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Airway management in
critical illness
ARUN RADHAKRISHNAN
Case
50/M with bad CAP
SpO2 70% on 4 L NP
RR 40, HR 120, BP 100/70, Temperature 39o C
Agitated, not accepting mask
How are you going to intubate this guy?
Why is intubation
required? 8 P’s
Airway protection
Maintain airway patency
To provide higher PEEP
High FiO2 requirements (Purified O2)
Pulmonary toileting
Reduce WOB (Power-up breathing)
Anticipated need for unusual
positioning (e.g., prone ventilation)
Facilitate procedures/investigations
What are the goals of
airway management?
Goals of airway management
Achieving ‘First-pass’ success
Keeping the patient safe
◦ Preventing Hypoxaemia
◦ Preventing Hypotension
Introduction
Why is airway management very different in ICU as
compared to the OT?
◦ Suboptimal conditions
◦ Limited physiologic reserve
◦ Practitioners with variable levels of experience
◦ Time
Situations
where the
airway may be
difficult?
Head and neck trauma
Known airway &/or C spine pathology
Morbid obesity or pregnancy
Burns affecting airway
Do you know of any scoring systems?
The
‘Physiologically
Difficult’ airway
Hypoxaemia Hypotension
Severe
metabolic
acidosis
RV failure
Definitions
Impossible Mask Ventilation:
Absence of ETCO2, no chest
wall movement during positive
pressure ventilation despite
airway adjuvants and additional
personnel
Difficult Intubation: Multiple
attempts required, in the
presence or absence of tracheal
pathology
Difficult Laryngoscopy: Not
possible to visualize any portion
of the vocal cords after multiple
attempts at conventional
laryngoscopy ( Cormack-Lehane
grade 3 or 4 view)
Where can things go wrong?
At all stages!
Airway assessment
Patient selection and preparation
Human and team factors
Selection of technique and equipment
Haemodynamic management
Post-intubation management
Hence the term ‘Airway Management’ as opposed to
‘Intubation’!
Airway management
Airway
Management
Patient‘s
Airway
assessment
Operator
experience and
resources
available
Haemodynamic and
respiratory stability
Patient preparation and
optimization
Post-intubation care
Team management
Pitfalls
Failure to plan
Positioning and preparation
Pre-oxygenation
Haemodynamic management
Equipment
Surgical airway
Post-intubation management
How do we approach the critical
airway?
Preparation, more
preparation,
communication, planning
for all eventualities
Strategies to avoid
intubation in the first
place ?!
Airway assessment
Don’t forget…
Feel and mark the Cricothyroid membrane
Considering the need for FONA is crucial in all patients!
What can be optimised?
Achieving safety-Preparation
Optimize Patient physiology
◦ Positioning
◦ Oxygenation
◦ Haemodynamics
Monitoring
Resources-identify and allocate
Prepare the team- communication
Achieving safety
Secure IV Access
Drugs for emergencies –
◦ Atropine, Adrenaline, Metaraminol
◦ Norad, metaraminol infusions
Routine medications
◦ Dosing considerations
Fluid bolus
Monitoring
SpO2
ETCO2
ECG
BP
Achieving
safety-
Equipment
Remember the acronym
MALES/MEALS
M Mask
A Airway
L Laryngoscope
E ETT
S Suction
Equipment considerations
Laryngoscopes of various sizes and types
◦ Video laryngoscopes increasingly used
Stylets and bougies
Airway exchange catheters
ETTs of 1 size larger and smaller than anticipated
Rescue equipment
◦ SGA
◦ FOB
◦ Cricothyroidotomy set
Safety
CHECKLIST DIFFICULT AIRWAY TROLLEY
The team…
TEAM MANAGEMENT
Communicate plan A/B/C clearly
Advantages?
Ensure backup resources available
Induction techniques
Rapid sequence (RSI)
Graded Sedation Intubation (GSI)
Delayed sequence (DSI)
Awake intubation
RSI
Rapid push of IV agents (Anaesthetic and paralytic)
simultaneously to facilitate rapid securing of the
airway
Increases potential for surprises – difficulty with
intubation
Preparation is key
Do you ventilate the patient?
What are the problems
with RSI?
Delayed Sequence induction
Procedural sedation, the procedure being…preoxygenation
Position, preoxygenate
Ketamine 1-2 mg/kg IV slow, use more if required
Nasal cannulae O2 @ 15 Lpm
Preoxygenate with BVM + PEEP Valve or NRB, at least 3 min
Administer NMB
Intubate
Graded Sedation Intubation (GSI)
Both GSI and DSI aim to prioritize oxygenation and patient safety over rapid intubation
GSI doesn’t involve paralysis whereas DSI does
Induction/anaesthetic agents used may differ
Awake intubation
Best left to the anaesthetist ?!!!
Patient selection
Indications & advantages?
Anything
missing
so far?
Team
management
Skilled
assistance
Plan B/C/D
Post-
intubation
management
Patient positioning
Keep patient as upright as possible until
intubation
Continue NIV
Best position to intubate:
◦ Classic ‘ Sniffing’ position
◦ Ear (EAM) in same plane as sternal notch (Ramp
position)
Why is
positioning
important?
Alignment of all
axes
Pt comfort
Prevents de-
recruitment of
basal lung regions
Degree of
protection from
hypoxaemia
Preoxygenation
Why is this important?
How do we do it?
What are the processes involved?
Preoxygenation Vs. Denitrogenation
Denitrogenation – replacement of nitrogen (in lungs) with oxygen
Oxygenation- providing best possible conditions to withstand intubation process
◦ NIV- do not discontinue
◦ Supplemental Oxygenation- NPs/HFNPs
◦ Which one technique is superior (NIV Vs. O2 insufflation)?
Pre-oxygenation
3 minutes, or 8 VC breaths with tight-fitting mask at
100% O2
Difficult to achieve
What sats do you aim for pre-intubation?
Peroxygenation…???
Peri-intubation oxygenation
◦ NPs at 15 Lpm
◦ CPAP (5-10 cm H2O)
◦ Apnoiec oxygenation
◦ Transnasal humidified rapid insufflation ventilator exchange (THRIVE) – HFNPs @ 70 Lpm
◦ Oxygenation during mask ventilation (BMV)
◦ NIV
What are we trying to do?
Prolong the ‘Safe Apnoea’ time
How does O2 insufflation help during apnoea?
Other methods – the triple 15 rule
Nasal prongs with 15 Lpm flow
NRB mask with 15 Lpm flow
And, if SpO2 still less than 95%,
NIV or BVM with PEEP of 15 cm H2O
https://www.jems.com/articles/print/volume-43/issue-4/features/a-modern-approach-to-basic-airway-management.html?c=1
Haemodynamic
preparation
Secure IV access
Preload – fluid bolus
Vasopressors already commenced, and push pressors
available
Aim for a SBP of > 100 - 120 or MAP around 70-80 prior
to induction
Complications
peri-intubation
Hypoxaemia
Aspiration
Airway trauma
Cardiovascular instability
Optimization
Unable to intubate- what next???
Plans B,C and D
Various algorithms
Call out ‘Difficult Intubation’
Attempt Oxygenation
◦ BMV
◦ SGA
Do not make more than 3 attempts-why?
Unable
to
intubate-
what
next???
Protect oxygenation
BMV ventilation (if
patient sedated and
paralyzed) or allow
spontaneous breathing
Next steps depend on
Ability to oxygenate
Availability of skilled
help
Unable to
intubate-
Supraglottic
airway
Logical next step- rescue
oxygenation
LMAs and other devices
Can facilitate Fibreoptic
intubation
Unable to intubate or oxygenate- what
next???
Call out ‘Can’t Intubate Can’t Oxygenate’ (CICO)
Prepare for Surgical airway
Thinking about it beforehand is the first step
◦ https://youtu.be/RrIzIxoshMg
Achieving safety - Checklists
Have you seen them being used?
Difficult Airway Society guidelines
https://www.das.uk.com/guidelines/icu_guidelines2017
Post-intubation
Do not walk away!!!!
Confirm ETT placement
Manage haemodynamics
Plan for ventilation, sedation, analgesia etc.
Potential issues post-intubation?
Recap
Avoid common pitfalls
Prepare for the difficult airway
Positioning, Preoxygenation, Physiologic optimization, Planning
Team approach
Coming back to the case…
What do you do?
Can we summarize what we have learnt today?
Difficult intubation scenarios…
H&N trauma
Airway burns
Anaphylaxis
Pregnancy
Morbid obesity
Cervical spine pathology
Upper airway obstruction
Paediatric
Unplanned extubation
The end
Failing to plan is planning to
fail!
References (in no particular order)
1. Umobong and Mayo. Crit Care Clin 34 (2018) 313–324
2. De Jong et al. Critical Care 2014, 18:209 (http://ccforum.com/content/18/2/209)
3. Griesdale et al. Lung 2011, DOI 10.1007/s00408-011-9278-3
4. Higgs et al. British Journal of Anaesthesia, 120 (2): 323-352 (2018)
5. Difficult airway society guidelines. https://das.uk.com/guidelines/icu_guidelines2017
6. Vortexapproach.org
7. https://lifeinthefastlane.com/ccc/airway-assessment/
8. Myatra SN et al. Indian J Anaesth 2016;60:885-98

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