Essential medicines are those that satisfy priority health needs and are selected based on disease prevalence, efficacy, safety, and cost-effectiveness. They must be consistently available in appropriate forms and quality and affordable. The concept of essential medicines incorporates regular updates to reflect new treatments and resistance patterns, as well as ensuring drug quality and better medicines. Rational prescribing involves considering whether medication is necessary, the expected effect, administration method, side effects, and whether benefits outweigh risks.

4. Rational Therapeutics “ Poisons in small doses are the best medicines and useful medicines in too large doses are poison’s” William Withering.