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CARDIAC
PHYSIOLOGY
& ANAESTHETIC
CONSIDERATIONS
By- Dr. Armaan Singh
Heart
Hollow
Located within the mediastinum of the thorax
Distal end extends downward to the left forming apex at the
fifth intercostal space.
By-Dr.ArmaanSingh
HEART STRUCTURE
ANATOMICALLY ONE ORGAN
FUNCTIONALLY DIVIDE INTO RT. & LT PUMPS
FOUR VALVES WITH UNIDIRECTIONAL FLOW
By-Dr.ArmaanSingh
By-Dr.ArmaanSingh
By-Dr.ArmaanSingh
Pulmonary
and
Systemic
Bloodflow
By-Dr.ArmaanSingh
The heart consists of three different layers
By-Dr.ArmaanSingh
Coronary supply
Inferior Rt coronary
Anteroseptal Lt ant descening
Anteroapical Lt ant
desceding( distal)
Anterolateral Circumflex
Posterior Rt coronary artery
By- Dr. Armaan Singh
CARDIAC ACTION POTENTIAL
l
By-Dr.ArmaanSingh
By-Dr.ArmaanSingh
MEMBRANEPOTENTIAL(mV)
-90
0
0
1
2
3
4
TIME
PHASE
0 = Rapid Depolarization
(inward Na+
current)
1 = Overshoot
2 = Plateau
(inward Ca++
current)
3 = Repolarization
(outward K+
current)
4 = Resting Potential
Mechanical Response
PACEMAKERS (in order of
their inherent rhythm)
• Sino-atrial (SA) node
• Atrio-ventricular (AV) node
• Bundle of His
• Bundle branches
• Purkinje fibers
By-Dr.ArmaanSingh
By-Dr.ArmaanSingh
AtrioVentricular Node
Sinoatrial Node
Atrioventricular Bundle
Purkinje Fibers
Heart Conduction System
INITIATION & CONDUCTION OF THE
CARDIAC IMPULSE
By-Dr.ArmaanSingh
Heart Actions
• Atrial systole is when the atria contract while the ventricles
relax which is called ventricular diastole.
• Thus systolic and diastolic blood pressure.
• This series of contraction and relaxation is called a cardiac
cycle.
By-Dr.ArmaanSingh
By-Dr.ArmaanSingh
LATE DIASTOLE
ATRIAL
SYSTOLE
ISOMETRIC VENTRICULAR
CONTRACTION
VENTRICULAR
EJECTION
ISOMETRIC
VENTRICULAR
RELAXATION
EVENTS IN CARDIAC
CYCLE
DIASTOLE
CARDIAC CYCLE
By-Dr.ArmaanSingh
Atrial
Systole
Mitral
Closes
Isovolumiccontract.
Aortic
opens
S1
RapidEjection
ReducedEjection
IsovolumicRelax.
Aortic
closes
RapidVentricular
Filling
Mitral
opens
S2
ReducedVentricular
Filling
Atrial
Systole
CARDIAC OUTPUT
• DEFIND AS VOLUME OF BLOOD PUMPED BY HEART/MIN
• CO = SV X HR
• SV IS VOLUME PUMPED PER CONTRACTION
• average cardiac output would be 5L.min-1 for a human male
and 4.5L.min-1 for a female.
By-Dr.ArmaanSingh
CARDIAC OUTPUT AND THE FICK
PRINCIPLE
By-Dr.ArmaanSingh
BODY O2 CONSUMPTION
250mlO2/min
PaO2
190mlO2/l blood
PvO2
140mlO2/l blood
PULMONARY
ARTERY
PULMONARY
VEIN
CARDIAC OUTPUT=
O2 CONSUMPTION (ml/min)
PaO2
- PvO2
Pulmonary capillaries
Lungs
Pulse
• Pressure wave move along the artery wall
which are pliable
• usually measured in beats per minute
• normal range from 60 to 100 beats per minute
By-Dr.ArmaanSingh
Factors Influencing the Pulse
• Stroke volume
• Rate of ejection
• Distensibility of peripheral arteries
• Peripheral resistance
• Pulse rate
• Pulse pressure
• Size of the vessel
• Distance from the heart
By-Dr.ArmaanSingh
Pulsus Parvus
• The pressure is diminished, and the pulse feels weak and small,
seen in - restrictive pericardial disease, hypovolemia, mitral stenosis
• Pulsus Parvus et Tardus (weak and delayed):
→Aortic Stenosis
By-Dr.ArmaanSingh
Bisferiens Pulse
• Increased arterial pulse with a double systolic peak.
• Causes : AR
• HCM
By-Dr.ArmaanSingh
Bigeminal Pulse
• characterized by groups of two heartbeats close together followed
by a longer pause. The second pulse is weaker than the first
• Causes: severe HF, hypovolemic shock, cardiac tamponade)
By-Dr.ArmaanSingh
Pulsus Alternans
arterial pulse waveform showing alternating strong and weak
beats
• Causes:
• Left ventricular failure
• severe AR
By-Dr.ArmaanSingh
Pulsus Paradoxus
• Pressure drop > 20 mmHg during inspiration.
• Normally, systolic arterial pressure falls 8-12 mmHg during
inspiration.
• Causes:
• Cardiac Tamponade
• COPD, hypovolemic shock
By-Dr.ArmaanSingh
BLOOD PRESSURE
• DEFINE AS PRESSURE OF BLOOD AGAINST THE WALL OF MAIN
ARTRIES
• HIGHEST DURING SYSTOLE N LOWEST DURING DIASTOLE
• MEASURED BY SPHYGMOMANOMETER @ BRACHIAL ARTERY
OF ARM
By-Dr.ArmaanSingh
Blood Pressure (BP):
Measurements
By-Dr.ArmaanSingh
Figure 15-7: Measurement of arterial blood pressure
CLASSIFICATION
Category Systolic Diastolic
hypotension <90 <60
normal 90 – 119 60 - 79
prehypertes
ion
120 - 139 80 - 89
stage1ht 140 - 159 90 - 99
stage2ht >160 >100
By- Dr. Armaan Singh
Pulse and Mean Arterial Pressures
• Pulse pressure = Systolic –Diastolic
• Mean arterial pressure (MAP) = Diastolic +
1/3 pulse pressure
By-Dr.ArmaanSingh
By-Dr.ArmaanSingh
By-Dr.ArmaanSingh
By-Dr.ArmaanSingh
EJECTION FRACTION
• Ejection fraction (Ef) is the fraction of the end-diastolic
volume that is ejected with each beat
• it is stroke volume (SV) divided by end-diastolic volume (EDV):
By-Dr.ArmaanSingh
EJECTION FRACTION
• In a healthy man, the SV is approximately 70 ml and the left
ventricular EDV is 120 ml, giving an ejection fraction of
70/120, or 0.58 (58%).
• Healthy individuals typically have ejection fractions between
50% and 65%
By-Dr.ArmaanSingh
METHODS OF EF MEASUREMENT
• CARDIAC CATHETRISATION
• RADIONUCLEOTIDE STUDIES
• ANGIOCARDIOGRAPHY
By-Dr.ArmaanSingh
CARDIAC INDEX
• Cardiac index (CI) is a vasodynamic parameter that relates the
cardiac output to body surface area
• unit of measurement is (l/min/m2)
• normal range of cardiac index is 2.6 - 4.2 L/min per square meter.
By-Dr.ArmaanSingh
ANAESTHETIC
CONSIDERATION• Halothaane isoflurane and enflurane depress SA node
automaticity.
• IV induction agent have limited effect on usual clinical doses.
• Opioids can depress cardiac conduction.
• LA associated with systemic toxicity.
By-Dr.ArmaanSingh
GOALS OF ANAESTHESIA IN CVS
DISEASES
• PREMEDICATE BY BZP’S
• BLUNT RESPONSE BY LARYGOSCOPY N INTUBATION
• AVOID TACHYCARDIA
• AVOID HYPOCAPNIA
By-Dr.ArmaanSingh
THANK YOU
By-Dr.ArmaanSingh
By-Dr.ArmaanSingh
FOR MORE MEDICAL PRESENTATIONS VISIT
Slideshare/Dr. Armaan Singh

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Cardiacphysiology&anaestheticconsiderationscardiacoutput,pulse,bp,cardiacindex,coronarycirculation

Hinweis der Redaktion

  1. Features of the heart especially the systemic and pulmonary blood vessels chambers and valves.