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ANTICOAGULANTS
Anticoagulant medicines work
by interrupting part of the
process involved in the
formation of blood clots.
Blood clots are less likely to
form where they are not
needed, but can still form
when they are needed
Deep Vein
Trombosis
Pulmonary
Embolism
Risk of a
stroke
Atrial
Fibrillation
Risk of
developing
Blood Clots
After
Surgery
What are anticoagulants used for?
YEARLY EXPENSES
In 2008, 6,2 billion US Dollars
were spent on anticoagulants
In 2014, 9,1 billion US Dollars
were spent on anticoagulants
LMWH
DTI
Heparin
Factor Xa
inhibitors
Warfarin
Other
LMWH
DTI
Heparin
Factor Xa
inhibitors
Warfarin
OtherSource:
http://www.nature.com/nrd/journa
l/v8/n5/fig_tab/nrd2851_ft.html
Warfarin has shown to
reduce the risk of AF-
related strokes by 64%
as opposed to 19% by
Antiplatelets such as
Aspirin
Due to serious side-effects,
medicine optimisation is
necessary
The NOACs: Apixaban,
Dabigatronetexilate & Rivaroxaban
are the first major innovation in the
prevention of non valvular Atrial
Fibration stroke in 50 years
http://www.abpi.org.uk/our-work/library/medical-disease/Documents/ABPI%20SAFI%20report.pdf
Preventive stroke care will save
governments enormous amounts of
money
Continuous optimisation
safer medicines
Talentum BioTech offers
customized molecular simulation and
bioactive compound discovery services
to biopharma companies & academic
research groups
Talentum BioTech has experience
in the field of Anticoagulants
Click on logo to directly visit our website
(http://www.talentum-biotech.com/en/)

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Anticoagulants: research in development

  • 2. Anticoagulant medicines work by interrupting part of the process involved in the formation of blood clots. Blood clots are less likely to form where they are not needed, but can still form when they are needed
  • 3. Deep Vein Trombosis Pulmonary Embolism Risk of a stroke Atrial Fibrillation Risk of developing Blood Clots After Surgery What are anticoagulants used for?
  • 4. YEARLY EXPENSES In 2008, 6,2 billion US Dollars were spent on anticoagulants In 2014, 9,1 billion US Dollars were spent on anticoagulants LMWH DTI Heparin Factor Xa inhibitors Warfarin Other LMWH DTI Heparin Factor Xa inhibitors Warfarin OtherSource: http://www.nature.com/nrd/journa l/v8/n5/fig_tab/nrd2851_ft.html
  • 5. Warfarin has shown to reduce the risk of AF- related strokes by 64% as opposed to 19% by Antiplatelets such as Aspirin
  • 6. Due to serious side-effects, medicine optimisation is necessary The NOACs: Apixaban, Dabigatronetexilate & Rivaroxaban are the first major innovation in the prevention of non valvular Atrial Fibration stroke in 50 years http://www.abpi.org.uk/our-work/library/medical-disease/Documents/ABPI%20SAFI%20report.pdf
  • 7. Preventive stroke care will save governments enormous amounts of money Continuous optimisation safer medicines
  • 8. Talentum BioTech offers customized molecular simulation and bioactive compound discovery services to biopharma companies & academic research groups Talentum BioTech has experience in the field of Anticoagulants Click on logo to directly visit our website (http://www.talentum-biotech.com/en/)