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Absorption of-WPS Office.pptx
1. Absorption of Iron
• the iron absorb in small intestine mucosa mainly
in duodenum.
• the acidic ph of stomach favours the absorption.
• Iron is mostly found in ferris form (fe+++).
• The ferric ions are reduced by ascorbic acid and
glutathione of food to more
2. • Soluble ferrou (fe++)from wich is ir wich is more
readily absorbed
4. • The iron(fe++) entering the mucosa cell by
absorption is oxidized to ferric form by
• enzyme ferroxidase .
• the (Fe+++) combines with apoferritin to form
ferritin wich the temporary storage form of iron.
5. • From mucosa cells iron may entering the blood
stream.
• Iron enters plasma in ferrous state its oxidized
to fferric form by copper containing protein
ceruloplasimin ,ferroxidase activity.
6. • Ferric iron binds with specific iron binding
protein t( transferrin) is aglycoprotein synthesized
in liver.
• one molecules of transferrin can transport two
ferric aotms
7. • factor affecting iron absorption :
• 1_ increasing
• In effective erthropoesis
• Iron deficence
• 2_decreasing:-
• gastrointestinal deases