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                                    Aphasiology
                                    Publication details, including instructions for authors and subscription information:
                                    http://www.informaworld.com/smpp/title~content=t713393920
                                    Aphasia Therapy or The importance of being earnest
                                    Anna Basso a; Alessandra Caporali a
                                    a
                                      Milan University, Italy.

                                    Online Publication Date: 01 April 2001
                                    To cite this Article: Basso, Anna and Caporali, Alessandra (2001) 'Aphasia Therapy
                                    or The importance of being earnest', Aphasiology, 15:4, 307 - 332
                                    To link to this article: DOI: 10.1080/02687040042000304
                                    URL: http://dx.doi.org/10.1080/02687040042000304



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APHASIOLOGY, 2001, 15 (4), 307–332
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                                                                                                                              Aphasia Therapy
                                                                                                                                     or
                                                                                                                        The importance of being earnest
                                                                                                                          Anna Basso and Alessandra Caporali
                                                                                                                                       Milan University, Italy


                                                                                                   Effectiveness of aphasia therapy, at least for some patients, is no longer under discussion but
                                                                                                   the specific effect of most of the variables influencing recovery is unknown. In this paper we
                                                                                                   address a question relative to the therapeutic regimen. Three pairs of patients with similar
                                                                                                   age, educational level, sex, aetiology, lesion site, and type and severity of aphasia are
                                                                                                   compared. Except for one of the control patients who was 2 months post-onset, all patients
                                                                                                   were at least 6 months post-onset (range: 6–22 months) and had already been rehabilitated
                                                                                                   when they entered the study. The three experimental subjects underwent a very long and
                                                                                                   intensive therapeutic programme (2/3 hours per day, 7 days per week, for many months),
                                                                                                   with the help of the family and volunteers. The control patients were rehabilitated daily (1
                                                                                                   hour, 5 days a week) for similar periods of time. It is argued that the intensive treatment
                                                                                                   achieved higher test scores and more prolonged recovery and that the experimental patients
                                                                                                   made better use of their recovered language in daily life.


                                                                                                                                         INTRODUCTION
                                                                                                It is now generally agreed that aphasia therapy can be effective, namely that an aphasic
                                                                                                patient will have better chances of recovery if he or she is rehabilitated. Experimental
                                                                                                evidence comes from group studies (Basso, Capitani, & Vignolo, 1979; Basso, Faglioni,
                                                                                                & Vignolo, 1975; Gloning, Trappl, Heiss, & Quatember, 1976; Hagen, 1973; Mazzoni et
                                                                                                al, 1995; Poeck, Huber, & Willmes, 1989) and single case studies (Byng, 1988; De Partz,
                                                                                                1986; Jones, 1986). The beneficial effect of therapy is also confirmed by results of meta-
                                                                                                analyses (Robey, 1994, 1998). In his 1998 study, Robey reviewed 55 reports on the
                                                                                                effectiveness of aphasia therapy and studied whether there is a difference between treated
                                                                                                and untreated patients. The reanalysis of the data showed a distinction between treated
                                                                                                and untreated patients, which exceeded the criterion value for a medium-sized effect.
                                                                                                However, the question is far from being settled because we still need to know which
                                                                                                patients (or, perhaps better, which impairments) can be profitably rehabilitated and how.
                                                                                                In a few single case studies both the impairment and the intervention have been described
                                                                                                in a sufficiently detailed way so as to be reproducible (Byng, 1988; De Partz, 1986;
                                                                                                Jones, 1986; Miceli, Amitrano, Capasso, & Caramazza, 1996). However, we do not know
                                                                                                whether other variables (such as the associated disorders or the therapeutic regimen) have
                                                                                                an effect on recovery and therefore we cannot be sure whether another patient showing


                                                                                                   Address correspondenc e to: Anna Basso, Neurological Clinic, Via F. Sforza 35, 20122 Milan, Italy. Email:
                                                                                                abasso@micronet.it

                                                                                                                                       # 2001 Psychology Press Ltd
                                                                                                http://www.tandf.co.uk/journals/pp/02687038.html                          DOI:10.1080/02687040042000304
308     BASSO AND CAPORALI


                                                                                                the same functional impairment (but different in other respects) would benefit from the
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                                                                                                same intervention.
                                                                                                    A theory of rehabilitation should comprise various aspects, the most important being
                                                                                                the intervention strategies themselves. Other important aspects are the characteristics of
                                                                                                the patient (such as age and education), the functional damage (impaired word
                                                                                                comprehension, impaired lexical reading, and so on), and the therapeutic regimen.
                                                                                                    In this paper we shall address a question relative to the therapeutic regimen. In the
                                                                                                literature there are some descriptions of patients who have benefited from very brief
                                                                                                periods of therapeutic interventions (see, for instance, Byng, 1988; Marshall, Pound,
                                                                                                White-Thompson, & Pring, 1990; Penn, 1993). In the majority of cases these are chronic
                                                                                                patients who can be used as their own controls. After having received what is generally
                                                                                                called traditional therapy and having reached a plateau, they are offered a new method
                                                                                                and show recovery of the treated impairment. TC (Penn, 1993), for instance, was a
                                                                                                multilingual aphasic patient 9 months post-onset who ‘‘had a mild aphasia with relatively
                                                                                                intact receptive abilities, fluent output, and marked word-finding difficulty’’ (p. 36) when
                                                                                                a discourse-based therapy programme was implemented. The programme was carried out
                                                                                                in nine sessions after which ‘‘improvement in the target areas was noted in all languages
                                                                                                despite the fact that therapy was conducted only in English; the specific targeted
                                                                                                behaviors (. . .) were assessed as being markedly more appropriate across the tested
                                                                                                languages’’ (Penn, 1993, p. 40). BRB (Byng, 1988), a frequently cited case, was 6 years
                                                                                                post-onset (during which time he had been rehabilitated) when he received a specific
                                                                                                programme for mapping thematic roles onto grammatical relations. Therapy consisted of
                                                                                                two sessions a week apart and intervening homework. BRB showed marked improvement
                                                                                                in his comprehension of locative sentences (which had been the object of therapy) and of
                                                                                                simple reversible sentences, as well as in sentence production, which had not been
                                                                                                rehabilitated.
                                                                                                    Unfortunately this has never been our experience. We have seen patients recover with
                                                                                                therapy, but following intensive treatment. Over the years we have been augmenting what
                                                                                                we considered the minimum duration and intensity of aphasia rehabilitation necessary for
                                                                                                recovery to show up in daily life, also in view of the fact that there is some experimental
                                                                                                evidence that to be effective rehabilitation must be intensive and protracted (see Basso,
                                                                                                1992 for a review).
                                                                                                    The regimen we now offer to our patients generally consists of 1-hour daily sessions,
                                                                                                supported by intensive homework (2–3 hours per day) and protracted for many months
                                                                                                with control examinations every 3 months. The rationale for discontinuing the therapy is
                                                                                                no recovery between two successive control examinations.
                                                                                                    This regimen in not easy to implement. We must first persuade the patient and his or
                                                                                                her family that this is necessary and then help them to find a way to implement the
                                                                                                necessary homework. With the help of the family, we try to identify a relative, a friend, or
                                                                                                a volunteer who can do it. We must also identify the objectives of the rehabilitation
                                                                                                programme that can be pursued by a lay person and the exercises that can be carried out
                                                                                                by the patient alone.
                                                                                                    The focus of this paper is the regimen of aphasia therapy. The paper does not raise the
                                                                                                issue of the content of therapy nor does it discuss our approach, which is described in
                                                                                                some detail elsewhere (Basso, 1977, 1999). Briefly, we can say that in our aphasia unit
                                                                                                we adopt two rather different approaches. In those cases in which we can arrive at a
                                                                                                precise functional diagnosis with reference to a cognitive neuropsychologica l model of
                                                                                                normal processing, we endeavour to target the identified impairment/s and implement
                                                                                                what could be broadly defined as a cognitive neuropsychologica l approach. For severely
APHASIA THERAPY         309

                                                                                                damaged patients with an across-the-board impairment, less analytic approaches targeting
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                                                                                                the disability itself can prove efficacious. By way of example, if a patient has an
                                                                                                understanding disorder that can be explained by, say, damage to the input lexicon, it
                                                                                                appears obvious to target the damaged lexicon. If, however, comprehension is severely
                                                                                                impaired and the patient fails all tasks, a cognitive diagnosis is still possible but it is not
                                                                                                really helpful in dictating what to do. We prefer to rehabilitate comprehension as a global
                                                                                                behaviour in more ecological settings such as a conversation. The principal function of
                                                                                                language is to permit communication among human beings and the main goal of
                                                                                                rehabilitation is to enable the patient to communicate through language. To communicate
                                                                                                the patient must be able to understand what his or her interlocutor is saying and to express
                                                                                                what he or she wants to say. In this sort of therapy, the therapist engages the patient in a
                                                                                                conversation which must be as similar as possible to a natural conversation the patient
                                                                                                may want to sustain in his or her daily life. Right from the beginning of the treatment the
                                                                                                patient’s participation must be similar to normal conversational behaviour. For each
                                                                                                patient we also identify specific goals (reduction of apraxia of speech, prevention of
                                                                                                agrammatism, recovery of word-finding abilities, reading aloud, and so on) with the aim
                                                                                                of setting the stage for a successive and more specific intervention. If we want to label
                                                                                                our intervention strategies, it can perhaps be suggested that for severe aphasic patients
                                                                                                our intervention can be considered loosely akin to the so-called stimulation approach (see
                                                                                                Howard & Hatfield, 1987, for a review).
                                                                                                   In this paper we attempt to demonstrate that an intensive therapeutic regimen can
                                                                                                cause such a degree of recovery as to show up in the patient’s daily living. We are not
                                                                                                investigating the outcome of therapy for a well-defined task such as, for instance, naming
                                                                                                of 50 action pictures or reading of nonwords. We compare three pairs of patients matched
                                                                                                as far as possible for the variables known to influence recovery. They have all been re-
                                                                                                educated for long periods of time, the main difference being the intensity of the
                                                                                                rehabilitation: the three control patients were seen by the speech therapist for 1 hour 5
                                                                                                days per week, the three experimental patients were seen for 5 hours per week and were
                                                                                                also helped at home 2–3 hours per day.


                                                                                                                          PAIR 1: PATIENTS FC AND AM
                                                                                                Patient FC
                                                                                                FC was a 37-year-old right-handed mechanic with 13 years of education who suffered a
                                                                                                CVA in June 1997; his previous medical history was uneventful. He was admitted
                                                                                                unconscious to hospital where a CT-scan showed ischaemic damage to the left frontal-
                                                                                                temporal-parietal area surrounde d by oedema. Neurological assessment immediately
                                                                                                post-stroke indicated global aphasia and right hemiplegia. The patient recovered clear
                                                                                                consciousness in the following days and underwent motor rehabilitation. A MRI
                                                                                                performed in April 1999 showed a large temporal-parietal lesion with extensive
                                                                                                involvement of the white matter and the subcortical structures.
                                                                                                   When discharged from the hospital in August, FC was admitted to a rehabilitation
                                                                                                clinic where he started language rehabilitation, 5 days a week, until November when he
                                                                                                went home. He continued language rehabilitation in the same clinic on an outpatient basis
                                                                                                four times per week during the first months, which reduced to three and then two times a
                                                                                                week. He had been dismissed from rehabilitation when first seen at the Aphasia Unit of
                                                                                                Milan University in February 1999, 20 months post-stroke, after being told that no further
                                                                                                recovery was possible.
310     BASSO AND CAPORALI


                                                                                                   The language examination (Ciurli, Marangolo, & Basso, 1996) at this time
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                                                                                                demonstrated that it was not possible to classify FC’s language impairments into any
                                                                                                of the classical syndromes, and a diagnosis of mixed nonfluent aphasia (Goodglass &
                                                                                                Kaplan, 1983) was considered appropriate. He also showed verbal apraxia and acalculia
                                                                                                (on a written calculation test he scored 15/101; cut-off score: 74/101; Basso & Capitani,
                                                                                                1979). He had no oral apraxia (20/20; cut-off score: 17/20; De Renzi, Pieczuro, &
                                                                                                Vignolo, 1966) or ideomotor apraxia (67/72; cut-off score: 53/72; De Renzi, Motti, &
                                                                                                Nichelli, 1980). His speech was impoverished and scanty; few isolated words (generally
                                                                                                nouns) were produced with long pauses. Naming of object pictures was 60% correct,
                                                                                                naming of action pictures was 30% correct. FC did not try to express himself using
                                                                                                gestures or any other nonverbal means; he rarely looked at the interlocutor and appeared
                                                                                                to be concentrating on trying to find the words to make himself understood. When his
                                                                                                attention was caught, comprehension was sufficient for simple questions but severely
                                                                                                impaired on the Token Test (13/36; cut-off score: 29/36; De Renzi & Faglioni, 1978).
                                                                                                Reading comprehension was at the same level as auditory comprehension. Reading aloud
                                                                                                and repetition were possible for single words but not for sentences; writing was
                                                                                                impossible except for copying which was generally correct. He scored 34/36 on the
                                                                                                Raven’s Coloured Progressive Matrices (Figure 1). The Appendix reports his description
                                                                                                of the picture of a drawing room where a woman is knitting, a man is reading a
                                                                                                newspaper, a girl is watching television, a boy is playing with blocks and a cat with a ball
                                                                                                of wool.
                                                                                                   FC had come to see us because he did not want to give up therapy. Mainly in
                                                                                                consideration of his young age, we thought this worthwhile notwithstanding two
                                                                                                important negative factors: the time elapsed since onset and the fact that the patient had
                                                                                                already been re-educated for 18 months. We discussed with FC and his wife the fact that
                                                                                                in our opinion his only chance of recovery depended on very hard and lasting work he
                                                                                                would have to do by himself, with a friend or a relative under our supervision, and
                                                                                                directly with us. Even in this case chances of recovery were rather poor because the
                                                                                                period of spontaneous recovery had finished long ago and he had already been re-
                                                                                                educated for a long period of time, although lately rehabilitation had been reduced. FC
                                                                                                and his wife agreed to do all they could. Because his wife worked and was away all day,
                                                                                                she could dedicate only an hour per day, in the evening, to her husband, with more time at
                                                                                                weekends. They found a young woman to work at home with him two more hours per day
                                                                                                and he received treatment at the Aphasia Unit for an hour daily. Initially his homework
                                                                                                consisted of sentence repetition and written action naming, tasks that a lay person can
                                                                                                easily handle. FC’s wife and assistant were shown how to work with the patient and they
                                                                                                regularly came to the clinic for supervision. Repetition was chosen because it could help
                                                                                                FC overcome his verbal apraxia (which was not very severe), give him confidence in his
                                                                                                capacity to produce sentences, and hopefully help prevent the production of agrammatic
                                                                                                sentences (Beyn & Shokhor-Trotskaya , 1966). Written naming was considered important
                                                                                                because of FC’s markedly reduced vocabulary, and actions instead of nouns were chosen
                                                                                                because he was inclined to use only nouns in speech and we thought that facilitating
                                                                                                retrieval of verbs could be helpful in preventing or reducing agrammatism.
                                                                                                   The therapist reserved for herself that which we thought was more difficult to
                                                                                                delegate. During the evaluation it had become clear that FC had severe difficulties in
                                                                                                having a conversation; he was eager to speak (frequently without succeeding in making
                                                                                                the interlocutor understand what he was talking about) but would not pay attention to
                                                                                                what was said to him. This made it very difficult to help him express himself by asking
                                                                                                adequate questions. It was then decided that the therapist would involve the patient in a
APHASIA THERAPY                311
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                                                                                                        February 1999 (Ciurli et al. 1996)                                                  TT = 13/36   Rv = 34/36

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                                                                                                              N      V      S      N         V   S      N     S    N     S     N      S     N      S      N     S
                                                                                                              Oral Production     Written Production      Oral      Written    Repetition   Reading      Writing to
                                                                                                                                                       Comprehen. Comprehen.                 aloud       dictation




                                                                                                        October 1999 (Ciurli et al. 1996)                                                   TT = 13/36   Rv = 36/36

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                                                                                                              Oral Production     Written Production      Oral      Written    Repetition   Reading      Writing to
                                                                                                                                                       Comprehen. Comprehen.                 aloud       dictation




                                                                                                           April 2000 (Ciurli et al. 1996)                                                  TT = 16/36   Rv = 50/60

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                                                                                                              N      V      S      N         V   S      N     S    N     S     N      S     N      S      N     S
                                                                                                              Oral Production     Written Production      Oral      Written    Repetition   Reading      Writing to
                                                                                                                                                       Comprehen. Comprehen.                 aloud       dictation



                                                                                                  TT = Token Test; RV = Raven’s Matrices; N = nouns; V = verbs; S = sentences.

                                                                                                Figure 1. Percentage correct responses by FC at three subsequent evaluations: February, 1999, October, 1999;
                                                                                                April, 2000.



                                                                                                conversation, rapidly changing the subject of the conversation and getting the patient
                                                                                                accustomed to answering in any possible way.
                                                                                                   A control evaluation 3 months later did not disclose much change, except for oral
                                                                                                action naming which was now 80% correct. We were not discouraged because we had not
                                                                                                expected much improvement in 3 months and therapy was continued.
                                                                                                   At home he was required to read aloud (which he could do by himself) and to decline
                                                                                                verbs he had first retrieved in the infinitive form. With the therapist he now started to read
312     BASSO AND CAPORALI


                                                                                                a short paragraph, imagine a scene that represented what he had read and, when he could
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                                                                                                clearly see the scene in his mind’s eye, describe it. This was thought to help him speak
                                                                                                because the content of the message was already clear in his mind; at the same time the
                                                                                                therapist did not know in advance what he was going to say and therefore it had a
                                                                                                communicative value.
                                                                                                   A second control examination in October 1999 (Ciurli et al., 1996) disclosed a
                                                                                                generalised although mild improvement in all language tasks. He was given a score of 5/
                                                                                                10 for his description of a picture (see Appendix) and he could write some words to
                                                                                                dictation and in a confrontation naming task. However, he still scored 13/36 on the Token
                                                                                                Test (Figure 1).
                                                                                                   Rehabilitation continued without any important change and a final control
                                                                                                examination was carried on in April 2000, after 14 months of intensive language
                                                                                                therapy (Ciurli et al., 1996). Improvement was now evident in all tasks and his speech
                                                                                                output was more abundant and more informative. Confrontation naming of nouns was
                                                                                                85% correct and of actions 70% correct, and he could write to confrontation 70% of
                                                                                                nouns and 60% of actions. It was now possible for him to read and repeat short sentences.
                                                                                                Only his score on the Token Test was not much changed (16/36) (Figure 1). His
                                                                                                comprehension in a conversation, however, was quick and correct. His production was
                                                                                                more abundant and informative although still agrammatic with some correct sentences,
                                                                                                and he did not wait to be asked something but frequently introduced new topics. The
                                                                                                appendix reports his retelling of a typical day.


                                                                                                Patient AM
                                                                                                AM was a 37-year-old right-handed bookbinder with 8 years of formal education who
                                                                                                suffered a CVA in July 1988. On admission to the hospital the neurological examination
                                                                                                showed mild right hemiparesis and expressive aphasia. A CT scan performed in October
                                                                                                1988 disclosed a large left temporal-parietal lesion with deep extension to the basal
                                                                                                ganglia. AM started daily language rehabilitation in September, which was still going on
                                                                                                in June 1989, 11 months post-onset, when he was first examined at the Aphasia Unit.
                                                                                                    The language examination (Basso & Vignolo, 1974) disclosed a mixed nonfluent
                                                                                                aphasia with severely reduced speech and verbal apraxia. His description of how to shave
                                                                                                is reported in the Appendix. Repetition and reading aloud were only mildly impaired for
                                                                                                words and nonwords but he could not repeat or read sentences. Writing was more
                                                                                                severely impaired than oral speech; he could sign and copy and he correctly wrote only
                                                                                                one of 20 words. Comprehension was adequate for oral and written words and sentences;
                                                                                                on the Token Test he scored 15/36. He had no oral (17/20) or ideomotor (69/72) apraxia
                                                                                                and scored 30/36 on the Raven’s Coloured Progressive Matrices. In the written
                                                                                                calculation test he scored 12/101 (Figure 2).
                                                                                                    Rehabilitation in our unit was started, an hour daily, with the immediate objectives of
                                                                                                reducing AM’s verbal apraxia by having him repeat short sentences. It was also thought
                                                                                                that this could prevent or reduce agrammatism. In order to augment his speech output and
                                                                                                his vocabulary he was engaged in conversations above various subjects and asked to
                                                                                                describe pictures.
                                                                                                    A control examination 6 months later, in December 1989 (Basso & Vignolo, 1974),
                                                                                                showed some recovery of speech production, which was now agrammatic but slightly
                                                                                                more fluent (see Appendix), and in writing of single words. His comprehension as
                                                                                                evaluated by the Token Test was much better (22/36). He scored 30/36 on the Raven’s
                                                                                                Coloured Progressive Matrices and 8/101 in the written calculation test (Figure 2). Daily
APHASIA THERAPY                    313
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                                                                                                      June 1989 (Basso & Vignolo, 1974)                                                 TT = 15/36 Rv = 30/36

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                                                                                                       0
                                                                                                            N      V      S    N      V      S      N     S    N     S     N      S     N       S       N      S
                                                                                                                 (n.t.)             (n.t.)

                                                                                                            Oral Production   Written Production      Oral      Written    Repetition   Reading         Writing to
                                                                                                                                                   Comprehen. Comprehen.                 aloud          dictation




                                                                                                    December 1989 (Basso & Vignolo, 1974)                                                   TT = 22/36 Rv = 30/36

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                                                                                                                 (n.t.)             (n.t.)

                                                                                                            Oral Production   Written Production      Oral      Written    Repetition   Reading         Writing to
                                                                                                                                                   Comprehen. Comprehen.                 aloud          dictation




                                                                                                      June 1990 (Basso & Vignolo, 1974)                                                     TT =18/36    Rv = 33/36

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                                                                                                                 (n.t.)             (n.t.)

                                                                                                            Oral Production   Written Production      Oral      Written    Repetition   Reading         Writing to
                                                                                                                                                   Comprehen. Comprehen.                 aloud          dictation



                                                                                                   TT = Token Test; RV = Raven’s Matrices; N = nouns; V = verbs; S = sentences; n.t. = not tested.

                                                                                                Figure 2. Percentage correct responses by AM at three subsequen t evaluations: June, 1989; December, 1989;
                                                                                                June, 1990.



                                                                                                rehabilitation was continued. Since AM’s speech production was still very slow, reduced,
                                                                                                and agrammatic, the main objective of therapy was to have the patient speak more
                                                                                                fluently with more verbs. Oral and written confrontation naming and retrieval of actions
                                                                                                were added, in the hope that a richer vocabulary would induce AM to speak more. The
                                                                                                language examination had shown that comprehension was superior to his speech
                                                                                                production. It was therefore not thought to be a problem and was not specifically
                                                                                                retrained. In June 1990, after a year of daily rehabilitation, a very mild across-the-board
314     BASSO AND CAPORALI


                                                                                                recovery was detectable (Basso & Vignolo, 1974), except for the Token Test score which
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                                                                                                was only 18. Confrontation naming was now 90% correct and written confrontation
                                                                                                naming 40%; reading aloud of sentences was 70% and repetition and writing to dictation
                                                                                                of sentences, although still severely impaired, were better than at first examination
                                                                                                (Figure 2). This degree of recovery, however, was apparently not sufficient to bring about
                                                                                                a change in his spontaneous production and did not show up in his daily life.
                                                                                                Communication was still very difficult (see Appendix) and AM did not try to speak with
                                                                                                members of his family or other people. Recovery showed up only in the rehabilitation
                                                                                                setting.
                                                                                                   The patient was young and highly motivated, and we did not understand why he did
                                                                                                not use his speech outside the rehabilitation setting. Moreover, his speech therapist was
                                                                                                firmly convinced that she could obtain more from him. Rehabilitation was continued for a
                                                                                                year, 5 days a week with the only interruption the summer break, but without any further
                                                                                                recovery. Between June 1990 and July 1991 he was tested on three further occasions but
                                                                                                no amelioration was noted (in all testing sessions, for instance, the Token Test score was
                                                                                                18).
                                                                                                   Figures 1 and 2 report percentage of correct responses by the two patients in the
                                                                                                language tasks. The two patients were examined with two different language
                                                                                                examinations (Basso & Vignolo, 1974; Ciurli et al., 1996). The two tests have been
                                                                                                devised for severe aphasic patients and all tasks are easily performed by normal subjects
                                                                                                with a ceiling effect. The stimuli used differ in the two batteries but the tasks are the same
                                                                                                and can easily be compared. The main difference between the two tests lies in the
                                                                                                sentence production task (see later).


                                                                                                Comparison
                                                                                                FC and AM were two men of similar age though their educational level was different (13
                                                                                                vs 8 years). They presented with very similar language disorder 20 and 11 months post-
                                                                                                onset when they started rehabilitation at the Aphasia Unit of Milan University. Both had
                                                                                                mild right hemiplegia without visual field defects. Comparison of their CT lesions
                                                                                                showed that they were similar although the cortical area involved in FC’s lesion was
                                                                                                slightly larger as was AM’s extension to the deep structures.
                                                                                                   Both had previously been treated for aphasia with similar regimens. From their clinical
                                                                                                reports it would appear that initially they both had global aphasia which recovered to a
                                                                                                point that it could be reclassified as mixed nonfluent aphasia; in other words,
                                                                                                comprehension had partially recovered in both patients. Both presented with severely
                                                                                                reduced speech and mild verbal apraxia; agrammatism became evident in both patients
                                                                                                when their speech production became slightly more abundant.
                                                                                                   To recapitulate, except for the educational level, FC and AM had similar demographic
                                                                                                characteristics, aetiology, aphasia profiles, and previous therapy regimen when we met
                                                                                                them.
                                                                                                   Rehabilitation was then started with similar objectives: to reduce their verbal apraxia,
                                                                                                to augment speech output, and to prevent agrammatism. In neither case was
                                                                                                comprehension specifically rehabilitated: AM initially showed an important recovery
                                                                                                of comprehension and it was thought that conversation could be a sufficient stimulation
                                                                                                for FC’s comprehension. The therapy programmes were not much different and were
                                                                                                carried out by the same therapist. The only important difference was the amount of time
                                                                                                spent in therapy: 1 hour 5 days a week for AM, and no less than 2–3 hours 7 days per
                                                                                                week for FC. After a year, at testing AM’s comprehension, albeit still severely impaired,
APHASIA THERAPY        315

                                                                                                had recovered slightly more than FC’s, and FC produced much more and was more
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                                                                                                communicative than AM. Direct comparison of their production poses a problem because
                                                                                                FC was asked to describe a picture and AM to explain how to shave, and procedural
                                                                                                language can be more difficult than description of a picture for aphasic patients.
                                                                                                However, FC’s production clearly shows a continuous recovery and AM’s production
                                                                                                does not change much (see Appendix). The difference between the two patients was
                                                                                                clearly evident in ecological situations. AM was reported never to start talking or
                                                                                                participate in a conversation even with his family members. FC talks more with more
                                                                                                people and although his comprehension is severely impaired on testing, he rarely has
                                                                                                problems comprehending what is said to him.
                                                                                                   A second year of therapy did not result in any further recovery in AM; FC is still being
                                                                                                rehabilitated and there is no indication that a plateau has been reached.

                                                                                                                          PAIR 2: PATIENTS DT AND SB
                                                                                                Patient DT
                                                                                                At the beginning of March 1996 DT, a 35-year-old right-handed man with a degree in
                                                                                                architecture, suffered a subarachnoid haemorrhage caused by an existing arterio-venous
                                                                                                malformation. He was immediately admitted to the local hospital, where the neurological
                                                                                                examination showed intense rigor without focal neurological signs. An angiography
                                                                                                demonstrated a large aneurysm at the origin of the left communicating posterior artery.
                                                                                                Five days later DT was operated on and three days after the intervention he became
                                                                                                drowsy and showed a mild right hemiparesis and aphasia. Successive CT-scans showed a
                                                                                                progressive enlargement of the ventricles. Two weeks after the first intervention, he was
                                                                                                again operated on and a ventricular peritoneal shunt was positioned with progressive
                                                                                                recovery of consciousness. At the end of April he was discharged from hospital. The
                                                                                                neurological examination showed global aphasia without hemiparesis or hemianopia. In
                                                                                                September 1996 a CT scan showed a frontal hypodense lesion. He started aphasia
                                                                                                rehabilitation while in hospital, and it was still going on when he was first seen at the
                                                                                                Aphasia Unit at Milan University in September 1996, six months post-onset.
                                                                                                   Language examination (Basso & Vignolo, 1974) disclosed global aphasia with severe
                                                                                                acalculia (12/101); oral (17/20) and ideomotor (71/72) apraxia were not present. His
                                                                                                spontaneous speech was scanty, apparently without verbal apraxia but totally
                                                                                                incomprehensible; he uttered short sequences of phonemes and sometimes such words
                                                                                                as ‘‘is, a, so’’ (see Appendix). Oral and written comprehension of words was possible
                                                                                                (75% and 85%) but it was severely impaired for short commands (30 and 40%
                                                                                                respectively). He scored 2/36 on the Token Test. Repetition, reading aloud, and writing to
                                                                                                dictation were all nil but he could copy some words. His score on the Raven’s Coloured
                                                                                                Progressive Matrices was 24/36 (Figure 3).
                                                                                                   At that time it was not possible to involve the patient in a decision about rehabilitation
                                                                                                because he appeared not to realise how severe his deficit was and it was very difficult to
                                                                                                make him understand what was said to him, even when he himself was the subject of the
                                                                                                conversation. However, the family was very supportive and an aunt had plenty of time to
                                                                                                dedicate to the patient. As for DT, he had a rather passive attitude but was always willing
                                                                                                to do what he was asked. We therefore thought that we could rely on the family and
                                                                                                planned a therapeutic intervention that did not require DT to work alone. He lived rather
                                                                                                far from Milan but we decided, together with his family, that for the present time it was
                                                                                                better to come to Milan every morning and work at home in the afternoon, as we were not
                                                                                                convinced that a lay person could manage all the tasks we considered necessary.
316         BASSO AND CAPORALI


                                                                                                    September 1996 (Basso & Vignolo, 1974)                                                            TT =2/36 Rv =24/36
Downloaded By: [Universidad Michoacana de San Nicolás de Hidalgo] At: 01:13 19 September 2007




                                                                                                      100
                                                                                                       90
                                                                                                       80
                                                                                                       70
                                                                                                       60
                                                                                                       50
                                                                                                       40
                                                                                                       30
                                                                                                       20
                                                                                                       10
                                                                                                        0
                                                                                                               N       V      S     N       V      S     N     S    N     S     N      S        N      S      N      S
                                                                                                                     (n.t.)               (n.t.)

                                                                                                               Oral Production     Written Production      Oral      Written    Repetition      Reading       Writing to
                                                                                                                                                        Comprehen. Comprehen.                    aloud        dictation




                                                                                                            June 1997 (Miceli et al., 1991)                                                      TT = 11/36    Rv = 29/36

                                                                                                      100
                                                                                                       90
                                                                                                       80
                                                                                                       70
                                                                                                       60
                                                                                                       50
                                                                                                       40
                                                                                                       30
                                                                                                       20
                                                                                                       10
                                                                                                        0
                                                                                                               N       V      S     N         V    S     N     S    N     S     N      S        N      S      N       S
                                                                                                                                                                                                                    (n.t.)

                                                                                                               Oral Production     Written Production      Oral      Written    Repetition      Reading       Writing to
                                                                                                                                                        Comprehen. Comprehen.                    aloud        dictation




                                                                                                        January 2000 (Miceli et al., 1991)                                                   TT = 19/36 (written = 31/36)
                                                                                                                                                                                             Rv = 36/36
                                                                                                      100
                                                                                                       90
                                                                                                       80
                                                                                                       70
                                                                                                       60
                                                                                                       50
                                                                                                       40
                                                                                                       30
                                                                                                       20
                                                                                                       10
                                                                                                        0
                                                                                                               N       V      S     N         V    S     N     S    N     S     N      S        N      S      N       S
                                                                                                                                                                                                                    (n.t.)

                                                                                                               Oral Production     Written Production      Oral      Written    Repetition      Reading       Writing to
                                                                                                                                                        Comprehen. Comprehen.                    aloud        dictation



                                                                                                   TT = Token Test; RV = Raven’s Matrices; N = nouns; V = verbs; S = sentences;n.t. = not tested.

                                                                                                Figure 3. Percentage correct responses by DT at three subsequent evaluations: September, 1996; June, 1997;
                                                                                                January, 2000.



                                                                                                   Because almost everything the patient tried to do resulted in a failure, it was
                                                                                                decided that the family should start with what can appear a very easy task: DT had
                                                                                                to repeat syllables or short words, whichever was more successful. In fact this proved
                                                                                                to be very difficult for DT and required a lot of skill and patience on the part of
                                                                                                his aunt. After he succeeded in repeating a few words and syllables, reading and
                                                                                                writing of syllables was introduced; mostly, however, these were accomplished by
                                                                                                repetition and copying.
APHASIA THERAPY         317

                                                                                                    The therapist took on the difficult task of having DT say some content words that were
Downloaded By: [Universidad Michoacana de San Nicolás de Hidalgo] At: 01:13 19 September 2007




                                                                                                totally absent from his speech. She could not rely on such classical facilitation as repetition
                                                                                                or reading because DT could do neither. As for phonemic cueing it was sometimes, albeit
                                                                                                rarely, successful but its effectiveness was very short-lived. We gave up the idea of
                                                                                                obtaining a target content word in a convergent task, such as confrontation naming, and we
                                                                                                tried to elicit them in more divergent and open tasks, accepting any content word DT would
                                                                                                produce. For instance, we said a word and asked DT to say the first word that came into his
                                                                                                mind or to complete a sentence with any word he could think of. Any content word DT said
                                                                                                was repeated by the therapist and then included in a sentence, hoping that this would help
                                                                                                DT become conscious of what he had said, if by chance he had produced the word
                                                                                                automatically without really being aware of its meaning.
                                                                                                    Comprehension exercises of words and sentences such as pointing to pictures were not
                                                                                                used. We decided that continuous verbal interactions with the therapist and his aunt
                                                                                                would provide sufficient stimulation and we argued that this would be a more dynamic
                                                                                                and ecological exercise.
                                                                                                    A re-evaluation 3 months later showed slight improvement in repetition and reading
                                                                                                aloud that were now possible for some words and nonwords. Moreover, DT was now
                                                                                                more conscious of his difficulties and he was more motivated in his rehabilitation. This
                                                                                                allowed us to increase his homework. As he could now write some words he was also
                                                                                                asked to do written naming at home, especially action naming, with the help of his aunt.
                                                                                                    Six months after starting rehabilitation he was again reassessed (Miceli, Laudanna, &
                                                                                                Burani, 1991). His speech output was severely reduced and anomic; he sometimes
                                                                                                omitted verbs and prepositions. Notwithstanding frequent omissions and phonemic
                                                                                                paraphasias, when speaking he could make himself understood, being very good at using
                                                                                                gestures, mime and drawings. He could name about 60% of object pictures and 30% of
                                                                                                action pictures. Comprehension was adequate in conversation but still severely impaired
                                                                                                on the Token Test (13/36). Repetition and reading aloud were still very severely
                                                                                                impaired.
                                                                                                    DT had always been very keen to resume work, which he apparently could do. He was
                                                                                                a fashion designer for a glamorous Italian fashion house. His drawing capacity was
                                                                                                unaltered and he decided to go to work at least twice a week and come to Milan the other
                                                                                                3 days, working at home in the afternoons and the evenings. This regimen did not last
                                                                                                long and he soon resumed work 5 days a week coming to Milan once every 3–4 weeks.
                                                                                                After an initial period in which he gave up his commitment to rehabilitation because
                                                                                                working was both tiring and very involving for DT, his homework has always been
                                                                                                regular and intensive.
                                                                                                    Reassessed in June 1997 (Miceli et al., 1991), 15 months post-onset and 9 months after
                                                                                                starting rehabilitation, he showed an across-the-board recovery but was still impaired in
                                                                                                all tasks. Some peaks of impairment were evident. Reading and repetition were
                                                                                                particularly difficult for him; he read very slowly, recognising one letter at a time.
                                                                                                However, if given enough time he could correctly read 70% of words and 50% of short
                                                                                                sentences. Repetition was made difficult, besides other reasons, by the fact that he had
                                                                                                difficulties identifying heard phonemes; the contrast voiced–voiceless, for instance, was
                                                                                                beyond his possibilities. His Token Test score was 11/36. However, his vocabulary was
                                                                                                richer, his production more abundant but still agrammatic. His comprehension in
                                                                                                conversation was fair, and his writing easier (Figure 3). The Appendix reports his
                                                                                                retelling of a typical day.
                                                                                                    The same regimen was continued for the following two and a half years. Regular
                                                                                                control examinations showed slow but continued recovery. Treatment was changed
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A P H A S I O L O G Y

  • 1. This article was downloaded by:[Universidad Michoacana de San Nicolás de Hidalgo] On: 19 September 2007 Access Details: [subscription number 780340729] Publisher: Psychology Press Informa Ltd Registered in England and Wales Registered Number: 1072954 Registered office: Mortimer House, 37-41 Mortimer Street, London W1T 3JH, UK Aphasiology Publication details, including instructions for authors and subscription information: http://www.informaworld.com/smpp/title~content=t713393920 Aphasia Therapy or The importance of being earnest Anna Basso a; Alessandra Caporali a a Milan University, Italy. Online Publication Date: 01 April 2001 To cite this Article: Basso, Anna and Caporali, Alessandra (2001) 'Aphasia Therapy or The importance of being earnest', Aphasiology, 15:4, 307 - 332 To link to this article: DOI: 10.1080/02687040042000304 URL: http://dx.doi.org/10.1080/02687040042000304 PLEASE SCROLL DOWN FOR ARTICLE Full terms and conditions of use: http://www.informaworld.com/terms-and-conditions-of-access.pdf This article maybe used for research, teaching and private study purposes. Any substantial or systematic reproduction, re-distribution, re-selling, loan or sub-licensing, systematic supply or distribution in any form to anyone is expressly forbidden. The publisher does not give any warranty express or implied or make any representation that the contents will be complete or accurate or up to date. The accuracy of any instructions, formulae and drug doses should be independently verified with primary sources. The publisher shall not be liable for any loss, actions, claims, proceedings, demand or costs or damages whatsoever or howsoever caused arising directly or indirectly in connection with or arising out of the use of this material.
  • 2. APHASIOLOGY, 2001, 15 (4), 307–332 Downloaded By: [Universidad Michoacana de San Nicolás de Hidalgo] At: 01:13 19 September 2007 Aphasia Therapy or The importance of being earnest Anna Basso and Alessandra Caporali Milan University, Italy Effectiveness of aphasia therapy, at least for some patients, is no longer under discussion but the specific effect of most of the variables influencing recovery is unknown. In this paper we address a question relative to the therapeutic regimen. Three pairs of patients with similar age, educational level, sex, aetiology, lesion site, and type and severity of aphasia are compared. Except for one of the control patients who was 2 months post-onset, all patients were at least 6 months post-onset (range: 6–22 months) and had already been rehabilitated when they entered the study. The three experimental subjects underwent a very long and intensive therapeutic programme (2/3 hours per day, 7 days per week, for many months), with the help of the family and volunteers. The control patients were rehabilitated daily (1 hour, 5 days a week) for similar periods of time. It is argued that the intensive treatment achieved higher test scores and more prolonged recovery and that the experimental patients made better use of their recovered language in daily life. INTRODUCTION It is now generally agreed that aphasia therapy can be effective, namely that an aphasic patient will have better chances of recovery if he or she is rehabilitated. Experimental evidence comes from group studies (Basso, Capitani, & Vignolo, 1979; Basso, Faglioni, & Vignolo, 1975; Gloning, Trappl, Heiss, & Quatember, 1976; Hagen, 1973; Mazzoni et al, 1995; Poeck, Huber, & Willmes, 1989) and single case studies (Byng, 1988; De Partz, 1986; Jones, 1986). The beneficial effect of therapy is also confirmed by results of meta- analyses (Robey, 1994, 1998). In his 1998 study, Robey reviewed 55 reports on the effectiveness of aphasia therapy and studied whether there is a difference between treated and untreated patients. The reanalysis of the data showed a distinction between treated and untreated patients, which exceeded the criterion value for a medium-sized effect. However, the question is far from being settled because we still need to know which patients (or, perhaps better, which impairments) can be profitably rehabilitated and how. In a few single case studies both the impairment and the intervention have been described in a sufficiently detailed way so as to be reproducible (Byng, 1988; De Partz, 1986; Jones, 1986; Miceli, Amitrano, Capasso, & Caramazza, 1996). However, we do not know whether other variables (such as the associated disorders or the therapeutic regimen) have an effect on recovery and therefore we cannot be sure whether another patient showing Address correspondenc e to: Anna Basso, Neurological Clinic, Via F. Sforza 35, 20122 Milan, Italy. Email: abasso@micronet.it # 2001 Psychology Press Ltd http://www.tandf.co.uk/journals/pp/02687038.html DOI:10.1080/02687040042000304
  • 3. 308 BASSO AND CAPORALI the same functional impairment (but different in other respects) would benefit from the Downloaded By: [Universidad Michoacana de San Nicolás de Hidalgo] At: 01:13 19 September 2007 same intervention. A theory of rehabilitation should comprise various aspects, the most important being the intervention strategies themselves. Other important aspects are the characteristics of the patient (such as age and education), the functional damage (impaired word comprehension, impaired lexical reading, and so on), and the therapeutic regimen. In this paper we shall address a question relative to the therapeutic regimen. In the literature there are some descriptions of patients who have benefited from very brief periods of therapeutic interventions (see, for instance, Byng, 1988; Marshall, Pound, White-Thompson, & Pring, 1990; Penn, 1993). In the majority of cases these are chronic patients who can be used as their own controls. After having received what is generally called traditional therapy and having reached a plateau, they are offered a new method and show recovery of the treated impairment. TC (Penn, 1993), for instance, was a multilingual aphasic patient 9 months post-onset who ‘‘had a mild aphasia with relatively intact receptive abilities, fluent output, and marked word-finding difficulty’’ (p. 36) when a discourse-based therapy programme was implemented. The programme was carried out in nine sessions after which ‘‘improvement in the target areas was noted in all languages despite the fact that therapy was conducted only in English; the specific targeted behaviors (. . .) were assessed as being markedly more appropriate across the tested languages’’ (Penn, 1993, p. 40). BRB (Byng, 1988), a frequently cited case, was 6 years post-onset (during which time he had been rehabilitated) when he received a specific programme for mapping thematic roles onto grammatical relations. Therapy consisted of two sessions a week apart and intervening homework. BRB showed marked improvement in his comprehension of locative sentences (which had been the object of therapy) and of simple reversible sentences, as well as in sentence production, which had not been rehabilitated. Unfortunately this has never been our experience. We have seen patients recover with therapy, but following intensive treatment. Over the years we have been augmenting what we considered the minimum duration and intensity of aphasia rehabilitation necessary for recovery to show up in daily life, also in view of the fact that there is some experimental evidence that to be effective rehabilitation must be intensive and protracted (see Basso, 1992 for a review). The regimen we now offer to our patients generally consists of 1-hour daily sessions, supported by intensive homework (2–3 hours per day) and protracted for many months with control examinations every 3 months. The rationale for discontinuing the therapy is no recovery between two successive control examinations. This regimen in not easy to implement. We must first persuade the patient and his or her family that this is necessary and then help them to find a way to implement the necessary homework. With the help of the family, we try to identify a relative, a friend, or a volunteer who can do it. We must also identify the objectives of the rehabilitation programme that can be pursued by a lay person and the exercises that can be carried out by the patient alone. The focus of this paper is the regimen of aphasia therapy. The paper does not raise the issue of the content of therapy nor does it discuss our approach, which is described in some detail elsewhere (Basso, 1977, 1999). Briefly, we can say that in our aphasia unit we adopt two rather different approaches. In those cases in which we can arrive at a precise functional diagnosis with reference to a cognitive neuropsychologica l model of normal processing, we endeavour to target the identified impairment/s and implement what could be broadly defined as a cognitive neuropsychologica l approach. For severely
  • 4. APHASIA THERAPY 309 damaged patients with an across-the-board impairment, less analytic approaches targeting Downloaded By: [Universidad Michoacana de San Nicolás de Hidalgo] At: 01:13 19 September 2007 the disability itself can prove efficacious. By way of example, if a patient has an understanding disorder that can be explained by, say, damage to the input lexicon, it appears obvious to target the damaged lexicon. If, however, comprehension is severely impaired and the patient fails all tasks, a cognitive diagnosis is still possible but it is not really helpful in dictating what to do. We prefer to rehabilitate comprehension as a global behaviour in more ecological settings such as a conversation. The principal function of language is to permit communication among human beings and the main goal of rehabilitation is to enable the patient to communicate through language. To communicate the patient must be able to understand what his or her interlocutor is saying and to express what he or she wants to say. In this sort of therapy, the therapist engages the patient in a conversation which must be as similar as possible to a natural conversation the patient may want to sustain in his or her daily life. Right from the beginning of the treatment the patient’s participation must be similar to normal conversational behaviour. For each patient we also identify specific goals (reduction of apraxia of speech, prevention of agrammatism, recovery of word-finding abilities, reading aloud, and so on) with the aim of setting the stage for a successive and more specific intervention. If we want to label our intervention strategies, it can perhaps be suggested that for severe aphasic patients our intervention can be considered loosely akin to the so-called stimulation approach (see Howard & Hatfield, 1987, for a review). In this paper we attempt to demonstrate that an intensive therapeutic regimen can cause such a degree of recovery as to show up in the patient’s daily living. We are not investigating the outcome of therapy for a well-defined task such as, for instance, naming of 50 action pictures or reading of nonwords. We compare three pairs of patients matched as far as possible for the variables known to influence recovery. They have all been re- educated for long periods of time, the main difference being the intensity of the rehabilitation: the three control patients were seen by the speech therapist for 1 hour 5 days per week, the three experimental patients were seen for 5 hours per week and were also helped at home 2–3 hours per day. PAIR 1: PATIENTS FC AND AM Patient FC FC was a 37-year-old right-handed mechanic with 13 years of education who suffered a CVA in June 1997; his previous medical history was uneventful. He was admitted unconscious to hospital where a CT-scan showed ischaemic damage to the left frontal- temporal-parietal area surrounde d by oedema. Neurological assessment immediately post-stroke indicated global aphasia and right hemiplegia. The patient recovered clear consciousness in the following days and underwent motor rehabilitation. A MRI performed in April 1999 showed a large temporal-parietal lesion with extensive involvement of the white matter and the subcortical structures. When discharged from the hospital in August, FC was admitted to a rehabilitation clinic where he started language rehabilitation, 5 days a week, until November when he went home. He continued language rehabilitation in the same clinic on an outpatient basis four times per week during the first months, which reduced to three and then two times a week. He had been dismissed from rehabilitation when first seen at the Aphasia Unit of Milan University in February 1999, 20 months post-stroke, after being told that no further recovery was possible.
  • 5. 310 BASSO AND CAPORALI The language examination (Ciurli, Marangolo, & Basso, 1996) at this time Downloaded By: [Universidad Michoacana de San Nicolás de Hidalgo] At: 01:13 19 September 2007 demonstrated that it was not possible to classify FC’s language impairments into any of the classical syndromes, and a diagnosis of mixed nonfluent aphasia (Goodglass & Kaplan, 1983) was considered appropriate. He also showed verbal apraxia and acalculia (on a written calculation test he scored 15/101; cut-off score: 74/101; Basso & Capitani, 1979). He had no oral apraxia (20/20; cut-off score: 17/20; De Renzi, Pieczuro, & Vignolo, 1966) or ideomotor apraxia (67/72; cut-off score: 53/72; De Renzi, Motti, & Nichelli, 1980). His speech was impoverished and scanty; few isolated words (generally nouns) were produced with long pauses. Naming of object pictures was 60% correct, naming of action pictures was 30% correct. FC did not try to express himself using gestures or any other nonverbal means; he rarely looked at the interlocutor and appeared to be concentrating on trying to find the words to make himself understood. When his attention was caught, comprehension was sufficient for simple questions but severely impaired on the Token Test (13/36; cut-off score: 29/36; De Renzi & Faglioni, 1978). Reading comprehension was at the same level as auditory comprehension. Reading aloud and repetition were possible for single words but not for sentences; writing was impossible except for copying which was generally correct. He scored 34/36 on the Raven’s Coloured Progressive Matrices (Figure 1). The Appendix reports his description of the picture of a drawing room where a woman is knitting, a man is reading a newspaper, a girl is watching television, a boy is playing with blocks and a cat with a ball of wool. FC had come to see us because he did not want to give up therapy. Mainly in consideration of his young age, we thought this worthwhile notwithstanding two important negative factors: the time elapsed since onset and the fact that the patient had already been re-educated for 18 months. We discussed with FC and his wife the fact that in our opinion his only chance of recovery depended on very hard and lasting work he would have to do by himself, with a friend or a relative under our supervision, and directly with us. Even in this case chances of recovery were rather poor because the period of spontaneous recovery had finished long ago and he had already been re- educated for a long period of time, although lately rehabilitation had been reduced. FC and his wife agreed to do all they could. Because his wife worked and was away all day, she could dedicate only an hour per day, in the evening, to her husband, with more time at weekends. They found a young woman to work at home with him two more hours per day and he received treatment at the Aphasia Unit for an hour daily. Initially his homework consisted of sentence repetition and written action naming, tasks that a lay person can easily handle. FC’s wife and assistant were shown how to work with the patient and they regularly came to the clinic for supervision. Repetition was chosen because it could help FC overcome his verbal apraxia (which was not very severe), give him confidence in his capacity to produce sentences, and hopefully help prevent the production of agrammatic sentences (Beyn & Shokhor-Trotskaya , 1966). Written naming was considered important because of FC’s markedly reduced vocabulary, and actions instead of nouns were chosen because he was inclined to use only nouns in speech and we thought that facilitating retrieval of verbs could be helpful in preventing or reducing agrammatism. The therapist reserved for herself that which we thought was more difficult to delegate. During the evaluation it had become clear that FC had severe difficulties in having a conversation; he was eager to speak (frequently without succeeding in making the interlocutor understand what he was talking about) but would not pay attention to what was said to him. This made it very difficult to help him express himself by asking adequate questions. It was then decided that the therapist would involve the patient in a
  • 6. APHASIA THERAPY 311 Downloaded By: [Universidad Michoacana de San Nicolás de Hidalgo] At: 01:13 19 September 2007 February 1999 (Ciurli et al. 1996) TT = 13/36 Rv = 34/36 100 90 80 70 60 50 40 30 20 10 0 N V S N V S N S N S N S N S N S Oral Production Written Production Oral Written Repetition Reading Writing to Comprehen. Comprehen. aloud dictation October 1999 (Ciurli et al. 1996) TT = 13/36 Rv = 36/36 100 90 80 70 60 50 40 30 20 10 0 N V S N V S N S N S N S N S N S Oral Production Written Production Oral Written Repetition Reading Writing to Comprehen. Comprehen. aloud dictation April 2000 (Ciurli et al. 1996) TT = 16/36 Rv = 50/60 100 90 80 70 60 50 40 30 20 10 0 N V S N V S N S N S N S N S N S Oral Production Written Production Oral Written Repetition Reading Writing to Comprehen. Comprehen. aloud dictation TT = Token Test; RV = Raven’s Matrices; N = nouns; V = verbs; S = sentences. Figure 1. Percentage correct responses by FC at three subsequent evaluations: February, 1999, October, 1999; April, 2000. conversation, rapidly changing the subject of the conversation and getting the patient accustomed to answering in any possible way. A control evaluation 3 months later did not disclose much change, except for oral action naming which was now 80% correct. We were not discouraged because we had not expected much improvement in 3 months and therapy was continued. At home he was required to read aloud (which he could do by himself) and to decline verbs he had first retrieved in the infinitive form. With the therapist he now started to read
  • 7. 312 BASSO AND CAPORALI a short paragraph, imagine a scene that represented what he had read and, when he could Downloaded By: [Universidad Michoacana de San Nicolás de Hidalgo] At: 01:13 19 September 2007 clearly see the scene in his mind’s eye, describe it. This was thought to help him speak because the content of the message was already clear in his mind; at the same time the therapist did not know in advance what he was going to say and therefore it had a communicative value. A second control examination in October 1999 (Ciurli et al., 1996) disclosed a generalised although mild improvement in all language tasks. He was given a score of 5/ 10 for his description of a picture (see Appendix) and he could write some words to dictation and in a confrontation naming task. However, he still scored 13/36 on the Token Test (Figure 1). Rehabilitation continued without any important change and a final control examination was carried on in April 2000, after 14 months of intensive language therapy (Ciurli et al., 1996). Improvement was now evident in all tasks and his speech output was more abundant and more informative. Confrontation naming of nouns was 85% correct and of actions 70% correct, and he could write to confrontation 70% of nouns and 60% of actions. It was now possible for him to read and repeat short sentences. Only his score on the Token Test was not much changed (16/36) (Figure 1). His comprehension in a conversation, however, was quick and correct. His production was more abundant and informative although still agrammatic with some correct sentences, and he did not wait to be asked something but frequently introduced new topics. The appendix reports his retelling of a typical day. Patient AM AM was a 37-year-old right-handed bookbinder with 8 years of formal education who suffered a CVA in July 1988. On admission to the hospital the neurological examination showed mild right hemiparesis and expressive aphasia. A CT scan performed in October 1988 disclosed a large left temporal-parietal lesion with deep extension to the basal ganglia. AM started daily language rehabilitation in September, which was still going on in June 1989, 11 months post-onset, when he was first examined at the Aphasia Unit. The language examination (Basso & Vignolo, 1974) disclosed a mixed nonfluent aphasia with severely reduced speech and verbal apraxia. His description of how to shave is reported in the Appendix. Repetition and reading aloud were only mildly impaired for words and nonwords but he could not repeat or read sentences. Writing was more severely impaired than oral speech; he could sign and copy and he correctly wrote only one of 20 words. Comprehension was adequate for oral and written words and sentences; on the Token Test he scored 15/36. He had no oral (17/20) or ideomotor (69/72) apraxia and scored 30/36 on the Raven’s Coloured Progressive Matrices. In the written calculation test he scored 12/101 (Figure 2). Rehabilitation in our unit was started, an hour daily, with the immediate objectives of reducing AM’s verbal apraxia by having him repeat short sentences. It was also thought that this could prevent or reduce agrammatism. In order to augment his speech output and his vocabulary he was engaged in conversations above various subjects and asked to describe pictures. A control examination 6 months later, in December 1989 (Basso & Vignolo, 1974), showed some recovery of speech production, which was now agrammatic but slightly more fluent (see Appendix), and in writing of single words. His comprehension as evaluated by the Token Test was much better (22/36). He scored 30/36 on the Raven’s Coloured Progressive Matrices and 8/101 in the written calculation test (Figure 2). Daily
  • 8. APHASIA THERAPY 313 Downloaded By: [Universidad Michoacana de San Nicolás de Hidalgo] At: 01:13 19 September 2007 June 1989 (Basso & Vignolo, 1974) TT = 15/36 Rv = 30/36 100 90 80 70 60 50 40 30 20 10 0 N V S N V S N S N S N S N S N S (n.t.) (n.t.) Oral Production Written Production Oral Written Repetition Reading Writing to Comprehen. Comprehen. aloud dictation December 1989 (Basso & Vignolo, 1974) TT = 22/36 Rv = 30/36 100 90 80 70 60 50 40 30 20 10 0 N V S N V S N S N S N S N S N S (n.t.) (n.t.) Oral Production Written Production Oral Written Repetition Reading Writing to Comprehen. Comprehen. aloud dictation June 1990 (Basso & Vignolo, 1974) TT =18/36 Rv = 33/36 100 90 80 70 60 50 40 30 20 10 0 N V S N V S N S N S N S N S N S (n.t.) (n.t.) Oral Production Written Production Oral Written Repetition Reading Writing to Comprehen. Comprehen. aloud dictation TT = Token Test; RV = Raven’s Matrices; N = nouns; V = verbs; S = sentences; n.t. = not tested. Figure 2. Percentage correct responses by AM at three subsequen t evaluations: June, 1989; December, 1989; June, 1990. rehabilitation was continued. Since AM’s speech production was still very slow, reduced, and agrammatic, the main objective of therapy was to have the patient speak more fluently with more verbs. Oral and written confrontation naming and retrieval of actions were added, in the hope that a richer vocabulary would induce AM to speak more. The language examination had shown that comprehension was superior to his speech production. It was therefore not thought to be a problem and was not specifically retrained. In June 1990, after a year of daily rehabilitation, a very mild across-the-board
  • 9. 314 BASSO AND CAPORALI recovery was detectable (Basso & Vignolo, 1974), except for the Token Test score which Downloaded By: [Universidad Michoacana de San Nicolás de Hidalgo] At: 01:13 19 September 2007 was only 18. Confrontation naming was now 90% correct and written confrontation naming 40%; reading aloud of sentences was 70% and repetition and writing to dictation of sentences, although still severely impaired, were better than at first examination (Figure 2). This degree of recovery, however, was apparently not sufficient to bring about a change in his spontaneous production and did not show up in his daily life. Communication was still very difficult (see Appendix) and AM did not try to speak with members of his family or other people. Recovery showed up only in the rehabilitation setting. The patient was young and highly motivated, and we did not understand why he did not use his speech outside the rehabilitation setting. Moreover, his speech therapist was firmly convinced that she could obtain more from him. Rehabilitation was continued for a year, 5 days a week with the only interruption the summer break, but without any further recovery. Between June 1990 and July 1991 he was tested on three further occasions but no amelioration was noted (in all testing sessions, for instance, the Token Test score was 18). Figures 1 and 2 report percentage of correct responses by the two patients in the language tasks. The two patients were examined with two different language examinations (Basso & Vignolo, 1974; Ciurli et al., 1996). The two tests have been devised for severe aphasic patients and all tasks are easily performed by normal subjects with a ceiling effect. The stimuli used differ in the two batteries but the tasks are the same and can easily be compared. The main difference between the two tests lies in the sentence production task (see later). Comparison FC and AM were two men of similar age though their educational level was different (13 vs 8 years). They presented with very similar language disorder 20 and 11 months post- onset when they started rehabilitation at the Aphasia Unit of Milan University. Both had mild right hemiplegia without visual field defects. Comparison of their CT lesions showed that they were similar although the cortical area involved in FC’s lesion was slightly larger as was AM’s extension to the deep structures. Both had previously been treated for aphasia with similar regimens. From their clinical reports it would appear that initially they both had global aphasia which recovered to a point that it could be reclassified as mixed nonfluent aphasia; in other words, comprehension had partially recovered in both patients. Both presented with severely reduced speech and mild verbal apraxia; agrammatism became evident in both patients when their speech production became slightly more abundant. To recapitulate, except for the educational level, FC and AM had similar demographic characteristics, aetiology, aphasia profiles, and previous therapy regimen when we met them. Rehabilitation was then started with similar objectives: to reduce their verbal apraxia, to augment speech output, and to prevent agrammatism. In neither case was comprehension specifically rehabilitated: AM initially showed an important recovery of comprehension and it was thought that conversation could be a sufficient stimulation for FC’s comprehension. The therapy programmes were not much different and were carried out by the same therapist. The only important difference was the amount of time spent in therapy: 1 hour 5 days a week for AM, and no less than 2–3 hours 7 days per week for FC. After a year, at testing AM’s comprehension, albeit still severely impaired,
  • 10. APHASIA THERAPY 315 had recovered slightly more than FC’s, and FC produced much more and was more Downloaded By: [Universidad Michoacana de San Nicolás de Hidalgo] At: 01:13 19 September 2007 communicative than AM. Direct comparison of their production poses a problem because FC was asked to describe a picture and AM to explain how to shave, and procedural language can be more difficult than description of a picture for aphasic patients. However, FC’s production clearly shows a continuous recovery and AM’s production does not change much (see Appendix). The difference between the two patients was clearly evident in ecological situations. AM was reported never to start talking or participate in a conversation even with his family members. FC talks more with more people and although his comprehension is severely impaired on testing, he rarely has problems comprehending what is said to him. A second year of therapy did not result in any further recovery in AM; FC is still being rehabilitated and there is no indication that a plateau has been reached. PAIR 2: PATIENTS DT AND SB Patient DT At the beginning of March 1996 DT, a 35-year-old right-handed man with a degree in architecture, suffered a subarachnoid haemorrhage caused by an existing arterio-venous malformation. He was immediately admitted to the local hospital, where the neurological examination showed intense rigor without focal neurological signs. An angiography demonstrated a large aneurysm at the origin of the left communicating posterior artery. Five days later DT was operated on and three days after the intervention he became drowsy and showed a mild right hemiparesis and aphasia. Successive CT-scans showed a progressive enlargement of the ventricles. Two weeks after the first intervention, he was again operated on and a ventricular peritoneal shunt was positioned with progressive recovery of consciousness. At the end of April he was discharged from hospital. The neurological examination showed global aphasia without hemiparesis or hemianopia. In September 1996 a CT scan showed a frontal hypodense lesion. He started aphasia rehabilitation while in hospital, and it was still going on when he was first seen at the Aphasia Unit at Milan University in September 1996, six months post-onset. Language examination (Basso & Vignolo, 1974) disclosed global aphasia with severe acalculia (12/101); oral (17/20) and ideomotor (71/72) apraxia were not present. His spontaneous speech was scanty, apparently without verbal apraxia but totally incomprehensible; he uttered short sequences of phonemes and sometimes such words as ‘‘is, a, so’’ (see Appendix). Oral and written comprehension of words was possible (75% and 85%) but it was severely impaired for short commands (30 and 40% respectively). He scored 2/36 on the Token Test. Repetition, reading aloud, and writing to dictation were all nil but he could copy some words. His score on the Raven’s Coloured Progressive Matrices was 24/36 (Figure 3). At that time it was not possible to involve the patient in a decision about rehabilitation because he appeared not to realise how severe his deficit was and it was very difficult to make him understand what was said to him, even when he himself was the subject of the conversation. However, the family was very supportive and an aunt had plenty of time to dedicate to the patient. As for DT, he had a rather passive attitude but was always willing to do what he was asked. We therefore thought that we could rely on the family and planned a therapeutic intervention that did not require DT to work alone. He lived rather far from Milan but we decided, together with his family, that for the present time it was better to come to Milan every morning and work at home in the afternoon, as we were not convinced that a lay person could manage all the tasks we considered necessary.
  • 11. 316 BASSO AND CAPORALI September 1996 (Basso & Vignolo, 1974) TT =2/36 Rv =24/36 Downloaded By: [Universidad Michoacana de San Nicolás de Hidalgo] At: 01:13 19 September 2007 100 90 80 70 60 50 40 30 20 10 0 N V S N V S N S N S N S N S N S (n.t.) (n.t.) Oral Production Written Production Oral Written Repetition Reading Writing to Comprehen. Comprehen. aloud dictation June 1997 (Miceli et al., 1991) TT = 11/36 Rv = 29/36 100 90 80 70 60 50 40 30 20 10 0 N V S N V S N S N S N S N S N S (n.t.) Oral Production Written Production Oral Written Repetition Reading Writing to Comprehen. Comprehen. aloud dictation January 2000 (Miceli et al., 1991) TT = 19/36 (written = 31/36) Rv = 36/36 100 90 80 70 60 50 40 30 20 10 0 N V S N V S N S N S N S N S N S (n.t.) Oral Production Written Production Oral Written Repetition Reading Writing to Comprehen. Comprehen. aloud dictation TT = Token Test; RV = Raven’s Matrices; N = nouns; V = verbs; S = sentences;n.t. = not tested. Figure 3. Percentage correct responses by DT at three subsequent evaluations: September, 1996; June, 1997; January, 2000. Because almost everything the patient tried to do resulted in a failure, it was decided that the family should start with what can appear a very easy task: DT had to repeat syllables or short words, whichever was more successful. In fact this proved to be very difficult for DT and required a lot of skill and patience on the part of his aunt. After he succeeded in repeating a few words and syllables, reading and writing of syllables was introduced; mostly, however, these were accomplished by repetition and copying.
  • 12. APHASIA THERAPY 317 The therapist took on the difficult task of having DT say some content words that were Downloaded By: [Universidad Michoacana de San Nicolás de Hidalgo] At: 01:13 19 September 2007 totally absent from his speech. She could not rely on such classical facilitation as repetition or reading because DT could do neither. As for phonemic cueing it was sometimes, albeit rarely, successful but its effectiveness was very short-lived. We gave up the idea of obtaining a target content word in a convergent task, such as confrontation naming, and we tried to elicit them in more divergent and open tasks, accepting any content word DT would produce. For instance, we said a word and asked DT to say the first word that came into his mind or to complete a sentence with any word he could think of. Any content word DT said was repeated by the therapist and then included in a sentence, hoping that this would help DT become conscious of what he had said, if by chance he had produced the word automatically without really being aware of its meaning. Comprehension exercises of words and sentences such as pointing to pictures were not used. We decided that continuous verbal interactions with the therapist and his aunt would provide sufficient stimulation and we argued that this would be a more dynamic and ecological exercise. A re-evaluation 3 months later showed slight improvement in repetition and reading aloud that were now possible for some words and nonwords. Moreover, DT was now more conscious of his difficulties and he was more motivated in his rehabilitation. This allowed us to increase his homework. As he could now write some words he was also asked to do written naming at home, especially action naming, with the help of his aunt. Six months after starting rehabilitation he was again reassessed (Miceli, Laudanna, & Burani, 1991). His speech output was severely reduced and anomic; he sometimes omitted verbs and prepositions. Notwithstanding frequent omissions and phonemic paraphasias, when speaking he could make himself understood, being very good at using gestures, mime and drawings. He could name about 60% of object pictures and 30% of action pictures. Comprehension was adequate in conversation but still severely impaired on the Token Test (13/36). Repetition and reading aloud were still very severely impaired. DT had always been very keen to resume work, which he apparently could do. He was a fashion designer for a glamorous Italian fashion house. His drawing capacity was unaltered and he decided to go to work at least twice a week and come to Milan the other 3 days, working at home in the afternoons and the evenings. This regimen did not last long and he soon resumed work 5 days a week coming to Milan once every 3–4 weeks. After an initial period in which he gave up his commitment to rehabilitation because working was both tiring and very involving for DT, his homework has always been regular and intensive. Reassessed in June 1997 (Miceli et al., 1991), 15 months post-onset and 9 months after starting rehabilitation, he showed an across-the-board recovery but was still impaired in all tasks. Some peaks of impairment were evident. Reading and repetition were particularly difficult for him; he read very slowly, recognising one letter at a time. However, if given enough time he could correctly read 70% of words and 50% of short sentences. Repetition was made difficult, besides other reasons, by the fact that he had difficulties identifying heard phonemes; the contrast voiced–voiceless, for instance, was beyond his possibilities. His Token Test score was 11/36. However, his vocabulary was richer, his production more abundant but still agrammatic. His comprehension in conversation was fair, and his writing easier (Figure 3). The Appendix reports his retelling of a typical day. The same regimen was continued for the following two and a half years. Regular control examinations showed slow but continued recovery. Treatment was changed