This document discusses different types of stones that can form in the urinary tract, including calcium oxalate, phosphate, uric acid, and struvite stones. It also discusses conditions that can mimic stones on imaging, such as nephrocalcinosis, phleboliths, pancreatic and adrenal calcification, dermoid cysts, gallstones, and vascular and renal calcification. Stones can cause obstruction of the urinary tract and lead to hydronephrosis. Specific stone locations like ureteric, bladder, and jack stones are also covered.
3. Calcium Oxalate Stones
80% of kidney stones contain
calcium
General appearance:
1. White, hard, radiopaque
2. Calcium PO4: staghorn in renal
pelvis (large)
3. Calcium oxalate: present in
ureter (small)
4. Called Mulberry stone (brown)
with sharp projections.
4. Phosphate Stones
10-15%
Either be Calcium phosphate
(magnesium or ammonium)
Occurs in infection
Smooth and white color
In alkaline urine, it enlarges
rapidly, filling renal calyces
and taking their shape
(STAGHORN CALCULUS).
Radiopaque
5. Uric Acid Stones
8% of renal stones contain uric
acid
associated with hyperuricemia
(with or without gout)
General appearance:
1. Small, friable, yellowish
2. May form staghorn
3. Radiolucent (plain x-rays
cannot detect)
6. Struvite Stones
Compound of magnesium,
ammonium phosphate mixed
with carbonate.
associated with chronic UTI
Occurs in presence of
ammonia and urea splitting
organisms in urine (e.g.
Proteus, Klebsiella)
Radiopaque
7. Staghorn Calculus
Stone occupying the renal
pelvis and calyces
Triple phosphate stone
White in color, soft, smooth
occurs in pre-existing
infection.
Unilateral/Bilateral
8. Caliceal calculi that are non-obstructing are usually
asymptomatic.
Patients with small caliceal calculi may still have gross or
microscopic hematuria and may have colic symptoms despite
the lack of imaging findings suggestive of obstruction.
9. Calculi causing Hydronephrosis
Hydronephrosis is dilatation of the renal pelvis and calyces.
It can be caused by obstruction of the ureters or bladder outlet. Hydronephrosis can also
result from reflux (retrograde leakage of urine from the bladder up the ureters to the
renal pelvis.
10. Ureteric Calculus
1. Always of Renal Origin
2. Commonly of elongated shape
3. Can get impacted at 3 constrictions of
ureter
4. Can cause:
Obstruction
Hydronephrosis
Infection
Ureteral Stricture
5. C/F:
Colicky Pain (from loin to tip genitalia)
along genitofemoral nerve.
Hematuria, dysuria, frequency,
strangury
Tenderness in iliac fossa
11.
12.
13. Bladder Calculus
1. Primary vesical calculus:
• occurs in sterile urine
• Comes down from kidney through ureter
and gets enlarged in bladder (usually
oxalate stone).
• Can irritate bladder mucosa causing
hematuria
2. Secondary vesical calculus:
• Occurs in presence of infection
(commonest bladder stone)
• Usually phosphate stone, occurs in
bladder only
14. Etiology
Same as that of Renal
Calculus
Others:
1. Diverticula bladder: which
lead to stagnation of urine
superadded infection stone
formation
2. BPH
3. Urethral Stricture
4. Neurogenic Bladder
5. Schistosomiasis
15. Bladder stones generally form in
the bladder itself.
Causes:
1. bladder outflow obstruction
(enlarged prostate)
2. neurogenic bladder (loss of
bladder function due to spinal
cord injury/disease).
3. Those with bladder wall
abnormalities (ureterocele,
diverticulum) or
4. those with recurrent urinary
infections are also at higher risk
of forming bladder stones.
When seen on an
abdominal/pelvic X-ray they are
often multiple and rounded.
16. Bladder Stone
Note that this stone has a
faint longitudinal lucency
which is the nidus around
which the stone developed.
17. Jack Stone
Jackstone calculi resembles toy
jacks.
composed of calcium oxalate
dehydrate
dense central core and radiating
spicules.
light brown with dark patches
and are usually described to
occur in the urinary bladder and
rarely in the upper urinary tract.
20. Nephrocalcinosis
Refers to renal parenchymal
calcification. The calcification may be
dystrophic or metastatic.
1. With dystrophic calcification, there is
deposition of calcium in necrotic
tissue.
This type of parenchymal calcification
occurs in tumors, abscesses, and
hematomas.
2. Metastatic nephrocalcinosis occurs
most often with hypercalcemic states
caused by hyperparathyroidism, renal
tubular acidosis, and renal failure.
Metastatic nephrocalcinosis can be
further categorized by the location of
calcium deposition as cortical or
medullary.
21. Causes of Nephrocalcinosis
Causes of cortical nephrocalcinosis include
1. acute cortical necrosis
2. chronic glomerulonephritis
3. chronic hypercalcemic states
ethylene glycol poisoning, sickle cell disease, and
rejected renal transplants
Causes of medullary nephrocalcinosis include
1. hyperparathyroidism (40%)
2. renal tubular acidosis (20%)
3. medullary sponge kidney
bone metastases, chronic pyelonephritis, cushing’s
syndrome,
hyperthyroidism, malignancy, renal papillary
necrosis,sarcoidosis, sickle cell disease, vitamin D
excess, and Wilson’s disease.
22. Phleboliths
Calcification within venous
structures.
Common in the pelvis where they
may mimic ureteric calculi, and
are also encountered frequently in
venous malformations.
Round in shape (but not always)
of a similar size that would
correspond to the diameter of
pelvic veins
1. look like a ring of bone
2. tend to occur laterally around the
urinary bladder
3. appear as focal calcifications,
often with radiolucent centers
23. Pancreatic calcification
retroperitoneal organs such as
the pancreas which only
become visible when calcified.
Pancreatic calcification is a
feature of chronic pancreatitis.
24. Adrenal Calcification
Adrenal (suprarenal)
calcification is an uncommon
finding and is usually
incidental. Most often it is
considered a result of
previous haemorrhage or
tuberculosis.
26. Gallstones (10% radiopaque)
Radiopaque lucency in the RUQ
and presents with typical
laminated appearance
Note anterior location on lateral
projection
27. Gallstones have a variable
position depending on the
position of the gallbladder and
may be mistaken for renal
stones
Unlike renal stones they are
often rounded and cluster
together
29. Vascular Calcification
Calcification of arteries seen
on x-rays is a sign of more
generalised atherosclerosis.
Occasionally vascular
calcification seen on an
abdominal X-ray reveals an
unexpected aneurysm
30. Typical appearance of
calcified abdominal aorta
Note the outward bulging of
the anterior wall
31. Renal Tuberculosis
Genitourinary tract
tuberculosis. Lobar
calcification in a large
destroyed right kidney in a
patient with renal
tuberculosis. Note the
involvement of the right ureter
35. The calcified lesions at the bottom
of the image are scrotal calculi
which are also known as a fibrinoid
loose bodies or scrotal pearl.
Scrotoliths or scrotal pearls
are benign incidental extra
testicular macro-calcifcations within
the scrotum. They frequently occupy
the potential space of the tunica
vaginalis or sinus of the
epidydimis. They are usually of no
clinical significance.
Causes
micro trauma / repetitive trauma to
scrotal region - e.g. mountain bikers
prior torsion appendix of testis
Scrotoliths/Scrotal Pearls
Drug-induced stone disease
precipitate in urine causing stone formation. Include indinavir; atazanavir; triamterene; silicate (overuse of antacids containing magnesium silicate); and sulfa drugs.
Bilateral can cause renal failure (edema feet, oligouria)
Scan shows mild dilatation of the pelvis as well as the calyces of the right kidney suggesting mild hydronephrosis. The left kidney also appears to be affected similarly. This must be differentiated from mild dilatation of the renal pelvis alone, which is physiological and transient; this means that on emptying of the urinary bladder, this appearance should disappear.
Multiple lower-pole and renal pelvic echoreflective calculi showing acoustic shadowing are associated mild hydronephrosis.
Lower one 1/3rd of ureter
Sonography of the abdomen showed hydronephrosis of the right kidney with a moderately large calculus (14mm.) at the right Pelvi-ureteric junction (arrows). Such calculi cause partial obstruction of the renal pelvis and may cause severe ureteric colic.
2nd image shows multiple, small calculi (3 to 4 mm. in size) in both ureters.
Diverticula bladder - out pouching of bladder. Focal herniations of the urothelium and submucosa and usually occur in the setting of chronic elevation of intravesical pressure.
Pelvic ultrasound shows a large out pouching (D) of the bladder wall and mucosa projecting from the lumen of the bladder (B).
Penile – Bulbar – Membranous – Prostatic Urethra
Neurogenic bladder is often associated with spinal cord diseases (Syringomyelia), injuries, and neural tube defects including spina bifida. It may also be caused by brain tumors, and by peripheral nerve diseases.
In urinary schistosomiasis the eggs in the bladder may become focuses of stone formation; fibrosis may extend to the pelvic organs, and there may be secondary bacterial infection of the urinary tract.
densely radio-opaque, calculi may be single or multiple and often large. Frequently lamination is observed internally, like the skin of an onion.
An irregular, echogenic, shadowing structure is seen within the bladder. The appearance of the structure resembles a toy jack - hence the designation jackstone.
Medullary sponge kidney where the sharp areas of calcification and uneven distribution may be seen
The renal parenchyma contains clusters of small calcific densities.
B, Sagittal sonogram
shows extensive medullary calcification in a patient with renal tubular acidosis.
The larger calcified arrowed structure is almost definitely a phlebolith which is a calcific ring in the wall of a pelvic vein.
The smaller calcific structure is also probably a phlebolith but has some of the features of a renal stone in terms of its position and shape.
This X-ray shows soft tissue calcification which follows the anatomical position of the pancreas and crosses the midline.
Also note calcification of the abdominal aorta which is of normal calibre
The adrenal (suprarenal) glands form a triangle shape lying directly above the kidneys.
RADIOGRAPH KUBA faint radiopacity is seen overlying right renal shadow.Two arc like calcifications are seen in the pelvis on both sides.Sub-optimal bowel preparation .Pro-peritoneal fat lines are maintained.Visualized renal shadows is normal.Visualized psoas shadows are normal.Visualized bones and joints are normal.IMPRESSION:
? Right renal / GB calculus
Two tubo-ovarian stromal fibroid calcifications.
Mature cystic teratomas are encapsulated tumours with mature tissue or organ components. They are composed of well-differentiated derivations from three germ cell layers (ectoderm, mesoderm, and endoderm).
Ectoderm – hair, teeth, nails
This X-ray also shows an incidental calcified mesenteric node which may also mimic renal stones
an appendicolith (uncommon feature of appendicitis) is highly predictive of the diagnosis in patients presenting with abdominal pain, and is also thought to be associated with a higher risk of gangrene or perforation.
There is striking calcification of the aorta and iliac vessels. This is a sign of generalised atherosclerosis elsewhere in the body.
There is calcification of the dilated aortic wall. As in this case often only one side of the aneurysm is visible - the other projected over the spine.