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Alcohol in Ireland.
    Major health burden.
   Major economic burden.
     Major opportunity.

            Prof Frank Murray

              Registrar RCPI

Consultant Gastroenterologist/Hepatologist,
        Beaumont Hospital/RCSI,
                 Dublin 9
Policies that reduce the availability
         of alcohol though:


  Price increases
                   or
  Reducing outlets and hours of
  sale
Have been shown to be effective
• Europe is the heaviest drinking region in
  the world
• Alcohol is the main cause of liver disease
  in Europe
• The prevalence of alcoholic liver disease
  is rising in Ireland
Problems addressing the alcohol
        problem in Ireland!!!!
• Drinking alcohol can be harmless, in
  contrast to cigarettes

• Alcohol is strongly rooted in our society

• The alcohol industries receive the majority
  of their turnover in UK from harmful and
  hazardous drinkers
Alcohol in Europe
• Europe is the highest drinking region in
  the world
• 200,000 deaths per year
• Cost €125 billion per year. 1.3% of GDP
• Third commonest cause of premature
  death and disability

• Main cause of liver disease and death
DALY (Disability adjusted life
             year)
• The sum of the life years lost due to
  premature death or years lived in disability
Alcohol cause huge health problems
• WHO:
  – 4% of global mortality
  – 5% of global DALY


• Europe worse
  – 7% mortality
  – 12% of DALY
Alcohol cause huge health problems
• Worse in males: 17% of DALYs( vs 4%)

• Worst in young males

• Alcohol cause 35% of deaths aged 35-
  50
Alcohol responsibility for many
           youth deaths
• 25% of male

• 10% of female
Major disease burdens attributable
            to alcohol
Main cause of alcohol DALY
• Liver disease

• 75% men



• 85% women
• There is a direct correlation between
  amount of alcohol consumed and
  cirrhosis mortality
CIRRHOSIS AND PORTAL HYPERTENSION



            Cirrhosis
               and
       Portal Hypertension
SURVIVAL TIMES IN CIRRHOSIS




     Decompensation in cirrhosis
         Shortens Survival
               100


                 80                                                         Median survival
                                                                            Median survival
                                                                              ~ 9 years
                                                                              ~ 9 years

                 60                                              All patients
                                                                with cirrhosis
Probability of
   survival
                 40


                 20
                                                      Decompensated         Median survival
                                                                            Median survival
                                                         cirrhosis           ~ 1.6 years
                                                                              ~ 1.6 years
                 0
                      0   20    40      60       80       100   120   140   160   180
                                                 Months
Gines et. al., Hepatology 1987;7:122
Mortality due to cirrhosis in Ireland
There is a big human cost here
•   Ill and dying patients
•   Often young
•   Often little opportunity to change
•   Families
Does not end there
•   Absenteeism
•   Loss of professional performance
•   Domestic violence
•   Unhappiness
3 main types of alcohol misuse
• Hazardous
• Harmful
• Dependent drinking.
Hazardous drinking
• Drinks over the recommended weekly limit
  of alcohol
• 21/17 units for men and
• 14/11 units for women.

• It is also possible to drink hazardously by
  binge drinking, even if within weekly limit.
Harmful drinking
• Drinks more than the recommended weekly
  maximum amount of alcohol and experiences
  health problems that are directly related to alcohol.
• Cirrhosis
• depression
• an alcohol-related accident, such as a head injury
• acute pancreatitis (inflammation of the pancreas)
• high blood pressure
• some types of cancer
• heart disease
Dependent drinking

• Both physically and psychologically addictive
• Become dependent on it
• Feels unable to function without alcohol
• Consumption of alcohol becomes an
  important, or sometimes the most important,
  factor in their life
• Can experience withdrawal symptoms (both
  physical and psychological) if they suddenly
  stop drinking alcohol.
Binge drinking
• 4 (female)
• 5 (male)
• units in 2h

        – or
• 8 (male)
• 6 (female)
• units in 24 hours

• Rapidly increasing in prevalance
So most alcohol consumption is
   mostly drunk safely?…..
• 75% of alcohol consumed in UK is by
  hazardous and harmful drinkers in the UK
Absolute risk of death from alcohol-
          related disease
Adult alcohol consumption
Heavy episodic drinking of at least 60g
of pure alcohol in last 7 days (women)
Irish consumption
• 11.9 litres of alcohol per adult (>15y) in
  2010

• Over half Irish drinkers have a harmful
  drinking pattern

• Much more affordable
Irish costs of alcohol
• €3.7 billion

• Healthcare €1.2 billion (8% of total)

• Approx 2,000 hospital beds per night

• 7% of GP costs
• 30% of Emergency Department costs
Fundamental problem in Ireland
•   Too much alcohol
•   Binge drinking
•   Availability
•   Number of outlets
•   Opening hours
Availability
Supermarkets
•   Promotions
•   Special offers
•   Packaging in larger units
•   Not quarantined, all over the shop
Concerts
Sports sponsorship
Under-age drinking
Marketing towards young people
Options
• Do nothing
• Do “something”
• Take thought-through series of steps.
  Leads to immediate health social and
  political gains
Systematic reviews and meta-analyses.
          Proven policies.
• Policies regulating the environment in
  which alcohol is marketed (particularly its
  price and availability) are effective in
  reducing alcohol-related harm.
• Making alcohol more expensive and less
  available, and banning alcohol
  advertising, are highly cost-effective
  strategies to reduce harm.
Key messages

A substantive evidence base of systematic
reviews and meta-analyses inform alcohol
policy
Making alcohol more
expensive and less
available are highly cost-
effective strategies to reduce
harm
• Banning of alcohol advertising
• Drink-driving countermeasures
• Individually-directed
  interventions to drinkers already
  at risk
 are also cost-effective approaches
School-based education does
not reduce harm, but public
information and education
programmes can increase
attention to alcohol on public
and political agendas
If more stringent alcohol policies
are not put into place, global
alcohol-related harm is likely to
continue to increase
Actions
• Reduce number of outlets dramatically
• Increase cost-minimum unit pricing
• Expand and enforce legislation re alcohol
  consumption in public and public order
  offences

• All of proven international proven benefit
Successful legislated constructive
     social changes in Ireland


• Smoking ban
• Reduction in alcohol driving
  limit
• Cycling helmets
RCPI alcohol group
• RCPI established a national policy group to
  address the health and social burden of
  alcohol in Ireland.
• The policy group brings together experts from
  a wide range of medical specialist bodies to
  speak with one voice on the issue of alcohol,
  to support
• Propose practical solutions backed up by a
  robust, international evidence base
• Focused on reducing the harm caused by
  alcohol to health and society.
Policies that reduce the availability
          of alcohol though:


  Price increases
                   and
  Reducing outlets and hours of
  sale
Have been shown to be effective

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Alcohol-related harm in Ireland - a health perspective

  • 1. Alcohol in Ireland. Major health burden. Major economic burden. Major opportunity. Prof Frank Murray Registrar RCPI Consultant Gastroenterologist/Hepatologist, Beaumont Hospital/RCSI, Dublin 9
  • 2. Policies that reduce the availability of alcohol though: Price increases or Reducing outlets and hours of sale Have been shown to be effective
  • 3. • Europe is the heaviest drinking region in the world • Alcohol is the main cause of liver disease in Europe • The prevalence of alcoholic liver disease is rising in Ireland
  • 4. Problems addressing the alcohol problem in Ireland!!!! • Drinking alcohol can be harmless, in contrast to cigarettes • Alcohol is strongly rooted in our society • The alcohol industries receive the majority of their turnover in UK from harmful and hazardous drinkers
  • 5. Alcohol in Europe • Europe is the highest drinking region in the world • 200,000 deaths per year • Cost €125 billion per year. 1.3% of GDP • Third commonest cause of premature death and disability • Main cause of liver disease and death
  • 6. DALY (Disability adjusted life year) • The sum of the life years lost due to premature death or years lived in disability
  • 7. Alcohol cause huge health problems • WHO: – 4% of global mortality – 5% of global DALY • Europe worse – 7% mortality – 12% of DALY
  • 8. Alcohol cause huge health problems • Worse in males: 17% of DALYs( vs 4%) • Worst in young males • Alcohol cause 35% of deaths aged 35- 50
  • 9. Alcohol responsibility for many youth deaths • 25% of male • 10% of female
  • 10. Major disease burdens attributable to alcohol
  • 11. Main cause of alcohol DALY • Liver disease • 75% men • 85% women
  • 12. • There is a direct correlation between amount of alcohol consumed and cirrhosis mortality
  • 13. CIRRHOSIS AND PORTAL HYPERTENSION Cirrhosis and Portal Hypertension
  • 14. SURVIVAL TIMES IN CIRRHOSIS Decompensation in cirrhosis Shortens Survival 100 80 Median survival Median survival ~ 9 years ~ 9 years 60 All patients with cirrhosis Probability of survival 40 20 Decompensated Median survival Median survival cirrhosis ~ 1.6 years ~ 1.6 years 0 0 20 40 60 80 100 120 140 160 180 Months Gines et. al., Hepatology 1987;7:122
  • 15. Mortality due to cirrhosis in Ireland
  • 16. There is a big human cost here • Ill and dying patients • Often young • Often little opportunity to change • Families
  • 17. Does not end there • Absenteeism • Loss of professional performance • Domestic violence • Unhappiness
  • 18. 3 main types of alcohol misuse • Hazardous • Harmful • Dependent drinking.
  • 19. Hazardous drinking • Drinks over the recommended weekly limit of alcohol • 21/17 units for men and • 14/11 units for women. • It is also possible to drink hazardously by binge drinking, even if within weekly limit.
  • 20. Harmful drinking • Drinks more than the recommended weekly maximum amount of alcohol and experiences health problems that are directly related to alcohol. • Cirrhosis • depression • an alcohol-related accident, such as a head injury • acute pancreatitis (inflammation of the pancreas) • high blood pressure • some types of cancer • heart disease
  • 21. Dependent drinking • Both physically and psychologically addictive • Become dependent on it • Feels unable to function without alcohol • Consumption of alcohol becomes an important, or sometimes the most important, factor in their life • Can experience withdrawal symptoms (both physical and psychological) if they suddenly stop drinking alcohol.
  • 22. Binge drinking • 4 (female) • 5 (male) • units in 2h – or • 8 (male) • 6 (female) • units in 24 hours • Rapidly increasing in prevalance
  • 23. So most alcohol consumption is mostly drunk safely?….. • 75% of alcohol consumed in UK is by hazardous and harmful drinkers in the UK
  • 24. Absolute risk of death from alcohol- related disease
  • 26. Heavy episodic drinking of at least 60g of pure alcohol in last 7 days (women)
  • 27.
  • 28. Irish consumption • 11.9 litres of alcohol per adult (>15y) in 2010 • Over half Irish drinkers have a harmful drinking pattern • Much more affordable
  • 29. Irish costs of alcohol • €3.7 billion • Healthcare €1.2 billion (8% of total) • Approx 2,000 hospital beds per night • 7% of GP costs • 30% of Emergency Department costs
  • 30.
  • 31. Fundamental problem in Ireland • Too much alcohol • Binge drinking • Availability • Number of outlets • Opening hours
  • 33. Supermarkets • Promotions • Special offers • Packaging in larger units • Not quarantined, all over the shop
  • 35.
  • 37.
  • 40. Options • Do nothing • Do “something” • Take thought-through series of steps. Leads to immediate health social and political gains
  • 41. Systematic reviews and meta-analyses. Proven policies. • Policies regulating the environment in which alcohol is marketed (particularly its price and availability) are effective in reducing alcohol-related harm. • Making alcohol more expensive and less available, and banning alcohol advertising, are highly cost-effective strategies to reduce harm.
  • 42. Key messages A substantive evidence base of systematic reviews and meta-analyses inform alcohol policy
  • 43. Making alcohol more expensive and less available are highly cost- effective strategies to reduce harm
  • 44. • Banning of alcohol advertising • Drink-driving countermeasures • Individually-directed interventions to drinkers already at risk are also cost-effective approaches
  • 45. School-based education does not reduce harm, but public information and education programmes can increase attention to alcohol on public and political agendas
  • 46. If more stringent alcohol policies are not put into place, global alcohol-related harm is likely to continue to increase
  • 47. Actions • Reduce number of outlets dramatically • Increase cost-minimum unit pricing • Expand and enforce legislation re alcohol consumption in public and public order offences • All of proven international proven benefit
  • 48. Successful legislated constructive social changes in Ireland • Smoking ban • Reduction in alcohol driving limit • Cycling helmets
  • 49. RCPI alcohol group • RCPI established a national policy group to address the health and social burden of alcohol in Ireland. • The policy group brings together experts from a wide range of medical specialist bodies to speak with one voice on the issue of alcohol, to support • Propose practical solutions backed up by a robust, international evidence base • Focused on reducing the harm caused by alcohol to health and society.
  • 50. Policies that reduce the availability of alcohol though: Price increases and Reducing outlets and hours of sale Have been shown to be effective

Hinweis der Redaktion

  1. Slide 1 CIRRHOSIS AND PORTAL HYPERTENSION
  2. Slide 16 SURVIVAL TIMES IN CIRRHOSIS In a prospective cohort study of 257 patients with compensated cirrhosis of different etiologies, median survival for all patients (including those who developed decompensation) was approximately 9 years, while it was significantly lower in patients who developed a decompensating event (ascites, jaundice, encephalopathy or hemorrhage), in whom the median survival was only 1.6 years. Gines et al. Hepatology 1987; 7:122