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2. INTRODUCTION

3. WHAT IS PYRETHRUM?

5. PROPERTIES
 Ecofriendly
 Quick action
 Low toxicity
 Multipurpose
√ Repellant
√ Flushing agent
 No development of insect immunity

6. MECHANISM OF ACTION

7. METHOD OF APPLICATION
 Space spray
 Kills adult mosquitoes & other insects
 0.5 – 1 oz of solution/1000 cu ft of space
 After spraying windows & doors should be
closed for not less than 30 mins

8. SYNERGESTIC EFFECT??
 Pyrethrum + DDT or Piperonyl
(low toxicity) butoxide
Common formulation of PYRETHRIN
(Enhanced toxicity)

9. SYNTHETIC PYRETHROIDS
 Replace the natural pyrethrins
 10 times more effective
 Examples:
1) Lambda cyhalothrin(cyano group)
2) Permethrin
3) Tetramethrin
4) Rosethrin
5) Proparthin

10. MECHANISM OF ACTION
 Affect CNS
 Prolong deactivation of
voltage gated Na channel
Prolonged excitation of fibres
 Lambda cyhalothrin-more neurotoxic
-more selectivity

11. SIDE EFFECTS
PYRETHROIDS
 Inhalation- coughing,wheezing,shortness of
breath
 Skin- itching,rash,paraesthesia(lamda
cyhalothrin)
 Neurotoxic effect-tremor, incoordination,
increased body temp
 Long term effects-disrupt endocrine system
-carcinogen(thyroid gland)

12. PIPERONYL BUTOXIDE
 Skin ulceration
 Eye irritation
 Long term-carcinogen

13. THANK YOU