Médico brasileiro e radicado no Canadá, Tirone David é novo membro Honorário Estrangeiro da Academia Nacional de Medicina. Em sua palestra de posse, falou sobre criatividade na medicina e em outros campos do saber.
Na área de medicina, David relatou sua experiência própria de como usou a criatividade para solucionar casos críticos na sala de cirurgia – culminando em descobertas que revolucionaram a cirurgia cardíaca em todo o mundo. Leia a matéria sobre a apresentação em: http://www.anm.org.br/conteudo_view.asp?id=1299
9. Model of the DNA
Watson & Crick
Nature 1953; 171:737-8
10. "Father of Genetics"
Gregor Mendel Son of a farmer who became a
catholic monk, conducted an
experiment that involved growing
thousands of pea plants, which
1822-1884
led to the discovery of genes. His
ideas were published in 1866 but
went largely unrecognized until
1900.
11. Virulent
+ = Death
Frederick Griffith Pneumococcus
1881 - 1941
Non-virulent
+ = Live
Pneumococcus
Heated virulent
+ = Live
Pneumococcus
Non-virulent +
Experiments with + heated virulent = Death
Pneumococcus in 1928 Pneumococci
12. Non-virulent
++ = Death
Oswald Avery heated
1877 - 1955 virulent
Pneumococci +
Non-virulent
Virulent with
destroyed lipids,
+ ribonucleic acids, = Death
carbohydrates,
and proteins
Non-virulent +
Virulent with
+ destroyed = Live
deoxyribonucleic
Experiments with acids
Pneumococcus in 1935
13. Erwin Chargaff In 1950 he concluded that there must
1905-2002 be as many types of DNA as there are
different species. The number of
purine
bases (adenine and guanine) was equal
to the number of pyrimidine bases
(cytosine and thymine). The number of
adenine bases was equal to the number
of thymine bases and the number of
guanine bases was equal the number of
cytosine bases.
Chargaff’s rule: A = T, and G = C
14. Linus Pauling
1901-1994
In May 1951, he described the structures of a
number of proteins, including the structure of
the single most important basic form of protein
chain, the alpha helix (a hydrogen-bonded
helical chain that is a structural component of
most proteins).
15. Cavendish Laboratory Randall’s Laboratory
Cambridge King’s College
James Francis Rosalind Maurice
Watson Crick Franklin Wilkins
1928- 1916-2004 1920-58 1916-2004
25. Creativity results from the interaction of
a system composed of three elements:
Domain
Field
Person
26. Domain is an area of our culture
Examples of domains:
Medicine
Heart valve surgery
Mitral valve surgery
27. Field = gatekeepers of a domain
Without the assessment of competent outsiders there is no
reliable way to decide whether the claims of a self-styled
creative person are valid.
40. Endocardial patch for LV rupture
Reconstruction the mitral annulus
Reconstruction of the base of the heart
Reconstruction of the LV wall
41. Peer-reviewed publications
Left ventricular rupture after mitral valve replacement: endocardial repair with
pericardial patch.
David TE. J Thorac Cardiovasc Surg. 1987 Jun;93(6):935-6
Reconstruction of the mitral anulus.
David TE, Feindel CM. Circulation. 1987 Sep;76(3 Pt 2):III102-
Postinfarction ventricular septal rupture: repair by endocardial patch with infarct
exclusion.
David TE, Dale L, Sun Z. J Thorac Cardiovasc Surg. 1995 Nov;110(5):1315-22
.... Plus 28 other publications on this topic
43. Mitral Valve Surgery
LV function after MV repair is better than after MVR
Gore-Tex for replacement of chordae tendineae
Techniques of MV repair in Barlow’s valves
49. Christopher Langan
Born in San Francisco, 1952
“The smartest man in America"
IQ = 195 - 210
He rose to prominence in 1999
while working as a bar bouncer
in Long Island
The Cognitive-Theoretic Model
of the Universe
50. Gladwell:
“No one –not even rock stars,
not professional athletes, not
software millionaires, and not
even geniuses – ever makes
it alone”
51. The End of Europe’s Middle Age
Florence, Italy – Renaissance’s Birthplace
52. Where do creative ideas come from?
Come from the past
Come from previous knowledge and experiences
Creative works begin in continuity with the past