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Clinical &
                            Translational
                                                                           CTSI-CRS Sample Processing Core Laboratories
                            Sciences                                                                            Wendy Staub, Lab Manager
                            Institute                                                                        wendy.staub@ucsf.edu 415-794-6460
                                                                                                                                                                                                UCSF
                                                                                                                                                              CTSI Clinical Research Services
The CTSI-CRS Sample
                                                                                Moffitt         Moffitt       Mt. Zion   San Francisco   Tenderloin
Processing Core                                                              Hospital Adult    Hospital       Hospital     General        Research
                                                                                              Pediatrics &                 Hospital        Center
Laboratories perform                                                                             NCRC
                                                    Specimen aliquoting                                                                 
specimen processing,
sample storage, and                                 Serum/plasma                                                                        
                                                    separation
shipping for more than                              Buffy coat isolation                                                                
                                                    Addition of protease                                                                
200 clinical studies.                               inhibitors, etc.
                                                    Blood smear                                                                         
Our services are                                    preparations
                                                    Shipping                                                                            
available to all UCSF                               Short-term storage                                                     
faculty, residents, and                             (3 months max.)
                                                    PBMC isolation                               
research fellows.                                   EBV transformation                                                                                          Labeling, Set-up
                                                    of B cells
                                                    Cryopreservation of                          
                                                    cells
We have five                                        Cell staining for flow                       
                                                    cytometry                                                                                               Shipping           Processing
laboratories located at:                            Point-of-care testing                                                                   
                                                    (rapid HIV, rapid
• Moffitt Hospital, Adult                           HCV)

• Moffitt Hospital,                                        More than 45,000 samples processed in 2011                                                            Storage, Inventory
  Pediatrics
• Mt. Zion Hospital
• SFGH
• Tenderloin Research
  Clinic

Sample types:
• Blood
• Urine
• Saliva
• Amniotic Fluid
• Cerebrospinal Fluid                                                 Mt. Zion Lab                              Transfer pipettes




    This publication made possible by Grant
    Number UL1 RR024131 from the National
   Center for Research Resources (NCRR), a
component of the National Institutes of Health
(NIH), and NIH Roadmap for Medical Research.
Its contents are solely the responsibility of the
 authors and do not necessarily represent the
  official view of NCRR or NIH. Information on
  NCRR available at http://www.ncrr.nih.gov/.
   Information on Re-engineering the Clinical
   Research Enterprise can be obtained from
http://nihroadmap.nih.gov/clinicalresearch/ove
              rview-translational.asp                                 Moffitt Adult Lab                                         SFGH Lab              TCRC Lab                              PCRC staff

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How Does Sample Processing Work? Insights from a Core Lab at the University of California, San Francisco

  • 1. Clinical & Translational CTSI-CRS Sample Processing Core Laboratories Sciences Wendy Staub, Lab Manager Institute wendy.staub@ucsf.edu 415-794-6460 UCSF CTSI Clinical Research Services The CTSI-CRS Sample Moffitt Moffitt Mt. Zion San Francisco Tenderloin Processing Core Hospital Adult Hospital Hospital General Research Pediatrics & Hospital Center Laboratories perform NCRC Specimen aliquoting      specimen processing, sample storage, and Serum/plasma      separation shipping for more than Buffy coat isolation      Addition of protease      200 clinical studies. inhibitors, etc. Blood smear      Our services are preparations Shipping      available to all UCSF Short-term storage     faculty, residents, and (3 months max.) PBMC isolation   research fellows. EBV transformation   Labeling, Set-up of B cells Cryopreservation of   cells We have five Cell staining for flow   cytometry Shipping Processing laboratories located at: Point-of-care testing  (rapid HIV, rapid • Moffitt Hospital, Adult HCV) • Moffitt Hospital, More than 45,000 samples processed in 2011 Storage, Inventory Pediatrics • Mt. Zion Hospital • SFGH • Tenderloin Research Clinic Sample types: • Blood • Urine • Saliva • Amniotic Fluid • Cerebrospinal Fluid Mt. Zion Lab Transfer pipettes This publication made possible by Grant Number UL1 RR024131 from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH), and NIH Roadmap for Medical Research. Its contents are solely the responsibility of the authors and do not necessarily represent the official view of NCRR or NIH. Information on NCRR available at http://www.ncrr.nih.gov/. Information on Re-engineering the Clinical Research Enterprise can be obtained from http://nihroadmap.nih.gov/clinicalresearch/ove rview-translational.asp Moffitt Adult Lab SFGH Lab TCRC Lab PCRC staff