures are managed by intramedullary nailing through an antegrade or retrograde insertion site • Proximal or distal 1/3 fractures MAY be managed best with a plate or an intramedullary nail depending on the location and morphology of the fracture
  • 10. Femoral IM Nailing To Ream ? Hypothesis: Femoral reaming increases fatty emboli to the lungs and potentially increases pulmonary complications
  • 11. Femur Fracture Reaming • Reaming advantages: – Nail will not get incarcerated – Higher union rates – More durable fracture/nail construct – Earlier weight bearing • Unreamed nails - still generate fat embolism with opening of piriformis fossa and probably higher pressure with unreamed nail insertion
  • 12. Femur Fracture Reaming • Reaming of the femoral shaft fracture – Multiple studies demonstrate that the thoracic injury is the major determinant of pulmonary complications, NOT the use of a reamed IM nail • Charash J Trauma 1994 • Van Os J Trauma 1994 • Ziran J Trauma 1997 • Bone Clin Orthop 1998 • Bosse JBJS 79A 1997
  • 13. Femur Fracture Reaming • Reaming of the femoral shaft fracture – Only Pape (J Trauma 1993) has shown a deleterious pulmonary effect to immediate reamed intramedullary nailing in acute femur fracture patients with pulmonary trauma – In both a retrospective analysis and multiple animal studies (Pape , J Trauma 1992) – However, other animal studies refute these results • Wolinsky, J Orthop Tr 1998 • Duwelius, JBJS 79A 1997
  • 14. Comparison of Reamed vs Unreamed IM Nails 224 patients Risk of nonunion was 5x greater in unreamed group 80% of nonunions could have been prevented by reaming NO increase in ARDS with reaming !! Powell et al, OTA 1999, 2000 Conclusion: REAM
  • 15. Femur Fracture Management • Antegrade nailing is still the gold standard – Highest union rates with reamed nails – Extraarticular starting point – Refined technique • Antegrade nailing problems: – Varus alignment of proximal fractures – Trendelenburg gait – Can be difficult with obese or multiply injured patients
  • 16. Antegrade Femoral Nailing starting point Caution !! anterior Caution !! Anterior starting point leads to increased proximal femur stresses
  • 17. Antegrade Femoral Nailing starting point Posterior - loss of proximal fixation Piriformis fossa- proper starting point Anterior - generates huge forces, can lead to bursting of proximal femur
  • 18. Femur Fractures Gluteal muscles Iliopsoas leads to flexion of the proximal fragment Adductor muscles shorten the femur These muscle forces must be overcome to reduce and intramedullary nail the femur
  • 19. Static Locking of All Femoral IM Nails !!! • Brumback- 1988 – 98% union with Statically Locked Rod
  • 20. Immediate Weight Bearing • Mythical 70 Kg Man – Axial Load to Failure 300% • 75% Stiffness in Bending • 50% Stiffness in torsion – Withstand 500,000 cycle at loads of 3X body – 28 Winquist type 4 fractures • 27 Healed primarily • No Locking Bolt or Rod Fatigue » Brumback JBJS 1999
  • 21. Femur Fracture Management • Retrograde nailing has advantages – Easier in large patients to find starting point – Better for combined fracture patterns (ipsilateral femoral neck, tibia,acetabulum) – Union approaching antegrade nails when reamed • Retrograde nailing has its problems: – Union rates are slightly lower, more dynamizing with small diameter nails – Intra-articular starting point
  • 23. Mean Contact Area 0 20 40 60 80 100 120 140 160 180 200 90 degrees 120 degrees Control In Flush Out
  • 24. Maximum Pressure 0 1 2 3 4 5 6 7 90 degrees 120 degrees Contol In Flush Out * p < 0.05 * p < 0.05 Only with the nail 1 mm prominent were the patellofemoral pressures increased
  • 25. Retrograde Femoral Nailing • A cadaveric study using Fuji film demonstrated NO deleterious effects on the patello-femoral joint with a properly inserted retrograde IM nail • The orthopaedic literature does NOT support decreased knee motion or increase knee pain with a retrograde nail
  • 26. Retrograde IM Nail Femur Fractures • 42 yo male C2 femur, Gr 2 open ipsilateral tibia fx
  • 27. Retrograde IM Nail Femur Fractures • Immediate post-op with treatment through a limited 4cm knee incision
  • 28. Femur Fracture Management • Retrograde Nailing – Union rates lower with unreamed nails – Higher dynamization with non canal sized nails – Better union rates equal to antegrade with reamed canal sized nails • Moed JBJS 1995, J Orthop Trauma 1998 • Ostrum J Orthop Trauma 1998, 2000 – Advantages for ipsilateral acetabulum or femoral neck and shaft fracture, floating knees, obese patients, supracondylar fractures including those around total knee replacements
  • 29. Retrograde Nailing is Beneficial for Floating Knee Injuries
  • 30. Retrograde Nail: Long or Short ? • 9 human matched cadaver femurs, gap model • 36 cm vs 20 cm • Coronal and sagittal testing • 75 Newtons applied in 3 point bending • Locked with 1 or 2 proximal screws
  • 31. Retrograde Nail: Long or Short ? 20cm 36cm 2 prox,sagittal 7.2* 1.8* 2 prox,coronal 6.3 4.3 1 prox,sagittal 7.6* 2.2* 1 prox,coronal 13.6* 4.4* Longer nails provide improved stability !!! * statistically significant at p<0.05
  • 32. Femur Fracture Technique • Antegrade Intramedullary Nailing – Supine - better for multiply injured patients – Lateral - easier piriformis fossa starting point, difficult set up, rotation concerns – Without a fracture table • Retrograde Intramedullary Nailing – Supine - flex the knee 50° to allow access to Blumensaat’s line
  • 33. Antegrade v Retrograde Comparisons Equal union rates Tornetta, JBJS (B), 2000 Ricci, JOT, 2001 Ostrum, JOT, 2000 • ANTEGRADE – More hip and proximal thigh pain – Greater incidence of Trendelenburg gait • RETROGRADE – More symptomatic distal hardware – Higher dynamization rates with small diameter nails
  • 34. Femur Fracture Complications • Hardware failure • Nonunion - less than 1-2% • Malunion - shortening, malrotation, angulation • Infection • Neurologic, vascular injury • Heterotopic ossification
  • 36. Hypertrophic Nonunion • Problem with smaller diameter nails • Don’t Dynamize EXCHANGE !! • Has a blood supply, WANTS MORE STABILITY
  • 37. Open Femur Fracture Antegrade IM Nail is Safe • Reamed , Antegrade Intramedullary Nailing has been shown to be effective • A high union rate, low complications • Perhaps stage Grade 3B fractures after debridement and skeletal traction – Brumback, JBJS 71A, 1989 – Lhowe, Hansen JBJS 70A, 198
  • 38. Femur Fracture Subtrochanteric Fracture Management • Possible to perform intramedullary nail if the piriformis fossa is intact • Choice of nail type depends on if the lesser trochanter is intact • Varus seen with proximal femur intramedullary nailing • Plating is also an option with/without an intact starting point
  • 39. Subtrochanteric fractures are from the base of the lesser trochanter to 5 cm distal
  • 40. Low Subtroch Fx’s Most low subtrochanteric fractures with an intact piriformis fossa can be treated with a 1st gen IM Nail
  • 41. When piriformis fossa is not involved and the lesser trochanter is fractured, a 2nd generation nail may be used
  • 44. Indirect Reduction Step 1- Approximate closed reduction with fracture table in BOTH planes Step 2 - Percutaneous insertion of guide pins
  • 45. Step 3 - Placement of lag screw and percutaneous plate placement Head Knee
  • 46. Indirect Reduction Step 4 - Final reduction with percutaneous screw placement Push up to prevent sag
  • 48. Final films after percutaneous Indirect Reduction of a Subtrochanteric femur fracture
  • 49. Ipsilateral Femoral Neck & Shaft Fractures • Optimum fixation of the femoral neck should be the goal • Varus malunion of the femoral neck is not uncommon, osteotomies can lead to poor results • Vertical femoral neck fracture seen in 26-59% of cases (Pauwel’s angle > 70°) • Rate of avascular necrosis is low, 3%, even when missed
  • 50. Ipsilateral Femoral Neck & Shaft Fractures • Type 1 - nondisplaced femoral neck/hip fractures • When found prior to nailing can be treated with screws or a sliding hip screw then retrograde or antegrade nail
  • 51. Ipsilateral Femoral Neck & Shaft Fractures • Type 2 - missed femoral neck fracture • Insertion of screws around the nail • Low AVN rate even when missed • Vertical fractures not iatrogenic
  • 52. Ipsilateral Femoral Neck & Shaft Fractures • Type 3 - displaced femoral neck fractures • Treat with implant appropriate for neck fracture FIRST • Treat femoral shaft fracture with retrograde nail
  • 53. Femoral Shaft Fracture with Vascular Injury • Quick external fixation with restoration of length • Fasciotomies
  • 54. Femoral Shaft Fracture with Vascular Injury • Exchange femoral nail either in same setting or in a few days • When found early plating or rodding of femur is rarely possible first • Do NOT perform IM nailing after arterial repair without initial length restoration
  • 55. IM Nailing of the Femoral Shaft • Choice TO nail depends on fracture configuration, especially at proximal and distal ends • Choice OF nail depends on fracture location, associated musculoskeletal injuries, obesity • Think before IM Nailing of femur Return to Lower Extremity Index