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如何應用 AWS AIoT 幫助醫療產業面對 Covid-19
- 1. © 2020, Amazon Web Services, Inc. or its Affiliates.© 2020, Amazon Web Services, Inc. or its Affiliates.
- 2. © 2020, Amazon Web Services, Inc. or its Affiliates.
Young Yang, Machine Learning Specialist SA
如何應用 AWS AIoT 幫助醫療產業面對 Covid-19
Response to COVID-19, How AWS AIoT
Helps in Healthcare and Life Science
- 3. © 2020, Amazon Web Services, Inc. or its Affiliates.
Healthcare Challenges
- 4. © 2020, Amazon Web Services, Inc. or its Affiliates.
32 Patient records were breached in H1 2019 alone, more
than double that of the entire 2018 yearM
18 Rate at which computer processing
power doubles, according to Moore’s Lawmonths
54%
Percentage of hospital CEOs who say the transition from
volume to value is their biggest financial challenge
163ZB
Amount of data that will be generated globally in
2025; 10 times the 16.1 ZB of data generated in 2016
Industry
pressures
for
healthcare
- 5. © 2020, Amazon Web Services, Inc. or its Affiliates.
Healthcare IoT Abuse in FDA
2017
WannaCry
2018
Hacked cardiac
devices
70K+ devices
including computers,
MRI scanners, blood-
storage, refrigerators
and theatre equipment
Via Radio frequency
(RF):
heart failure or
heart rhythm
problems
2019
Insulin Pumps
Wireless or USB
change the pump’s
settings to either over-
deliver, or stop-delivery
2020
SweynTooth
Bluetooth Low Energy
(BLE)
Crash or deadlock the
devices. The device
may freeze and stop
working correctly
source:FDA
- 6. © 2020, Amazon Web Services, Inc. or its Affiliates.
Security and compliance are job zero
”
“Healthcare institutions
don’t have the time and
resources to devote to
cybersecurity that an
established cloud
provider might have…
Lee Kim, Director,
Privacy & Security,
HIMSS NA
50+ global compliance certifications
(e.g., HITRUST, ISO 9001),
accreditations and 110+HIPAA eligible
services
AWS industry-leading security teams
work 24/7, 365 days a year
Security enhancements from 1M+
customer experiences with tools like
Amazon Macie, Amazon GuardDuty
and IoT Defender
Security infrastructure built to satisfy
military, global banks and other high-
sensitivity organizations
- 7. © 2020, Amazon Web Services, Inc. or its Affiliates.
AWS IoT Device Defender
Security management for IoT devices
Audit IoT
resource
configuration
Continuously
monitor
device
behavior
Alerts on
AWS IoT
Console,
Amazon SNS,
Amazon
CloudWatch
Investigate
and mitigate
security
issues
Identify
anomalies
AWS IoT
Device Defender
- 8. © 2020, Amazon Web Services, Inc. or its Affiliates.
Anomaly detection—denial of service
Packets out Number of ports
and/or
suspicious port
communication
Communication
with suspicious IP
addresses
Bytes out
+ + +
10
01
- 9. © 2020, Amazon Web Services, Inc. or its Affiliates.
Anomaly detection—cloud infrastructure abuse
Message rate Communication
from suspicious
source IPs
Message size
+ +
- 10. © 2020, Amazon Web Services, Inc. or its Affiliates.
Protect your AWS accounts and workloads with intelligent
threat detection and continuous monitoring
Backdoor
Behavior
CryptoCurrency
PenTest
Persistence
Policy
PrivilegeEscalation
Recon
ResourceConsumption
Stealth
Trojan
Unauthorized
The service uses
machine learning,
anomaly detection, and
integrated threat
intelligence to identify
and prioritize potential
threats.
Amazon
GuardDuty
- 11. © 2020, Amazon Web Services, Inc. or its Affiliates.
120+
HIPAA Eligible Services Reference
https://aws.amazon.com/compliance/services-in-scope/
until 2020.4.30 latest information ref:
- 12. © 2020, Amazon Web Services, Inc. or its Affiliates.
Foundation Services
Compute Storage Database Networking
Infrastructure
Regions
Availability Zones
Edge Locations
Client-side Data
Encryption
Server-side Data
Encryption
Network Traffic
Protection
Platform, Applications, Identity & Access Management
Operating System, Network & Firewall Configuration
Customer content
之前要負責這麼
大的範圍
- 13. © 2020, Amazon Web Services, Inc. or its Affiliates.
AWS Foundation Services
Compute Storage Database Networking
AWS Global
Infrastructure Regions
Availability Zones
Edge Locations
Client-side Data
Encryption
Server-side Data
Encryption
Network Traffic
Protection
Platform, Applications, Identity & Access Management
Operating System, Network & Firewall Configuration
Customer App / Content / DataCustomerAWS 聚焦在
創新應用
AWS 全球專業的
安全團隊
AWS 提供專業的
工具協助客戶
- 14. © 2020, Amazon Web Services, Inc. or its Affiliates.
AWS Native Services
Cloud
Mgmt.
AWS
Service Catalog
AWS
CloudTrail
AWS
Config
AWS Trusted
Advisor
AWS X-Ray
AWS
OpsWorks
Amazon
CloudWatch
AWS
CloudFormation
AWSSnowball
AWSSMS
AWS
Systems
Manager
AWSKMS
IAM
AWSDMS
Amazon Inspector
Amazon Macie
Amazon
GuardDuty
Service
request
Inventory and
classification
Monitoring
and analytics
Packaging
and delivery*
Provisioning
and orchestration
Cost management and
resource optimization
Cloud migration,
backup, and DR
Identity, security,
and compliance
AWSConfigAWSCodeDeploy
AWSCodeCommit
AWSCodePipeline
AWSCodeBuild
Source: Gartner
Evaluation Criteria for
Cloud Management
Platforms and Tools
May 2018
- 15. © 2020, Amazon Web Services, Inc. or its Affiliates.
Cloud is new normal
in healthcare industries
- 16. © 2020, Amazon Web Services, Inc. or its Affiliates.
Provider Challenges
Value-based care
Increasing volume of
digital data
Continuous technology
advances
Sophisticated
security breaches
Trends
Extracting valuable
insights from data
becomes far more
complicated
Traditional IT model &
internal systems lack
necessary agility
Lack of resources to
implement data-driven
decision making
Patient data & compliance
standards vulnerable to
compromise
Provider Challenges
- 17. © 2020, Amazon Web Services, Inc. or its Affiliates.
Solutions Powered by AWS Benefits
Scalable architecture to
allow rapid and dynamic
data analysis
Hyperscale storage with
automated life cycle
management and deep
analytics tools
Flexible infrastructure
to leverage ever-
advancing technology
Automated security
and compliance
checks reduce risk
AWS Benefits
Extracting valuable insights
from data becomes far more
complicated
Traditional IT model &
internal systems lack
necessary agility
Lack of resources to
implement data-driven
decision making
Patient data & compliance
standards vulnerable to
compromise
Provider Challenges
Value-based care
Increasing volume of
digital data
Continuous technology
advances
Sophisticated
security breaches
Trends
- 18. © 2020, Amazon Web Services, Inc. or its Affiliates.
Impact of COVID-19 Pandemic
- 19. © 2020, Amazon Web Services, Inc. or its Affiliates.
Impact of COVID-19 pandemic on in-flight trials
Site staff
SitesPatients
CRA’s
Supply & DistributionManufacturing
Disruptors:
Travel limitations
Participant Fear
Supply chain disruption
Key challenges
Regulatory bodies have issued guidance for industry, investigators, and institutional review
boards for conducting clinical trials during the COVID-19 pandemic
- 20. © 2020, Amazon Web Services, Inc. or its Affiliates.
Impact of COVID-19 pandemic on other areas
• Drug supply: In some cases, drug (investigational medicinal product) supply will be disrupted, so
direct-to patient supply by certified distribution partners could address that need
• Remote Study Visits by HCPs: Not all medication can be self-administered and some trials require
more extensive patient examination
• Remote monitoring: If feasible, companies should consider remote monitoring of clinical endpoints
which will require seamless and compliant data integration (e.g. secure file sharing)
• Decentralized trials: Some companies offer fully integrated virtual trial platforms to address several
areas across the clinical development continuum
- 21. © 2020, Amazon Web Services, Inc. or its Affiliates.
What do you know about Amazon?
Unprecedented
SCALE
Hyper
SPEED
Relentless
INNOVATION
Customer
OBSESSION
- 24. © 2020, Amazon Web Services, Inc. or its Affiliates.
A Better, Simpler Pharmacy
- 25. © 2020, Amazon Web Services, Inc. or its Affiliates.
Optimized manufacturing,
automation, and fulfillment centers
Last mile delivery—direct to consumer
Data-driven supply chain and ML driven by AWS
Fulfillment logistics for degradable
products like vaccines and biologics
Currently doing fulfillment for Class I/II devices
Continuing innovation and disruption—
online vs traditional pharmacy
- 26. © 2020, Amazon Web Services, Inc. or its Affiliates.
COVID-19
Trigger Digital Transformation
- 27. © 2020, Amazon Web Services, Inc. or its Affiliates. https://aws.amazon.com/health/covid-19/
COVID-19 HPC Consortium AWS Diagnostic Development Initiative
- 28. © 2020, Amazon Web Services, Inc. or its Affiliates. https://aws.amazon.com/data-exchange/covid-19/
- 29. © 2020, Amazon Web Services, Inc. or its Affiliates.
https://registry.opendata.aws/
s3://covid19-lake
https://cord19.aws/
- 30. © 2020, Amazon Web Services, Inc. or its Affiliates.
QuickSight for COVID-19 Dashboard blog
- 31. © 2020, Amazon Web Services, Inc. or its Affiliates.
AI / ML Technologies reshaping healthcare
1
Voice
ASR/NLU
Vision
CV/DL/RL/NLP
2 3 4
Prediction
ML
Sensation
IoT
Automation
Bots/Robotics
Perception
AR/VR
Mobility
GPS/BTLE/5G
Trust
Blockchain
5 6 7 8
- 32. © 2020, Amazon Web Services, Inc. or its Affiliates.
Gartner, Magic Quadrant for Cloud AI Developer Services, Van Baker, Bern Elliot, Svetlana Sicular, Anthony Mullen, Erick Brethenoux, February 2020. ID G00431332. Gartner does not
endorse any vendor, product or service depicted in its research publications, and does not advise technology users to select only those vendors with the highest ratings. Gartner
research publications consist of the opinions of Gartner's research organization and should not be construed as statements of fact. Gartner disclaims all warranties, expressed or
implied, with respect to this research, including any warranties of merchantability or fitness for a particular purpose. The Gartner logo is a trademark and service mark of Gartner,
Inc., and/or its affiliates, and is used herein with permission. All rights reserved.
AWS Recognized as
a Leader in Cloud AI
Developer Services
- 33. © 2020, Amazon Web Services, Inc. or its Affiliates.
The AWS ML Stack
Broadest and most complete set of Machine Learning capabilities
VISION SPEECH TEXT SEARCH CHATBOTS PERSONALIZATION FORECASTING FRAUD DEVELOPMENT CONTACT CENTERS
Ground
Truth
Augmented
AI
ML
Marketplace
Neo
Built-in
algorithms
Notebooks Experiments
Model
training &
tuning
Debugger Autopilot
Model
hosting
Model Monitor
Deep Learning
AMIs & Containers
GPUs &
CPUs
AWS
Greengrass
Inferentia
(Inf1 instance)
FPGA
Amazon
Rekognition
Amazon
Polly
Amazon
Transcribe
+Medical
Amazon
Comprehend
+Medical
Amazon
Translate
Amazon
Lex
Amazon
Personalize
Amazon
Forecast
Amazon
Fraud Detector
Amazon
CodeGuru
AI SERVICES
ML SERVICES
ML FRAMEWORKS & INFRASTRUCTURE
Amazon
Textract
Amazon
Kendra
Contact Lens
For Amazon Connect
SageMaker Studio IDE
NEW
NEW! NEW! NEW! NEW!
NEW!
NEW! NEW! NEW! NEW! NEW!
Amazon SageMaker
RL Coach
E C 2 C 5
- 34. © 2020, Amazon Web Services, Inc. or its Affiliates.
Prognostication of COVID-19 on CT-Scans
https://cic.ubc.ca/covid-19-ct-scans/
Artificial Intelligence (AI) model to predict the likelihood of COVID-19 based on CT-Scans, University of British Columbia
Power by AWS
- 35. © 2020, Amazon Web Services, Inc. or its Affiliates.
Butterfly Networks improves access to ultrasound exams
(設備微型化,更容易攜帶到現場。)
Handheld whole-body
ultrasound system coupled
with a cloud-based,
intelligent data and analytics
platform designed to make
medical imaging universally
accessible and affordable
- 36. © 2020, Amazon Web Services, Inc. or its Affiliates.© 2020, Amazon Web Services, Inc. or its Affiliates.
COVID-19 Response Bot
- 37. © 2020, Amazon Web Services, Inc. or its Affiliates.
What are we hearing from customers?
• Patients - whether worried well, mildly symptomatic, or seriously unwell - are
looking to their healthcare providers for reliable information on COVID-19
• Call centers are seeing a spike in phone calls
• Some callers are frustrated with wait times and traveling to facility anyway
• Closing clinics and needing to reschedule non-critical cases are adding to
volumes
- 38. © 2020, Amazon Web Services, Inc. or its Affiliates.
COVID-19 Response Bot
Align
Scope
Assist Customer in deploying a fully functional COVID-19 Response Bot
2 to 5 days, to handle triage* based questions powered by Amazon Lex, through
at least one of multiple channels (phone call, web messaging, mobile app
messaging, or social media chatbot) * Triage - A process of determining the
priority of next steps based on patient’s condition.
Key Activities
Discover Customer’s use cases, requirements and existing technology.
Introduce Lex Bot’s architecture and implementation guidelines.
Review modification required in COVID19 responses based on publicly
available triage
Assist in deploying one (1) instance of a fully functional COVID-19
Response Bot powered by Amazon Lex for one channel (phone call, web
messaging, mobile app messaging) including logging, customized
responses, configuration and validation.
Provide documented high level solution architecture, deployment guides
and operational best practices
COVID-19 Response Bot blog
Outcome
One (1) instance of fully
functional COVID-19
Response Bot to handle
triage based questions
powered by Amazon Lex
Duration
1 week engagement
- 39. © 2020, Amazon Web Services, Inc. or its Affiliates.
COVID-19 Response Bot Reference Architecture
- 40. © 2020, Amazon Web Services, Inc. or its Affiliates.
Triage Protocol – Sample
Example of the Screening Questions
Age m <18 m 18-60 m Over 60
Have you been in contact with someone know to have coronavirus (COVID-19)?
m Yes m No
Have you been told by a public health official or your employer you may have
been exposed to coronavirus (COVID-19) m Yes m No
Are you experiencing any of the following symptoms?
m New Cough
m Fever > 100.4
m New shortness of breath
m New sore throat
m New muscle aches (myalgia)
Have your recently been in a skilled nursing facility? m Yes m No
Do you have any of the following medical conditions (comorbidities)?
m Heart disease such as congestive heart failure?
m Lung disease such as COPD or emphysema
m Liver disease
m Kidney disease
Are you immunocompromised? m Yes m No
Logic
New onset cough Yes refer for evaluation through telehealth,
Referred by public health official or employer Yes refer for evaluation
through telehealth
We help you convert your
triage protocol into rules
that are easy to deploy and
update
- 42. © 2020, Amazon Web Services, Inc. or its Affiliates.
HIPAA-eligible patient engagement
opportunities through voice
Opportunities for clinical trials, digital
therapeutics, real-world evidence collection
Personalize your engagements with the
customization engine driven by AWS ML
Now applied to life sciences
- 44. © 2020, Amazon Web Services, Inc. or its Affiliates. https://www.amazon.com/b?ie=UTF8&node=21155035011
"Alexa, what do I do if I think I have
COVID-19?”
You can ask Alexa for a series of
questions about your travel history,
symptoms, and possible exposure.
Based on your responses, Alexa will
provide CDC guidance given your risk
level and symptoms.
“Alexa, sing a song for 20 seconds“
Timing is everything, so sing along
while you wash your hands.