Clinical Samples & Disease State Plasma Newsflash Current Biobank inventory and capabilities

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Clinical Samples & Disease State Plasma
Current Biobank Inventory & Capabilities
* Although inventory information is correct on date of publishing, many of
the materials are in high demand and stocks are limited. Custom sample
collections are possible where published inventory items are already sold.
NEWS FLASH: October 2016

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Contents
BBI Biobank – What makes our products stand out for the crowd? 3
New Products 4
Disease State Plasma Availability 5-8
Clinical Sample Availability 9-11
Depleted Serum 12-14
* Although inventory information is correct on date of publishing, many of
the materials are in high demand and stocks are limited. Custom sample
collections are possible where published inventory items are already sold.

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3
BBI BIOBANK
What makes our products stand out from the
crowd?
 Able to collect directly from Blood Banks and Hospitals
 Comprehensive characterisation
 Variety of materials available:
 Early disease phase
 Low, medium & high titres
 Rare antibodies
 Clinical data / donor demographics held for many units
 IRB / Ethical approval status for most materials
 Comprehensive and detailed CofA’s
 Operate under ISO 13485 and ISO 9001
3

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NEW PRODUCTS
NEW UNITS AVAILABLE NOW
 HCV Plasma New Units
 HBV/HCV Co-infected Units
 C Reactive Protein Positive Plasma
 Anti-Mitochondrial Antibodies Positive Plasma
 Serum Amyloid A Positive Plasma
 Glomerular Basement Membrane Antibodies Plasma
 Bilirubin Positive Plasma
 Lactate Dehydrogenase Positive Plasma
 Acetylcholine Receptor Antibodies Positive Plasma
 p-ANCA (MPO) Ab Positive Plasma
SITE UPDATES
 Heat treatment now available for
Infectious Disease
 Defibrination service available
 HIV, HBV, HCV and Syphilis SCIPAC
mixed viral load and genotype sample
panels now available
COMING SOON
 HIV-2 Serum Clinical Specimens
 NMDA Receptor Ab Positive Plasma
Place your reservation now!

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Disease State Plasma Availability
Infectious Diseases
Autoimmune/Non-Infectious Diseases
Our Capabilities
* Although inventory information is correct on date of publishing, many of
the materials are in high demand and stocks are limited. Custom sample
collections are possible where published inventory items are already sold.

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USA: 1-800-423-8199
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INFECTIOUS DISEASES
High Demand selection from current inventory:
Disease Type
Product
Code
Quantitative results & other
markers tested
Volume available in stock
HCV Plasma Units SH259-4 Viral load and antibodies 1.7L
HBV/HCV Co-infected Units SH332-4 Positive for HBV and HCV Ab >1.5L
HAV SH265 HAV IgM 3.4L
HBsAg SH256
Hep B Core Total Ab HBsAb
Viral Load, Genotype, AD/AY
11.5L
Hep B Core IgM SH258 Hep B Core IgM 4.5L
Toxoplasma IgM SH275 Toxo IgM 2.8L
CMV IgM SH272 CMV IgM 2L
Parvovirus B19 SH331 Parvovirus B19 1.5L
ToRCH Negative
Please
Enquire
Single, multiple or full ToRCH
IgG/IgM Negative
>120L
Order your evaluation sample today
Minimum order 1 unit 100ml+

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AUTOIMMUNE / NON-INFECTIOUS DISEASES
Selection from current inventory:
Disease Type Product Code
Quantitative results &
other Markers tested
Volume available in
stock (ml)
Anti-GBM SH336 Range of titres >10L
Bilirubin Positive Plasma SH294-3 Yes 2L
p-ANCA (MPO) SH152 Range of titres >20L
SAA SH127 Range of titres 20L
Thyroid Disease SH245 / SH244 Anti-Tg and Anti-TPO
Individual units or custom
pools >10L
Raised IgE High Titre SH234 Yes >10L
Lactate Dehydrogenase
Positive Plasma
SH102 Range of titres
>4L
Acetylcholine Receptor
Antibodies Pos Plasma
SH103 Yes 3L
Anti-Mitochondrial Ab SH431 Positive for M2 Ab >10L
CRP Elevated SH100 Range of titres >8L
Order you evaluation sample today
Minimum order size 100ml

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Infectious Disease Autoimmune Inflammation / Allergy
CMV IgG / IgM / Negative Anti-GBM CRP
EBV IgG / Negative Anti-RNP / Anti-SSA SAA
H. Pylori ANCA (Anti-MPO / Anti-PR3) IgE Raised Plasma
HAV Intrinsic Factor
HCV dsDNA Biochemistry
HBsAg HAMA Vitamin D
HBc IgM / Total Ab
Anti-HBs
Rheumatoid Factor
HIV-1 Anti-Tg Organ Failure / Impairment
Lyme IgG / IgM Anti-TPO Renal Failure
Malaria TRAb
HSV IgG / Negative ANA Negative Pregnancy
Rubella IgG / Negative Anti-CCP Negative Pregnancy Serum / Plasma
Synthetic Rubella IgM Anti-Voltage Gated K Channel
Syphilis Anti-Mitochondrial Ab
Toxoplasma IgG / IgM / Negative
Parvovirus
HTLV-1
ToRCH IgG / IgM Negative
Conifection HIV / HBV / HCV / Syphilis
OUR CAPABILITIES
Bulk Disease State Plasma

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Clinical Sample Availability
Infectious Disease SCIPAC Panels
Our Capabilities
* Although inventory information is correct on date of publishing, many of
the materials are in high demand and stocks are limited. Custom sample
collections are possible where published inventory items are already sold.

10. Order today sales@bbisolutions.com
Int: +44 (0) 2920 767 499
USA: 1-800-423-8199
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INFECTIOUS DISEASE SCIPAC PANELS
Panel specifications
 Citrated plasma
 Extensive donor demographics
 Tested for HIV1 & 2 Abs, HBsAg, HCV Ab, HIV-1 / HBV / HCV PCR and Syphilis
 Individual donors (no duplicates)
 Donor consent
Code no. Description Type Characteristics
SHK315-4V
HIV-1 Plasma
Panel
Mixed Viral Load
 102->600,000 Copies/ml
 9 Positive members 1 negative 2x1ml per panel
SHK256-4V
HBsAg Plasma
Panel
Mixed Viral Load
 149->600000000 IU/ml
 9 Positive members 1 negative 2x1ml per panel
SHK256-4G
HBsAg Plasma
Panel
Genotype Panel
 Genotypes A-F
 9 Positive members 1 negative 2x1ml per panel
SHK259-4V
HCV Plasma
Panel
Mixed Viral Load
 70->10000000 IU/ml
 9 Positive members 1 negative 2x1ml per panel
SHK259-4G
HCV Plasma
Panel
Genotype Panel
 Genotypes 1-6
 8 Positive members 1 negative 1x1ml per panel
SHK266-4M
Syphilis Plasma
Panel
Mixed Titre
 1:4 to 1:256 RPR
 8 Positive members 1 negative 2x1ml per panel

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Infectious Disease Autoimmune Inflammation / Allergy
CMV IgG / IgM HAMA PCT
H. Pylori Rheumatoid Factor IgE
HAV Anti-Tg CRP
HCV Anti-TPO
HBsAg Centromere Ab Biochemistry
HIV-1 Type 1 Diabetes Vitamin D
Lyme IgG Diagnosis D-Dimer
Malaria
HSV IgG / IgM Cardiac / Cardiovascular Endocrine
Malaria Troponin I/T Free T3 / T4
Rubella IgG Myoglobin PTH
Syphilis CK-MB TSH
Toxoplasma IgG / IgM NT-Pro BNP Testosterone
Parvovirus Triglycerides Progesterone
Chagas Cholesterol LH
Bilirubin Oestrogen
Organ Failure / Impairment
Cancer Renal Failure
CA125 Type 2 Diabetes
CA19-9 C-Peptide
CA15-3
AFP Pregnancy
CEA Pregnancy Serum / Plasma
Subject to Availability.
Please enquire to set up a prospective
collection.
Check out our product brochure for our
collection capabilities.
Not on this list? BBI Biobank can look to collect any
other marker of interest, just ask.OUR CAPABILITIES
Clinical Specimens

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1212
Depleted Serum
An introduction to our standard products and custom services
* Although inventory information is correct on date of publishing, many of
the materials are in high demand and stocks are limited. Custom sample
collections are possible where published inventory items are already sold.

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WHY USE OUR DEPLETED SERUMS?
“BBI have been manufacturing depleted serum for over 10 years. Our experience in this field has produced
a core range of high quality depleted serum products manufactured to ISO 9001 and ISO 13485 standards.”
Subject to lead time, volume requirement and specifications
Product Description Product Code Analyte
Typical Batch
Volume
Vitamin D SF504 Vitamin D, Vitamin D3+D2 3-60L
Immunoglobulins SF505 IgG, IgA, IgM, IgE IgD 3-15L
IgG SF142 IgG, IgA, IgM 12-25L
Steroid SF236
Progesterone, Testosterone, Cortisol,
Estradiol
12-25L
Hormones SF512
Progesterone, Testosterone, Cortisol,
Estradiol, FSH, LH, Prolactin
6L
TSH SF219
TSH (Optional Triglycerides and
Cholesterol)
6-9L
TBG SF125 TBG 12-30L
T3 / T4 SF231 T3, T4, Free T3, Free T4 3L
CRP SF100 CRP 3L
Testosterone SF518 Testosterone 3-60L
Not on this list? Check out our next slide for more
information on our custom depletion service.

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CUSTOM DEPLETION SERVICE
“BBI offers a custom depletion service to our customers
when our standard product range does not meet their
requirements. Using our many years of experience,
working with our customers on custom depletion
products, BBI will work with you to scope, source and
manufacture the product(s) you need.”
Benefits:
 Quick response time on project feasibility
 Full and comprehensive scoping process
 Raw materials required, sourced by BBI
 Can be converted into a standard product and
potentially up-scaled* with long term commitment
Matrixes Considered for Custom Depletion
 OTC Serum
 Delipidated Defibrinated Plasma
*Subject to process used and specifications.
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