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Contrast Agent in Angiography M. Fathi ;Bs Medical Imaging- TUMS October 2011- Kerman
Selection of contrast media
Aspects of importance with regard to CIN include:  ,[object Object],[object Object],[object Object],[object Object]
Route of administration  ,[object Object],[object Object]
Intra-arterial  administration delivers a higher concentration of CM to the kidney is true only for studies performed above the renal arteries.
[object Object],[object Object]
Greater volume of CM often administered in  intra-arterial  studies, particularly when diagnostic studies are combined with interventions.
VOLUME OF CM ,[object Object],[object Object],[object Object],[object Object]
Specific of the CM ,[object Object],[object Object],[object Object]
[object Object],[object Object],Meta-regression analysis of the available data on the incidence of CIN following  intra-arterial  administration of low- or iso-osmolality CM suggests that the osmolality of the contrast agent alone does not account for the differences in the adverse reactions. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Witch one? ,[object Object],[object Object],[object Object]
Contrast Media Specifications ACR Manual on Contrast Media Product Chemical structure % Salt Concentration % Iodine Concentration Iodine + (mg/ml) Viscosity 37 (cps) Osmolality (mOsm/kg)  Iohexol 240 Nonionic None 24 240 3.4 520 Iopromide 240 Nonionic <0.1 24 240 2.8 483 Iohexol 300 Nonionic None 30 300 6.3 672 Iopromide 300 Nonionic <0.1 30 300 4.9 607 Iohexol 350 Nonionic None 35 350 10.4 844 Iopromide 370 Nonionic None 37 370 10.0 774
Contrast Media Specifications ACR Manual on Contrast Media Brand Names: Iopromide = Ultravist Iohexol = Ominipaque Iodixanol = Visiopaque Product Chemical structure % Salt Concentration % Iodine Concentration Iodine + (mg/ml) Viscosity 37 (cps) Osmolality (mOsm/kg)  Iodixanol 270 Nonionic None 27 270 6.3 290 Iopromide 320 Nonionic None 32 320 11.8 290
 
Ideal CM in Angiography ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CM in Diagnostic Angiography
Organ Base Choice  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cerebral Angiography ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Renal Angiography ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Upper Extremity Angiography ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Lower Extremity Angiography ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Catheter
Major Adverse Effects in CM: ,[object Object],[object Object],[object Object],[object Object],[object Object]
CIN ,[object Object],[object Object],[object Object]
Serum Creatinine Measurement ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Gadolinium as an Alternative Agent ,[object Object],[object Object],[object Object]
Hydration ,[object Object]
 
www.newirsa.org ,[object Object]

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Contrast Agents in Angiography

  • 1. Contrast Agent in Angiography M. Fathi ;Bs Medical Imaging- TUMS October 2011- Kerman
  • 3.
  • 4.
  • 5. Intra-arterial administration delivers a higher concentration of CM to the kidney is true only for studies performed above the renal arteries.
  • 6.
  • 7. Greater volume of CM often administered in intra-arterial studies, particularly when diagnostic studies are combined with interventions.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12. Contrast Media Specifications ACR Manual on Contrast Media Product Chemical structure % Salt Concentration % Iodine Concentration Iodine + (mg/ml) Viscosity 37 (cps) Osmolality (mOsm/kg) Iohexol 240 Nonionic None 24 240 3.4 520 Iopromide 240 Nonionic <0.1 24 240 2.8 483 Iohexol 300 Nonionic None 30 300 6.3 672 Iopromide 300 Nonionic <0.1 30 300 4.9 607 Iohexol 350 Nonionic None 35 350 10.4 844 Iopromide 370 Nonionic None 37 370 10.0 774
  • 13. Contrast Media Specifications ACR Manual on Contrast Media Brand Names: Iopromide = Ultravist Iohexol = Ominipaque Iodixanol = Visiopaque Product Chemical structure % Salt Concentration % Iodine Concentration Iodine + (mg/ml) Viscosity 37 (cps) Osmolality (mOsm/kg) Iodixanol 270 Nonionic None 27 270 6.3 290 Iopromide 320 Nonionic None 32 320 11.8 290
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