This document provides definitions and classifications related to the field of pharmacology. It defines pharmacology as the study of drugs and their actions in the body. Key topics covered include the definitions of pharmacokinetics, pharmacodynamics, pharmacoepidemiology, pharmacoeconomics, pharmacogenomics, toxicology, pharmacovigilance, therapeutics, clinical pharmacology, receptors, ligands, potency, and tolerance. It also discusses sources of drug information like pharmacopeias and the expanding scope of pharmacology to incorporate new approaches like computer-assisted drug design and novel drug delivery methods.
3. The term drug is originated from the french word
DROGUE Meaning a dry herb.
The WHO defined “ DRUG AS A SUBSTANCE OR
PRODUCT THAT IS USED FOR THE PURPOSE OF
DIAGNOSIS,PREVENTION,RELIEF OR CURE OF A DISEASE
IN MANAND ANIMAL”
Pharmacolog is the studyof Drug and its Action
7. DEFINITIONS
Pharmacokinetics: pharmacokinetics its
greek word kinesis means movement.In simple term
means The action of body on the drug.
Pharmacokinetics includes the study of drug Absorption,
Distribution,Metabolism and Excreation.
Pharmacodynamics:
pharmacodynamics its greek word dynamics means
power.That explain the mechanism in which a drug acts and
correlate with the actionof the drug.
8. Pharmacoepidemiology:Pharmac
ology involve the study of utilisation of drug
and its effect on a large population.
Pharmacoeconomics:Pharmacoec
onomics involve the scientific studiesof
a drug or drug therapy.
Pharmacogenomics:pharmacogen
omics is a study that involve the effect
of the genetic structure of an individual
on drug response.
9. Toxicology: The study of adverse effect of
chemical on living organism its termed as
Toxicology.It includes thestudy of symptoms,mode
of action,treatments and detection of poisoning .
Pharmacovigilance : It is the part of
pharamcoepidemiology that involves the study of
pharmacokinetic and pharmacodynamics features
of adrug which is already present in the market.
Therapeutics: Therapeutics is the art and
science of healing ,dealing with the treatment of
diseases and infection conditions.
10. Clinical pharmacology: Clinical
pharmacology includes the scientific study of
drug on clinical resources.
Receptors: Receptor are macromolecules
present on the cell surface ; the drug molecules
bind to these receptor resulting in the modulation
of thier functions.
Ligands: Substance that bind to receptor are
known as ligands.
Potency: Potency is the amount or
concentration of dose needed to produce desired
effect of a given entity.
11. Tolerance: Tolerance is the decreased of
an organism to respond to repeated
administration of drug.
Side effect: These are effect of drug other
than the therapeutic effect. Harmful side effect
of any therapeutic substance are known as
adverse drug reaction.
12. Sources of Drug information
The sources of drug information is received by
pharmacopeia that is a book which contain a list of
estabilished and officially approved drug with description
of their physical and chemical characteristic and tests for
their identification,purity,methods of storage etc.some of
the pharmacopeias are
Indain pharmacopeia (I.P)
British pharmacopeia (B.P)
European pharmacopeia (E.P)
United state pharmacopeia (U.S.P)
13. Scope of pharmacology
Scintific understanding of drug enables us to predict the
pharmacological effect of a new chemical that will produce
a specific therapeutic effect.
The scope of pharmacology has expanded greatly over the
last decade to incorporate many new approaches such as
computer-assisted drug design,genetic screens ,protection
engineering and use of novel drug delivey vehicle including
viruses and artificial cells.
Our society needs pharmacologists who understand the
basis of modern therapeutic for career within academic
,pharmaceutical and govermental laboratories to study and
develop tommows drugs.