2. Heart
Hollow
Located within the mediastinum of the thorax
Distal end extends downward to the left forming apex at the
fifth intercostal space.
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3. HEART STRUCTURE
ANATOMICALLY ONE ORGAN
FUNCTIONALLY DIVIDE INTO RT. & LT PUMPS
FOUR VALVES WITH UNIDIRECTIONAL FLOW
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11. PACEMAKERS (in order of
their inherent rhythm)
• Sino-atrial (SA) node
• Atrio-ventricular (AV) node
• Bundle of His
• Bundle branches
• Purkinje fibers
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14. Heart Actions
• Atrial systole is when the atria contract while the ventricles
relax which is called ventricular diastole.
• Thus systolic and diastolic blood pressure.
• This series of contraction and relaxation is called a cardiac
cycle.
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17. CARDIAC OUTPUT
• DEFIND AS VOLUME OF BLOOD PUMPED BY HEART/MIN
• CO = SV X HR
• SV IS VOLUME PUMPED PER CONTRACTION
• average cardiac output would be 5L.min-1 for a human male
and 4.5L.min-1 for a female.
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18. CARDIAC OUTPUT AND THE FICK
PRINCIPLE
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BODY O2 CONSUMPTION
250mlO2/min
PaO2
190mlO2/l blood
PvO2
140mlO2/l blood
PULMONARY
ARTERY
PULMONARY
VEIN
CARDIAC OUTPUT=
O2 CONSUMPTION (ml/min)
PaO2
- PvO2
Pulmonary capillaries
Lungs
19. Pulse
• Pressure wave move along the artery wall
which are pliable
• usually measured in beats per minute
• normal range from 60 to 100 beats per minute
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20. Factors Influencing the Pulse
• Stroke volume
• Rate of ejection
• Distensibility of peripheral arteries
• Peripheral resistance
• Pulse rate
• Pulse pressure
• Size of the vessel
• Distance from the heart
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21. Pulsus Parvus
• The pressure is diminished, and the pulse feels weak and small,
seen in - restrictive pericardial disease, hypovolemia, mitral stenosis
• Pulsus Parvus et Tardus (weak and delayed):
→Aortic Stenosis
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23. Bigeminal Pulse
• characterized by groups of two heartbeats close together followed
by a longer pause. The second pulse is weaker than the first
• Causes: severe HF, hypovolemic shock, cardiac tamponade)
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24. Pulsus Alternans
arterial pulse waveform showing alternating strong and weak
beats
• Causes:
• Left ventricular failure
• severe AR
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26. BLOOD PRESSURE
• DEFINE AS PRESSURE OF BLOOD AGAINST THE WALL OF MAIN
ARTRIES
• HIGHEST DURING SYSTOLE N LOWEST DURING DIASTOLE
• MEASURED BY SPHYGMOMANOMETER @ BRACHIAL ARTERY
OF ARM
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33. EJECTION FRACTION
• Ejection fraction (Ef) is the fraction of the end-diastolic
volume that is ejected with each beat
• it is stroke volume (SV) divided by end-diastolic volume (EDV):
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34. EJECTION FRACTION
• In a healthy man, the SV is approximately 70 ml and the left
ventricular EDV is 120 ml, giving an ejection fraction of
70/120, or 0.58 (58%).
• Healthy individuals typically have ejection fractions between
50% and 65%
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35. METHODS OF EF MEASUREMENT
• CARDIAC CATHETRISATION
• RADIONUCLEOTIDE STUDIES
• ANGIOCARDIOGRAPHY
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36. CARDIAC INDEX
• Cardiac index (CI) is a vasodynamic parameter that relates the
cardiac output to body surface area
• unit of measurement is (l/min/m2)
• normal range of cardiac index is 2.6 - 4.2 L/min per square meter.
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37. ANAESTHETIC
CONSIDERATION• Halothaane isoflurane and enflurane depress SA node
automaticity.
• IV induction agent have limited effect on usual clinical doses.
• Opioids can depress cardiac conduction.
• LA associated with systemic toxicity.
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38. GOALS OF ANAESTHESIA IN CVS
DISEASES
• PREMEDICATE BY BZP’S
• BLUNT RESPONSE BY LARYGOSCOPY N INTUBATION
• AVOID TACHYCARDIA
• AVOID HYPOCAPNIA
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