How dangerous is this really?

1. (Understand &) Explain Pain Lorimer Moseley NHMRC Senior Research Fellow Prince of Wales Medical Research Institute, Sydney, Australia Senior Fellow The GAMFI project University of Oxford, UK © GL Moseley www.BodyInMind.com.au

7. Complex reasoning p ain mechanisms based on experience, context, environment…MEANING © GL Moseley www.BodyInMind.com.au

8. Complex reasoning mechanisms based on experience, context, environment…MEANING “How dangerous is this really?” © GL Moseley www.BodyInMind.com.au

9. Pain does not provide an accurate indication of tissue state – It makes us take action to promote our well-being (get out of danger!) © GL Moseley www.BodyInMind.com.au

10. Every represented byte can modulate Pain ‘Basic’ protective responses Motor system Immune system Autonomic system © GL Moseley www.BodyInMind.com.au

11. Every represented byte can modulate Pain ‘Basic’ protective responses Motor system Immune system Autonomic system © GL Moseley www.BodyInMind.com.au

12. Every represented byte can modulate Pain ‘Basic’ protective responses Motor system Immune system Autonomic system © GL Moseley www.BodyInMind.com.au

13. Every represented byte can modulate Pain ‘Basic’ protective responses Motor system Immune system Autonomic system © GL Moseley www.BodyInMind.com.au

14. Every represented byte can modulate Pain ‘Basic’ protective responses Motor system Immune system Autonomic system © GL Moseley www.BodyInMind.com.au

16. Every represented byte can modulate Sum evaluative inputs = “It is not as dangerous as that” Pain ‘Basic’ protective responses Motor system Immune system Autonomic system © GL Moseley www.BodyInMind.com.au

17. Every represented byte can modulate Sum evaluative inputs = “It is not as dangerous as that” Pain ‘Basic’ protective responses Motor system Immune system Autonomic system © GL Moseley Descending inhibition www.BodyInMind.com.au

18. Every represented byte can modulate Sum evaluative inputs = “It is not as dangerous as that” Pain ‘Basic’ protective responses Motor system Immune system Autonomic system © GL Moseley Descending inhibition www.BodyInMind.com.au

19. Every represented byte can modulate Sum evaluative inputs = “It is not as dangerous as that” Pain ‘Basic’ protective responses Motor system Immune system Autonomic system © GL Moseley Descending inhibition www.BodyInMind.com.au

20. Every represented byte can modulate Sum evaluative inputs = “It is more dangerous that that” Pain ‘Basic’ protective responses Motor system Immune system Autonomic system © GL Moseley www.BodyInMind.com.au

21. Every represented byte can modulate Sum evaluative inputs = “It is more dangerous that that” Pain ‘Basic’ protective responses Motor system Immune system Autonomic system © GL Moseley Descending facilitation www.BodyInMind.com.au

22. Every represented byte can modulate Sum evaluative inputs = “It is more dangerous that that” Pain ‘Basic’ protective responses Motor system Immune system Autonomic system © GL Moseley Descending facilitation www.BodyInMind.com.au

23. Every represented byte can modulate Sum evaluative inputs = “It is more dangerous that that” Pain ‘Basic’ protective responses Motor system Immune system Autonomic system © GL Moseley Descending facilitation www.BodyInMind.com.au

24. Thanks Lorimer Moseley NHMRC Senior Research Fellow Prince of Wales Medical Research Institute, Sydney, Australia Senior Fellow The GAMFI project University of Oxford, UK © GL Moseley www.BodyInMind.com.au