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Spontaneous
OsteoNecrosis of
Knee (SONK)
(Ahlback's disease)
Dr.Avik Sarkar
KB Bhabha Municipal General Hospital, Bandra (West), Mumbai
• Spontaneous Osteonecrosis of the
Knee, also known as Ahlback's
disease is the result of vascular arterial
insufficiency to the medial femoral
condyle of the knee resulting
in necrosis and destruction of bone
INCIDENCE
• Elderly Women are generally affected
[seen more frequently in women (M:F = 1:3)
and typically over the age of 55]
RISK FACTORS (POSSIBLE)
• Corticosteroid use
• Systemic Lupus Erythematosus (SLE)
• Alcoholism
• Pancreatitis
• Sickle Cell disease
• Rheumatoid Arthritis
• Caisson disease
• Gaucher disease
SITE / LOCATION
• 99% of patients have only one joint
involved
• usually epiphysis of medial femoral
condyle is involved
PATHOPHYSIOLOGY
• Osteonecrosis in SONK has no
predisposing factors.
• Speculations include
-subchondral insufficiency fracture
-may be caused by a meniscal root tear
PRESENTATION / SYMPTOMS
• sudden onset of severe knee pain, increased
at night and with activity
• effusion
• limited range of motion secondary to pain
• tenderness over medial femoral condyle
IMAGING
• X-Ray
• Technetium-99m scan
• MRI
X-Ray
• Standing AP view
• Standing Lateral view
• Tunnel view (long axis of femur at 600
to long axis of
tibia)
• Initially, no abnormalities may be seen,
but as the disease progresses,
flattening of the weight-bearing portion
may occur.
• A radiolucent area forms in the subchondral
bone, surrounded by a rim of sclerosis.
Later in the disease course, the subchondral
bone collapses, leading to secondary arthritic
change and varus deformity.
Technetium-99m scans
• Show a localized area of radioisotope uptake in
the medial femoral condyle.
• Bone Scans provide a correct diagnosis in only
40-70% of cases
• Less effective for diagnosing secondary
osteonecrosis than for diagnosing SONK
MRI
• On T1-weighted images, osteonecrosis is seen as a discrete area of low
signal intensity, replacing the high-intensity signal normally produced by
marrow fat.
• The T2-weighted image shows an area of low signal intensity surrounded
by a high-intensity signal caused by edema.
• Specificity and Sensitivity of MRI are 98% in SONK, hence MRI is the
diagnostic study of choice.
STAGING
• Aglietti devised the following classification system which
is a modification of an earlier classification by Koshino:
• Stage I: Plain radiograph findings are normal. Diagnosis
must be made from MRI or bone scan.
• Stage II: Radiographs show flattening of the
weightbearing portion of the condyle
• Stage III: Radiographs show a radiolucent area
surrounded by sclerosis
• Stage IV: Radiographs show a more defined ring of
sclerosis and subchondral bone collapse forming a
calcified plate, sequestrum, or fragment
• Stage V: Narrowing of the joint space, osteophyte
formation, and/or femoral and tibial subchondral
sclerosis is shown
TREATMENT
NON-SURGICAL /
CONSERVATIVE
• In the early stages of the disease, treatment is not
surgical. Treatment include-
• Medications to reduce the pain (NSAIDS)
• A brace to relieve pressure on the joint surface
• A conditioning program with exercises to strengthen
quadriceps and hamstring muscles
• Lifestyle & Activity modifications to reduce knee pain
TREATMENT
SURGICAL
• If more than half of the bone surface is
affected, surgical treatment may be
considered. Options are
• Arthroscopic debridement
• Osteochondral grafts
• High Tibial Osteotomy (HTO)
• Core decompression
• Unicondylar Knee Arthroplasty
• Total Knee Arthroplasty
Arthroscopy
• For debridement of degenerative tears in
the menisci.
• Mixed results as it may cause further
degeneration of the knee joint and
possibility of increased interosseous
pressure.
Osteochondral Graft
• Both allograft and autografts have been
used with discouraging results
High Tibial Osteotomy (HTO)
• High tibial osteotomy (HTO) has been
used in patients of SONK, with
encouraging results.
Core Decompression
• The principle is to reduce interosseous
pressure, thereby restoring adequate
circulation.
• Some success have been observed in the
earlier stages of osteonecrosis.
Unicondylar Arthroplasty
• Unicondylar arthroplasty
has been used with success,
as the disease usually is
confined to one condyle
Total Knee Arthroplasty
• Knee arthroplasty is indicated in the late
stages of the disease. Indications are -
• degenerative changes
• severe pain
• functional disability
PROGNOSIS
• Aglietti et al reported that lesions greater
than 5 cm2
had a worse prognosis than
lesions with areas less than 3.5
cm2
. Hence, prognosis of SONK is directly
related to the size of the lesion.
DIFFERENTIAL DIAGNOSIS
• Osteochondritis Dissecans
– more common on lateral aspect of medial
femoral condyle in adolescent males
• Transient Osteoporosis
– more common in young to middle age men
• Bone Bruises and Occult Fractures
– associated trauma, bone fragility or overuse
• Idiopathic Osteonecrosis of the Knee
– lesion is not crescent shaped

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Spontaneous OsteoNecrosis of Knee (SONK)

  • 1. Spontaneous OsteoNecrosis of Knee (SONK) (Ahlback's disease) Dr.Avik Sarkar KB Bhabha Municipal General Hospital, Bandra (West), Mumbai
  • 2. • Spontaneous Osteonecrosis of the Knee, also known as Ahlback's disease is the result of vascular arterial insufficiency to the medial femoral condyle of the knee resulting in necrosis and destruction of bone
  • 3. INCIDENCE • Elderly Women are generally affected [seen more frequently in women (M:F = 1:3) and typically over the age of 55]
  • 4. RISK FACTORS (POSSIBLE) • Corticosteroid use • Systemic Lupus Erythematosus (SLE) • Alcoholism • Pancreatitis • Sickle Cell disease • Rheumatoid Arthritis • Caisson disease • Gaucher disease
  • 5. SITE / LOCATION • 99% of patients have only one joint involved • usually epiphysis of medial femoral condyle is involved
  • 6. PATHOPHYSIOLOGY • Osteonecrosis in SONK has no predisposing factors. • Speculations include -subchondral insufficiency fracture -may be caused by a meniscal root tear
  • 7. PRESENTATION / SYMPTOMS • sudden onset of severe knee pain, increased at night and with activity • effusion • limited range of motion secondary to pain • tenderness over medial femoral condyle
  • 9. X-Ray • Standing AP view • Standing Lateral view • Tunnel view (long axis of femur at 600 to long axis of tibia) • Initially, no abnormalities may be seen, but as the disease progresses, flattening of the weight-bearing portion may occur. • A radiolucent area forms in the subchondral bone, surrounded by a rim of sclerosis. Later in the disease course, the subchondral bone collapses, leading to secondary arthritic change and varus deformity.
  • 10. Technetium-99m scans • Show a localized area of radioisotope uptake in the medial femoral condyle. • Bone Scans provide a correct diagnosis in only 40-70% of cases • Less effective for diagnosing secondary osteonecrosis than for diagnosing SONK
  • 11. MRI • On T1-weighted images, osteonecrosis is seen as a discrete area of low signal intensity, replacing the high-intensity signal normally produced by marrow fat. • The T2-weighted image shows an area of low signal intensity surrounded by a high-intensity signal caused by edema. • Specificity and Sensitivity of MRI are 98% in SONK, hence MRI is the diagnostic study of choice.
  • 12. STAGING • Aglietti devised the following classification system which is a modification of an earlier classification by Koshino: • Stage I: Plain radiograph findings are normal. Diagnosis must be made from MRI or bone scan. • Stage II: Radiographs show flattening of the weightbearing portion of the condyle • Stage III: Radiographs show a radiolucent area surrounded by sclerosis • Stage IV: Radiographs show a more defined ring of sclerosis and subchondral bone collapse forming a calcified plate, sequestrum, or fragment • Stage V: Narrowing of the joint space, osteophyte formation, and/or femoral and tibial subchondral sclerosis is shown
  • 13. TREATMENT NON-SURGICAL / CONSERVATIVE • In the early stages of the disease, treatment is not surgical. Treatment include- • Medications to reduce the pain (NSAIDS) • A brace to relieve pressure on the joint surface • A conditioning program with exercises to strengthen quadriceps and hamstring muscles • Lifestyle & Activity modifications to reduce knee pain
  • 14. TREATMENT SURGICAL • If more than half of the bone surface is affected, surgical treatment may be considered. Options are • Arthroscopic debridement • Osteochondral grafts • High Tibial Osteotomy (HTO) • Core decompression • Unicondylar Knee Arthroplasty • Total Knee Arthroplasty
  • 15. Arthroscopy • For debridement of degenerative tears in the menisci. • Mixed results as it may cause further degeneration of the knee joint and possibility of increased interosseous pressure.
  • 16. Osteochondral Graft • Both allograft and autografts have been used with discouraging results
  • 17. High Tibial Osteotomy (HTO) • High tibial osteotomy (HTO) has been used in patients of SONK, with encouraging results.
  • 18. Core Decompression • The principle is to reduce interosseous pressure, thereby restoring adequate circulation. • Some success have been observed in the earlier stages of osteonecrosis.
  • 19. Unicondylar Arthroplasty • Unicondylar arthroplasty has been used with success, as the disease usually is confined to one condyle
  • 20. Total Knee Arthroplasty • Knee arthroplasty is indicated in the late stages of the disease. Indications are - • degenerative changes • severe pain • functional disability
  • 21. PROGNOSIS • Aglietti et al reported that lesions greater than 5 cm2 had a worse prognosis than lesions with areas less than 3.5 cm2 . Hence, prognosis of SONK is directly related to the size of the lesion.
  • 22. DIFFERENTIAL DIAGNOSIS • Osteochondritis Dissecans – more common on lateral aspect of medial femoral condyle in adolescent males • Transient Osteoporosis – more common in young to middle age men • Bone Bruises and Occult Fractures – associated trauma, bone fragility or overuse • Idiopathic Osteonecrosis of the Knee – lesion is not crescent shaped