Overview of intravesical therapy: Current Controversies
1. Miss Jo Cresswell Consultant Urologist James Cook University Hospital, Middlesbrough Overview of Intravesical Therapy: Current Controversies
2. Overview Intravesical, Oct 2010 Intravesical Therapy Single Immediate Instillation Maintenance Chemotherapy BCG Failure T1G3
3. Single instillation of MMC: Always appropriate? Single instillation of intravesical chemotherapy Intravesical , Oct 2010
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21. Definition of failure of BCG: Intolerance – patient intolerant of side-effects BCG resistance- recurrence/persistance of lesser disease, resolves with further BCG BCG Relapsing-recurrence after initial resolution BCG Refractory-not improving or worsening with BCG Failure of intravesical treatment NMIBC, May 2010
Herr makes the point that if a recurrence is tiny and low grade can be ablated under LA, not every recurrence requires inpatent TURBT Basically according to Gudjonsson if tumour >3 on EORTC calculator – no benefit (size >3 cm, multiple, G2
Herr makes the point that if a recurrence is tiny and low grade can be ablated under LA, not every recurrence requires inpatent TURBT
Approx 500 new cases per year
Herr et al. If residual T1 on re-TUR 82% progressed over 5 years, cp to 19% without residual disease
Low grade – 3-22% Put in picture of bladderchek
Low grade – 3-22% Put in picture of bladderchek
Low grade – 3-22% Put in picture of bladderchek
Low grade – 3-22% Put in picture of bladderchek
Put in picture of ileal conduit and orthotopic neobladder
Put in bladder staging diagram again
Approx 500 new cases per year
Put in pictures/movie of blue light cystoscopy
Put in pictures/movie of blue light cystoscopy
In other words get it right first time and the effect is lasting Put in picture from BJU international
In other words get it right first time and the effect is lasting Put in picture from BJU international