The Challenges of Developing New Markets for a Start-Up - Technology, Trials, Standards and Ethics.

1. The challenges facing a medtech start-up in developing new markets – technology, standards, trials and reimbursement Michael Caulfield – CEO Intelesens Ltd

4. welcomes The world’s first intelligent, wearable, non-invasive, wireless device monitoring the patient’s vital signs remotely www.intelesens.com

6. Our focus is on improving the quality of care for aging and ill populations while delivering compelling cost advantages and benefits for healthcare providers Our value proposition

7. Our Products

8. Vitalsens V-Patch wireless monitor measuring 3-lead ecg, heart rate, and detecting cardiac arrhythmias regulatory approval 2009 regulatory approval 2011

9. Vitalsens V-Patch wireless monitor measuring 3-lead ecg, heart rate, and detecting cardiac arrhythmias

10. Vitalsens Aingeal in-hospital wi-fi monitor measuring ecg, heart rate, respiration rate, temperature and motion in an ambulatory patient regulatory approval 2011 regulatory approval 2010

11. The Competition

12. The Trials

13. Vitalsens March 2010 Trial 1

14. Aingeal General Purpose In-Hospital Monitor - July 2010 A clinical trial using the Aingeal monitor began in Massachusetts General Hospital in Boston in July 2010 The Aingeal device will be used in a surgical ward and will measure ecg, heart rate, respiration rate, temperature and motion. It communicates with patient records database via the hospital’s wi-fi network Trial 2

15. Trial 3 AMNCH Hospital Dublin V-Patch used to monitor cardiac patients at home http:// canberra.intelesens.com /Demo/

16. Technology Phase Trials and Testing Phase Adoption, Reimbursement and Procurement Phase Marketing and Sales Phase Ulster MGH Tallaght

18. In-hospital, wireless vital signs monitor At-home, wireless vital signs monitor temp resp pulse ox ecg motion Delays and avoids ward admissions Expedites hospital discharge ecg SpO 2 temp resp motion