This document discusses the Ayurvedic nasal procedure known as Nasya. It begins by questioning whether modern Nasya practices fully follow classical techniques. The basic anatomy of the nasal passages and their connection to the brain is then outlined. Different types of Nasya are classified and their indications, dosages, procedures, and complications are described in detail. Specific conditions that may benefit from Nasya are also explained. The document aims to analyze modern Nasya practices and promote standardizing dosage and techniques according to classical Ayurvedic texts.
Nasyakarma: The Science and Art of Nasal Administration in Ayurveda
1. Nasyakarma
Dr. Prakash Mangalasseri
Professor Dept. of Kayachikitsa, Vaidyaratnam PS Varier Ayurveda College, Kottakkal
Director, Kottakkal Ayurveda School of Excellence (KASE), an initiative of KASRS
4. Nasya
Easiest employed procedure
OPD Panchakarma
Direct entry to cranial vault
Even unconscious patient can be managed
Most popular procedure
5. Problem statement
Do we do ‘real’ Nasya?
Are complications really less?
Classical Nasya
37. Sushruta , Sharangdhara, Chakradatta???
6 Bindu each nostril x 1/2/3 times
= 12/24/36 Bindu
8 Bindu each nostril x 1/2/ 3 times
= 16/32/ 48 Bindu
10 Bindu each nostril x 1/2/3 times
= 20/40/60 Bindu
38. Routine BINDU Vs Classical BINDU
0.05ml 0.5ml
10 TIMES MORE
ONE SITTING OF NASYA
10x 1 Instillation = 10 times more
10x 2 Instillation = 20 times more
10x 3 Instillation = 30 times more
52. Contra indications (sneha nasya)
Ajeerna
After food
After drinking water
After bath
Durdina
Nava pratishyaya
During snehapana or anuvasana
58. Procedure
Sneha & sweda – uttamanga
Application of warm oil on palms & soles
Application of warm medicine (pranadi / pichu)
Mardhana of pada etc
Further sweda
2 or 3 times nasya
Dhumapana / Kabala
Diet & regimen
64. Pratimarsha nasya
Snehangulim dadyat
Dwi bindukah
Eeshath uchhringhitham dravyam yavath vakthra
prapadyate
As a Routine – 15 kala
Ubhayaarthakrith
65. Pratimarsha nasya
No age bar
No contra indication (even in akalavarsha)
No restrictions
No complications
Preferred as routine
Dushthapeenasa / Madyapeetha / Moordhni krimi /
Abalasrothra / Uthklishta dosha / Klishta dosha
84. Bioavailability
How much of the administered medication actually ends
up in the blood stream.
Examples:
IV medications are 100% bioavailable.
Most oral medications are about 5%-10% bioavailable due to
destruction in the gut and liver.
Nasal medications discussed in this lecture range in the 55% to 100%
bioavailability range - approaching IV delivery systems.
85. First pass metabolism
Molecules absorbed through the gut, including all oral
medications enter the “portal circulation” and are
transported to the liver.
Liver enzymes then break down most of these drug
molecules and only a small fraction enter the bodies
circulation as active drug.
Nasally delivered medications avoid the gut so do not
suffer first pass metabolism.
86. Nose brain pathway
The olfactory mucosa (smelling area in nose) is in direct contact with the brain
and CSF.
Medications absorbed across the olfactory mucosa directly enter the brain.
This area is termed the nose brain pathway and offers a rapid, direct route for
drug delivery to the brain.
87. Lipophilicity
“Lipid Loving.”
Cellular membranes are composed on layers of lipid material.
Drugs that are lipophilic are easily and rapidly absorbed across the
mucous membranes.
88. Intranasal Medication -Absrption
Drugs absorbed via the nasal mucosa:
Are absorbed via the rich vascular plexus of the nose and
directly enter the circulation.
Can be absorbed directly through the olfactory mucosa into
the CSF - giving rapid brain levels of the drug.
89. Intranasal Medication Administration:
Advantages
Compared to oral medications, intranasal medication delivery results in:
Faster delivery to the blood stream
Higher blood levels
No destruction by stomach acid and intestinal
enzymes
No destruction by hepatic first pass metabolism