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INTRODUCTION
MENDEL’S EXPERIMENT: MONOHYBRID CROSS
MONOHYBRID CROSS
MONOHYBRID CROSS USING FLOWER COLOUR AS A
CHARACTER
TEST CROSS
TEST CROSS TO KNOW THE GENOTYPE OF THE
PARENT
TEST CROSS
FEW EXERCISES
PHENOTYPE RED FLOWER WHITE FLOWER
GENOTYPE RR X rr
GAMETES
F1 Rr
PHENOTYPE
GAMETES
F1 SELFED Rr X Rr
R r
R r
R r
R r
R RR
Red
Rr
Red
r Rr
Red
rr
White
Phenotypic ratio : 3 red : 1 white
3 : 1
Genotypic ratio : 1 RR : 2 Rr : 1 rr
1 : 2 : 1
FEW EXERCISES
• CROSS BETWEEN
• ROUND SEEDS & WRINKLED SEED (ROUND IS DOMINANT OVER WRINKLED)
• YELLOW SEEDS X GREEN SEEDS (YELLOW IS DOMINANT OVER GREEN)
• AXIAL FLOWER X TERMINAL FLOWER (AXIAL DOMINANT OVER TERMINAL)
FEW EXERCISES
PHENOTYPE ROUNDSEED WRINKLED SEED
GENOTYPE RR X rr
GAMETES
F1 Rr
PHENOTYPE round seed
GAMETES
F1 SELFED Rr X Rr
r
R r
R
R r
R RR
Round
Rr
Round
r Rr
round
rr
Wrinkled
Phenotypic ratio : 3 round : 1 wrinkled
3 : 1
Genotypic ratio : 1 : 2: 1
FEW EXERCISES
PHENOTYPE YELLOW SEED GREEN SEED
GENOTYPE YY X yy
GAMETES
F1 Yy
PHENOTYPE
GAMETES
F1 SELFED Yy X Yy
y
Y y
Y
Y y
Y YY
Yellow
Yy
yellow
y Yy
yellow
yy
Green
Phenotypic ratio : 3 yellow : 1 green
3 : 1
Genotypic ratio :1 : 2 :1
Y Yy y
FEW EXERCISES
PHENOTYPE AXIAL FLOWER TERMINAL FLOWER
GENOTYPE AA X aa
GAMETES
F1 Aa
PHENOTYPE
GAMETES
F1 SELFED Aa X Aa
A a
A a
A a
A AA
Axial
Aa
Axial
a Aa
Axial
aa
Terminal
Phenotypic ratio : 3 : 1
Genotypic ratio : 1 :2 : 1
A Aa a
DIHYBRID CROSS
DIHYBRID CROSSY Y
R R
y y
r r
Y
R
y
r
Y
r
y
R
y
r
Y
R
DIHYBRID CROSS
FEW EXERCISES
• TALL RED (HOMOZYGOUS DOMINANT] WITH SHORT WHITE [HOMOZYGOUS RECESSIVE]
• AXIAL PURPLE (HOMOZYGOUS DOMINANT) WITH TERMINAL WHITE (HOMOZYGOUS RECESSIVE)
• TALL WHITE (HOMOZYGOUS) CROSS WITH SHORT RED (HOMOZYGOUS) NOTE: TALL IS DOMINANT OVER
SHORT AND RED IS DOMINANT OVER WHITE
FEW EXERCISES
PHENOTYPE TALL RED FLOWER DWARF WHITE FLOWER
GENOTYPE TTRR X ttrr
GAMETES
F1 TtRr
PHENOTYPE
GAMETES
F1 SELFED TtRr X TtRr
TR
TR
tr
TR Tr tR tr
TR TTRR TTRr TtRR TtRr
Tr TTRr TTrr TtRr Ttrr
tR TtRR TtRr ttRR ttRr
tr TtRr Ttrr ttRr ttrr
Phenotypic ratio : 9 tall red : 3 tall white : 3
dwarf red :1 dwarf white
9: 3 : 3 : 1
Tr tR tr
FEW EXERCISES
PHENOTYPE AXIAL PURPLE TERMINAL WHITE
GENOTYPE AAPP X aapp
GAMETES
F1 AaPp
PHENOTYPE
GAMETES
F1 SELFED X
AP
AP Ap aP ap
AP AAPP AAPp AaPP AaPp
Ap AAPp AApp AaPp Aapp
aP AaPP AaPp aaPP aaPp
ap AaPp Aapp aaPp aapp
Phenotypic ratio : 9 AXIAL PURPLE : 3 AXIAL
WHITE : 3 TERMINAL PURPLE : 1 TERMINAL
WHITE
9 : 3 : 3 : 1
ap
AP Ap aP ap
FEW EXERCISES
PHENOTYPE TALL WHITE FLOWER SHORT RED FLOWER
GENOTYPE TTrr X ttRR
GAMETES
F1 TtRr
PHENOTYPE
GAMETES
F1 SELFED TtRr X TtRr
Tr
Phenotypic ratio : 9 : 3 : 3 : 1
Genotypic ratio :
TR Tr tR tr
TR TTRR TTRr TtRR TtRr
Tr TTRr TTrr TtRr TTrr
tR TtRR TtRr ttRR ttRr
tr TtRr Ttrr ttRr ttrr
tR
TR Tr tR tr
MENDEL’S LAW OF INHERITANCE
MENDEL’S LAW OF INHERITANCE
PHENOTYPE ROUND SEED WRINKLED SEED
GENOTYPE RR X rr
GAMETES
F1 Rr
PHENOTYPE round seed
GAMETES
R r
rR
MENDEL’S LAW OF INHERITANCE
PHENOTYPE ROUNDSEED WRINKLED SEED
GENOTYPE RR X rr
GAMETES
F1 Rr
PHENOTYPE round seed
GAMETES R r
rR R r
MENDEL’S LAW OF INHERITANCE
Y
r
y
R
y
r
Y
R
Y
R
y
r
Gametes
Parent genotype
YyRr
DIHYRBID CROSS BETWEEN HETEROZYGOUS PARENTS
PHENOTYPE TALL RED FLOWER SHORT WHITE FLOWER
GENOTYPE TtRr X ttrr
GAMETES
F1
PHENOTYPE
GAMETES
F1 SELFED
TR Tr tr tr
TR Tr tR tr
tr TtRr
Tall
Red
Ttrr
Tall
white
ttRr
Short
red
ttrr
Short
white
tR
IMPORTANCE OF MENDELISM
• Improvement of plants : Hybridization is used for obtaining improved varieties of plants. This process results in
combinations of desirable characters of two or more species or varieties.
• Improvement of animals : Mendelism has enabled the plant breeders to improve the races of domestic animals.
• Improvement of human race : Laws of heredity postulated by Mendel are equally applicable to mankind.
• Disputed parentage : Study of inheritance of the blood group can solve the disputed parentage of a child.
• Genetic Counselling : With the knowledge of Mendelism, genetic counsellor can predict the possibility of
hereditary defect in early foetus
REASONS FOR MENDEL’S SUCCESS
• His choice of plants as pea plants (Pisum sativum) for his breeding experiments was excellent.
• Mendel kept complete record of every cross.
• He also used statistical methods and law of probability for finalising his results.
• Mendel’s predecessors usually studied many traits simultaneously but he took one or two traits at one time for his
experiments.
• Mendel was fortunate that the characters which by chance he selected for his experiments did not show linkage,
incomplete dominance, gene interaction etc.
• He took utmost care to check contamination from foreign pollen at the time of cross breeding.
• Mendel formulated theoretical explanations for interpreting his results. He tested his every explanation for its validity.
• He did not attempt to solve all the variations reported in his breeding experiments, which were not clear to him, such as
linkage.
THANK YOU

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Principles of inheritance & variation II

  • 1.
  • 4.
  • 6. MONOHYBRID CROSS USING FLOWER COLOUR AS A CHARACTER
  • 8. TEST CROSS TO KNOW THE GENOTYPE OF THE PARENT
  • 10. FEW EXERCISES PHENOTYPE RED FLOWER WHITE FLOWER GENOTYPE RR X rr GAMETES F1 Rr PHENOTYPE GAMETES F1 SELFED Rr X Rr R r R r R r R r R RR Red Rr Red r Rr Red rr White Phenotypic ratio : 3 red : 1 white 3 : 1 Genotypic ratio : 1 RR : 2 Rr : 1 rr 1 : 2 : 1
  • 11. FEW EXERCISES • CROSS BETWEEN • ROUND SEEDS & WRINKLED SEED (ROUND IS DOMINANT OVER WRINKLED) • YELLOW SEEDS X GREEN SEEDS (YELLOW IS DOMINANT OVER GREEN) • AXIAL FLOWER X TERMINAL FLOWER (AXIAL DOMINANT OVER TERMINAL)
  • 12. FEW EXERCISES PHENOTYPE ROUNDSEED WRINKLED SEED GENOTYPE RR X rr GAMETES F1 Rr PHENOTYPE round seed GAMETES F1 SELFED Rr X Rr r R r R R r R RR Round Rr Round r Rr round rr Wrinkled Phenotypic ratio : 3 round : 1 wrinkled 3 : 1 Genotypic ratio : 1 : 2: 1
  • 13. FEW EXERCISES PHENOTYPE YELLOW SEED GREEN SEED GENOTYPE YY X yy GAMETES F1 Yy PHENOTYPE GAMETES F1 SELFED Yy X Yy y Y y Y Y y Y YY Yellow Yy yellow y Yy yellow yy Green Phenotypic ratio : 3 yellow : 1 green 3 : 1 Genotypic ratio :1 : 2 :1 Y Yy y
  • 14. FEW EXERCISES PHENOTYPE AXIAL FLOWER TERMINAL FLOWER GENOTYPE AA X aa GAMETES F1 Aa PHENOTYPE GAMETES F1 SELFED Aa X Aa A a A a A a A AA Axial Aa Axial a Aa Axial aa Terminal Phenotypic ratio : 3 : 1 Genotypic ratio : 1 :2 : 1 A Aa a
  • 16. DIHYBRID CROSSY Y R R y y r r Y R y r Y r y R y r Y R
  • 18. FEW EXERCISES • TALL RED (HOMOZYGOUS DOMINANT] WITH SHORT WHITE [HOMOZYGOUS RECESSIVE] • AXIAL PURPLE (HOMOZYGOUS DOMINANT) WITH TERMINAL WHITE (HOMOZYGOUS RECESSIVE) • TALL WHITE (HOMOZYGOUS) CROSS WITH SHORT RED (HOMOZYGOUS) NOTE: TALL IS DOMINANT OVER SHORT AND RED IS DOMINANT OVER WHITE
  • 19. FEW EXERCISES PHENOTYPE TALL RED FLOWER DWARF WHITE FLOWER GENOTYPE TTRR X ttrr GAMETES F1 TtRr PHENOTYPE GAMETES F1 SELFED TtRr X TtRr TR TR tr TR Tr tR tr TR TTRR TTRr TtRR TtRr Tr TTRr TTrr TtRr Ttrr tR TtRR TtRr ttRR ttRr tr TtRr Ttrr ttRr ttrr Phenotypic ratio : 9 tall red : 3 tall white : 3 dwarf red :1 dwarf white 9: 3 : 3 : 1 Tr tR tr
  • 20. FEW EXERCISES PHENOTYPE AXIAL PURPLE TERMINAL WHITE GENOTYPE AAPP X aapp GAMETES F1 AaPp PHENOTYPE GAMETES F1 SELFED X AP AP Ap aP ap AP AAPP AAPp AaPP AaPp Ap AAPp AApp AaPp Aapp aP AaPP AaPp aaPP aaPp ap AaPp Aapp aaPp aapp Phenotypic ratio : 9 AXIAL PURPLE : 3 AXIAL WHITE : 3 TERMINAL PURPLE : 1 TERMINAL WHITE 9 : 3 : 3 : 1 ap AP Ap aP ap
  • 21. FEW EXERCISES PHENOTYPE TALL WHITE FLOWER SHORT RED FLOWER GENOTYPE TTrr X ttRR GAMETES F1 TtRr PHENOTYPE GAMETES F1 SELFED TtRr X TtRr Tr Phenotypic ratio : 9 : 3 : 3 : 1 Genotypic ratio : TR Tr tR tr TR TTRR TTRr TtRR TtRr Tr TTRr TTrr TtRr TTrr tR TtRR TtRr ttRR ttRr tr TtRr Ttrr ttRr ttrr tR TR Tr tR tr
  • 22. MENDEL’S LAW OF INHERITANCE
  • 23. MENDEL’S LAW OF INHERITANCE PHENOTYPE ROUND SEED WRINKLED SEED GENOTYPE RR X rr GAMETES F1 Rr PHENOTYPE round seed GAMETES R r rR
  • 24. MENDEL’S LAW OF INHERITANCE PHENOTYPE ROUNDSEED WRINKLED SEED GENOTYPE RR X rr GAMETES F1 Rr PHENOTYPE round seed GAMETES R r rR R r
  • 25. MENDEL’S LAW OF INHERITANCE Y r y R y r Y R Y R y r Gametes Parent genotype YyRr
  • 26. DIHYRBID CROSS BETWEEN HETEROZYGOUS PARENTS PHENOTYPE TALL RED FLOWER SHORT WHITE FLOWER GENOTYPE TtRr X ttrr GAMETES F1 PHENOTYPE GAMETES F1 SELFED TR Tr tr tr TR Tr tR tr tr TtRr Tall Red Ttrr Tall white ttRr Short red ttrr Short white tR
  • 27. IMPORTANCE OF MENDELISM • Improvement of plants : Hybridization is used for obtaining improved varieties of plants. This process results in combinations of desirable characters of two or more species or varieties. • Improvement of animals : Mendelism has enabled the plant breeders to improve the races of domestic animals. • Improvement of human race : Laws of heredity postulated by Mendel are equally applicable to mankind. • Disputed parentage : Study of inheritance of the blood group can solve the disputed parentage of a child. • Genetic Counselling : With the knowledge of Mendelism, genetic counsellor can predict the possibility of hereditary defect in early foetus
  • 28. REASONS FOR MENDEL’S SUCCESS • His choice of plants as pea plants (Pisum sativum) for his breeding experiments was excellent. • Mendel kept complete record of every cross. • He also used statistical methods and law of probability for finalising his results. • Mendel’s predecessors usually studied many traits simultaneously but he took one or two traits at one time for his experiments. • Mendel was fortunate that the characters which by chance he selected for his experiments did not show linkage, incomplete dominance, gene interaction etc. • He took utmost care to check contamination from foreign pollen at the time of cross breeding. • Mendel formulated theoretical explanations for interpreting his results. He tested his every explanation for its validity. • He did not attempt to solve all the variations reported in his breeding experiments, which were not clear to him, such as linkage.