Presented at the UC Braid Retreat: Imagine a statewide research engine of pooled resources, data, and expertise that accelerates the “translation” of academic research to direct patient benefit. That's the goal of the University of California Biomedical Research Acceleration, Integration, and Development (UC BRAID) program.

1. UC-Research eXchange (UC-ReX): Connecting Data Across our Clinical Data Warehouses UC-Wide Biomedical Research Acceleration Initiative Retreat 9/23/11

5. Planned Evolution of Data Sharing Cross-institutional Cohort Discovery Extract Combined Limited Data Sets Quality Improvement Query tools Integration with Analytics Comparative Effectiveness / Clinical Trials De-identification Integration with IRB UC-ReX is funded for Cross-institutional work, each campus is responsible for their own Data Warehouse Development $5M over 5 years Y1 Accrual for CTs

6. Researcher wants AATD and COPD data Semantic Integration for Cohort Discovery Return data D Request for data D UCD (Epic) UC Irvine (Allscripts) UCLA (Epic) UCSF (Epic) UCSD (Epic) Querying Across Institutions Extraction Transformation Load (even with same vendor the EMRs are configured differently) UCD (DW) UC Irvine (DW) UCLA (DW) UCSF (DW) UCSD (DW)

7. Year 0 Proof-of-Concept of Cross-Institutional Cohort Discovery UC Davis Researcher UCSF UC System data sets UC Davis UC Irvine Reference Ontology Research Project Limited number of diseases Not 24/7 production system

8. Year 1 Real Cross-Institutional Cohort Discovery UC Davis Researcher UC System data sets Reference Ontology UC San Diego UC Irvine UCSF UC System data sets UC LA UCLA UC Davis UC Davis

10. Clinical Data at UC UC is investing > $500,000,000 to collect patient data through EMRs 1% of this to enable data sharing initiatives for research and quality improvement